Page last updated: 2024-09-03

luzindole and 4-phenyl-2-propionamidotetraline

luzindole has been researched along with 4-phenyl-2-propionamidotetraline in 42 studies

Compound Research Comparison

Studies (luzindole)	Trials (luzindole)	Recent Studies (post-2010) (luzindole)	Studies (4-phenyl-2-propionamidotetraline)	Trials (4-phenyl-2-propionamidotetraline)	Recent Studies (post-2010) (4-phenyl-2-propionamidotetraline)
265	1	119	72	1	29

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (4.76)	18.2507
2000's	22 (52.38)	29.6817
2010's	18 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM	1
Al-Ghoul, WM; Benloucif, S; Dubocovich, ML; Masana, MI; Yun, K	1
Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V	1
Amossé, C; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Dromaint, S; Galizzi, JP; Guillaumet, G; Lahaye-Brasseur, C; Le Gall, A; Lefoulon, F; Lesieur, D; Mailliet, F; Malpaux, B; Nagel, N; Renard, P; Rodriguez, M	1
Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP	1
Al-Ghoul, WM; Dubocovich, ML; Gillette, MU; Hunt, AE	1
Flemström, G; Jedstedt, G; Sjöblom, M	1
Dubocovich, ML; Farsky, SH; Lopes, C; Lotufo, CM; Markus, RP	1
Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J	1
Berger, E; Fauteck, JD; Musshoff, U; Riewenherm, D; Speckmann, EJ	1
Kravtsov, GM; Pang, SF; Poon, AM	1
Dubocovich, ML; Gerdin, MJ; Masana, MI; Miller, RJ; Ren, D	1
Chen, Y; Fung, ML; Ip, SF; Liong, EC; Tipoe, GL; Tjong, YW	1
Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E	1
Anhê, GF; Caperuto, LC; Carvalho, CR; Cipolla-Neto, J; Hirata, AE; Pereira-Da-Silva, M; Souza, LC; Velloso, LA	1
Markowska, M; Mrozkowiak, A; Pawlak, J; Skwarło-Sońta, K	1
Chen, Y; Fung, ML; Ip, SF; Tipoe, GL; Tjong, YW	1
Leung, LS; Stewart, LS	1
Audinot, V; Boutin, JA; Delagrange, P; Ferry, G	1
Mühlbauer, E; Peschke, E; Stumpf, I	1
Chan, KW; Liu, VW; Pang, B; Shiu, SY; Tam, CW; Yao, KM	1
Imbesi, M; Manev, H; Uz, T	1
Fujinoki, M	1
Boutin, JA; Cogé, F; Cohen, W; Delagrange, P; Devavry, S; Fery, I; Guenin, SP; Legros, C; Malpaux, B; Migaud, M; Nosjean, O; Ouvry, C; Renault, N; Slugocki, C	1
Fuss-Chmielewska, J; Karasek, M; Lawnicka, H; Pawlikowski, M; Winczyk, K	1
Cheng, JC; Hung, WY; Lee, SK; Man, GC; Ng, BK; Ng, TB; Qiu, Y; Wang, WW; Wong, JH; Yeung, BH	1
Pang, B; Shiu, SY; Tam, CW; Yao, KM	1
Bambico, FR; Domínguez-López, S; Gobbi, G; Labonté, B; Leyton, M; Mahar, I; Ochoa-Sánchez, R	1
Ahmad, R; Gupta, S; Haldar, C	1
Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S	1
Albrecht, E; Bähr, I; Mühlbauer, E; Peschke, E	1
Bedini, A; Comai, S; Fraschini, F; Gobbi, G; Mor, M; Ochoa-Sanchez, R; Rainer, Q; Rivara, S; Spadoni, G; Tarzia, G	1
Bedrosian, TA; Fonken, LK; Herring, KL; Nelson, RJ; Walton, JC; Weil, ZM	1
Markus, RP; Pires-Lapa, MA; Salustiano, EM; Tamura, EK	1
Fu, Y; Gao, C; He, C; Ji, P; Li, N; Li, Y; Liu, G; Tian, X; Wang, F; Zhang, L	1
Alves, CN; de Sousa, PR; Mesquita, FP; Sampaio, Lde F; Silva, JL	1
Juszczak, M; Kowalczyk, E; Roszczyk, M; Stempniak, B	1
Fonseca, B; Martínez-Águila, A; Pérez de Lara, MJ; Pintor, J	1
Cao, J; Chen, F; Chen, Y; Dong, Y; Reheman, A; Wang, Z; Zhang, Y	1
Barberino, RS; Jiang, X; Matos, MHT; Menezes, VG; Palheta, RC; Ribeiro, AEAS; Smitz, JEJ	1
Deng, SL; Lian, ZX; Liu, YX; Sun, TC; Wang, XX; Wang, ZP; Yu, K; Zhang, BL; Zhang, Y	1
Ikeuchi, T; Sakai, K; Yamamoto, Y	1

