Compounds > lysergic acid diethylamide
Page last updated: 2024-08-17

lysergic acid diethylamide and mdl 100907

lysergic acid diethylamide has been researched along with mdl 100907 in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.71)18.2507
2000's13 (46.43)29.6817
2010's8 (28.57)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Carlsson, ML1
Aghajanian, GK; Marek, GJ1
Geyer, MA; Krebs-Thomson, K; Paulus, MP1
Barrett, RJ; Sanders-Bush, E; Smith, RL1
Dwivedi, Y; Janicak, PG; Pandey, GN; Pandey, SC; Ren, X1
Nichols, CD; Sanders-Bush, E1
Hull, EM; Muschamp, JW; Rabin, RA; Regina, MJ; Winter, JC1
Barrett, RJ; Benneyworth, MA; Sanders-Bush, E; Smith, RL1
Marona-Lewicka, D; Nichols, DE; Thisted, RA1
Barrett, RJ; Gresch, PJ; Sanders-Bush, E; Smith, RL2
Eckler, JR; Kieres, AK; Rabin, RA; Reissig, CJ; Rice, KC; Richards, JB; Ullrich, T; Winter, JC; Zimmerman, MD1
Coop, A; Eckler, JR; Fantegrossi, WE; Harrington, AW; Kiessel, CL; Rabin, RA; Rice, KC; Winter, JC; Woods, JH1
Fantegrossi, WE; Katz, EB; Reissig, CJ; Rice, KC; Winter, JC; Yarosh, HL1
Eckler, JR; Rabin, RA; Reissig, CJ; Rice, KC; Winter, JC1
Benneyworth, MA; Sanders-Bush, E; Smith, RL1
Geyer, MA; Halberstadt, AL1
Foley, JJ; Walker, EA1
Agnati, LF; Borroto-Escuela, DO; Fuxe, K; Narvaez, M; Oflijan, J; Romero-Fernandez, W1
Kraehenmann, R; Pokorny, D; Pokorny, T; Preller, KH; Seifritz, E; Vollenweider, FX; Vollenweider, L1
Barrett, FS; Herdener, M; Janata, P; Preller, KH; Vollenweider, FX1
Jalal, B1
Adkinson, BD; Anticevic, A; Burt, JB; Ji, JL; Krystal, JH; Murray, JD; Preller, KH; Repovs, G; Schleifer, CH; Seifritz, E; Stämpfli, P; Vollenweider, FX1
Bowen, JP; Daphney, CM; Guner, OF; Moniri, NH; Murnane, KS; Murphy, TJ; Oppong-Damoah, A; Rambacher, KM; Rice, KC1
Domenico, C; Haggerty, D; Ji, D; Mou, X1
de la Fuente Revenga, M; Elder, H; González-Maeso, J; Jaster, AM; Marsh, SA; Negus, SS1
Abizaid, A; Aguilar-Valles, A; Arsenault, E; Bautista-Carro, MA; Bonniwell, EM; Calkins, MM; Cao, AB; El Sayegh, F; Ghaffari, A; Halberstadt, AL; Lanham, JK; Lewis, V; Malcolm, NJ; McCorvy, JD; Morton, K; Schmid, Y; Sheshbaradaran, H; Taghavi-Abkuh, FF; Telfer, A1
O'Grady, C1

Reviews

1 review(s) available for lysergic acid diethylamide and mdl 100907

ArticleYear
The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug.
    Psychopharmacology, 2018, Volume: 235, Issue:11

    Topics: Animals; Dopamine; Hallucinations; Hallucinogens; Humans; Lysergic Acid Diethylamide; Neuropharmacology; Piperidines; Psilocybin; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sleep; Sleep Paralysis; Urea

2018

Trials

1 trial(s) available for lysergic acid diethylamide and mdl 100907

ArticleYear
Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor.
    eLife, 2018, 10-25, Volume: 7

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Hallucinogens; Healthy Volunteers; Humans; Lysergic Acid Diethylamide; Male; Neural Pathways; Placebos; Serotonin 5-HT2 Receptor Antagonists; Thalamus; Young Adult

