luzindole has been researched along with 2-iodomelatonin in 20 studies
| Studies (luzindole) | Trials (luzindole) | Recent Studies (post-2010) (luzindole) | Studies (2-iodomelatonin) | Trials (2-iodomelatonin) | Recent Studies (post-2010) (2-iodomelatonin) |
|---|---|---|---|---|---|
| 265 | 1 | 119 | 245 | 0 | 10 |
| Protein | Taxonomy | luzindole (IC50) | 2-iodomelatonin (IC50) |
|---|---|---|---|
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 1.1 | |
| Melatonin receptor type 1A | Homo sapiens (human) | 0.0005 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM | 1 |
| Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V | 1 |
| Amossé, C; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Dromaint, S; Galizzi, JP; Guillaumet, G; Lahaye-Brasseur, C; Le Gall, A; Lefoulon, F; Lesieur, D; Mailliet, F; Malpaux, B; Nagel, N; Renard, P; Rodriguez, M | 1 |
| Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP | 1 |
| Dubocovich, ML | 1 |
| Gan, J; Iuvone, PM | 1 |
| Chong, NW; Sugden, D | 1 |
| Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD | 1 |
| Bucher, B; Gauer, F; Masson-Pévet, M; Pévet, P | 1 |
| Flanders, S; Lew, MJ | 1 |
| Angeloni, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Stankov, BM | 1 |
| Barrett, P; Conway, S; Delagrange, P; Drew, JE; Morgan, PJ; Mowat, ES | 1 |
| Alonso-Bedate, M; Alonso-Gómez, AL; De Pedro, N; Delgado, MJ; Pinillos, ML | 1 |
| Kravtsov, GM; Pang, SF; Poon, AM | 1 |
| Castrucci, AM; Souza, AV; Visconti, MA | 1 |
| Chen, Y; Fung, ML; Ip, SF; Liong, EC; Tipoe, GL; Tjong, YW | 1 |
| Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E | 1 |
| Chen, Y; Fung, ML; Ip, SF; Tipoe, GL; Tjong, YW | 1 |
| Chan, KW; Liu, VW; Pang, B; Shiu, SY; Tam, CW; Yao, KM | 1 |
| Fujinoki, M | 1 |
1 review(s) available for luzindole and 2-iodomelatonin
| Article | Year |
|---|---|
Melatonin receptors in the central nervous system.
Topics: Animals; Brain Chemistry; Calcium; Chickens; Circadian Rhythm; Dopamine; Hypothalamus; Mammals; Melatonin; Mice; Mice, Inbred C3H; Periodicity; Pineal Gland; Receptors, Melatonin; Receptors, Neurotransmitter; Reproduction; Retina; Seasons; Suprachiasmatic Nucleus; Tryptamines | 1991 |
19 other study(ies) available for luzindole and 2-iodomelatonin
| Article | Year |
|---|---|
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina | 1997 |
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin | 2003 |
New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Humans; Ligands; Melatonin; Protein Binding; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2 | 2003 |
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Thermodynamic analysis of agonist and antagonist binding to the chicken brain melatonin receptor.
Topics: Animals; Binding Sites; Brain; Chickens; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Melatonin; Receptors, Cell Surface; Receptors, Melatonin; Regression Analysis; Temperature; Thermodynamics; Tryptamines | 1994 |
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines | 1997 |
Vasoconstrictor effects of various melatonin analogs on the rat tail artery in the presence of phenylephrine.
Topics: Acetamides; Animals; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Male; Melatonin; Muscle, Smooth; Nerve Endings; Norepinephrine; Perfusion; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Tail; Tryptamines; Vasoconstriction | 1999 |
Mechanisms of melatonin-induced vasoconstriction in the rat tail artery: a paradigm of weak vasoconstriction.
Topics: Acetamides; Animals; Anticonvulsants; Arteries; Calcium Channel Blockers; Charybdotoxin; Colforsin; Dose-Response Relationship, Drug; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Male; Melatonin; Nifedipine; Nitroprusside; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tryptamines; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1999 |
Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonists.
Topics: 3T3 Cells; Animals; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Melatonin; Mice; Pertussis Toxin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Proteins; Tryptamines; Virulence Factors, Bordetella | 1999 |
Serine residues 110 and 114 are required for agonist binding but not antagonist binding to the melatonin MT(1) receptor.
Topics: Acetamides; Amides; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Heterotrimeric GTP-Binding Proteins; Humans; Indoles; Melatonin; Mutagenesis, Site-Directed; Naphthalenes; Protein Binding; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Transfection; Tryptamines | 2001 |
Food intake inhibition by melatonin in goldfish (Carassius auratus).
Topics: Animals; Antioxidants; Depression, Chemical; Eating; Goldfish; Injections, Intraperitoneal; Injections, Intraventricular; Melatonin; Tryptamines | 2001 |
Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apamin; Binding, Competitive; Cecum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Melatonin; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels; Protein-Tyrosine Kinases; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines | 2002 |
Melatonin biological activity and binding sites in human melanoma cells.
Topics: Binding Sites; Binding, Competitive; Cell Division; Humans; Iodine Radioisotopes; Melanoma; Melatonin; Monophenol Monooxygenase; Prazosin; Serotonin; Tryptamines; Tumor Cells, Cultured | 2003 |
Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis.
Topics: Acidosis, Respiratory; Animals; Calcium; Carotid Body; Chemoreceptor Cells; Electrophysiology; Fura-2; Hypercapnia; Melatonin; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines | 2004 |
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines | 2004 |
Melatonin enhances the hypoxic response of rat carotid body chemoreceptor.
Topics: Animals; Calcium; Carotid Body; Chemoreceptor Cells; Circadian Rhythm; Hypoxia; In Vitro Techniques; Melatonin; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Respiration; Tetrahydronaphthalenes; Tryptamines | 2005 |
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance.
Topics: Analysis of Variance; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Gene Expression Regulation; Growth Substances; Humans; Immunoblotting; Immunohistochemistry; Male; Melatonin; Prostate; Prostatic Neoplasms; Protein Kinases; Receptors, Androgen; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrahydronaphthalenes; Tryptamines | 2008 |
Melatonin-enhanced hyperactivation of hamster sperm.
Topics: Animals; Calcium; Cells, Cultured; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serum Albumin; Sperm Motility; Spermatozoa; Stimulation, Chemical; Tetrahydronaphthalenes; Time; Tryptamines | 2008 |