Reviews

1 review(s) available for luzindole and 4-phenyl-2-propionamidotetraline

Article	Year
Molecular tools to study melatonin pathways and actions. Trends in pharmacological sciences, 2005, Volume: 26, Issue:8 Topics: Animals; Antioxidants; Humans; Melatonin; Molecular Structure; Receptors, Melatonin; Signal Transduction; Tetrahydronaphthalenes; Tryptamines	2005

Trials

1 trial(s) available for luzindole and 4-phenyl-2-propionamidotetraline

Article	Year
Melatonin synthesis in human colostrum mononuclear cells enhances dectin-1-mediated phagocytosis by mononuclear cells. Journal of pineal research, 2013, Volume: 55, Issue:3 Topics: Adolescent; Adult; Animals; Cell Line; Colostrum; DNA-Binding Proteins; Female; Humans; Infant, Newborn; Lectins, C-Type; Leukocytes, Mononuclear; Melatonin; Mice; Nuclear Proteins; Phagocytosis; Proto-Oncogene Proteins c-rel; Tetrahydronaphthalenes; Transcription Factor RelA; Tryptamines	2013

Article

Year

Melatonin synthesis in human colostrum mononuclear cells enhances dectin-1-mediated phagocytosis by mononuclear cells.

Journal of pineal research, 2013, Volume: 55, Issue:3

Topics: Adolescent; Adult; Animals; Cell Line; Colostrum; DNA-Binding Proteins; Female; Humans; Infant, Newborn; Lectins, C-Type; Leukocytes, Mononuclear; Melatonin; Mice; Nuclear Proteins; Phagocytosis; Proto-Oncogene Proteins c-rel; Tetrahydronaphthalenes; Transcription Factor RelA; Tryptamines

