lysine has been researched along with alpha-synuclein in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (30.95) | 29.6817 |
| 2010's | 27 (64.29) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fink, AL; Han, S; Kaylor, J; Rajamani, S; Zhou, F; Zhu, M | 1 |
| Devreese, B; Fésüs, L; Nemes, Z; Steinert, PM; Van Beeumen, J | 1 |
| Axelsen, PH; Englander, SW; Giasson, BI; Graves, CL; Greenbaum, EA; Lupoli, MA; Lynch, DR; Mishizen-Eberz, AJ | 1 |
| Chen, L; Doss-Pepe, EW; Madura, K | 1 |
| Chew, KC; Chung, KK; Dawson, TM; Dawson, VL; Engelender, S; Lim, KL; Ross, CA; Smith, W; Tan, JM; Tanaka, Y; Wang, C; Zhang, Y | 1 |
| Galvin, JE; Pandey, N; Schmidt, RE | 1 |
| Dorval, V; Fraser, PE | 1 |
| Dalfó, E; Ferrer, I | 1 |
| Fei, E; Iwata, A; Jia, N; Liu, C; Nukina, N; Tao, R; Wang, G; Wang, H; Zhou, J | 1 |
| Avraham, E; Engelender, S; Haskin, J; Liani, E; Manov, I; Rott, R; Shainskaya, A; Shani, V; Szargel, R | 1 |
| Grzonka, Z; Jankowska, E; Kowalik-Jankowska, T; Rajewska, A | 1 |
| Julian, RR; Ly, T | 1 |
| Chan, HY; Chung, KK; Lee, FK; Lee, YW; Wan, OW; Wong, AK | 1 |
| Bax, A; Bodner, CR; Dobson, CM; Maltsev, AS | 1 |
| Chen, L; He, R; Wang, X; Wei, Y | 1 |
| Choi, YG; Lim, S | 1 |
| Churchill, DG; Ha, Y; Kim, K; Liew, H; Park, HY; Suh, YH | 1 |
| Gomez-Esteban, JC; Lezcano, E; Molano, A; Somme, JH; Tijero, B; Zarranz, JJ | 1 |
| Goldberg, AL; Hourez, R; Jung, JW; Kim, HT; Kim, KP; Tofaris, GK | 1 |
| Bousset, L; Egge-Jacobsen, W; Falnes, PØ; Jakobsson, ME; Kernstock, S; Melki, R; Moen, A | 1 |
| Dettmer, U; Newman, AJ; Selkoe, D | 1 |
| Acharya, S; Attar, A; Bitan, G; Ivanova, MI; Klärner, FG; Lapidus, LJ; Loo, JA; Safaie, BM; Schrader, T; Wongkongkathep, P | 1 |
| Adame, A; Campioni, S; Gage, FH; Gerez, J; Jensen, PH; Mante, M; Masliah, E; Nuber, S; Overk, CR; Patrick, C; Picotti, P; Riek, R; Rockenstein, E; Trejo-Morales, M; Ubhi, K; Winkler, J; Winner, B | 1 |
| Anan, T; Aoki, M; Baba, T; Fukuda, M; Geisler, S; Hasegawa, T; Kikuchi, A; Konno, M; Miura, E; Nakao, M; Oshima, R; Sugeno, N; Takeda, A; Tanaka, N; Wakabayashi, K | 1 |
| Braus, GH; Fraser, PE; Kleinknecht, A; Outeiro, TF; Popova, B; Shahpasandzadeh, H | 1 |
| Bubacco, L; Casella, L; De Ricco, R; Dell'Acqua, S; Gaggelli, E; Mangani, S; Valensin, D; Valensin, G | 1 |
| Araujo, GD; Coelho-Cerqueira, E; Domont, GB; Eliezer, D; Follmer, C; Pinheiro, AS; Yatabe-Franco, DY | 1 |
| Bubacco, L; Plotegher, N | 1 |
| Abeywardana, T; Galesic, A; Lewis, YE; Lin, YH; Pratt, MR | 1 |
| Bax, A; Lee, JH; Ying, J | 1 |
| Jäckel, S; Kahle, PJ; Schulze-Hentrich, J; Sugeno, N; Voigt, A; Wassouf, Z | 1 |
| Bellotti, V; De Franceschi, G; de Laureto, PP; Fecchio, C; Proukakis, C; Schapira, AHV; Sharon, R | 1 |
| Antas, P; Becker, S; de Oliveira, RM; Enguita, FJ; Fauvet, B; Fonseca-Ornelas, L; Francelle, L; Gerhardt, E; Guerreiro, P; Kügler, S; Lashuel, HA; Lázaro, DF; Marijanovic, Z; Martinho, R; Moniot, S; Munari, F; Outeiro, TF; Pais, TF; Penque, D; Pinho, R; Steegborn, C; Szegö, ÉM; Tong, Q; Vicente Miranda, H; Zweckstetter, M | 1 |
