Page last updated: 2024-09-05

lutein and eicosapentaenoic acid

lutein has been researched along with eicosapentaenoic acid in 27 studies

Compound Research Comparison

Studies
(lutein)
Trials
(lutein)
Recent Studies (post-2010)
(lutein)
Studies
(eicosapentaenoic acid)
Trials
(eicosapentaenoic acid)
Recent Studies (post-2010) (eicosapentaenoic acid)
2,7702671,4227,1711,3043,623

Protein Interaction Comparison

ProteinTaxonomylutein (IC50)eicosapentaenoic acid (IC50)
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))Homo sapiens (human)4
Prostaglandin G/H synthase 2Ovis aries (sheep)7.1
Oxoeicosanoid receptor 1Homo sapiens (human)2

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (14.81)29.6817
2010's19 (70.37)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Ghadirian, P; Nkondjock, A1
Klasing, KC; Selvaraj, RK1
Chiu, CJ; Gensler, G; Klein, R; Milton, RC; Taylor, A1
Chen, F; Huangfu, J; Jiang, Y; Liu, J; Sun, Z; Wang, M; Zeng, X1
Chew, EY; Clemons, T; Danis, R; Domalpally, A; Ferris, FL; McBee, W; SanGiovanni, JP; Sperduto, R1
Arnold, C; Böhm, V; Dawczynski, J; Fröhlich, K; Jahreis, G; Jentsch, S; Winter, L1
Inaba, T; Kawakita, T; Kawashima, M; Nakamura, S; Ozawa, Y; Shinmura, K; Tsubota, K; Watanabe, M1
Cao, X; Chan, CC; Chew, EY; Ramkumar, HL; Shen, DF; Tuo, J; Zhang, J1
Beatty, S; Meagher, KA; Nolan, JM1
Arnold, C; Böhm, V; Jentsch, S; Schweitzer, D1
Chen, CN; Chuang, LT; Tsai, HP1
Gill, SS; Seitz, DP1
Agrón, E; Bernstein, PS; Chew, EY; Clemons, TE; Grodstein, F; Launer, LJ1
Fischer, T1
Hammond, BR; Miller, LS; Renzi-Hammond, LM1
Nelson, E; Salem, N; Yurko-Mauro, K1
Bernstein, P; Chew, EY; Launer, L1
Holzapfel, C1
Chew, EY; Clemons, TE; Cukras, CA; Danis, RP; Domalpally, A; Friberg, TR; Sadda, SR; Toth, CA1
Bro, T; Karlsson, M1
Agrón, E; Chew, EY; Clemons, TE; Danis, RG; Domalpally, A; Ferris, FL; Keenan, TD; Klein, ML; Ratnapriya, R; Rosenfeld, PJ; Sadda, S; Swaroop, A; van Asten, F; Wong, WT1
Agrón, E; Antoszyk, AN; Chew, EY; Clemons, TE; Domalpally, A; Elman, MJ; Keenan, TD; Vitale, S1
Agrón, E; Chew, EY; Cukras, CA; Domalpally, A; Hwang, CK; Keenan, TDL; Wong, WT1
Demmelmair, H; Goeckeler-Leopold, E; Grote, V; Holdt, L; Horak, J; Koletzko, B; Maar, K; Maggini, S; Neuhofer, C; Schaefer, E; Teupser, D; Thiel, N1
Izumo, T; Kaneda, Y; Kondo, S; Nakai, M; Obata, H; Rogi, T; Saito, J; Sueyasu, T; Tokuda, H; Tsukiura, T; Yasumoto, K1

Reviews

2 review(s) available for lutein and eicosapentaenoic acid

ArticleYear
[Pharmacological therapy of age-related macular degeneration based on etiopathogenesis].
    Orvosi hetilap, 2015, Nov-15, Volume: 156, Issue:46

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Aspirin; Bosentan; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infliximab; Lutein; Macular Degeneration; Melatonin; PPAR gamma; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Resveratrol; Stilbenes; Sulfonamides; Trimetazidine; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin D; Xanthophylls

2015
[Behind blue eyes – the evidence for ocular nutritional supplements on the Swedish market].
    Lakartidningen, 2017, 08-04, Volume: 114

    Topics: Antioxidants; Blueberry Plants; Dietary Supplements; Docosahexaenoic Acids; Drug Therapy, Combination; Eicosapentaenoic Acid; Evidence-Based Medicine; Humans; Lutein; Macular Degeneration; Sweden; Vision Disorders; Vitamins; Zeaxanthins

2017

Trials

10 trial(s) available for lutein and eicosapentaenoic acid

ArticleYear
The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1).
    Ophthalmology, 2012, Volume: 119, Issue:11