2013

Other Studies

40 other study(ies) available for luzindole and 4-phenyl-2-propionamidotetraline

Article	Year
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:3 Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina	1997
Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:12 Topics: Animals; Base Sequence; CHO Cells; Circadian Rhythm; Cricetinae; Darkness; Humans; Male; Melatonin; Mice; Mice, Inbred C3H; Motor Activity; Oligonucleotides, Antisense; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Transfection; Tryptamines	1998
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation. Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8 Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin	2003
New selective ligands of human cloned melatonin MT1 and MT2 receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:6 Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Humans; Ligands; Melatonin; Protein Binding; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2	2003
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential. Journal of medicinal chemistry, 2014, Apr-24, Volume: 57, Issue:8 Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship	2014
Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock. American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:1 Topics: Action Potentials; Animals; Biological Clocks; Circadian Rhythm; Iodine Radioisotopes; Male; Melatonin; Neurons; Oligoribonucleotides, Antisense; Protein Kinase C; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Suprachiasmatic Nucleus; Tetrahydronaphthalenes; Tryptamines	2001
Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretion. The Journal of clinical investigation, 2001, Volume: 108, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; Bicarbonates; Blood Pressure; Circadian Rhythm; Corticotropin-Releasing Hormone; Duodenum; Enterochromaffin Cells; gamma-MSH; Hypophysectomy; Injections, Intra-Arterial; Injections, Intraventricular; Intestinal Mucosa; Melatonin; Neurosecretion; Phenylephrine; Pineal Gland; Prazosin; Protein Isoforms; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Thiopental; Tryptamines; Vagotomy	2001
Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation. European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3 Topics: Animals; Arterioles; Blood Flow Velocity; Cell Adhesion; Dose-Response Relationship, Drug; Leukocytes; Male; Melatonin; Microcirculation; Rats; Rats, Wistar; Serotonin; Tetrahydronaphthalenes; Tryptamines	2001
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. Annals of neurology, 2002, Volume: 51, Issue:1 Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease Models, Animal; Excitatory Amino Acid Agonists; Free Radical Scavengers; Humans; Hypothermia, Induced; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Melatonin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuroprotective Agents; Neurotoxins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetrahydronaphthalenes; Tryptamines	2002
Melatonin receptors in rat hippocampus: molecular and functional investigations. Hippocampus, 2002, Volume: 12, Issue:2 Topics: Animals; Circadian Rhythm; Electrophysiology; Hippocampus; Male; Melatonin; Membrane Potentials; Oocytes; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tryptamines; Xenopus	2002
Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase. Journal of pineal research, 2002, Volume: 32, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apamin; Binding, Competitive; Cecum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Melatonin; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels; Protein-Tyrosine Kinases; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines	2002
Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3 Topics: Animals; Arrestin; CHO Cells; Cricetinae; Humans; Iodine Radioisotopes; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Transfection; Tryptamines	2003
Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis. Journal of pineal research, 2004, Volume: 36, Issue:1 Topics: Acidosis, Respiratory; Animals; Calcium; Carotid Body; Chemoreceptor Cells; Electrophysiology; Fura-2; Hypercapnia; Melatonin; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines	2004
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi. General and comparative endocrinology, 2004, Volume: 135, Issue:3 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines	2004
In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus. Journal of neurochemistry, 2004, Volume: 90, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Hypothalamus; Injections, Intraventricular; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Male; Melatonin; Mitogen-Activated Protein Kinase 1; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines	2004
Intracellular second messengers involved in melatonin signal transduction in chicken splenocytes in vitro. Journal of pineal research, 2004, Volume: 37, Issue:3 Topics: Animals; Cell Proliferation; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Male; Melatonin; Receptor, Melatonin, MT2; Receptors, Melatonin; Second Messenger Systems; Signal Transduction; Spleen; Tetrahydronaphthalenes; Tryptamines	2004
Melatonin enhances the hypoxic response of rat carotid body chemoreceptor. Journal of pineal research, 2005, Volume: 38, Issue:3 Topics: Animals; Calcium; Carotid Body; Chemoreceptor Cells; Circadian Rhythm; Hypoxia; In Vitro Techniques; Melatonin; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Respiration; Tetrahydronaphthalenes; Tryptamines	2005
Hippocampal melatonin receptors modulate seizure threshold. Epilepsia, 2005, Volume: 46, Issue:4 Topics: Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Exploratory Behavior; Functional Laterality; GABA Antagonists; Hippocampus; Locomotion; Male; Muscimol; Pilocarpine; Rats; Rats, Wistar; Receptors, Melatonin; Seizures; Tetrahydronaphthalenes; Tryptamines	2005
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells. Journal of pineal research, 2008, Volume: 45, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines	2008
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance. Journal of pineal research, 2008, Volume: 45, Issue:4 Topics: Analysis of Variance; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Gene Expression Regulation; Growth Substances; Humans; Immunoblotting; Immunohistochemistry; Male; Melatonin; Prostate; Prostatic Neoplasms; Protein Kinases; Receptors, Androgen; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrahydronaphthalenes; Tryptamines	2008
Melatonin receptor agonist ramelteon activates the extracellular signal-regulated kinase 1/2 in mouse cerebellar granule cells. Neuroscience, 2008, Sep-09, Volume: 155, Issue:4 Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Enzyme Activation; Indenes; Mice; Mice, Inbred C3H; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines	2008
Melatonin-enhanced hyperactivation of hamster sperm. Reproduction (Cambridge, England), 2008, Volume: 136, Issue:5 Topics: Animals; Calcium; Cells, Cultured; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serum Albumin; Sperm Motility; Spermatozoa; Stimulation, Chemical; Tetrahydronaphthalenes; Time; Tryptamines	2008