| Bax, A; Levine, RL; Werner-Allen, JW | 1 |
| de Moraes, MC; Fernandes, L; Foguel, D; Grimster, NP; Kelly, JW; Magalhães, AV; Moraes, N; Palhano, FL; Romão, L; Sagrillo, FS | 1 |
| Loskarn, S; Masliah, E; Regensburger, M; Rockenstein, E; Schreglmann, SR; Stoll, S; Winner, B; Xiang, W | 1 |
| Bhasne, K; Jain, N; Mukhopadhyay, S; Sebastian, S | 1 |
| Guhathakurta, S; Je, G; Kim, YS; Ko, HS; Yun, SP | 1 |
| Deng, Y; Jiang, B; Maupin-Furlow, JA; Moskovitz, J; Rankin, CL; Richter, ML; Toyo-Oka, K | 1 |
| Achille, A; Bartels, T; Fonseca-Ornelas, L; Jiang, H; Langen, R; Patel, DS; Pitino, JC; Powers, AE; Rovere, M; Varkey, J | 1 |
| Amagai, R; Hashimoto, N; Nagano, H; Okado-Matsumoto, A; Otomo, R; Sakakibara, R; Tanaka, T; Yoshioka, S | 1 |
| Bastos Mendes, LF; Bittencourt, RR; Gelain, DP; Moreira, JCF; Outeiro, TF | 1 |
2 review(s) available for lysine and alpha-synuclein
| Article | Year |
|---|---|
Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehydes; alpha-Synuclein; Brain; Dopamine; Humans; Lysine; Metabolism; Neurodegenerative Diseases; Neurons | 2016 |
RAGE Against the Glycation Machine in Synucleinopathies: Time to Explore New Questions.
Topics: alpha-Synuclein; Animals; Lysine; Maillard Reaction; Neuroinflammatory Diseases; Parkinson Disease; Receptor for Advanced Glycation End Products; Synucleinopathies | 2023 |
40 other study(ies) available for lysine and alpha-synuclein
| Article | Year |
|---|---|
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.
Topics: alpha-Synuclein; Anaerobiosis; Benzothiazoles; Circular Dichroism; Escherichia coli; Flavanones; Flavonoids; Humans; Light; Lysine; Microscopy, Atomic Force; Molecular Weight; Nerve Tissue Proteins; Oxidation-Reduction; Protein Conformation; Quinones; Scattering, Radiation; Solubility; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Synucleins; Thiazoles; Tyrosine | 2004 |
Cross-linking of ubiquitin, HSP27, parkin, and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimer's neurofibrillary tangles.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dipeptides; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Heat-Shock Proteins; Hippocampus; HSP27 Heat-Shock Proteins; Humans; Inclusion Bodies; Lysine; Macromolecular Substances; Male; Molecular Chaperones; Neoplasm Proteins; Nerve Tissue Proteins; Neurofibrillary Tangles; Neurofilament Proteins; Plaque, Amyloid; Proteasome Endopeptidase Complex; Solubility; Synucleins; tau Proteins; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
The E46K mutation in alpha-synuclein increases amyloid fibril formation.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Amyloid; Blotting, Western; Calpain; Chromatography, Gel; Circular Dichroism; DNA, Complementary; Glutamic Acid; Humans; Kinetics; Lysine; Microscopy, Electron; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Protein Conformation; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synucleins; Time Factors | 2005 |
Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains.
