luzindole has been researched along with colforsin in 16 studies
| Studies (luzindole) | Trials (luzindole) | Recent Studies (post-2010) (luzindole) | Studies (colforsin) | Trials (colforsin) | Recent Studies (post-2010) (colforsin) |
|---|---|---|---|---|---|
| 265 | 1 | 119 | 13,460 | 46 | 1,298 |
| Protein | Taxonomy | luzindole (IC50) | colforsin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 1.729 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.041 | |
| Adenylate cyclase type 1 | Homo sapiens (human) | 0.0955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gan, J; Iuvone, PM | 1 |
| Dubocovich, ML; Witt-Enderby, PA | 1 |
| Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD | 1 |
| Flanders, S; Lew, MJ | 1 |
| Calvo, JR; García-Pergañeda, A; Guerrero, JM; Paz Romero, M; Pozo, D; Rafii-El-Idrissi, M | 1 |
| Beckmann, A; Fauteck, JD; Musshoff, U; Peschke, D; Peschke, E; Schmidt, F | 1 |
| Markowska, M; Mrozkowiak, A; Skwarlo-Sonta, K | 1 |
| Chankiewitz, E; Csernus, VJ; Mühlbauer, E; Musshoff, U; Peschke, D; Peschke, E | 1 |
| Markowska, M; Mrozkowiak, A; Pawlak, J; Skwarło-Sońta, K | 1 |
| Alonso-Vale, MI; Andreotti, S; Anhê, GF; das Neves Borges-Silva, C; Lima, FB; Neto, JC; Peres, SB | 1 |
| Mühlbauer, E; Peschke, E; Stumpf, I | 1 |
| Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K | 1 |
| Sampaio, Lde F | 1 |
| Guerra, M; Pedreros, M; Ratto, M | 1 |
| Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Hirai, K; Nishiyama, K | 1 |
16 other study(ies) available for luzindole and colforsin
| Article | Year |
|---|---|
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Characterization and regulation of the human ML1A melatonin receptor stably expressed in Chinese hamster ovary cells.
Topics: Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Kinetics; Melatonin; Receptors, Cell Surface; Receptors, Melatonin; Recombinant Proteins; Transfection; Tryptamines | 1996 |
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines | 1997 |
Mechanisms of melatonin-induced vasoconstriction in the rat tail artery: a paradigm of weak vasoconstriction.
Topics: Acetamides; Animals; Anticonvulsants; Arteries; Calcium Channel Blockers; Charybdotoxin; Colforsin; Dose-Response Relationship, Drug; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Male; Melatonin; Nifedipine; Nitroprusside; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tryptamines; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1999 |
Characterization of membrane melatonin receptor in mouse peritoneal macrophages: inhibition of adenylyl cyclase by a pertussis toxin-sensitive G protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Blotting, Western; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Iodine Radioisotopes; Kinetics; Macrophages, Peritoneal; Melatonin; Mice; Neuroimmunomodulation; Pertussis Toxin; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Signal Transduction; Tryptamines; Virulence Factors, Bordetella | 1999 |
Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations.
Topics: Animals; Animals, Newborn; Autoradiography; Colforsin; DNA Primers; Dose-Response Relationship, Drug; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Insulin Secretion; Islets of Langerhans; Male; Melatonin; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tryptamines | 2000 |
Influence of melatonin on chicken lymphocytes in vitro: involvement of membrane receptors.
Topics: Animals; Antioxidants; Cell Division; Cell Membrane; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Lymphocytes; Male; Melatonin; Phytohemagglutinins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Spleen; Tryptamines | 2002 |
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Melatonin; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; Probenecid; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Tryptamines; Tumor Cells, Cultured | 2002 |
Intracellular second messengers involved in melatonin signal transduction in chicken splenocytes in vitro.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Male; Melatonin; Receptor, Melatonin, MT2; Receptors, Melatonin; Second Messenger Systems; Signal Transduction; Spleen; Tetrahydronaphthalenes; Tryptamines | 2004 |
Melatonin enhances leptin expression by rat adipocytes in the presence of insulin.
Topics: Adipocytes; Animals; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Glucocorticoids; Inhibitory Concentration 50; Insulin; Leptin; Male; Melatonin; Pertussis Toxin; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Receptor, Melatonin, MT1; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tryptamines | 2005 |
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines | 2008 |
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines | 2008 |
An unexpected effect of 5-MCA-NAT in chick retinal development.
Topics: Aging; Animals; Binding Sites; Chick Embryo; Chickens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Melatonin; Neurogenesis; Neurons; Organ Culture Techniques; Organogenesis; Quinone Reductases; Receptors, G-Protein-Coupled; Receptors, Melatonin; Retina; Second Messenger Systems; Tryptamines; Up-Regulation | 2009 |
Expression of functional melatonin MT(1) receptors in equine luteal cells: in vitro effects of melatonin on progesterone secretion.
Topics: Animals; Blotting, Western; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Colforsin; Female; Horses; Luteal Cells; Melatonin; Ovarian Follicle; Progesterone; Receptor, Melatonin, MT1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tryptamines | 2011 |
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Insulin-Secreting Cells; Insulinoma; Melatonin; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Time Factors; Transfection; Tryptamines | 2012 |
The melatonin agonist ramelteon induces duration-dependent clock gene expression through cAMP signaling in pancreatic INS-1 β-cells.
Topics: Animals; ARNTL Transcription Factors; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Humans; Indenes; Insulin-Secreting Cells; Nuclear Receptor Subfamily 1, Group D, Member 1; Phosphorylation; Rats; Receptors, Melatonin; Tryptamines | 2014 |