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lysergic acid diethylamide and 4-iodo-2,5-dimethoxyphenylisopropylamine

lysergic acid diethylamide has been researched along with 4-iodo-2,5-dimethoxyphenylisopropylamine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.63)18.7374
1990's20 (46.51)18.2507
2000's12 (27.91)29.6817
2010's6 (13.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartyzel, P; Glennon, RA; Leonhardt, S; Raghupathi, R; Teitler, M1
Kurrasch, D; Marona-Lewicka, D; Nichols, DE; Parker, MA; Shulgin, AT1
Lucaites, VL; Marona-Lewicka, D; Nelson, DL; Nichols, DE; Parker, MA1
Blair, JB; Kanthasamy, A; Lucaites, VL; Marona-Lewicka, D; Nelson, DL; Nichols, DE1
Gerasimov, M; Kurrasch-Orbaugh, DM; Marona-Lewicka, D; Nichols, DE; Qandil, AM1
Dupre, A; Egan, C; Grinde, E; Hake, M; Herrick-Davis, K; Roth, BL; Teitler, M1
Barker, EL; Blair, JB; Cumbay, MG; Kurrasch-Orbaugh, D; Marona-Lewicka, D; Nichols, DE; Watts, VJ1
Kurrasch-Orbaugh, D; Laban, U; Marona-Lewicka, D; Nichols, DE1
Glennon, RA1
Chemel, BR; Frescas, SP; Lewin, AH; Nichols, DE; Rehder, KS; Zhong, D1
Geyer, MA; Mittman, SM1
Himeno, A; Saavedra, JM2
Bickhardt, K; Fredow, G; Ganter, M; Löscher, W; Witte, U1
Appel, NM; De Souza, EB; Garlick, RK; Glennon, RA; Mitchell, WM; Teitler, M1
Hoffman, AJ; Mathis, CA; McKenna, DJ; Nazarali, AJ; Nichols, DE; Saavedra, JM1
Peroutka, SJ; Pierce, PA2
Buckholtz, NS; Freedman, DX; Zhou, DF1
McKenna, DJ; Saavedra, JM1
Geyer, MA; Krebs, KM1
Artymyshyn, RP; Ferry, RC; Molinoff, PB; Unsworth, CD1
Huang, X; Marona-Lewicka, D; Nichols, DE; Pfaff, RC1
Gallaher, TK; Shih, JC; Wang, CD1
Ferry, RC; Molinoff, PB; Unsworth, CD1
Aghajanian, GK; Marek, GJ1
Carey, JE; Chen, C; Elliott, JM; Flanigan, TP; Kumar, C; McDonald, B; Newberry, NR; Newton, RA; Phipps, SL1
Assié, MB; Kleven, MS; Koek, W1
Geyer, MA; Krebs-Thomson, K; Paulus, MP1
Fowler, CJ; Sjöberg, E; Tiger, G1
Berg, KA; Clarke, WP; Cropper, JD; Emeson, RB; Niswender, CM; Sanders-Bush, E1
Evenden, J1
Marona-Lewicka, D; Nichols, DE; Thisted, RA1
Barrett, RJ; Gresch, PJ; Sanders-Bush, E; Smith, RL1
Brunden, K; Doucette, C; Graham, E; Hanniford, D; Harrington, J; Poole, MF; Sherf, B; Song, J; Stricker-Krongrad, A; Ting, A1
Fernandes, KA; Jha, S; Rajendran, R; Vaidya, VA1
Chemel, BR; Marona-Lewicka, D; Nichols, DE1
Aloyo, VJ; Dave, KD; Harvey, JA; Schindler, EA; Smolock, EM1
Aloyo, VJ; Harvey, JA; Schindler, EA1
Geyer, MA; Halberstadt, AL1
Goda, SA; Hunt, MJ; Kasicki, S; Olszewski, M; Piasecka, J1
Agnati, LF; Borroto-Escuela, DO; Fuxe, K; Narvaez, M; Oflijan, J; Romero-Fernandez, W1
Bowen, JP; Daphney, CM; Guner, OF; Moniri, NH; Murnane, KS; Murphy, TJ; Oppong-Damoah, A; Rambacher, KM; Rice, KC1

Reviews

1 review(s) available for lysergic acid diethylamide and 4-iodo-2,5-dimethoxyphenylisopropylamine

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

42 other study(ies) available for lysergic acid diethylamide and 4-iodo-2,5-dimethoxyphenylisopropylamine

