Compounds > ly 274614
Page last updated: 2024-09-03

ly 274614 and memantine

ly 274614 has been researched along with memantine in 2 studies

Compound Research Comparison

Studies
(ly 274614)		Trials
(ly 274614)		Recent Studies (post-2010)
(ly 274614)		Studies
(memantine)		Trials
(memantine)		Recent Studies (post-2010) (memantine)
960152,6843411,425

Protein Interaction Comparison

ProteinTaxonomyly 274614 (IC50)memantine (IC50)
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)6
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)6
AcetylcholinesteraseHomo sapiens (human)0.0049
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4167
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)6
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)1.4167
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)1.5
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)1.5
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)4.3212
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)3.662
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)5.31
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)1.5
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)1.5
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)1.5

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendez, IA; Trujillo, KA1
Kloc, R; Luchowska, E; Owe-Larsson, B; Urbanska, EM; Wielosz, M1

Other Studies

2 other study(ies) available for ly 274614 and memantine

ArticleYear
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats.
    Psychopharmacology, 2008, Volume: 196, Issue:3

    Topics: Animals; Behavior, Animal; Buprenorphine; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Memantine; Methadone; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2008
Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism.
    Neuroscience letters, 2008, Apr-18, Volume: 435, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Carbazoles; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Male; Memantine; Neurons; Piperidines; Pyrroles; Rats; Rats, Wistar

2008