Page last updated: 2024-08-21

lucanthone hydrochloride and oxamniquine

lucanthone hydrochloride has been researched along with oxamniquine in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (27.96)	18.7374
1990's	19 (20.43)	18.2507
2000's	32 (34.41)	29.6817
2010's	11 (11.83)	24.3611
2020's	5 (5.38)	2.80

Authors

Authors	Studies
Katz, N	1
Woolhouse, NM	1
Bueding, E; Haese, WH	1
Batzinger, RP; Bueding, E	1
Ong, TM	1
Kaye, B; Parke, DV; Woolhouse, NM	1
Blair, DM	1
Mello, RT; Pellegrino, J; Pereira, LH	1
Kaye, B; Woolhouse, NM	1
Bienzle, U; Dafalla, AA; de Jonge, N; Deelder, AM; Feldmeier, H; Krijger, FW; Schommer, G	1
Farag, HF; Mostafa, MH; Swelem, SM	1
Doenhoff, MJ; Fletcher, C; Sabah, AA; Webbe, G	1
Martinelli, R; Pereira, LJ; Rocha, H	1
Hassan, MM; Madwar, MA; Strickland, GT	1
Archer, S; Cioli, D; el-Hamouly, W; Pica-Mattoccia, L; Schwartz, HM	1
Archer, S; Cioli, D; Pica-Mattoccia, L	1
Cioli, D; Pica, L	1
Bruce, JI; Coles, GC; Dias, EP; Katz, N; Kinoti, GK; Mutahi, WT	1
Cioli, D; Pica-Mattoccia, L	1
Archer, S	1
el-Rooby, A	1
Andrews, BJ; Bickle, QD	1
Ancelle, T; Dupouy-Camet, J; Faurant, C; Heyer, F; Keita, A; Lapierre, J; Tourte-Schaefer, C	1
Amin, SM; Habib, YA; Hameid, LA; Hammouda, NA; Mikhail, AR	1
Bain, J; Bickle, Q; Doenhoff, M; Nelson, G; Webbe, G	1
Karekezi, CW; Lucas, PD; Marples, BA; Salt, WG	1
Awney, HA; Badawi, AF; Mostafa, MH	1
Fallon, PG; Fookes, RE; Wharton, GA	1
Ahmed, SA; Gad, MZ	1
Cook, J; Reich, MR	1
Nishioka, Sde A	1
Orduña, E; Silva, F	1
Abebe, F; Ayele, T; Birrie, H	1
Coelho, PM; Feldmann, JS; Gonçalves, R; Mello, RT; Toppa, NH	1
Butterworth, AE; Doenhoff, MJ; Fallon, PG; Fookes, RE; Mubarak, JS; Niang, M; Sturrock, RF	1
Daff, B; Gryseels, B; Niang, M; Sall, S; Sow, S; Stelma, FF	1
Cioli, D; Novi, A; Pica-Mattoccia, L	1
Butterworth, AE; Dunne, DW; Fallon, PG; Fulford, AJ; Kimani, G; Ouma, JH; Webster, M	1
Badawi, AF	1
Assis, AM; Barreto, ML; Blanton, RE; Parraga, IM; Prado, MS; Reis, MG	1
Barbosa, CS; Moza, PG; Pieri, OS	1
Coelho, PM; Lima e Silva, FC; Mello, RT; Nogueira-Machado, JA; Ribeiro, F	1
Hagan, P; Kusel, J	1
Atallah, A; Saconato, H	1
Ahmed, SM; Belal, F; El-Enany, NM; Ibrahim, F; Rizk, M	1
Ripert, C	1
Almeida, AE; Gremião, MP; Pierri, EG	1
Brandt, CT; Carvalheira, R; da Mota Braga, MV; Melo, KL; Pinho Sá, H	1
Barbosa, CS; Beck, L; Domas, GG; Favre, TC; Pieri, OS; Zani, LC	1
Baz, ME; El-Agroudy, AE; Ghoneim, MA; Mahmoud, KM; Mostafa, FE; Shokeir, AA; Sobh, MA	1
Alves, JG; Ulisses Montenegro, FM	1
Chiodelli, SG; da Silva, RM; da Silveira, MA; Filho, SB; Gargioni, C; Gurgel Vellosa, SA; Silva Pinto, PL	1
Bonesso-Sabadini, PI; de Souza Dias, LC	1
