Page last updated: 2024-08-17

lysine and 4-hydroxy-2-nonenal

lysine has been researched along with 4-hydroxy-2-nonenal in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (29.82)	18.2507
2000's	24 (42.11)	29.6817
2010's	14 (24.56)	24.3611
2020's	2 (3.51)	2.80

Authors

Authors	Studies
Chojkier, M; Filip, M; Houglum, K; Witztum, JL	1
Ibovnik, A; Kostner, GM; Leis, HJ; Malle, E; Sattler, W; Verhallen, PF	1
Nadkarni, DV; Sayre, LM	1
Hiai, H; Kawakishi, S; Nishikawa, K; Oda, H; Stadtman, ER; Toyokuni, S; Uchida, K	1
Davis, P; Exner, M; Kerjaschki, D; Neale, TJ; Ojha, PP; Poczewski, H; Rüger, B; Witztum, JL	1
Stadtman, ER; Uchida, K	1
Stadtman, ER; Szweda, LI; Tsai, L; Uchida, K	1
Cohn, JA; Friguet, B; Szweda, LI; Tsai, L	1
Ahmed, MU; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR	1
Ahmed, MU; Baynes, JW; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR	1
Brannian, JD; Burbach, JA; Zhao, Y	1
Angelini, G; Dagna-Bricarelli, F; Dapino, D; Garibaldi, S; Odetti, P; Perry, G; Piombo, G; Smith, M; Tabaton, M; Traverso, N; Zaccheo, D	1
Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N	1
Szweda, LI; Szweda, PA; Tsai, L; Vinogradova, O	1
Kansal, MM; Liu, Y; Sayre, LM; Xu, G	1
Sayre, LM; Xu, G	1
Uchida, K	1
Liu, Y; Sayre, LM; Xu, G	1
Fujita, Y; Hirano, H; Horie, K; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Uchida, K; Ueda, Y; van Ypersele de Strihou, C	1
Angelini, G; Garibaldi, S; Marinelli, L; Menini, S; Norese, R; Odetti, P; Perry, G; Siedlak, S; Smith, MA; Tabaton, M; Traverso, N; Valentini, S; Zaccheo, D	1
Asayama, K; Hirano, A; Horiuchi, S; Jono, T; Kato, S; Kobayashi, M; Miyata, S; Nagai, R; Sasaki, S; Shibata, N	1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C	1
Sloop, GD	1
Szweda, LI; Szweda, PA; Tsai, L	1
Doorn, JA; Petersen, DR	1
Hoff, HF; Hoppe, G; O'Neil, J; Salomon, RL; Wu, Z	1
Castellani, RJ; Ghanbari, HA; Ghanbari, K; Harris, PL; Jones, PK; Kubat, Z; Perry, G; Smith, MA; Wolozin, BL	1
Barnes, S; Coward, L; Darley-Usmar, V; Isom, AL; Kirk, M; Wilson, L	1
Amadio, L; Di Mario, U; Iacobini, C; Menini, S; Oddi, G; Olivieri, A; Pesce, C; Pricci, F; Pugliese, G; Ricci, C; Sorcini, M	1
Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W	1
Amadio, L; Di Pippo, C; Iacobini, C; Menini, S; Oddi, G; Pricci, F; Pugliese, F; Pugliese, G; Ricci, C; Sorcini, M	1
Akatsuka, S; Lee, WH; Miyagawa-Hayashino, A; Ozeki, M; Shirase, T; Toyokuni, S; Uchida, K	1
Lee, HG; Lin, D; Liu, Q; Perry, G; Sayre, LM; Smith, MA	1
Cottalasso, D; Furfaro, AL; Marinari, UM; Menini, S; Odetti, P; Patriarca, S; Pesce, C; Pronzato, MA; Traverso, N	1
Aiuchi, T; Itabe, H; Kato, R; Masuda, Y; Obama, T; Takahashi, K	1
Doorn, JA; Petersen, DR; Stewart, BJ	1
Calabrese, V; Calafato, S; Castellino, P; Cornelius, C; Di Mauro, M; Finocchiaro, M; Mancuso, C; Mangiameli, A; Puleo, E; Sapienza, M; Stella, AM	1
Aldini, G; Carini, M; Facino, RM; Gamberoni, L; Regazzoni, L; Uchida, K; Vistoli, G; Yamaguchi, S	1
Annangudi, SP; Crabb, JW; Deng, Y; Gu, X; Salomon, RG; Zhang, W	1
Andrew, R; Ellis, E; Pournamdari, M; Saadi, A; Walker, B; Watson, DG	1
Busseuil, D; Comte, B; Frayne, IR; Lesgards, JF; Rhéaume, E; Rosiers, CD; Tardif, JC	1
Bautista, JM; Diez, A; Hernaez, ML; Mendez, D; Puyet, A	1
Backos, DS; Franklin, CC; Fritz, KS; Petersen, DR; Roede, JR	1
Ayako, I; Dogru, M; Fujishima, H; Fukagawa, K; Ibrahim, OM; Matsumoto, Y; Okada, N; Satake, Y; Shimazaki, J; Takano, Y; Tsubota, K; Wakamatsu, TH	1
Benderdour, M; Bentz, M; Fahmi, H; Fernandes, JC; Moldovan, F; Shi, Q; Zaouter, C	1
Gronert, S; Liu, Q; Simpson, DC	1
Chen, J; Xiong, YL; Zhao, J; Zhu, H	1
Dogru, M; Ibrahim, OM; Ichihashi, Y; Igarashi, A; Kaido, M; Kojima, T; Matsumoto, Y; Satake, Y; Sato, EA; Shimazaki, J; Tsubota, K; Wakamatsu, TH	1
Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J	1
Castellani, RJ; Harris, PL; Lui, Q; Moreira, PI; Nunomura, A; Perry, EA; Perry, G; Sayre, LM; Smith, MA; Szweda, LI; Szweda, PA; Zhu, X	1
Handa, O; Naito, Y; Takagi, T; Yoshikawa, T	1
Globisch, M; Henle, T; Kaden, D	1
Bubacco, L; Plotegher, N	1