ArticleYear
Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Binding Sites; Binding, Competitive; Ergolines; Ketanserin; Male; Molecular Structure; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship; Tritium

1992
Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA).
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antidepressive Agents; Behavior, Animal; Brain; Dioxoles; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Serotonin Agents; Synaptosomes

1998
A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor.
    Journal of medicinal chemistry, 1998, Dec-17, Volume: 41, Issue:26

    Topics: Animals; Benzofurans; Binding, Competitive; Discrimination Learning; Humans; In Vitro Techniques; Ligands; Prefrontal Cortex; Propylamines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Agents

1998
Thieno[3,2-b]- and thieno[2,3-b]pyrrole bioisosteric analogues of the hallucinogen and serotonin agonist N,N-dimethyltryptamine.
    Journal of medicinal chemistry, 1999, Mar-25, Volume: 42, Issue:6

    Topics: Amphetamines; Animals; Cell Line; Cloning, Molecular; Cricetinae; Discrimination Learning; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; N,N-Dimethyltryptamine; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiophenes; Tryptamines

1999
Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Animals; Binding, Competitive; Discrimination Learning; Frontal Lobe; In Vitro Techniques; Indoles; Lysergic Acid Diethylamide; Male; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship; Tryptamines

1999
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
    Synapse (New York, N.Y.), 2000, Volume: 35, Issue:2

    Topics: Animals; Cell Line; Computer Simulation; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Signal Transduction; Transfection; Tritium

2000
Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.
    Journal of medicinal chemistry, 2000, Nov-30, Volume: 43, Issue:24

    Topics: 3T3 Cells; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Discrimination Learning; Drug Evaluation, Preclinical; Fluorine; Hallucinogens; Humans; Hydrolysis; Mice; Phosphatidylinositols; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines

2000
A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties.
    Bioorganic & medicinal chemistry letters, 2001, Mar-26, Volume: 11, Issue:6

    Topics: Fluorides; Indoles; Pyrrolidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Tryptamines

2001
High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Binding Sites; Cell Line; Cell Line, Tumor; DNA-Binding Proteins; Ethylamines; Humans; Intracellular Signaling Peptides and Proteins; Iodine Radioisotopes; Iodobenzenes; Ketanserin; Nuclear Proteins; Radioligand Assay; Radiopharmaceuticals; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Tritium; Tumor Necrosis Factor alpha-Induced Protein 3

2008
Dissociation of multiple effects of acute LSD on exploratory behavior in rats by ritanserin and propranolol.
    Psychopharmacology, 1991, Volume: 105, Issue:1

    Topics: Amphetamines; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Lysergic Acid Diethylamide; Male; Propranolol; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists

1991
Autoradiographic studies of 5HT2 receptors.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Amphetamines; Animals; Autoradiography; Blood Platelets; Brain Chemistry; Hallucinogens; Humans; Ketanserin; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists

1991
Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:6

    Topics: Amphetamines; Anesthesia; Animals; Behavior, Animal; Brain Chemistry; Carbon Dioxide; Creatine Kinase; Female; Lactates; Lysergic Acid Diethylamide; Male; Malignant Hyperthermia; Methoxydimethyltryptamines; Oxygen; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Swine

1990
Autoradiographic characterization of (+-)-1-(2,5-dimethoxy-4-[125I] iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Amphetamines; Animals; Autoradiography; Brain; Brain Chemistry; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Iodine Radioisotopes; Ketanserin; Lysergic Acid Diethylamide; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists

1990
Human platelet [125I]R-DOI binding sites. Characterization by in vitro autoradiography.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:1

    Topics: Adult; Amphetamines; Autoradiography; Binding, Competitive; Blood Platelets; Cell Membrane; Female; Humans; Iodine Radioisotopes; Ketanserin; Kinetics; Lysergic Acid Diethylamide; Male; Receptors, Serotonin; Stereoisomerism

1990
Common receptors for hallucinogens in rat brain: a comparative autoradiographic study using [125I]LSD and [125I]DOI, a new psychotomimetic radioligand.
    Brain research, 1989, Jan-02, Volume: 476, Issue:1

    Topics: Amphetamines; Animals; Autoradiography; Brain; Hallucinogens; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Stereoisomerism

1989
Hallucinogenic drug interactions with neurotransmitter receptor binding sites in human cortex.
    Psychopharmacology, 1989, Volume: 97, Issue:1

