ly 117018 has been researched along with afimoxifene in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballejo, G; Gong, Y; Murphy, LC; Murphy, LJ | 1 |
| Koga, M; Sutherland, RL | 2 |
| Dickson, RB; Katz, D; Lippman, ME; Shima, TB; Thompson, EW; Wakeling, AE | 1 |
| Katzenellenbogen, BS; Toney, TW | 1 |
| Crastes de Paulet, A; Cypriani, B; Descomps, B; Tabacik, C | 1 |
| Campen, CA; Gorski, J; Jordan, VC | 1 |
| Bronzert, DA; Greene, GL; Lippman, ME | 1 |
| Jordan, VC | 1 |
| Green, LR; Newboult, E; Valcaccia, B; Wakeling, AE | 1 |
| Gosden, B; Jordan, VC | 2 |
| Jordan, VC; Mueller, GC; Olsen, MR; Tate, AC; Van Oosbree, TR | 1 |
| Borras, M; Bouhoute, A; Jin, L; Leclercq, G; Legros, N | 1 |
| Berthois, Y; Crastes de Paulet, A; Dussert, C; Martin, PM; Pons, M | 1 |
| Balaguer, P; Bonnet, S; Cavaillès, V; Duong, V; Escande, A; Margueron, R; Vignon, F | 1 |
| Body, JJ; Journé, F; Laurent, G; Leclercq, G; Nonclercq, D | 1 |
| Benjamins, JA; Deighton-Collins, S; Guzmán, CB; Kleerekoper, M; Martinez, A; Skafar, DF; Zhao, C | 1 |
| Clarke, R; Dai, P; Lou, MA; Lu, JF; Nazarov, V; Wong, LJ | 1 |
1 review(s) available for ly 117018 and afimoxifene
| Article | Year |
|---|---|
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes | 1983 |
18 other study(ies) available for ly 117018 and afimoxifene
| Article | Year |
|---|---|
Differential effects of estrogen and antiestrogen on transforming growth factor gene expression in endometrial adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Cell Division; Cell Line; Dose-Response Relationship, Drug; Endometrial Neoplasms; ErbB Receptors; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Kinetics; Polyunsaturated Alkamides; Pyrrolidines; RNA, Messenger; Tamoxifen; Thiophenes; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1992 |
Retinoic acid acts synergistically with 1,25-dihydroxyvitamin D3 or antioestrogen to inhibit T-47D human breast cancer cell proliferation.
Topics: Breast Neoplasms; Calcitriol; Cell Division; Cell Line; Clomiphene; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Pyrrolidines; Receptors, Calcitriol; Receptors, Estradiol; Receptors, Steroid; Tamoxifen; Thiophenes; Tretinoin | 1991 |
ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness.
Topics: Basement Membrane; Binding, Competitive; Breast Neoplasms; Cell Cycle; Estradiol; Estrogen Antagonists; Humans; Neoplasm Invasiveness; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Estrogen; Stimulation, Chemical; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 1989 |
An evaluation of the interactions of antiestrogens with pituitary and striatal dopamine receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Diethylamines; Estrogen Antagonists; Female; Nitromifene; Pituitary Gland, Anterior; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tamoxifen; Thiophenes | 1987 |
Role of estrogen receptors and antiestrogen binding sites in an early effect of antiestrogens, the inhibition of cholesterol biosynthesis.
Topics: Animals; Binding Sites; Cell Division; Cell Line; Cholesterol; Humans; Molecular Weight; Pyrrolidines; Rats; Receptors, Drug; Receptors, Estrogen; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 1988 |
Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth.
Topics: Breast Neoplasms; Cell Division; Cell Line; Clomiphene; Epidermal Growth Factor; Estrogen Antagonists; Humans; Pyrrolidines; Tamoxifen; Thiophenes | 1987 |
Opposing biological actions of antiestrogens in vitro and in vivo: induction of progesterone receptor in the rat and mouse uterus.
Topics: Animals; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; In Vitro Techniques; Mice; Mice, Inbred ICR; Pyrrolidines; Rats; Receptors, Progesterone; Species Specificity; Stereoisomerism; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus | 1985 |
Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Drug Resistance; Estradiol; Female; Humans; Molecular Weight; Phenotype; Pyrrolidines; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Thiophenes | 1985 |
Non-steroidal antioestrogens--receptor binding and biological response in rat uterus, rat mammary carcinoma and human breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Uterus | 1984 |
Differential antiestrogen action in the immature rat uterus: a comparison of hydroxylated antiestrogens with high affinity for the estrogen receptor.
Topics: Animals; Binding, Competitive; Estrogen Antagonists; Female; Kinetics; Organ Size; Promegestone; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sexual Maturation; Tamoxifen; Thiophenes; Uterus | 1983 |
An immobilized antiestrogen binds a specific uterine protein in addition to estrogen receptor proteins.
Topics: Agar; Animals; Carrier Proteins; Cytosol; Estrogen Antagonists; Female; Molecular Weight; Pyrrolidines; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Uterus | 1984 |
Inhibition of the uterotropic activity of estrogens and antiestrogens by the short acting antiestrogen LY117018.
Topics: Animals; Castration; Estradiol; Estrogen Antagonists; Female; Mice; Organ Size; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus | 1983 |
Evaluation of estrogen receptor, antiestrogen binding sites and calmodulin for antiestrogen resistance of two clones derived from the MCF-7 breast cancer cell line.
Topics: Binding Sites; Calmodulin; Cell Division; Clone Cells; Drug Resistance; Estrogen Antagonists; Humans; Imidazoles; Pyrrolidines; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 1994 |
Agonist-antagonist activity of anti-estrogens in the human breast cancer cell line MCF-7: an hypothesis for the interaction with a site distinct from the estrogen binding site.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Cell Fractionation; Centrifugation, Density Gradient; Cytosol; Estradiol; Estrogen Antagonists; Humans; Pyrrolidines; Receptors, Estrogen; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 1994 |
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens.
Topics: Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Fulvestrant; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Pyrrolidines; Raloxifene Hydrochloride; Response Elements; Tamoxifen; Thiophenes; Transcription, Genetic; Tumor Cells, Cultured | 2004 |
Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathways.
Topics: Breast Neoplasms; Cycloheximide; Enzyme Inhibitors; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Immunoenzyme Techniques; Lactones; Leupeptins; Ligands; Macrolides; Molecular Chaperones; Proteasome Inhibitors; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyrrolidines; Signal Transduction; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 2004 |
Activity of estradiol and selective estrogen receptor modulators in the mouse N20.1 oligodendrocyte/astrocytes cell line.
Topics: Animals; Astrocytes; Blotting, Western; Cell Line; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; Ligands; Luciferases; Mice; Neuroglia; Oligodendroglia; Plasmids; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Transfection | 2005 |
AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines.
Topics: Acetyltransferases; Alleles; Breast Neoplasms; Cell Line, Tumor; Cloning, Molecular; Drug Resistance, Neoplasm; Estradiol; Fulvestrant; Histone Acetyltransferases; Humans; Nuclear Receptor Coactivator 3; Oncogene Proteins; Peptides; Polymerase Chain Reaction; Pyrrolidines; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Selective Estrogen Receptor Modulators; Sequence Analysis, DNA; Tamoxifen; Thiophenes; Trans-Activators | 2006 |