    Topics: Aged; Aged, 80 and over; Dietary Supplements; Disease Progression; Docosahexaenoic Acids; Drug Therapy, Combination; Eicosapentaenoic Acid; Epidemiologic Methods; Fatty Acids, Omega-3; Female; Humans; Lutein; Macular Degeneration; Male; Middle Aged; Research Design; Treatment Outcome; Visual Acuity; Xanthophylls; Zeaxanthins

2012
Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial.
    JAMA ophthalmology, 2013, Volume: 131, Issue:5

    Topics: Aged; Aged, 80 and over; Antioxidants; Capsules; Chromans; Chromatography, High Pressure Liquid; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Gas Chromatography-Mass Spectrometry; Humans; Lipids; Lutein; Macular Degeneration; Male; Middle Aged; Retinal Pigments; Visual Acuity; Xanthophylls; Zeaxanthins

2013
Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.
    JAMA, 2013, May-15, Volume: 309, Issue:19

    Topics: Aged; beta Carotene; Dietary Supplements; Disease Progression; Docosahexaenoic Acids; Double-Blind Method; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Humans; Incidence; Lung Neoplasms; Lutein; Macular Degeneration; Male; Middle Aged; Risk; Treatment Outcome; Vitamins; Xanthophylls; Zeaxanthins; Zinc

2013
Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial.
    JAMA, 2015, Aug-25, Volume: 314, Issue:8

    Topics: Aged; Aged, 80 and over; Algorithms; Ascorbic Acid; beta Carotene; Cognition; Copper; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Hispanic or Latino; Humans; Lost to Follow-Up; Lutein; Macular Degeneration; Male; Medication Adherence; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Racial Groups; Time Factors; Vitamins; Zeaxanthins; Zinc Oxide

2015
Peripheral Retinal Changes Associated with Age-Related Macular Degeneration in the Age-Related Eye Disease Study 2: Age-Related Eye Disease Study 2 Report Number 12 by the Age-Related Eye Disease Study 2 Optos PEripheral RetinA (OPERA) Study Research Grou
    Ophthalmology, 2017, Volume: 124, Issue:4

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Fluorescein Angiography; Geographic Atrophy; Humans; Lutein; Male; Middle Aged; Optical Imaging; Prospective Studies; Retina; Retinal Drusen; Retinal Pigment Epithelium; Tomography, Optical Coherence; Wet Macular Degeneration; Zeaxanthins

2017
Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.
    Ophthalmology, 2018, Volume: 125, Issue:12

    Topics: Aged; Aged, 80 and over; Disease Progression; Docosahexaenoic Acids; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Geographic Atrophy; Humans; Lutein; Macular Degeneration; Male; Middle Aged; Photography; Prospective Studies; Visual Acuity; Zeaxanthins

2018
Visual Acuity Outcomes after Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report Number 19.
    Ophthalmology. Retina, 2020, Volume: 4, Issue:1

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Choroidal Neovascularization; Docosahexaenoic Acids; Double-Blind Method; Drug Combinations; Eicosapentaenoic Acid; Female; Follow-Up Studies; Humans; Intravitreal Injections; Lutein; Male; Middle Aged; Prospective Studies; Surveys and Questionnaires; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Wet Macular Degeneration; Zeaxanthins

2020
Progression of Geographic Atrophy with Subsequent Exudative Neovascular Disease in Age-Related Macular Degeneration: AREDS2 Report 24.
    Ophthalmology. Retina, 2021, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Diagnostic Imaging; Disease Progression; Docosahexaenoic Acids; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Follow-Up Studies; Geographic Atrophy; Humans; Lutein; Macula Lutea; Male; Middle Aged; Prospective Studies; Treatment Outcome; Wet Macular Degeneration; Zeaxanthins

2021
Multiple Micronutrients, Lutein, and Docosahexaenoic Acid Supplementation during Lactation: A Randomized Controlled Trial.
    Nutrients, 2020, Dec-16, Volume: 12, Issue:12

    Topics: Adult; beta Carotene; Breast Feeding; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Germany; Homocysteine; Humans; Infant; Lactation; Lutein; Maternal Nutritional Physiological Phenomena; Micronutrients; Milk, Human; Vitamin B 12; Vitamin D

2020
Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin on Episodic Memory in Healthy Older Adults.
    Nutrients, 2023, Jun-21, Volume: 15, Issue:13

    Topics: Aged; Arachidonic Acid; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Humans; Lutein; Memory, Episodic; Zeaxanthins

2023

Other Studies

15 other study(ies) available for lutein and eicosapentaenoic acid

ArticleYear
Dietary carotenoids and risk of colon cancer: case-control study.
    International journal of cancer, 2004, May-20, Volume: 110, Issue:1

    Topics: Adult; Aged; beta Carotene; Carotenoids; Case-Control Studies; Colonic Neoplasms; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Female; Humans; Lutein; Male; Middle Aged; Xanthophylls; Zeaxanthins