    Topics: Amphetamines; Bromine Radioisotopes; Cerebral Cortex; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Humans; In Vitro Techniques; Lysergic Acid Diethylamide; N,N-Dimethyltryptamine; Receptors, Neurotransmitter; Receptors, Serotonin

1989
Antagonism of 5-hydroxytryptamine2 receptor-mediated phosphatidylinositol turnover by d-lysergic acid diethylamide.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3

    Topics: Amphetamines; Animals; Cerebral Cortex; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Guanosine Triphosphate; In Vitro Techniques; Ketanserin; Lysergic Acid Diethylamide; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Serotonin

1988
Serotonin2 agonist administration down-regulates rat brain serotonin2 receptors.
    Life sciences, 1988, Volume: 42, Issue:24

    Topics: Amphetamines; Animals; Brain; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Ketanserin; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1988
Autoradiography of LSD and 2,5-dimethoxyphenylisopropylamine psychotomimetics demonstrates regional, specific cross-displacement in the rat brain.
    European journal of pharmacology, 1987, Oct-13, Volume: 142, Issue:2

    Topics: Amphetamines; Animals; Autoradiography; Binding, Competitive; Brain; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Lysergic Acid Diethylamide; Rats

1987
Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats.
    Psychopharmacology, 1994, Volume: 113, Issue:3-4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Lysergic Acid Diethylamide; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists

1994
Regulation of mRNA encoding 5-HT2A receptors in P11 cells through a post-transcriptional mechanism requiring activation of protein kinase C.
    The Journal of biological chemistry, 1994, Dec-16, Volume: 269, Issue:50

    Topics: Amino Acid Isomerases; Amphetamines; Animals; Base Sequence; Carrier Proteins; Cell Line; Cycloheximide; DNA Primers; Down-Regulation; Enzyme Activation; Gene Expression Regulation; In Vitro Techniques; Lysergic Acid Diethylamide; Molecular Sequence Data; Norepinephrine; Peptidylprolyl Isomerase; Pituitary Gland; Protein Kinase C; Rats; Receptors, Serotonin; RNA Processing, Post-Transcriptional; RNA, Messenger; Serotonin; Transcription, Genetic

1994
Drug discrimination and receptor binding studies of N-isopropyl lysergamide derivatives.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Binding, Competitive; Conditioning, Operant; Discrimination, Psychological; Hallucinogens; Iodine Radioisotopes; Ketanserin; Lysergic Acid Diethylamide; Male; Models, Molecular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement Schedule

1994
Site-directed mutagenesis of the serotonin 5-hydroxytrypamine2 receptor: identification of amino acids necessary for ligand binding and receptor activation.
    Molecular pharmacology, 1993, Volume: 43, Issue:6

    Topics: 3T3 Cells; Amphetamines; Animals; Asparagine; Aspartic Acid; Binding, Competitive; Guanosine Triphosphate; Hydrolysis; Lysergic Acid Diethylamide; Mice; Mutagenesis, Site-Directed; Phosphatidylinositols; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Effects of agonists, partial agonists, and antagonists on the regulation of 5-hydroxytryptamine2 receptors in P11 cells.
    Molecular pharmacology, 1993, Volume: 43, Issue:5

    Topics: Amphetamines; Animals; Down-Regulation; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mianserin; Phosphatidylinositols; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tumor Cells, Cultured

1993
LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; In Vitro Techniques; Interneurons; Lysergic Acid Diethylamide; Male; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
    Journal of neurochemistry, 1996, Volume: 67, Issue:6

    Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysiology; Ergolines; Ergotamine; Frontal Lobe; Hallucinogens; Humans; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mescaline; Methoxydimethyltryptamines; Neuroblastoma; Phosphatidylinositols; Piperazines; Quipazine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured

1996
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzopyrans; Discrimination, Psychological; Ketanserin; Lysergic Acid Diethylamide; Male; Nicotinic Acids; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists

1997
Effects of hallucinogens on locomotor and investigatory activity and patterns: influence of 5-HT2A and 5-HT2C receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:5

    Topics: Amphetamines; Animals; Exploratory Behavior; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1998
Serotonin stimulation of calcium mobilisation in human platelets: choice of units of measurement, effects of age and tobacco use, and correlation with serotonin2A receptor density.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 287, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amphetamines; Blood Platelets; Calcium; Female; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Nicotiana; Plants, Toxic; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Smoking; Spectrometry, Fluorescence; Thrombin; Tritium

