ly 300164 has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 5 studies
| Studies (ly 300164) | Trials (ly 300164) | Recent Studies (post-2010) (ly 300164) | Studies (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Trials (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) |
|---|---|---|---|---|---|
| 73 | 7 | 12 | 2,899 | 11 | 609 |
| Protein | Taxonomy | ly 300164 (IC50) | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.157 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 1 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 2 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 3 | Mus musculus (house mouse) | 0.04 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henley, JM; Szabó, G | 1 |
| Ballyk, BA; Bath, CP; Bleakman, D; Bufton, HR; Kamboj, RK; Lodge, D; Palmer, AJ; Schoepp, DD; Sharpe, EF; Tarnawa, I; Woolley, ML | 1 |
| Anderson, BA; Hansen, MM; Harkness, AR; Harn, NK; Leander, JD; Lodge, D | 1 |
| Banczerowski-Pelyhe, I; Gulyás-Kovács, A; Takács, J; Tarnawa, I; Világi, I | 1 |
| Agoston, M; Albert, M; Barkóczy, J; Benedek, A; Gacsályi, I; Gigler, G; Hársing, LG; Kapus, G; Kertész, S; Lévay, G; Markó, B; Matucz, E; Móricz, K; Simó, A; Szabó, G; Szénási, G; Vegh, M | 1 |
5 other study(ies) available for ly 300164 and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
| Article | Year |
|---|---|
Binding of the AMPA receptor antagonist [3H]GYKI 53405 to Xenopus brain membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Brain; Cell Membrane; Central Nervous System; Kinetics; Radioligand Assay; Receptors, AMPA; Tritium; Xenopus | 1993 |
Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Humans; Kidney; Membrane Potentials; Molecular Structure; Neurons; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; Spinal Cord; Structure-Activity Relationship; Transfection | 1996 |
Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazephine AMPA antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Dose-Response Relationship, Drug; Electroshock; Mice; Seizures; Structure-Activity Relationship | 1999 |
Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anti-Anxiety Agents; Asphyxia Neonatorum; Behavior, Animal; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Movement Disorders; Neostriatum; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Synaptic Transmission | 2002 |
Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Brain; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gerbillinae; Male; Membrane Potentials; Mice; Mice, Inbred DBA; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Purkinje Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Seizures; Telencephalon; Time Factors | 2007 |