Forman, HJ; Zhang, H	1
Abe, K; Fukui, Y; Hishikawa, N; Inufusa, H; Kusaki, M; Liu, X; Morihara, R; Nakano, Y; Ohta, Y; Sato, K; Shang, J; Takemoto, M; Tian, F; Yamashita, T	1
Abe, K; Bian, Y; Hishikawa, N; Matsumoto, N; Nomura, E; Ohta, Y; Omote, Y; Sasaki, R; Shang, J; Tadokoro, K; Taira, Y; Takemoto, M; Tsunoda, K; Yamashita, T	1
Fiser, B; Olasz, B; Owen, MC; Szőri, M; Viskolcz, B	1

Reviews

5 review(s) available for lysine and 4-hydroxy-2-nonenal

Article	Year
Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5 Topics: Aldehydes; Arteriosclerosis; Biomarkers; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Maillard Reaction; Malondialdehyde; Oxidative Stress; Proteins	1996
Current status of acrolein as a lipid peroxidation product. Trends in cardiovascular medicine, 1999, Volume: 9, Issue:5 Topics: Acrolein; Air Pollutants; Aldehydes; Alzheimer Disease; Arteriosclerosis; Cross-Linking Reagents; Fatty Acids, Unsaturated; Glyoxal; Humans; Lipid Peroxidation; Lipid Peroxides; Lysine; Malondialdehyde; Oxidative Stress	1999
Lipid hydroperoxide-derived modification of proteins in gastrointestinal tract. Sub-cellular biochemistry, 2014, Volume: 77 Topics: Aldehydes; Biomarkers; Gastrointestinal Tract; Hexanols; Humans; Lipid Peroxidation; Lipid Peroxides; Lysine; Oxidative Stress; Proteins	2014
Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin. Ageing research reviews, 2016, Volume: 26 Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehydes; alpha-Synuclein; Brain; Dopamine; Humans; Lysine; Metabolism; Neurodegenerative Diseases; Neurons	2016
Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation. Archives of biochemistry and biophysics, 2017, Mar-01, Volume: 617 Topics: Aldehydes; Animals; Autophagy; Cysteine; Histidine; Humans; Lipid Peroxidation; Lysine; Lysosomes; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Signal Transduction	2017

Other Studies

52 other study(ies) available for lysine and 4-hydroxy-2-nonenal

Article	Year
Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload. The Journal of clinical investigation, 1990, Volume: 86, Issue:6 Topics: Aldehydes; Animals; Body Weight; Electrophoresis, Gel, Two-Dimensional; Fluorescence; Iron; Lipid Peroxides; Liver; Lysine; Male; Malondialdehyde; Molecular Weight; Proteins; Rats; Rats, Inbred Strains; Thiobarbiturates	1990
Lysine modification of LDL or lipoprotein(a) by 4-hydroxynonenal or malondialdehyde decreases platelet serotonin secretion without affecting platelet aggregability and eicosanoid formation. Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:3 Topics: Acetylation; Aldehydes; Blood Platelets; Eicosanoids; Gas Chromatography-Mass Spectrometry; Humans; Lipoprotein(a); Lipoproteins, LDL; Lysine; Malondialdehyde; Platelet Aggregation; Serotonin	1995
Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal. Chemical research in toxicology, 1995, Volume: 8, Issue:2 Topics: Aldehydes; Cross-Linking Reagents; Histidine; Lysine; Magnetic Resonance Spectroscopy; Molecular Structure; Schiff Bases	1995
Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis. Biochemistry, 1994, Oct-18, Volume: 33, Issue:41 Topics: Aldehydes; Animals; Antibodies; Aorta; Apolipoprotein B-100; Apolipoproteins B; Arteriosclerosis; Binding, Competitive; Cattle; Cells, Cultured; Copper; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Immunoblotting; Lipoproteins, LDL; Lysine; Malondialdehyde; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances	1994
Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen. The Journal of clinical investigation, 1994, Volume: 94, Issue:4 Topics: Aldehydes; Animals; Anticholesteremic Agents; Antigen-Antibody Complex; Basement Membrane; Cholesterol; Collagen; Disease Models, Animal; Epithelial Cells; Glomerulonephritis; Kidney Glomerulus; Lipid Peroxidation; Lovastatin; Lysine; Male; Malondialdehyde; Probucol; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Simvastatin	1994
