ly 171883 has been researched along with fpl 55712 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kreft, AF; Musser, JH | 1 |
| Krell, RD; Shaw, A | 1 |
| Campbell, HF; Galemmo, RA; Huang, FC; Johnson, WH; Learn, KS; Lee, TD; O'Rourke, SV; Schuessler, G; Sweeney, DM; Youssefyeh, R | 1 |
| Banner, BL; Chiu, AM; Cohen, N; Focella, A; Lopresti, RJ; O'Donnell, M; Schaer, B; Todaro, L; Weber, G; Zenchoff, GB | 1 |
| Bernstein, PR; Brown, FJ; Cronk, LA; Dosset, DL; Hebbel, KC; Maduskuie, TP; Shapiro, HS; Vacek, EP; Willard, AK; Yee, YK | 1 |
| Carr, FP; Dillard, RD; Fleisch, JH; Haisch, KD; McCullough, D; Rinkema, LE | 1 |
| Brooks, CD; Summers, JB | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Oborin, AN | 1 |
| Adkinson, NF; Ghio, AJ; Guo, YL; Gurtner, GH; Kennedy, TP; Michael, JR; Sciuto, AM | 1 |
| Auen, MA; Englebach, IM; Hand, JM; Kreft, AF; Musser, JH; Schwalm, SF | 1 |
| Lawson, DL; Mehta, JL; Mehta, P; Nichols, WW | 1 |
| Jolly, SR; Travis, J; Van Inwegen, RG | 1 |
| Barnes, N; Costello, J; Evans, J; Piper, P; Zakrzewski, J | 1 |
| Buckner, CK; Castleman, WL; Saban, R; Will, JA | 1 |
| Cloud, ML; Fleisch, JH; Marshall, WS | 1 |
| Heller, J; Horácek, V; Kamarádová, S | 1 |
| Drazen, JM; Shore, SA; Smith, E; Stimler-Gerard, NP | 1 |
| Eimerl, J; Feuerstein, G; Sirén, AL | 1 |
| Cardinali, DP; Etchegoyen, GS; Gimeno, MF; Keller-Sarmiento, MI; Pereyra, EN; Vacas, MI | 1 |
| Ganbo, T; Goto, R; Hisamatsu, K; Murakami, Y; Nakajima, M; Nakazawa, T | 1 |
| Cullinan, GJ; Fleisch, JH; Goodson, T; Haisch, KD; Marshall, WS; Rinkema, LE; Swanson-Bean, D | 1 |
6 review(s) available for ly 171883 and fpl 55712
| Article | Year |
|---|---|
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines | 1992 |
Peptide leukotrienes: current status of research.
Topics: Acetophenones; Humans; Leukotriene Antagonists; Leukotrienes; Molecular Structure; Peptides; Receptors, Immunologic; Receptors, Leukotriene; Tetrazoles | 1991 |
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
[Leukotrienes and shock].
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Arachidonic Acids; Autacoids; Chromones; Fatty Acids, Unsaturated; Humans; Leukotriene Antagonists; Leukotrienes; Shock; SRS-A; Tetrazoles | 1991 |
Studies of leukotriene antagonists and synthesis inhibitors in man.
Topics: Acetophenones; Asthma; Chromones; Epoprostenol; Humans; Hydroxyquinolines; Keto Acids; Leukotriene B4; Phenylbutyrates; Quinolines; SRS-A; Sulfones; Tetrazoles | 1988 |
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles | 1988 |
16 other study(ies) available for ly 171883 and fpl 55712
| Article | Year |
|---|---|
The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency.
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Guinea Pigs; In Vitro Techniques; Lung; Quinolines; Radioligand Assay; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Structure-Activity Relationship | 1990 |
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.
Topics: Animals; Benzopyrans; Chemical Phenomena; Chemistry; Chromans; Guinea Pigs; Leukotriene Antagonists; Male; Models, Molecular; Rats; Receptors, Immunologic; Receptors, Leukotriene; Stereoisomerism; Structure-Activity Relationship | 1989 |
Hydroxyacetophenone-derived antagonists of the peptidoleukotrienes.