Topics: alpha-Synuclein; Dimerization; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Escherichia coli; Glutathione Transferase; Humans; Lysine; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Mutation; Nerve Tissue Proteins; Parkinson Disease; Proteasome Endopeptidase Complex; Protein Binding; Ribosomes; Synucleins; Time Factors; Ubiquitin; Ubiquitin-Protein Ligases | 2005 |
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.
Topics: alpha-Synuclein; Carrier Proteins; Catalysis; Cell Line; Gene Expression; Humans; Kidney; Lewy Bodies; Lysine; Nerve Tissue Proteins; Parkinson Disease; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Synucleins; Transfection; Ubiquitin; Ubiquitin-Protein Ligases | 2005 |
The alpha-synuclein mutation E46K promotes aggregation in cultured cells.
Topics: alpha-Synuclein; Blotting, Western; Cell Aggregation; Cell Line, Tumor; Fluorescent Antibody Technique; Glutamic Acid; Green Fluorescent Proteins; Humans; Lysine; Microscopy, Electron, Transmission; Mutagenesis; Mutation; Neuroblastoma; Transfection | 2006 |
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein.
Topics: alpha-Synuclein; Blotting, Western; Cell Line; Epitopes; Humans; Lysine; Microtubules; Neurodegenerative Diseases; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; tau Proteins; Transfection; Ubiquitin; Ubiquitins | 2006 |
Early alpha-synuclein lipoxidation in neocortex in Lewy body diseases.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Female; Humans; Immunoprecipitation; Lewy Body Disease; Lysine; Male; Middle Aged; Neocortex; Oxidation-Reduction; Parkinson Disease | 2008 |
Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis.
Topics: alpha-Synuclein; Animals; Immunoblotting; Inclusion Bodies; Lewy Bodies; Lysine; Mice; Mutation; Neuroblastoma; Phosphorylation; Subcellular Fractions; Tumor Cells, Cultured; Ubiquitin | 2007 |
Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells.
Topics: alpha-Synuclein; Cell Line, Tumor; Dopamine; Humans; Inclusion Bodies; Lewy Bodies; Lysine; Mass Spectrometry; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Neurons; Nuclear Proteins; Protein Binding; Ubiquitin; Ubiquitin-Protein Ligases | 2008 |
Products of Cu(II)-catalyzed oxidation of alpha-synuclein fragments containing M1-D2 and H50 residues in the presence of hydrogen peroxide.
Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Catalysis; Cations, Divalent; Chromatography, High Pressure Liquid; Copper; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Lysine; Methionine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfones | 2008 |
Protein-metal interactions of calmodulin and alpha-synuclein monitored by selective noncovalent adduct protein probing mass spectrometry.
Topics: alpha-Synuclein; Aluminum; Calcium; Calmodulin; Copper; Crown Ethers; Lysine; Mass Spectrometry; Protein Binding | 2008 |
The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Autophagy; Cell Line, Tumor; Cells, Cultured; Cytoprotection; Disease Models, Animal; Drosophila melanogaster; Humans; Lewy Bodies; Lysine; Lysosomes; Nerve Degeneration; Neurons; Parkinson Disease; Polymers; Proteasome Endopeptidase Complex; Protein Folding; Substantia Nigra; Ubiquitin; Ubiquitination | 2009 |
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine | 2010 |
Ribosylation rapidly induces alpha-synuclein to form highly cytotoxic molten globules of advanced glycation end products.