2018

Other Studies

26 other study(ies) available for lysergic acid diethylamide and mdl 100907

ArticleYear
The selective 5-HT2A receptor antagonist MDL 100,907 counteracts the psychomotor stimulation ensuing manipulations with monoaminergic, glutamatergic or muscarinic neurotransmission in the mouse--implications for psychosis.
    Journal of neural transmission. General section, 1995, Volume: 100, Issue:3

    Topics: Animals; Biogenic Monoamines; Disease Models, Animal; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Piperazines; Piperidines; Psychomotor Performance; Psychotic Disorders; Receptor, Serotonin, 5-HT2A; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1995
LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; In Vitro Techniques; Interneurons; Lysergic Acid Diethylamide; Male; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Effects of hallucinogens on locomotor and investigatory activity and patterns: influence of 5-HT2A and 5-HT2C receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:5

    Topics: Amphetamines; Animals; Exploratory Behavior; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1998
Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice.
    Psychopharmacology, 2003, Volume: 166, Issue:1

    Topics: Aminopyridines; Animals; Conditioning, Operant; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Indophenol; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Piperazines; Piperidines; Pyridines; Reaction Time; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Serotonin receptors in platelets of bipolar and schizoaffective patients: effect of lithium treatment.
    Psychopharmacology, 2003, Volume: 170, Issue:2

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Binding Sites; Bipolar Disorder; Blood Platelets; Drug Therapy, Combination; Female; Humans; Iodine Isotopes; Lithium; Lysergic Acid Diethylamide; Male; Psychotic Disorders; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Suicide, Attempted; Tissue Distribution

2003
Molecular genetic responses to lysergic acid diethylamide include transcriptional activation of MAP kinase phosphatase-1, C/EBP-beta and ILAD-1, a novel gene with homology to arrestins.
    Journal of neurochemistry, 2004, Volume: 90, Issue:3

    Topics: Animals; Arrestins; CCAAT-Enhancer-Binding Protein-beta; Cell Cycle Proteins; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Gene Expression; Gene Expression Profiling; Hallucinogens; Immediate-Early Proteins; Lysergic Acid Diethylamide; Male; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Prefrontal Cortex; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Time Factors; Transcriptional Activation

2004
Lysergic acid diethylamide and [-]-2,5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex.
    Brain research, 2004, Oct-08, Volume: 1023, Issue:1

    Topics: Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Extracellular Fluid; Glutamic Acid; Lysergic Acid Diethylamide; Male; Prefrontal Cortex; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2004
Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice.
    Psychopharmacology, 2005, Volume: 179, Issue:4

    Topics: Animals; Cues; Discrimination Learning; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Fluorobenzenes; Food; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Piperidines; Receptor, Serotonin, 5-HT2A; Reinforcement Schedule; Reinforcement, Psychology; Serotonin Antagonists

2005
Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis.
    Psychopharmacology, 2005, Volume: 180, Issue:3

    Topics: Amphetamine; Amphetamines; Animals; Apomorphine; Behavior, Animal; Cues; Discrimination Learning; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Haloperidol; Indans; Injections, Intraperitoneal; Lysergic Acid Diethylamide; Male; Piperidines; Psychotic Disorders; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2005
Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:9

    Topics: Amphetamines; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Cerebral Cortex; Diagnostic Imaging; Drug Interactions; Drug Tolerance; Fluorobenzenes; Guanosine 5'-O-(3-Thiotriphosphate); Hallucinogens; Indoles; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Piperidines; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Signal Transduction; Sulfur Isotopes; Time Factors

2005
The stimulus properties of LSD in C57BL/6 mice.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:4

    Topics: Animals; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Piperidines; Rats; Serotonin Antagonists; Time Factors

2005
Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Brain; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists

2006
5-Hydroxytryptamine (serotonin)2A receptors in rat anterior cingulate cortex mediate the discriminative stimulus properties of d-lysergic acid diethylamide.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fluorobenzenes; Gyrus Cinguli; Lysergic Acid Diethylamide; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A

2007
Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:3

    Topics: Animals; Data Interpretation, Statistical; Discrimination Learning; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Piperidines; Psilocybin; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Tryptamines