1999
RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Amphetamines; Animals; Arachidonic Acid; Binding, Competitive; Bufotenin; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ergolines; Inositol Phosphates; Lysergic Acid Diethylamide; Piperazines; Protein Isoforms; Quipazine; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA Editing; Serotonin; Serotonin Receptor Agonists; Tritium

2001
The effects of psychotomimetics and psychomotor stimulants on two schedules promoting response switching in the rat.
    Psychopharmacology, 2002, Volume: 163, Issue:3-4

    Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Atropine; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Food; Hallucinogens; Lysergic Acid Diethylamide; Muscarinic Antagonists; Phencyclidine; Photic Stimulation; Rats; Rats, Long-Evans; Reinforcement Schedule; Scopolamine

2002
Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis.
    Psychopharmacology, 2005, Volume: 180, Issue:3

    Topics: Amphetamine; Amphetamines; Animals; Apomorphine; Behavior, Animal; Cues; Discrimination Learning; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Haloperidol; Indans; Injections, Intraperitoneal; Lysergic Acid Diethylamide; Male; Piperidines; Psychotic Disorders; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2005
Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:9

    Topics: Amphetamines; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Cerebral Cortex; Diagnostic Imaging; Drug Interactions; Drug Tolerance; Fluorobenzenes; Guanosine 5'-O-(3-Thiotriphosphate); Hallucinogens; Indoles; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Piperidines; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Signal Transduction; Sulfur Isotopes; Time Factors

2005
Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes.
    Assay and drug development technologies, 2005, Volume: 3, Issue:6

    Topics: Amphetamines; Binding, Competitive; Calcium Signaling; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ergolines; Humans; Ketanserin; Lysergic Acid Diethylamide; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

2005
5-HT2A/2C receptor blockade regulates progenitor cell proliferation in the adult rat hippocampus.
    Neuroscience letters, 2008, Aug-22, Volume: 441, Issue:2

    Topics: Adult Stem Cells; Amphetamines; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Doublecortin Domain Proteins; Drug Administration Schedule; Hippocampus; Ketanserin; Lysergic Acid Diethylamide; Male; Microtubule-Associated Proteins; Neuropeptides; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI.
    Psychopharmacology, 2009, Volume: 203, Issue:2

    Topics: Amphetamines; Animals; Benzimidazoles; Binding, Competitive; Cell Line; Cyclic AMP; Discrimination, Psychological; Dose-Response Relationship, Drug; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Piperazines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4

2009
Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:1

    Topics: Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dopamine; Frontal Lobe; Hallucinogens; Ketanserin; Lysergic Acid Diethylamide; Male; Rabbits; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Ritanserin; Serotonin; Serotonin Agents; Serotonin Antagonists; Temperature

2012
Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex.
    Brain research, 2013, Jan-23, Volume: 1491

    Topics: Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Estrenes; Hallucinogens; Head Movements; Hydrolysis; Lysergic Acid Diethylamide; Male; Microinjections; Phosphatidylinositols; Prefrontal Cortex; Pyrrolidinones; Rabbits; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Type C Phospholipases

2013
Characterization of the head-twitch response induced by hallucinogens in mice: detection of the behavior based on the dynamics of head movement.
    Psychopharmacology, 2013, Volume: 227, Issue:4

    Topics: Amphetamine; Amphetamines; Animals; Behavior, Animal; Hallucinogens; Head Movements; High-Throughput Screening Assays; Lisuride; Lysergic Acid Diethylamide; Magnetometry; Male; Mice; Mice, Inbred C57BL; Sensitivity and Specificity; Video Recording

2013
Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens.
    Psychopharmacology, 2013, Volume: 228, Issue:2

    Topics: Amphetamines; Animals; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Hallucinogens; Injections, Intraperitoneal; Ketamine; Lysergic Acid Diethylamide; Male; Methylamines; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists

2013
Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes.
    Biochemical and biophysical research communications, 2014, Jan-03, Volume: 443, Issue:1

    Topics: Amphetamines; Animals; Basal Ganglia; Gene Expression Regulation; Genes, Reporter; Hallucinogens; HEK293 Cells; Humans; Ketanserin; Luciferases; Lysergic Acid Diethylamide; Male; Promoter Regions, Genetic; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2014
The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 181

    Topics: Adrenergic Antagonists; Amphetamines; Animals; Behavior, Animal; Binding Sites; Carvedilol; Computational Chemistry; Drug Discovery; Fluorobenzenes; HEK293 Cells; Humans; Lysergic Acid Diethylamide; Male; Mice; Models, Animal; Models, Molecular; Piperidines; Protein Binding; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Transfection

2019