lycopladine-a and 1-3-cyclohexanedione

lycopladine-a has been researched along with 1-3-cyclohexanedione* in 1 studies

Other Studies

1 other study(ies) available for lycopladine-a and 1-3-cyclohexanedione

Article	Year
Total synthesis of optically active lycopladine A by utilizing diastereoselective protection of carbonyl group in a 1,3-cyclohexanedione derivative. The Journal of organic chemistry, 2011, Jun-03, Volume: 76, Issue:11 We successfully synthesized two enantiomers of bicyclic enones, (7R,7aR)- and (7S,7aS)-9, from the hemiacetal 2a, which we first synthesized from the symmetrical diketone 1a via diastereoselective carbon-oxygen bond formation between one of the carbonyl groups and the chiral alcohol on the C2 side chain in a 2,2-disubstituted 1,3-cycloalkanedione derivative. We also report the total synthesis of natural (+)-lycopladine A [(+)-6] from (7R,7aR)-9 and the formal synthesis of unnatural (-)-lycopladine A [(-)-6] from (7S,7aS)-9. Topics: Cyclohexanones; Ketones; Optical Phenomena; Sesquiterpenes; Stereoisomerism; Substrate Specificity	2011

Article

Year

Total synthesis of optically active lycopladine A by utilizing diastereoselective protection of carbonyl group in a 1,3-cyclohexanedione derivative.

The Journal of organic chemistry, 2011, Jun-03, Volume: 76, Issue:11

We successfully synthesized two enantiomers of bicyclic enones, (7R,7aR)- and (7S,7aS)-9, from the hemiacetal 2a, which we first synthesized from the symmetrical diketone 1a via diastereoselective carbon-oxygen bond formation between one of the carbonyl groups and the chiral alcohol on the C2 side chain in a 2,2-disubstituted 1,3-cycloalkanedione derivative. We also report the total synthesis of natural (+)-lycopladine A [(+)-6] from (7R,7aR)-9 and the formal synthesis of unnatural (-)-lycopladine A [(-)-6] from (7S,7aS)-9.

Topics: Cyclohexanones; Ketones; Optical Phenomena; Sesquiterpenes; Stereoisomerism; Substrate Specificity

2011