Compounds > ly 293558
Page last updated: 2024-09-03

ly 293558 and naloxone

ly 293558 has been researched along with naloxone in 1 studies

Compound Research Comparison

Studies
(ly 293558)		Trials
(ly 293558)		Recent Studies (post-2010)
(ly 293558)		Studies
(naloxone)		Trials
(naloxone)		Recent Studies (post-2010) (naloxone)
10341820,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomyly 293558 (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inturrisi, CE; Kest, B; McLemore, GL1

Other Studies

1 other study(ies) available for ly 293558 and naloxone

ArticleYear
The effects of LY293558, an AMPA receptor antagonist, on acute and chronic morphine dependence.
    Brain research, 1997, Dec-05, Volume: 778, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Tolerance; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Isoquinolines; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Narcotic Antagonists; Receptors, AMPA; Tetrazoles

1997