ly 300164 has been researched along with kainic acid in 5 studies
| Studies (ly 300164) | Trials (ly 300164) | Recent Studies (post-2010) (ly 300164) | Studies (kainic acid) | Trials (kainic acid) | Recent Studies (post-2010) (kainic acid) |
|---|---|---|---|---|---|
| 73 | 7 | 12 | 9,540 | 3 | 1,775 |
| Protein | Taxonomy | ly 300164 (IC50) | kainic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 4 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.0126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cagnotto, A; Colleoni, S; Diana, V; Grasso, S; Lazzaro, J; Mennini, T; Micale, N; Pellicanò, A; Postorino, G; Zappalà , M | 1 |
| Klaassen, H; Robberecht, W; Van Den Bosch, L; Van Houtte, E; Vandenberghe, W | 1 |
| Jiang, L; Kang, J; Nedergaard, M; Xu, J | 1 |
| Aujla, PK; Fetell, MR; Jensen, FE | 1 |
| Chavda, V; Dhir, A | 1 |
5 other study(ies) available for ly 300164 and kainic acid
| Article | Year |
|---|---|
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Calcium; Cells, Cultured; Hippocampus; Inhibitory Concentration 50; Kainic Acid; Ligands; Mice; Molecular Structure; Neurons; Neuroprotective Agents; Protein Binding; Receptors, AMPA; Structure-Activity Relationship | 2008 |
Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amyotrophic Lateral Sclerosis; Animals; Benzodiazepines; Calcium Channels; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kainic Acid; Motor Neurons; Neurotoxins; Nifedipine; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, AMPA; Spider Venoms | 2000 |
A kainate receptor increases the efficacy of GABAergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Benzodiazepines; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neurons; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Staurosporine; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2001 |
Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Brain; Cell Death; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Hypoxia; Kainic Acid; Rats; Rats, Long-Evans; Receptors, AMPA; Seizures; Time Factors | 2009 |
Pre- and post-exposure talampanel (GYKI 53773) against kainic acid seizures in neonatal rats.
Topics: Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, AMPA; Seizures | 2016 |