The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor. British journal of pharmacology, 2009, Volume: 158, Issue:5 Topics: Amino Acid Sequence; Animals; Brain; Cattle; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Female; GTP-Binding Proteins; Humans; Molecular Sequence Data; Organ Specificity; Radioligand Assay; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Recombinant Proteins; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Sheep; Tetrahydronaphthalenes; Tryptamines	2009
Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro. Neuro endocrinology letters, 2009, Volume: 30, Issue:5 Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Humans; Melatonin; Mice; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines	2009
Abnormal proliferation and differentiation of osteoblasts from girls with adolescent idiopathic scoliosis to melatonin. Journal of pineal research, 2010, Volume: 49, Issue:1 Topics: Adolescent; Adult; Alkaline Phosphatase; Analysis of Variance; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Male; Melatonin; Osteoblasts; Photomicrography; Receptor, Melatonin, MT2; Scoliosis; Tetrahydronaphthalenes; Tryptamines	2010
Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα(s) and Gα(q) proteins. Journal of pineal research, 2010, Volume: 49, Issue:3 Topics: Antioxidants; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Human papillomavirus 18; Humans; Melatonin; Radioimmunoassay; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tetrahydronaphthalenes; Tryptamines	2010
Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle. Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:6 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Idazoxan; Male; Melatonin; Mood Disorders; Neurons; Photoperiod; Pineal Gland; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Synaptic Transmission; Tetrahydronaphthalenes; Tryptamines	2012
Melatonin membrane receptor type MT1 modulates cell-mediated immunity in the seasonally breeding tropical rodent Funambulus pennanti. Neuroimmunomodulation, 2012, Volume: 19, Issue:1 Topics: Analysis of Variance; Animals; Breeding; Cell Proliferation; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Drug; Gene Expression Regulation; Immunity; In Vitro Techniques; Interleukin-2; Lymphocytes; Male; Melatonin; Mitogens; Random Allocation; Receptor, Melatonin, MT1; Sciuridae; Seasons; Spleen; Tetrahydronaphthalenes; Tryptamines	2012
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1). Journal of pineal research, 2012, Volume: 53, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Insulin-Secreting Cells; Insulinoma; Melatonin; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Time Factors; Transfection; Tryptamines	2012
Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways. Journal of pineal research, 2012, Volume: 53, Issue:4 Topics: Animals; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; GTP-Binding Protein alpha Subunits, Gq-G11; Liver; Male; Melanins; Mice; Mice, Knockout; Pertussis Toxin; Phosphatidylinositol 3-Kinase; Rats; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Glucagon; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Tissue Culture Techniques; Tryptamines; Type C Phospholipases	2012
Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam. Progress in neuro-psychopharmacology & biological psychiatry, 2012, Dec-03, Volume: 39, Issue:2 Topics: Acetamides; Aniline Compounds; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Partial Agonism; Feeding Behavior; Male; Maze Learning; Melatonin; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines	2012
Evidence for feedback control of pineal melatonin secretion. Neuroscience letters, 2013, May-10, Volume: 542 Topics: Animals; Darkness; Feedback, Physiological; Female; Melatonin; Peromyscus; Pineal Gland; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines	2013
Beneficial effects of melatonin on in vitro bovine embryonic development are mediated by melatonin receptor 1. Journal of pineal research, 2014, Volume: 56, Issue:3 Topics: Animals; Blastocyst; Cattle; Embryonic Development; Glutathione Peroxidase; Melatonin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Superoxide Dismutase; Superoxide Dismutase-1; Tetrahydronaphthalenes; Tryptamines	2014
The melatonin analog 5-MCA-NAT increases endogenous dopamine levels by binding NRH:quinone reductase enzyme in the developing chick retina. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2014, Volume: 38 Topics: Age Factors; Animals; Animals, Newborn; Chick Embryo; Chickens; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Developmental; Models, Molecular; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); Protein Binding; Receptor, Melatonin, MT2; Retina; Tetrahydronaphthalenes; Tryptamines	2014
The influence od melatonin receptors antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT), on melatonin-dependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophysial system. In vitro and in vivo Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:6 Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Hypothalamo-Hypophyseal System; Male; Melatonin; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines; Vasopressins	2014
Effect of Melatonin and 5-Methoxycarbonylamino-N-Acetyltryptamine on the Intraocular Pressure of Normal and Glaucomatous Mice. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Glaucoma; Intraocular Pressure; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines	2016
Effect of melatonin on monochromatic light-induced T-lymphocyte proliferation in the thymus of chickens. Journal of photochemistry and photobiology. B, Biology, 2016, Volume: 161 Topics: Animals; Cell Proliferation; Cells, Cultured; Chickens; Concanavalin A; Gene Expression; Immunohistochemistry; Light; Male; Melatonin; Prazosin; Proliferating Cell Nuclear Antigen; Receptors, Melatonin; RNA, Messenger; T-Lymphocytes; Tetrahydronaphthalenes; Thymus Gland; Tryptamines	2016
Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxidant activity. Biology of reproduction, 2017, Jun-01, Volume: 96, Issue:6 Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Melatonin; Mice; Ovary; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines	2017
Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen. Free radical biology & medicine, 2017, Volume: 113 Topics: Adenosine Triphosphate; Antioxidants; Benzoquinones; Cell Survival; Cryopreservation; Cryoprotective Agents; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lipid Peroxidation; Male; Melatonin; NF-E2-Related Factor 2; Oxidative Stress; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptor, Melatonin, MT1; Semen; Semen Analysis; Sperm Motility; Tetrahydronaphthalenes; Tryptamines	2017
Vertebrates originally possess four functional subtypes of G protein-coupled melatonin receptor. Scientific reports, 2019, 07-01, Volume: 9, Issue:1 Topics: Animals; Brain; Down-Regulation; Eye; Melatonin; Oryzias; Phylogeny; Pituitary Gland; Receptors, Melatonin; Synteny; Tetrahydronaphthalenes; Tryptamines; Vertebrates	2019