Page last updated: 2024-09-03

ly 274614 and methadone

ly 274614 has been researched along with methadone in 2 studies

Compound Research Comparison

Studies (ly 274614)	Trials (ly 274614)	Recent Studies (post-2010) (ly 274614)	Studies (methadone)	Trials (methadone)	Recent Studies (post-2010) (methadone)
96	0	15	13,630	1,463	3,957

Protein Interaction Comparison

Protein	Taxonomy	methadone (IC50)
ATP-dependent translocase ABCB1	Homo sapiens (human)	7.5
Mu-type opioid receptor	Homo sapiens (human)	0.0041
Delta-type opioid receptor	Homo sapiens (human)	1.09
Kappa-type opioid receptor	Homo sapiens (human)	0.512
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	9.7724

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrigan, KA; Dykstra, LA; Fischer, BD	1
Mendez, IA; Trujillo, KA	1

Other Studies

2 other study(ies) available for ly 274614 and methadone

Article	Year
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice. The journal of pain, 2005, Volume: 6, Issue:7 Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidinones; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	2005
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats. Psychopharmacology, 2008, Volume: 196, Issue:3 Topics: Animals; Behavior, Animal; Buprenorphine; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Memantine; Methadone; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2008

Article

Year

Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.

The journal of pain, 2005, Volume: 6, Issue:7

Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidinones; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2005

NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats.

Psychopharmacology, 2008, Volume: 196, Issue:3

Topics: Animals; Behavior, Animal; Buprenorphine; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Memantine; Methadone; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2008