Page last updated: 2024-09-03

ly 274614 and sirolimus

ly 274614 has been researched along with sirolimus in 1 studies

Compound Research Comparison

Studies
(ly 274614)
Trials
(ly 274614)
Recent Studies (post-2010)
(ly 274614)
Studies
(sirolimus)
Trials
(sirolimus)
Recent Studies (post-2010) (sirolimus)
9601520,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomyly 274614 (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joca, SRL; Pereira, VS; Suavinha, ACDR; Wegener, G1

Other Studies

1 other study(ies) available for ly 274614 and sirolimus

ArticleYear
Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades.
    Acta neuropsychiatrica, 2019, Volume: 31, Issue:3

    Topics: Animals; Antidepressive Agents; Apomorphine; Brain-Derived Neurotrophic Factor; Carbazoles; Immobility Response, Tonic; Indazoles; Indole Alkaloids; Isoquinolines; Ketamine; Locomotion; Male; Microinjections; Nitric Oxide Synthase Type I; Ornithine; Prefrontal Cortex; Rats; Receptor, trkB; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2019