Page last updated: 2024-09-05

ly 293111 and sc 41930

ly 293111 has been researched along with sc 41930 in 4 studies

Compound Research Comparison

Studies
(ly 293111)
Trials
(ly 293111)
Recent Studies (post-2010)
(ly 293111)
Studies
(sc 41930)
Trials
(sc 41930)
Recent Studies (post-2010) (sc 41930)
38965400

Protein Interaction Comparison

ProteinTaxonomyly 293111 (IC50)sc 41930 (IC50)
Leukotriene B4 receptor 1Homo sapiens (human)0.6716
Leukotriene B4 receptor 2Homo sapiens (human)2.045

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bach, NJ; Baker, SR; Baldwin, RF; Borromeo, PS; Cockerham, SL; Fleisch, JH; Floreancig, P; Froelich, LL; Jackson, WT; Sawyer, JS1
Brooks, CD; Summers, JB1
Froelich, LL; Mann, LL; Marder, P; Sawyer, JS; Spaethe, SM1
Bendele, AM; Cockerham, SL; Froelich, LL; Jackson, WT; Sawyer, JS; Silbaugh, SA; Sofia, MJ; Spaethe, SM; Stengel, PW1

Reviews

1 review(s) available for ly 293111 and sc 41930

ArticleYear
Modulators of leukotriene biosynthesis and receptor activation.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene

1996

Other Studies

3 other study(ies) available for ly 293111 and sc 41930

ArticleYear
Synthetic and structure/activity studies on acid-substituted 2-arylphenols: discovery of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]-propoxy]phenoxy]benzoic acid, a high-affinity leukotriene B4 receptor antagonist.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Airway Obstruction; Animals; Benzoates; Guinea Pigs; Humans; Leukotriene B4; Lung; Neutrophils; Phenols; Receptors, Leukotriene B4; Structure-Activity Relationship; Tetrazoles

1995
Blockade of human neutrophil activation by 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]propoxy]phenoxy]benzoic acid (LY293111), a novel leukotriene B4 receptor antagonist.
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: Benzoates; Benzopyrans; Binding, Competitive; Calcium; CD11 Antigens; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Neutrophil Activation; Neutrophils; Receptors, Leukotriene B4; Up-Regulation

1995
Pharmacologic actions of the second generation leukotriene B4 receptor antagonist LY29311: in vivo pulmonary studies.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:4

    Topics: Airway Obstruction; Animals; Benzoates; Benzopyrans; Bronchoalveolar Lavage Fluid; Calcimycin; Chemotaxis, Leukocyte; Dinoprostone; Granulocytes; Guinea Pigs; Inflammation; Leukotriene Antagonists; Leukotriene B4; Lung; Male; Receptors, Leukotriene B4; Thromboxane B2

2000