Page last updated: 2024-09-03

ly 206130 and fluoxetine

ly 206130 has been researched along with fluoxetine in 3 studies

Compound Research Comparison

Studies
(ly 206130)
Trials
(ly 206130)
Recent Studies (post-2010)
(ly 206130)
Studies
(fluoxetine)
Trials
(fluoxetine)
Recent Studies (post-2010) (fluoxetine)
70010,1001,6633,263

Protein Interaction Comparison

ProteinTaxonomyly 206130 (IC50)fluoxetine (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)5.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.119
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.303
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.358
Cytochrome P450 2D6Homo sapiens (human)0.7
Muscarinic acetylcholine receptor M1Homo sapiens (human)3.203
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)5.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.528
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)5.2
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.595
AcetylcholinesteraseHomo sapiens (human)0.13
Prostaglandin G/H synthase 1Homo sapiens (human)6
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.8332
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)6
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.452
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.1395
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)5.2
Sodium-dependent serotonin transporterHomo sapiens (human)0.0342
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.0538
Cytochrome P450 2C19Homo sapiens (human)0.0525
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)5.2
5-hydroxytryptamine receptor 6Homo sapiens (human)1.661
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)5.2
Sodium-dependent dopamine transporter Homo sapiens (human)5.984
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.3513
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)5.2
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0094
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)5.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.6751
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)5.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Engleman, E; Fuller, RW; Hemrick-Luecke, SK; Perry, KW1
Browning, RA; Dailey, JW; Jobe, PC; Merrill, MA; Wood, AV1
Iyengar, S; Li, DL; Simmons, RM1

Other Studies

3 other study(ies) available for ly 206130 and fluoxetine

ArticleYear
Serum corticosterone increases reflect enhanced uptake inhibitor-induced elevation of extracellular 5-hydroxytryptamine in rat hypothalamus.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Corticosterone; Cyclohexylamines; Drug Synergism; Fluoxetine; Hypothalamus; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

1996
Enhancement of the anticonvulsant effect of fluoxetine following blockade of 5-HT1A receptors.
    European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Cyclohexylamines; Drug Interactions; Female; Fenclonine; Fluoxetine; Norepinephrine; Pindolol; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Seizures; Serotonin; Serotonin Antagonists

1997
5HT1A receptor antagonists enhance the functional activity of fluoxetine in a mouse model of feeding.
    Brain research, 1998, Jan-19, Volume: 781, Issue:1-2

    Topics: Animals; Cyclohexylamines; Drinking Behavior; Drug Synergism; Feeding Behavior; Fluoxetine; Male; Mice; Mice, Inbred Strains; Pindolol; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

1998