luotonin-a has been researched along with 2-3-trimethylene-4-quinazolone* in 1 studies
1 other study(ies) available for luotonin-a and 2-3-trimethylene-4-quinazolone
Article | Year |
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Radical reactions with 3H-quinazolin-4-ones: synthesis of deoxyvasicinone, mackinazolinone, luotonin A, rutaecarpine and tryptanthrin.
Alkyl, aryl, heteroaryl and acyl radicals have been cyclised onto the 2-position of 3H-quinazolin-4-one. The side chains containing the radical precursors were attached to the nitrogen atom in the 3-position. The cyclisations take place by aromatic homolytic substitution hence retain the aromaticity of the 3H-quinazolin-4-one ring. The highest yields were obtained using hexamethylditin to facilitate cyclisation rather than reduction without cyclisation. The alkaloids deoxyvasicinone , mackinazolinone , tryptanthrin , luotonin A and rutaecarpine were synthesised by radical cyclisation onto 3H-quinazolin-4-one. Topics: Alkaloids; Cyclization; Free Radicals; Indole Alkaloids; Molecular Structure; Pyrroles; Quinazolines; Quinazolinones; Quinones | 2007 |