Quantitation of 4-hydroxynonenal protein adducts. Methods in enzymology, 1994, Volume: 233 Topics: Acetylcysteine; Aldehydes; Chromatography, High Pressure Liquid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Indicators and Reagents; Lipid Peroxidation; Lysine; Protein Binding; Proteins; Radioisotope Dilution Technique; Tritium	1994
Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine. The Journal of biological chemistry, 1993, Feb-15, Volume: 268, Issue:5 Topics: Aldehydes; Amino Acids; Binding Sites; Glucosephosphate Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; Leuconostoc; Lysine; Phenylhydrazines	1993
Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress. Archives of biochemistry and biophysics, 1996, Apr-01, Volume: 328, Issue:1 Topics: Aldehydes; Animals; Cross-Linking Reagents; Glucosephosphate Dehydrogenase; Histidine; Immunochemistry; Lipid Peroxidation; Lysine; Male; Mitochondria, Liver; Models, Chemical; Oxidative Stress; Proteins; Rats; Rats, Inbred F344; Schiff Bases	1996
Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein. The Biochemical journal, 1997, Feb-15, Volume: 322 ( Pt 1) Topics: Aldehydes; Amino Acids; Collagen; Copper; Crystallins; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Malondialdehyde; Oxidation-Reduction; Ribonucleases; Schiff Bases; Skin	1997
Localization of lipid peroxidation-derived protein epitopes in the porcine corpus luteum. Biology of reproduction, 1997, Volume: 57, Issue:6 Topics: Aldehydes; Animals; Antibodies, Monoclonal; Corpus Luteum; Epitopes; Estrus; Female; Humans; Immunoblotting; Immunohistochemistry; Lipid Peroxidation; Lysine; Malondialdehyde; Mice; Swine	1997
Early glycoxidation damage in brains from Down's syndrome. Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3 Topics: Aldehydes; Amyloid beta-Protein Precursor; Arginine; Brain; Cerebral Cortex; Down Syndrome; Gestational Age; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lysine; Norleucine; Oxidation-Reduction; Oxidative Stress; Pyrroles; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	1998
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage. Atherosclerosis, 1998, Volume: 136, Issue:2 Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin	1998
Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine. Proceedings of the National Academy of Sciences of the United States of America, 1998, Jul-07, Volume: 95, Issue:14 Topics: Aldehydes; Animals; Cross-Linking Reagents; Female; Fluorescent Dyes; Immunization; Immunoassay; Lysine; Rabbits	1998
Rapid cross-linking of proteins by 4-ketoaldehydes and 4-hydroxy-2-alkenals does not arise from the lysine-derived monoalkylpyrroles. Chemical research in toxicology, 1999, Volume: 12, Issue:9 Topics: Aldehydes; Animals; Cattle; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanones; Lysine; Proteins; Pyrroles; Ribonuclease, Pancreatic; Schiff Bases; Serum Albumin, Bovine	1999
Structural elucidation of a 2:2 4-ketoaldehyde-amine adduct as a model for lysine-directed cross-linking of proteins by 4-ketoaldehydes. Chemical research in toxicology, 1999, Volume: 12, Issue:9 Topics: Aldehydes; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; Lysine; Methylamines; Models, Chemical; Molecular Conformation; Molecular Structure; Pyrroles; Schiff Bases	1999
Polyclonal antibodies to a fluorescent 4-hydroxy-2-nonenal (HNE)-derived lysine-lysine cross-link: characterization and application to HNE-treated protein and in vitro oxidized low-density lipoprotein. Chemical research in toxicology, 2000, Volume: 13, Issue:5 Topics: Aldehydes; Animals; Cattle; Chromatography, High Pressure Liquid; Copper; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Epitopes; Fluorescence; Fluorescent Dyes; Immunoglobulin G; In Vitro Techniques; Lipoproteins, LDL; Lysine; Oxidation-Reduction; Rabbits; Serum Albumin, Bovine	2000
Advanced glycation and lipidoxidation of the peritoneal membrane: respective roles of serum and peritoneal fluid reactive carbonyl compounds. Kidney international, 2000, Volume: 58, Issue:1 Topics: Adult; Aged; Aldehydes; Arginine; Ascitic Fluid; Dialysis Solutions; Filtration; Glucose; Glycation End Products, Advanced; Hot Temperature; Humans; Kidney Failure, Chronic; Lipid Peroxidation; Lysine; Middle Aged; Peritoneal Dialysis; Peritoneum; Sterilization; Uremia	2000
