luotonin-a has been researched along with pyrroloquinoline* in 1 studies
1 other study(ies) available for luotonin-a and pyrroloquinoline
Article | Year |
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One-pot synthesis of luotonin A and its analogues.
Starting with inexpensive reagents, a self-directed chemical process with the aid of a single metal triflate was readily achieved to concomitantly construct quinazoline and pyrroloquinoline cores to afford the synthesis of luotonin A and its analogues. Among all compounds prepared, 2c, 2d, and 3b exhibit more potent inhibitory activity than luotonin A against human topoisomerase I. Topics: DNA Topoisomerases, Type I; Humans; Molecular Structure; Peganum; Pyrroles; Quinazolines; Quinolines; Quinones; Topoisomerase I Inhibitors | 2011 |