ly 134046 has been researched along with 1,2,3,4-tetrahydroisoquinoline in 3 studies
| Studies (ly 134046) | Trials (ly 134046) | Recent Studies (post-2010) (ly 134046) | Studies (1,2,3,4-tetrahydroisoquinoline) | Trials (1,2,3,4-tetrahydroisoquinoline) | Recent Studies (post-2010) (1,2,3,4-tetrahydroisoquinoline) |
|---|---|---|---|---|---|
| 31 | 0 | 0 | 240 | 0 | 76 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caldwell, TM; Criscione, KR; Dahanukar, VH; Grunewald, GL; Jalluri, RK | 1 |
| Caldwell, TM; Criscione, KR; Grunewald, GL; Li, Q | 1 |
| Criscione, KR; Grunewald, GL; McLeish, MJ | 1 |
3 other study(ies) available for ly 134046 and 1,2,3,4-tetrahydroisoquinoline
| Article | Year |
|---|---|
Comparative molecular field analysis (CoMFA) models of phenylethanolamine N-methyltransferase (PNMT) and the alpha2-adrenoceptor: the development of new, highly selective inhibitors of PNMT.
Topics: Enzyme Inhibitors; Models, Chemical; Phenylethanolamine N-Methyltransferase; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship | 1999 |
Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines | 1999 |
Phenylethanolamine N-methyltransferase kinetics: bovine versus recombinant human enzyme.
Topics: Animals; Cattle; Epinephrine; Humans; Kinetics; Models, Molecular; Phenylethanolamine N-Methyltransferase; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2001 |