ly 274614 has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 2 studies
| Studies (ly 274614) | Trials (ly 274614) | Recent Studies (post-2010) (ly 274614) | Studies (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Trials (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) |
|---|---|---|---|---|---|
| 96 | 0 | 15 | 2,899 | 11 | 609 |
| Protein | Taxonomy | ly 274614 (IC50) | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.157 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 1 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 2 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 3 | Mus musculus (house mouse) | 0.04 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leander, JD; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| Greenamyre, JT; Greene, JG | 1 |
2 other study(ies) available for ly 274614 and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
| Article | Year |
|---|---|
Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; Cell Death; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Isoquinolines; Male; Malonates; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |