ly 293284 has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 3 studies
*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]
*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]
| Studies (ly 293284) | Trials (ly 293284) | Recent Studies (post-2010) (ly 293284) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 10 | 0 | 0 | 3,530 | 7 | 389 |
| Protein | Taxonomy | ly 293284 (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barker, EL; Blair, JB; Cumbay, MG; Kurrasch-Orbaugh, D; Marona-Lewicka, D; Nichols, DE; Watts, VJ | 1 |
| Lisinicchia, JG; Watts, VJ | 1 |
| Marona-Lewicka, D; Nichols, DE | 1 |
3 other study(ies) available for ly 293284 and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.
Topics: 3T3 Cells; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Discrimination Learning; Drug Evaluation, Preclinical; Fluorine; Hallucinogens; Humans; Hydrolysis; Mice; Phosphatidylinositols; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines | 2000 |
Sensitization of adenylate cyclase by short-term activation of 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Arachidonic Acid; Buspirone; Calcimycin; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Humans; Indoles; Indomethacin; Maleimides; Pertussis Toxin; Phorbol Esters; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Time Factors; Tryptamines | 2003 |
WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D(4) receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Benzimidazoles; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Therapy, Combination; Pindolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Reinforcement Schedule; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Sulfonamides; Tryptamines | 2009 |