Lipoperoxidation is selectively involved in progressive supranuclear palsy. Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:5 Topics: Aged; Aldehydes; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxides; Lysine; Mesencephalon; Middle Aged; Norleucine; Pyrroles; Reference Values; Supranuclear Palsy, Progressive; tau Proteins; Thiobarbituric Acid Reactive Substances	2000
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta neuropathologica, 2000, Volume: 100, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Aged; Aldehydes; Amyotrophic Lateral Sclerosis; Arginine; Deoxyguanosine; Glycosylation; Humans; Imidazoles; Lipid Peroxidation; Lysine; Male; Middle Aged; Motor Neurons; Oxidative Stress; Spinal Cord; Superoxide Dismutase	2000
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation. Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9 Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines	2000
Localization of oxidation-specific epitopes in tissue. Methods in enzymology, 2002, Volume: 352 Topics: Aldehydes; Animals; Apoptosis; Cross-Linking Reagents; Disease Models, Animal; Epitopes; Humans; Immunohistochemistry; Lysine; Malondialdehyde; Oxygen; Rabbits	2002
Immunochemical detection of a fluorophore derived from the lipid peroxidation product 4-hydroxy-2-nonenal and lysine. Methods in molecular biology (Clifton, N.J.), 2002, Volume: 196 Topics: Aldehydes; Binding, Competitive; Blotting, Western; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Glucosephosphate Dehydrogenase; Immunohistochemistry; Indicators and Reagents; Leuconostoc; Lipid Peroxidation; Lysine	2002
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal. Chemical research in toxicology, 2002, Volume: 15, Issue:11 Topics: Aldehydes; Amino Acids; Arginine; Cysteine; Histidine; Kinetics; Lipid Peroxidation; Lysine; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity	2002
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions. Arteriosclerosis, thrombosis, and vascular biology, 2003, Feb-01, Volume: 23, Issue:2 Topics: Acetylcysteine; Aldehydes; Animals; Arteriosclerosis; Biological Transport; Cathepsin B; Cholesterol Esters; Chromatography, Liquid; Humans; Intracellular Membranes; Lipoproteins, LDL; Lysine; Lysosomes; Macrophages, Peritoneal; Mice; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2003
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging cell, 2004, Volume: 3, Issue:1 Topics: Aldehydes; Alzheimer Disease; Cell Line; Cells, Cultured; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Membrane Proteins; Neurons; Olfactory Mucosa; Oxidative Stress	2004
Modification of Cytochrome c by 4-hydroxy- 2-nonenal: evidence for histidine, lysine, and arginine-aldehyde adducts. Journal of the American Society for Mass Spectrometry, 2004, Volume: 15, Issue:8 Topics: Aldehydes; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cross-Linking Reagents; Cytochromes c; Histidine; Horses; Lysine; Molecular Sequence Data; Myocardium; Peptide Mapping; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2004
Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:14 Topics: Aldehydes; Animals; Cell Death; Cell Proliferation; Extracellular Matrix Proteins; Galectin 3; Glycation End Products, Advanced; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kinetics; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta	2004
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress. Stroke, 2005, Volume: 36, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis	2005
