ly 293558 has been researched along with baclofen in 2 studies
| Studies (ly 293558) | Trials (ly 293558) | Recent Studies (post-2010) (ly 293558) | Studies (baclofen) | Trials (baclofen) | Recent Studies (post-2010) (baclofen) |
|---|---|---|---|---|---|
| 103 | 4 | 18 | 6,017 | 372 | 1,535 |
| Protein | Taxonomy | ly 293558 (IC50) | baclofen (IC50) |
|---|---|---|---|
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | 0.2762 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | 0.2762 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goiriena, E; Gómez-Soriano, J; Taylor, J | 1 |
| Hefferan, MP; Kakinohana, O; Lukacova, N; Marsala, M; Oshiro, M; Sugahara, K; Yaksh, TL | 1 |
2 other study(ies) available for ly 293558 and baclofen
| Article | Year |
|---|---|
Spasticity therapy reacts to astrocyte GluA1 receptor upregulation following spinal cord injury.
Topics: Animals; Astrocytes; Baclofen; Humans; Injections, Spinal; Isoquinolines; Muscle Relaxants, Central; Muscle Spasticity; Receptors, AMPA; Spinal Cord Injuries; Substance Withdrawal Syndrome; Tetrazoles; Up-Regulation | 2010 |
Suppression of stretch reflex activity after spinal or systemic treatment with AMPA receptor antagonist NGX424 in rats with developed baclofen tolerance.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Drug Tolerance; GABA-B Receptor Agonists; Injections, Spinal; Injections, Subcutaneous; Isoquinolines; Male; Muscle Relaxants, Central; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex, Stretch; Tetrazoles | 2010 |