ly 117018 has been researched along with raloxifene hydrochloride in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 13 (61.90) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Black, LJ; Clemens, JA; Falcone, JF; Jevnikar, MG; Jones, CD; Peters, MK; Pike, AJ; Thompson, AR | 1 |
| Boundy, V; Komm, BS; Lyttle, CR; Sundstrom, SA; Xu, Q | 1 |
| Jordan, VC | 1 |
| Green, LR; Newboult, E; Valcaccia, B; Wakeling, AE | 1 |
| Valcaccia, B; Wakeling, AE | 1 |
| Bryan, N; Zuckerman, SH | 1 |
| Bernardi, F; Genazzani, AD; Genazzani, AR; Giardina, L; Luisi, M; Luisi, S; Monteleone, P; Petraglia, F; Rubino, S; Stomati, M | 1 |
| Berg, DT; Calnek, DS; Ciaccia, AV; Grinnell, BW; Joyce, DE; Richardson, MA | 1 |
| Bernardi, F; Casarosa, E; Farzati, A; Genazzani, AR; Luisi, M; Luisi, S; Monteleone, P; Petraglia, F; Rubino, S; Stomati, M | 1 |
| Carlsten, H; Erlandsson, MC; Gömöri, E; Taube, M | 1 |
| Adachi, K; Hayakawa, J; Hisamoto, K; Kanda, Y; Mabuchi, S; Miyamoto, Y; Murata, Y; Nishio, Y; Ohmichi, M; Takahashi, K; Taniguchi, N; Tasaka, K | 1 |
| Islamov, R; McMurray, R; Murashov, AK | 1 |
| Balaguer, P; Bonnet, S; Cavaillès, V; Duong, V; Escande, A; Margueron, R; Vignon, F | 1 |
| Barone, G; Bollati, A; Bonfanti, C; Burattin, A; Cozzi, R; Giustina, A; Poiesi, C; Tulipano, G; Turazzi, S; Valle, D | 1 |
| Aknin, C; Chalbos, D; Freiss, G; Galtier, F; Maudelonde, T; Puech, C; Vignon, F | 1 |
| Benjamins, JA; Deighton-Collins, S; Guzmán, CB; Kleerekoper, M; Martinez, A; Skafar, DF; Zhao, C | 1 |
| Clarke, R; Dai, P; Lou, MA; Lu, JF; Nazarov, V; Wong, LJ | 1 |
| Carlsten, H; Islander, U; Jochems, C; Kallkopf, A; Lagerquist, M; Ohlsson, C | 1 |
| Akishita, M; Eto, M; Kozaki, K; Okabe, T; Ouchi, Y; Yu, J | 1 |
| Carlsten, H; Engdahl, C; Gustafsson, JA; Jochems, C; Lagerquist, MK; van der Saag, PT | 1 |
| Abe, Y; Irie, T; Iwasaki, N; Komatsu, M; Majima, T; Minami, A; Takahata, M | 1 |
1 review(s) available for ly 117018 and raloxifene hydrochloride
| Article | Year |
|---|---|
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes | 1983 |
20 other study(ies) available for ly 117018 and raloxifene hydrochloride
| Article | Year |
|---|---|
Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]-phenyl]methanone hydrochloride (LY156758), a remarkably effec
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Structure-Activity Relationship; Uterus | 1984 |
The stimulation of uterine complement component C3 gene expression by antiestrogens.
Topics: Animals; Complement C3; Drug Interactions; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation; Kinetics; Nucleic Acid Hybridization; Piperidines; Progesterone; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; RNA, Messenger; Tamoxifen; Thiophenes; Uterus | 1990 |
Non-steroidal antioestrogens--receptor binding and biological response in rat uterus, rat mammary carcinoma and human breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Uterus | 1984 |
Antioestrogenic and antitumour activities of a series of non-steroidal antioestrogens.
Topics: Animals; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Organ Size; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen; Thiophenes; Uterus | 1983 |
Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL).
Topics: Animals; Antioxidants; Copper; Dexamethasone; Estradiol; Estrogen Antagonists; Free Radicals; Horseradish Peroxidase; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Peroxidase; Phagocytosis; Piperidines; Probucol; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Thiobarbituric Acid Reactive Substances; Thiophenes; Tyrosine | 1996 |
Raloxifene analog LY 117018 effects on central and peripheral beta-endorphin.