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:3 Topics: Age Factors; Aging; Aldehydes; Animals; Body Weight; Dinoprost; Extracellular Matrix; Galectin 3; Glomerulonephritis; Glycation End Products, Advanced; Kidney Glomerulus; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Susceptibility of actin to modification by 4-hydroxy-2-nonenal. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Nov-15, Volume: 827, Issue:1 Topics: Actins; Albumins; Aldehydes; Animals; Antibodies, Monoclonal; Blotting, Western; Cysteine; Ferric Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Histidine; Kidney; Kidney Neoplasms; Lysine; Male; Metallothionein; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Superoxide Dismutase	2005
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chemical research in toxicology, 2005, Volume: 18, Issue:8 Topics: Aldehydes; Butylamines; Cell Line; Cell Survival; Cysteine; Cysteine Proteinase Inhibitors; Histidine; Humans; Immunohistochemistry; Indicators and Reagents; Kinetics; Lysine; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Proteins; Schiff Bases; Spectrophotometry, Ultraviolet	2005
HNE-dependent molecular damage in diabetic nephropathy and its possible prevention by N-acetyl-cysteine and oxerutin. BioFactors (Oxford, England), 2005, Volume: 24, Issue:1-4 Topics: Acetylcysteine; Aldehydes; Animals; Apoptosis; Cell Division; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Rats; Rats, Wistar; Taurine	2005
Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS. Proteomics, 2007, Volume: 7, Issue:13 Topics: Acrolein; Aldehydes; Amino Acid Sequence; Apolipoprotein B-100; Chloroform; Chromatography, Liquid; Copper Sulfate; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Kynurenine; Lipoproteins, LDL; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Polyvinyls; Tandem Mass Spectrometry; Trypsin; Tryptophan	2007
Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerization. Chemical research in toxicology, 2007, Volume: 20, Issue:8 Topics: Aldehydes; Animals; Brain; Cattle; Cross-Linking Reagents; Cysteine; Electrophoresis, Gel, Two-Dimensional; Lysine; Mass Spectrometry; Oxidative Stress; Polymers; Tubulin	2007
Oxidative stress and cellular stress response in diabetic nephropathy. Cell stress & chaperones, 2007,Winter, Volume: 12, Issue:4 Topics: Aldehydes; Arginine; Chaperonin 60; Diabetic Nephropathies; F2-Isoprostanes; Female; Heat-Shock Response; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Humans; Lymphocytes; Lysine; Male; Middle Aged; Oxidative Stress; Protein Carbonylation; Renal Insufficiency; Thioredoxin Reductase 1	2007
Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species? Chemical research in toxicology, 2008, Volume: 21, Issue:4 Topics: Adult; Aldehydes; Atherosclerosis; Cysteine; Humans; Lysine; Peptides; Protective Agents; Serum Albumin	2008
Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE. Chemical research in toxicology, 2008, Volume: 21, Issue:7 Topics: Acetylcysteine; Aldehydes; Cross-Linking Reagents; Histidine; Lipoproteins, LDL; Lysine; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors	2008
Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry. Analytica chimica acta, 2009, Feb-09, Volume: 633, Issue:2 Topics: Aldehydes; Amino Acids; Animals; Blood Proteins; Chromatography, Liquid; Fourier Analysis; Histidine; Humans; Lysine; Mass Spectrometry; Piperidines; Pyridinium Compounds; Schiff Bases; Serum Albumin, Bovine	2009
Differential distribution of 4-hydroxynonenal adducts to sulfur and nitrogen residues in blood proteins as revealed using Raney nickel and gas chromatography-mass spectrometry. Free radical biology & medicine, 2009, Nov-15, Volume: 47, Issue:10 Topics: Aldehydes; Animals; Blood Proteins; Gas Chromatography-Mass Spectrometry; Histidine; Lysine; Male; Nickel; Rabbits	2009
Combined proteomic approaches for the identification of specific amino acid residues modified by 4-hydroxy-2-nonenal under physiological conditions. Journal of proteome research, 2010, Nov-05, Volume: 9, Issue:11 Topics: Aldehydes; Amino Acids; Animals; Biomarkers; Cattle; Erythrocyte Membrane; Histidine; Humans; Lysine; Membrane Proteins; Oxidative Stress; Protein Processing, Post-Translational; Proteomics; Serum Albumin, Bovine; Spectrin	2010
Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal. Free radical biology & medicine, 2011, Jan-01, Volume: 50, Issue:1 Topics: Aldehydes; Animals; Cysteine; Cysteine Proteinase Inhibitors; Glutamate-Cysteine Ligase; Humans; Lipid Peroxidation; Lysine; Mass Spectrometry; Metabolic Detoxication, Phase I; Mice; Oxidative Stress; Protein Processing, Post-Translational; Protein Subunits; Stereoisomerism; Tumor Cells, Cultured	2011
Evaluation of lipid oxidative stress status and inflammation in atopic ocular surface disease. Molecular vision, 2010, Nov-19, Volume: 16 Topics: Adolescent; Adult; Aldehydes; Biomarkers; Case-Control Studies; Cell Count; Child; Conjunctiva; Conjunctivitis, Allergic; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophils; Epithelium, Corneal; Female; Humans; Immunohistochemistry; Inflammation; Lipid Metabolism; Lysine; Male; Oxidative Stress; Staining and Labeling; Tears; Young Adult	2010
Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes. Journal of cellular biochemistry, 2012, Volume: 113, Issue:7 Topics: Aldehydes; Apoptosis; Cells, Cultured; Chondrocytes; Dinoprostone; Glutathione Transferase; Humans; Inflammation; Interleukin-1beta; Lipid Peroxidation; Lysine; Matrix Metalloproteinase 13; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Oxidative Stress; Reactive Oxygen Species	2012
The reactivity of human serum albumin toward trans-4-hydroxy-2-nonenal. Journal of mass spectrometry : JMS, 2012, Volume: 47, Issue:4 Topics: Aldehydes; Amino Acid Sequence; Cysteine; Histidine; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Serum Albumin; Thermodynamics	2012
Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides. Journal of agricultural and food chemistry, 2012, Sep-26, Volume: 60, Issue:38 Topics: Aldehydes; Amino Acids; Chromatography, Liquid; Cross-Linking Reagents; Free Radical Scavengers; Lysine; Malondialdehyde; Schiff Bases; Soybean Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2012
Evaluation of lipid oxidative stress status in Sjögren syndrome patients. Investigative ophthalmology & visual science, 2013, Jan-07, Volume: 54, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Aldehydes; Biomarkers; Conjunctiva; Female; Humans; Inflammation; Lipid Peroxidation; Lysine; Male; Middle Aged; Oxidative Stress; Prospective Studies; Reactive Oxygen Species; Sjogren's Syndrome; Tears	2013
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes. Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2 Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels	2013
Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free radical research, 2013, Volume: 47, Issue:6-7 Topics: Aldehydes; Animals; Antibodies; Fluorescence; Lysine; Mice; Mice, Inbred Strains; Neurofilament Proteins; Sciatic Nerve	2013
4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts. Journal of agricultural and food chemistry, 2015, Jun-03, Volume: 63, Issue:21 Topics: Aldehydes; Arachis; Cooking; Hot Temperature; Lipids; Lysine; Molecular Structure; Peanut Oil; Plant Oils; Pyrroles	2015
Neuroprotective Effects of a Novel Antioxidant Mixture Twendee X in Mouse Stroke Model. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Brain; Deoxyguanosine; Disease Models, Animal; Glycation End Products, Advanced; Infarction, Middle Cerebral Artery; Inflammation Mediators; Lysine; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Time Factors	2017
Antioxidative effects of a novel dietary supplement Neumentix in a mouse stroke model. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antioxidants; Brain; Cinnamates; Depsides; Dietary Supplements; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lysine; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Rosmarinic Acid	2020
Computational Elucidation of the Solvent-Dependent Addition of 4-Hydroxy-2-nonenal (HNE) to Cysteine and Cysteinate Residues. The Journal of organic chemistry, 2022, 10-07, Volume: 87, Issue:19 Topics: Aldehydes; Amino Acids; Antioxidants; Cysteine; Histidine; Lipid Peroxidation; Lysine; Oxidative Stress; Solvents; Water	2022