Topics: alpha-Synuclein; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Circular Dichroism; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Humans; Intracellular Space; Kinetics; Lysine; Protein Multimerization; Protein Structure, Quaternary; Reactive Oxygen Species; Ribose; Spectrometry, Fluorescence; Time Factors | 2010 |
N(ɛ)-(carboxymethyl)lysine linkage to α-synuclein and involvement of advanced glycation end products in α-synuclein deposits in an MPTP-intoxicated mouse model.
Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glycation End Products, Advanced; Lysine; Mice; Mice, Inbred C57BL; MPTP Poisoning; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2010 |
Interplay of salicylaldehyde, lysine, and M2+ ions on α-synuclein aggregation: cancellation of aggregation effects and determination of salicylaldehyde neurotoxicity.
Topics: Aldehydes; alpha-Synuclein; Cell Line, Tumor; Cell Survival; Copper; Humans; Lysine; Manganese; Neurons; Protein Binding; Zinc | 2011 |
Initial neuropsychological impairments in patients with the E46K mutation of the α-synuclein gene (PARK 1).
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Cognition Disorders; Disease Progression; Family Health; Female; Glutamine; Humans; Longitudinal Studies; Lysine; Male; Mutation; Neuropsychological Tests; Parkinson Disease; Psychiatric Status Rating Scales; Time Factors | 2011 |
Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway.
Topics: alpha-Synuclein; Amino Acid Sequence; Animals; Binding Sites; Brain; Cell Line; Endosomal Sorting Complexes Required for Transport; Endosomes; HEK293 Cells; Humans; In Vitro Techniques; Lewy Bodies; Locus Coeruleus; Lysine; Lysosomes; Mice; Molecular Sequence Data; Nedd4 Ubiquitin Protein Ligases; Parkinson Disease; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substantia Nigra; Substrate Specificity; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitination | 2011 |
Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.
Topics: alpha-Synuclein; Amino Acid Motifs; Amino Acid Sequence; Biomarkers; Catalysis; Cloning, Molecular; Computational Biology; DNA Modification Methylases; HEK293 Cells; HSP70 Heat-Shock Proteins; Humans; Lysine; Mass Spectrometry; Molecular Sequence Data; Open Reading Frames; Peptides; Protein Binding; Protein Processing, Post-Translational; Recombinant Proteins | 2013 |
A new method for quantitative immunoblotting of endogenous α-synuclein.
Topics: alpha-Synuclein; Cell Line; Humans; Immunoblotting; Lysine | 2013 |
Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.
Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Bridged-Ring Compounds; Diffusion; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Organophosphates; Parkinson Disease; Probability; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Treatment Outcome | 2014 |
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.
Topics: alpha-Synuclein; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Lewy Body Disease; Lysine; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Synapses; Thy-1 Antigens | 2014 |
Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.
Topics: alpha-Synuclein; Amino Acid Motifs; Cell Line, Tumor; Endosomal Sorting Complexes Required for Transport; Endosomes; Humans; Lysine; Nedd4 Ubiquitin Protein Ligases; Parkinson Disease; Protein Transport; Ubiquitin-Protein Ligases; Ubiquitination | 2014 |
Interplay between sumoylation and phosphorylation for protection against α-synuclein inclusions.
Topics: alpha-Synuclein; Autophagy; Chromatography, Affinity; G-Protein-Coupled Receptor Kinase 5; Humans; Lewy Bodies; Lysine; Microscopy, Fluorescence; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Sumoylation; Ubiquitin | 2014 |
Differences in the binding of copper(I) to α- and β-synuclein.
Topics: alpha-Synuclein; Amino Acid Sequence; beta-Synuclein; Cations, Monovalent; Chemical Precipitation; Copper; Humans; Lysine; Methionine; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Solid-Phase Synthesis Techniques; Solutions | 2015 |
Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Amyloid; Animals; Cell Membrane; Dopamine; Dopaminergic Neurons; Humans; Lysine; Membrane Lipids; Oxidation-Reduction; Parkinson Disease; Rats; Schiff Bases; Substantia Nigra | 2015 |
Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and Toxicity.