Topics: Animals; beta-Endorphin; Estradiol; Estrogen Antagonists; Female; Hippocampus; Hypothalamus; Nervous System; Ovariectomy; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thiophenes | 1999 |
17beta-estradiol, but not raloxifene, decreases thrombomodulin in the antithrombotic protein C pathway.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Humans; Protein C; Pyrrolidines; Raloxifene Hydrochloride; Thiophenes; Thrombomodulin; Thrombosis; Umbilical Veins | 2000 |
Effects of estradiol and raloxifene analog on brain, adrenal and serum allopregnanolone content in fertile and ovariectomized female rats.
Topics: Adrenal Glands; Animals; Brain; Drug Combinations; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Fertility; Hippocampus; Hypothalamus; Ovariectomy; Pituitary Gland; Pregnanolone; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thiophenes | 2000 |
Effects of raloxifene, a selective estrogen receptor modulator, on thymus, T cell reactivity, and inflammation in mice.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Estradiol; Estrogen Antagonists; Female; Hypersensitivity, Delayed; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, SCID; Molecular Structure; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Thymus Gland | 2000 |
Induction of endothelial nitric-oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells.
Topics: Animals; Cell Line, Transformed; Cells, Cultured; CHO Cells; Cricetinae; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flavonoids; Fulvestrant; Humans; Lung; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estradiol; Thiophenes; Time Factors; Umbilical Veins | 2001 |
Raloxifene analog LY117018 enhances the regeneration of sciatic nerve in ovariectomized female mice.
Topics: Animals; Estrogen Antagonists; Female; Histological Techniques; Mice; Mice, Inbred ICR; Nerve Regeneration; Ovariectomy; Pyrrolidines; Raloxifene Hydrochloride; Sciatic Nerve; Selective Estrogen Receptor Modulators; Thiophenes; Time Factors | 2003 |
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens.
Topics: Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Fulvestrant; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Pyrrolidines; Raloxifene Hydrochloride; Response Elements; Tamoxifen; Thiophenes; Transcription, Genetic; Tumor Cells, Cultured | 2004 |
Effects of the selective estrogen receptor modulator LY117018 on growth hormone secretion: In vitro studies.
Topics: Adenoma; Adult; Aged; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Middle Aged; Pituitary Gland; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Secretory Rate; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes | 2004 |
Anti-growth factor activities of benzothiophenes in human breast cancer cells.
Topics: Breast Neoplasms; Cell Proliferation; Estrogen Antagonists; Humans; Insulin-Like Growth Factor I; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Transcription Factor AP-1; Transcription, Genetic | 2005 |
Activity of estradiol and selective estrogen receptor modulators in the mouse N20.1 oligodendrocyte/astrocytes cell line.
Topics: Animals; Astrocytes; Blotting, Western; Cell Line; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; Ligands; Luciferases; Mice; Neuroglia; Oligodendroglia; Plasmids; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Transfection | 2005 |
AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines.
Topics: Acetyltransferases; Alleles; Breast Neoplasms; Cell Line, Tumor; Cloning, Molecular; Drug Resistance, Neoplasm; Estradiol; Fulvestrant; Histone Acetyltransferases; Humans; Nuclear Receptor Coactivator 3; Oncogene Proteins; Peptides; Polymerase Chain Reaction; Pyrrolidines; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Selective Estrogen Receptor Modulators; Sequence Analysis, DNA; Tamoxifen; Thiophenes; Trans-Activators | 2006 |
Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and osteoporosis.
Topics: Animals; Arthritis; Arthritis, Experimental; Bone Density; Cytokines; Female; Humans; Mice; Osteoporosis, Postmenopausal; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Thiophenes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2007 |
Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway.
Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidants; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Thiophenes | 2008 |
In vivo activation of gene transcription via oestrogen response elements by a raloxifene analogue.
Topics: Animals; Bone Density; Estradiol; Estrogen Antagonists; Estrogens; Female; Femur; Luciferases; Mice; Mice, Inbred CBA; Mice, Transgenic; Organ Size; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Response Elements; Thiophenes; Thymus Gland; Transcription, Genetic; Uterus | 2009 |
Effect of selective estrogen receptor modulator/raloxifene analogue on proliferation and collagen metabolism of tendon fibroblast.
Topics: Achilles Tendon; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cells, Cultured; Collagen Type I; Collagen Type III; Elastin; Estradiol; Estrogen Antagonists; Extracellular Matrix; Female; Fibroblasts; Fulvestrant; Matrix Metalloproteinase 13; Pyrrolidines; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators; Tetrazolium Salts; Thiophenes | 2010 |