2004
Lutein and eicosapentaenoic acid interact to modify iNOS mRNA levels through the PPARgamma/RXR pathway in chickens and HD11 cell lines.
    The Journal of nutrition, 2006, Volume: 136, Issue:6

    Topics: Anilides; Animals; Cells, Cultured; Chickens; Drug Interactions; Eicosapentaenoic Acid; Female; Lutein; Macrophages; Male; Nitric Oxide Synthase Type II; PPAR gamma; Receptors, Cytoplasmic and Nuclear

2006
AMD study: a feast for the eyes.
    The Johns Hopkins medical letter health after 50, 2007, Volume: 19, Issue:10

    Topics: Aged; Aged, 80 and over; Antioxidants; beta Carotene; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Lutein; Macular Degeneration; Middle Aged; Xanthophylls; Zeaxanthins; Zinc Compounds

2007
Dietary compound score and risk of age-related macular degeneration in the age-related eye disease study.
    Ophthalmology, 2009, Volume: 116, Issue:5

    Topics: Aged; Aged, 80 and over; Ascorbic Acid; Cross-Sectional Studies; Diet; Diet Surveys; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Energy Intake; Fatty Acids, Unsaturated; Feeding Behavior; Female; Glycemic Index; Humans; Lutein; Macular Degeneration; Male; Middle Aged; Retinal Drusen; Risk Assessment; Vitamin E; Xanthophylls; Zeaxanthins; Zinc

2009
Protective actions of microalgae against endogenous and exogenous advanced glycation endproducts (AGEs) in human retinal pigment epithelial cells.
    Food & function, 2011, Volume: 2, Issue:5

    Topics: Cell Line; Cell Proliferation; Chlorella; Diabetic Retinopathy; Eicosapentaenoic Acid; Glycation End Products, Advanced; Humans; Lutein; Matrix Metalloproteinase 2; Microalgae; Plant Extracts; RNA, Messenger; Up-Regulation; Vascular Endothelial Growth Factor A; Xanthophylls

2011
Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders.
    Experimental gerontology, 2013, Volume: 48, Issue:10

    Topics: Administration, Oral; Animals; Antioxidants; Caloric Restriction; Disease Models, Animal; Eicosapentaenoic Acid; Eye Diseases; Forecasting; Humans; Lactoferrin; Lutein; Mice; Mice, Knockout; Polyphenols; Rats

2013
Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background.
    The Journal of nutrition, 2013, Volume: 143, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Chemokine CCL2; CX3C Chemokine Receptor 1; Cyclooxygenase 2; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Gene Expression Profiling; Interleukin-1beta; Lutein; Macular Degeneration; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Nitric Oxide Synthase Type II; Phenotype; Pyridinium Compounds; Receptors, Chemokine; Retina; Retinal Degeneration; Retinoids; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Xanthophylls; Zeaxanthins

2013
Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration.
    JAMA ophthalmology, 2014, Volume: 132, Issue:2

    Topics: Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Xanthophylls

2014
Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration--reply.
    JAMA ophthalmology, 2014, Volume: 132, Issue:2

    Topics: Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Xanthophylls

2014
Production of long chain omega-3 fatty acids and carotenoids in tropical areas by a new heat-tolerant microalga Tetraselmis sp. DS3.
    Food chemistry, 2016, Feb-01, Volume: 192

    Topics: Animals; beta Carotene; Biomass; Carotenoids; Chlorophyta; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Hot Temperature; Lutein; Microalgae; Tropical Climate

2016
Lifestyles and Cognitive Health: What Older Individuals Can Do to Optimize Cognitive Outcomes.
    JAMA, 2015, Aug-25, Volume: 314, Issue:8

    Topics: Cognition; Cognitive Dysfunction; Dementia; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Executive Function; Exercise Therapy; Female; Health Promotion; Humans; Lutein; Macular Degeneration; Male; Sedentary Behavior; Vitamins; Zeaxanthins

2015
Oral Nutrient Supplementation and Cognitive Function.
    JAMA, 2016, Feb-02, Volume: 315, Issue:5

    Topics: Cognition; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Vitamins; Zeaxanthins

2016
Oral Nutrient Supplementation and Cognitive Function.
    JAMA, 2016, Feb-02, Volume: 315, Issue:5

    Topics: Cognition; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Vitamins; Zeaxanthins

2016
Oral Nutrient Supplementation and Cognitive Function--Reply.
    JAMA, 2016, Feb-02, Volume: 315, Issue:5

    Topics: Cognition; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Vitamins; Zeaxanthins

2016
[Supplements for cognitive function unsuitable].
    MMW Fortschritte der Medizin, 2015, Dec-14, Volume: 157, Issue:21-22

    Topics: Cognition; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Lutein; Macular Degeneration; Male; Vitamins; Zeaxanthins

2015