lumefantrine and tetrakis(dimethylamino)ethylene

lumefantrine has been researched along with tetrakis(dimethylamino)ethylene* in 1 studies

Other Studies

1 other study(ies) available for lumefantrine and tetrakis(dimethylamino)ethylene

ArticleYear
Original Synthesis of Fluorenyl Alcohol Derivatives by Reductive Dehalogenation Initiated by TDAE.
    Molecules (Basel, Switzerland), 2016, Oct-24, Volume: 21, Issue:10

    We report here a novel and easy-to-handle reductive dehalogenation of 9-bromofluorene in the presence of arylaldehydes and dicarbonyl derivatives to give the corresponding fluorenyl alcohol derivatives and Darzens epoxides as by-products in tetrakis(dimethylamino)ethylene (TDAE) reaction conditions. The reaction is believed to proceed via two successive single electron transfers to generate the fluorenyl anion which was able to react with different electrophiles. A mechanistic study was conducted to understand the formation of the epoxide derivatives.

    Topics: Alcohols; Anti-Inflammatory Agents, Non-Steroidal; Dimethylamines; Ethanolamines; Ethylenes; Fluorenes; Lumefantrine; Propionates

2016