ly 274614 has been researched along with enkephalin, leucine in 5 studies
| Studies (ly 274614) | Trials (ly 274614) | Recent Studies (post-2010) (ly 274614) | Studies (enkephalin, leucine) | Trials (enkephalin, leucine) | Recent Studies (post-2010) (enkephalin, leucine) |
|---|---|---|---|---|---|
| 96 | 0 | 15 | 11,524 | 80 | 754 |
| Protein | Taxonomy | ly 274614 (IC50) | enkephalin, leucine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0142 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0417 | |
| Mu-type opioid receptor | Homo sapiens (human) | 9.5 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0308 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.246 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inturrisi, CE; Zhu, YS | 1 |
| Bhargava, HN; Zhao, GM | 1 |
| Bharagava, HN; Zhao, GM | 1 |
| Bilsky, EJ; Hruby, VJ; Inturrisi, CE; Porreca, F; Sadée, W | 1 |
| Bhargava, HN; Bian, JT; Cao, YJ | 1 |
5 other study(ies) available for ly 274614 and enkephalin, leucine
| Article | Year |
|---|---|
Metrazole induction of c-fos and proenkephalin gene expression in the rat adrenal and hippocampus: pharmacological characterization.
Topics: Adrenal Glands; Animals; Calcium; Calmodulin; Cholinergic Antagonists; Enkephalins; Gene Expression Regulation; Genes, fos; Hippocampus; Isoquinolines; Male; Pentylenetetrazole; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Trifluoperazine | 1993 |
Effect of antagonism of the NMDA receptor on tolerance to [D-Pen2,D-Pen5]enkephalin, a delta 1-opioid receptor agonist.
Topics: Analgesics; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Isoquinolines; Male; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1996 |
Effects of competitive and noncompetitive antagonists of the N-methyl-D-aspartate receptor on the analgesic action of delta 1- and delta 2-opioid receptor agonists in mice.
Topics: Analgesics, Opioid; Animals; Antiparkinson Agents; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Isoquinolines; Male; Membranes; Mice; Oligopeptides; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1996 |
Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Dizocilpine Maleate; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Fentanyl; Isoquinolines; Male; Mice; Mice, Inbred ICR; Morphine; Oligopeptides; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Effects of NMDA receptor antagonists on delta1- and delta2-opioid receptor agonists-induced changes in the mouse brain [3H]DPDPE binding.
Topics: Animals; Brain; Dizocilpine Maleate; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Membranes; Mice; Oligopeptides; Protein Binding; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1997 |