2008
The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluorobenzenes; Lysergic Acid Diethylamide; Male; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Chronic phenethylamine hallucinogen treatment alters behavioral sensitivity to a metabotropic glutamate 2/3 receptor agonist.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:9

    Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Operant; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Fluorobenzenes; Hallucinogens; Locomotion; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred ICR; Phenethylamines; Piperidines; Psychotropic Drugs; Time Factors

2008
LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.
    Psychopharmacology, 2010, Volume: 208, Issue:2

    Topics: Acoustic Stimulation; Animals; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Hallucinogens; Lisuride; Lysergic Acid Diethylamide; Male; Piperazines; Piperidines; Pyridines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reflex, Startle; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2010
Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure.
    Behavioural pharmacology, 2010, Volume: 21, Issue:2

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Inverse Agonism; Drug Partial Agonism; Indoles; Ligands; Lysergic Acid Diethylamide; Male; Memory; Methysergide; Mianserin; Mice; Piperazines; Pyrazines; Pyridines; Reinforcement Schedule; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2010
Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes.
    Biochemical and biophysical research communications, 2014, Jan-03, Volume: 443, Issue:1

    Topics: Amphetamines; Animals; Basal Ganglia; Gene Expression Regulation; Genes, Reporter; Hallucinogens; HEK293 Cells; Humans; Ketanserin; Luciferases; Lysergic Acid Diethylamide; Male; Promoter Regions, Genetic; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2014
Dreamlike effects of LSD on waking imagery in humans depend on serotonin 2A receptor activation.
    Psychopharmacology, 2017, Volume: 234, Issue:13

    Topics: Dopamine; Healthy Volunteers; Humans; Ketanserin; Lysergic Acid Diethylamide; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin 5-HT2 Receptor Antagonists

2017
Serotonin 2A Receptor Signaling Underlies LSD-induced Alteration of the Neural Response to Dynamic Changes in Music.
    Cerebral cortex (New York, N.Y. : 1991), 2018, 11-01, Volume: 28, Issue:11

    Topics: Auditory Perception; Brain; Brain Mapping; Double-Blind Method; Emotions; Hallucinogens; Humans; Ketanserin; Lysergic Acid Diethylamide; Magnetic Resonance Imaging; Memory; Music; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists

2018
The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 181

    Topics: Adrenergic Antagonists; Amphetamines; Animals; Behavior, Animal; Binding Sites; Carvedilol; Computational Chemistry; Drug Discovery; Fluorobenzenes; HEK293 Cells; Humans; Lysergic Acid Diethylamide; Male; Mice; Models, Animal; Models, Molecular; Piperidines; Protein Binding; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Transfection

2019
LSD degrades hippocampal spatial representations and suppresses hippocampal-visual cortical interactions.
    Cell reports, 2021, 09-14, Volume: 36, Issue:11

    Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Electromyography; Fluorobenzenes; Hippocampus; Lysergic Acid Diethylamide; Male; Neurons; Piperidines; Rats; Rats, Long-Evans; Sleep; Visual Cortex; Wakefulness

2021
Effects of the 5-HT
    Psychopharmacology, 2022, Volume: 239, Issue:6

    Topics: Animals; Depression; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Mescaline; Mice; Phenethylamines; Piperidines; Psilocybin; Rats; Receptor, Serotonin, 5-HT2A; Rodentia; Self Stimulation; Serotonin; Tryptamines

2022
A non-hallucinogenic LSD analog with therapeutic potential for mood disorders.
    Cell reports, 2023, 03-28, Volume: 42, Issue:3

    Topics: Animals; Hallucinogens; Lysergic Acid Diethylamide; Mice; Piperidines; Rats; Serotonin

2023
No trip needed for psychedelics to lift mood?
    Science (New York, N.Y.), 2023, 06-09, Volume: 380, Issue:6649

    Topics: Animals; Antidepressive Agents; Brain; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mice; Psilocybin; Receptor, Serotonin, 5-HT2A; Receptor, trkB; Serotonin 5-HT2 Receptor Antagonists

2023