Page last updated: 2024-09-03

ly 293558 and u-50488

ly 293558 has been researched along with u-50488 in 1 studies

Compound Research Comparison

Studies
(ly 293558)
Trials
(ly 293558)
Recent Studies (post-2010)
(ly 293558)
Studies
(u-50488)
Trials
(u-50488)
Recent Studies (post-2010) (u-50488)
1034181,6643209

Protein Interaction Comparison

ProteinTaxonomyly 293558 (IC50)u-50488 (IC50)
Delta-type opioid receptorRattus norvegicus (Norway rat)2.15
Kappa-type opioid receptorMus musculus (house mouse)0.0027
Mu-type opioid receptorRattus norvegicus (Norway rat)2.15
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.7171
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.0958
Kappa-type opioid receptorHomo sapiens (human)0.0537

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inturrisi, CE; Kao, B; Kest, B; McLemore, G1

Other Studies

1 other study(ies) available for ly 293558 and u-50488

ArticleYear
The competitive alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist LY293558 attenuates and reverses analgesic tolerance to morphine but not to delta or kappa opioids.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Isoquinolines; Male; Mice; Morphine; Receptors, AMPA; Receptors, Opioid, delta; Receptors, Opioid, kappa; Tetrazoles

1997