Topics: Acetone; alpha-Synuclein; Lysine; Peptides; Sumoylation; Ubiquitination | 2016 |
Nuclear Magnetic Resonance Observation of α-Synuclein Membrane Interaction by Monitoring the Acetylation Reactivity of Its Lysine Side Chains.
Topics: Acetylation; alpha-Synuclein; Circular Dichroism; Kinetics; Lipid Bilayers; Lysine; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Succinimides | 2016 |
α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses.
Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Cell Line, Tumor; Drosophila melanogaster; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Male; Methylation; Mice; Neuroblastoma; Repressor Proteins; Transcription, Genetic | 2016 |
α-Synuclein structural features inhibit harmful polyunsaturated fatty acid oxidation, suggesting roles in neuroprotection.
Topics: alpha-Synuclein; Arachidonic Acid; Binding Sites; Brain; Circular Dichroism; Docosahexaenoic Acids; Fatty Acids, Unsaturated; Humans; Lipid Metabolism; Lysine; Mass Spectrometry; Methionine; Neuroprotection; Oxygen; Parkinson Disease; Protein Structure, Secondary; Trypsin | 2017 |
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylation; alpha-Synuclein; Animals; Autophagy; Cell Membrane; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dopaminergic Neurons; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Lysine; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neuroprotection; Parkinson Disease; Protein Aggregates; Protein Binding; Sirtuin 2 | 2017 |
Superoxide is the critical driver of DOPAL autoxidation, lysyl adduct formation, and crosslinking of α-synuclein.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Binding Sites; Cross-Linking Reagents; Enzyme Activation; Lysine; Oxidation-Reduction; Oxygen; Protein Binding; Pyrroles; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Cells, Cultured; Chickens; Dopaminergic Neurons; HEK293 Cells; Humans; Lysine; Methionine; Mice; Micrococcus luteus; Microtubule-Associated Proteins; Muramidase; Neuroprotective Agents; Oxidation-Reduction; Peptide Fragments; Protein Aggregation, Pathological; Quinones; Tyrosine 3-Monooxygenase | 2017 |
Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.
Topics: alpha-Synuclein; Animals; Bromodeoxyuridine; Caspase 3; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Gene Expression Regulation; Glutamic Acid; Hippocampus; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurodegenerative Diseases; Neurogenesis; Neurons; Neuropeptides; Phosphopyruvate Hydratase; SOXB1 Transcription Factors | 2018 |
Synergistic Amyloid Switch Triggered by Early Heterotypic Oligomerization of Intrinsically Disordered α-Synuclein and Tau.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid; Humans; Lysine; Models, Molecular; Parkinson Disease; Protein Aggregates; Protein Conformation; Protein Folding; Spectrometry, Fluorescence; tau Proteins | 2018 |
A novel extended form of alpha-synuclein 3'UTR in the human brain.
Topics: 3' Untranslated Regions; alpha-Synuclein; Base Sequence; Brain; Cell Line, Tumor; Histones; Humans; Lysine; RNA-Binding Proteins; RNA, Messenger | 2018 |
Methionine sulfoxide reductase A (MsrA) mediates the ubiquitination of 14-3-3 protein isotypes in brain.
Topics: 14-3-3 Proteins; alpha-Synuclein; Amino Acid Sequence; Animals; Archaeal Proteins; Binding, Competitive; Brain; Brain Chemistry; Dopamine; Lysine; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Knockout; Phosphorylation; Protein Binding; Protein Isoforms; Protein Processing, Post-Translational; Serine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
E46K-like α-synuclein mutants increase lipid interactions and disrupt membrane selectivity.
Topics: alpha-Synuclein; Cell Membrane; Glutamic Acid; Humans; Lipids; Lysine; Mutant Proteins; Mutation | 2019 |
Post-translational modification of lysine residues in erythrocyte α-synuclein.
Topics: alpha-Synuclein; Erythrocytes; Humans; Lysine; Phosphorylation; Protein Processing, Post-Translational | 2023 |