Topics: Acetophenones; Animals; Benzoates; Biological Assay; Chemical Phenomena; Chemistry; Chromones; Guinea Pigs; Hydroxylation; Ketones; Methylation; Muscle Contraction; Nitrogen; Phenols; SRS-A; Structure-Activity Relationship; Trachea | 1989 |
Leukotriene receptor antagonists. 2. The [[(tetrazol-5-ylaryl)oxy]methyl]acetophenone derivatives.
Topics: Acetophenones; Animals; Azoles; Bronchi; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea | 1987 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Mechanism of phosgene-induced lung toxicity: role of arachidonate mediators.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Indomethacin; Lung; Male; Methylprednisolone; Phosgene; Potassium Chloride; Pulmonary Circulation; Rabbits; SRS-A; Tetrazoles | 1990 |
Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea.
Topics: Acetophenones; Airway Resistance; Animals; Chromones; Guinea Pigs; Hydroxyquinolines; In Vitro Techniques; Indazoles; Male; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Trachea | 1989 |
Endothelium-dependent relaxation of rat aortic rings by leukotriene D4: importance of the magnitude of preload.
Topics: Acetophenones; Acetylcholine; Animals; Chromones; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; Rats; Rats, Inbred Strains; SRS-A; Tetrazoles; Vasodilation | 1989 |
Effects of 5-lipoxygenase inhibition on cardiac anaphylaxis in isolated guinea pig hearts.
Topics: Acetophenones; Anaphylaxis; Animals; Arachidonate Lipoxygenases; Benzoquinones; Benzyl Compounds; Blood Pressure; Cardiomyopathies; Chromones; Coronary Circulation; Guinea Pigs; Heart; Hydroxamic Acids; Hydroxyquinolines; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Myocardium; Quinolines; Quinones; SRS-A; Tetrazoles | 1989 |
Analysis of leukotriene receptor antagonists on isolated human intralobar airways.
Topics: Acetophenones; Azoles; Barium; Bronchi; Chromones; Humans; Indazoles; Muscle Contraction; Muscle, Smooth; Pyrazoles; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Tetrazoles | 1988 |
A possible role for leukotrienes in the regulation of glomerular haemodynamics in the dog.
Topics: Acetophenones; Animals; Chromones; Dogs; Female; Hemodynamics; Infusions, Intra-Arterial; Kidney Glomerulus; Leukotriene E4; Male; Nephrons; SRS-A; Tetrazoles | 1988 |
A formyl peptide contracts guinea pig lung: role of arachidonic acid metabolites.
Topics: Acetophenones; Animals; Arachidonic Acids; Autacoids; Chromones; Guinea Pigs; Histamine; Leukotriene B4; Lung; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandins; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Tachyphylaxis; Tetrazoles | 1987 |
Systemic and regional hemodynamic effects of leukotrienes D4 and E4 in the conscious rat.
Topics: Acetophenones; Animals; Chromones; Consciousness; Hemodynamics; Leukotriene E4; Male; Rats; Rats, Inbred Strains; SRS-A; Tetrazoles | 1986 |
Involvement of 5-lipoxygenase pathway in norepinephrine stimulation of rat pineal melatonin synthesis.
Topics: Acetophenones; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Chromones; Hydroxyeicosatetraenoic Acids; Lipoxygenase Inhibitors; Male; Masoprocol; Melatonin; Norepinephrine; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; SRS-A; Tetrazoles | 1987 |
Effect of leukotriene C4 exposure on ciliated cells of the nasal mucosa.
Topics: Acetophenones; Adult; Borates; Cells, Cultured; Chromones; Cilia; Culture Media; gamma-Glutamyltransferase; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Nasal Mucosa; Receptors, Leukotriene; Serine; Tetrazoles | 1996 |
Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives.
Topics: Acetophenones; Alkylation; Animals; Bronchi; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship | 1987 |