Casella, EB; Marques-Dias, MJ; Paz, JA; Valente, M	1
Barbosa, CS; Beck, LH; Domas, GG; Favre, TC; Ferreira, JM; Pieri, OS; Zani, LC	1
Borges-Pereira, J; Conceicao, MJ	1
Livramento, JA; Marques-Dias, MJ; Nobrega, JP; Peregrino, AJ; Puglia, PM; Scaff, M	1
Mbugua, GG; Ouma, JH; Sturrock, RK; Thiong'o, FW	1
Abath, FG; Gomes, YM; Montarroyos, U; Nakazawa, M; Pereira, VR; Souza, WV	1
de Carvalho, ME; de Lima, VR; Fadel, ML; Santos Ferreira, C; Teles, HM; Zacharias, F	1
Antunes, CM; Coelho, PM; da Cunha, AS; Ferrari, ML; Tavares, CA	1
Leite, KR; Lopes, RI; Lopes, RN; Prando, D	2
Engels, D; Fenwick, A; Robert Bergquist, N; Savioli, L; Todd, MH	1
Amorim, A; Enk, MJ; Schall, VT	1
Aguiar, BG; Coelho, PM; Costa, G; Cunha-Melo, JR	1
Bicalho, RS; Carvalho, MG; Coelho, PM; Lima e Silva, FC; Mello, RT; Soares, AL	1
Antunes, CM; Cota, GF; Lambertucci, JR; Pinto-Silva, RA	1
Aular, S; García, N; Incani, RN; Isturiz, G	1
Brandt, CA; da Silveira, MA; de Souza Menezes, CM; Filho, RP; Paula, GA; Pinto, PL	1
Carlini, D; Cimica, V; Cioli, D; Guidi, A; Pica-Mattoccia, L; Vigorosi, F	1
Abath, FG; Aroucha, ML; Barbosa, CS; Carvalho Júnior, LB; de Souza, JR; Domingues, AL; Miranda, PJ; Montenegro, SM; Morais, CN	1
Enk, MJ; Katz, N; Zech Coelho, PM	1
Araújo, N; Coelho, PM; Katz, N; Mattos, AC; Sarvel, AK	1
Araujo, N; Coelho, PM; Katz, N; Mattos, AC	1
Flescher, E; Gold, D; Goldberg, M; Lengy, J	1
Conceição, MJ; Coura, JR	1
Danso-Appiah, A; Donegan, S; Olliaro, PL; Sinclair, D; Utzinger, J	1
Aguilar, H; Almeida, M; Anderson, TJ; Basso, A; Berriman, M; Cao, X; Carvalho-Queiroz, C; Chevalier, FD; Cioli, D; Frantz, DE; Guidi, A; Hart, PJ; Holloway, SP; LoVerde, PT; Pica-Mattoccia, L; Taylor, AB; Tsai, IJ; Valentim, CL	1
Araújo, N; Coelho, PM; Katz, N; Kusel, JR; Vimieiro, AC	1
Anderson, TJ; Chevalier, FD; LoVerde, PT; Valentim, CL	1
Nunes, MB; Petroianu, A; Sabino, KR	1
Anderson, TJ; Assis, RR; Cao, X; Chevalier, FD; Eng, N; Hart, PJ; Holloway, SP; Le Clec'h, W; LoVerde, PT; Oliveira, G; Rugel, AR	1
Atella, GC; Augusto, RC; Cabral, SS; Coelho, PMZ; de Souza, S; Faro, MJ; Gabriel Kluck, GE; Lima, RN; Mattos, ACA; Mello Silva, CC; Mota, EM	1
Buchter, V; Gasser, G; Hess, J; Keiser, J	1
Anisuzzaman, A; Frahm, S; Prazeres da Costa, C; Prodjinotho, UF; Vejzagić, N; Verschoor, A	1
Ezebuo, FC; Uzochukwu, IC	1
Al Mashikhi, KM; Al Yafae, S; Anderson, TJC; Cao, X; Chevalier, FD; Emery, AM; Garba Djirmay, A; Gouvras, AN; Guzman, MA; Hart, PJ; Holloway, SP; Idris, MA; Kinung'hi, S; Le Clec'h, W; LoVerde, PT; McDew-White, M; Menon, V; Moné, H; Mouahid, G; Rollinson, D; Taylor, AB; Webster, BL; Webster, JP	1
Cao, X; Guzman, M; LoVerde, PT; McHardy, SF; Rugel, A; Tarpley, RS; Taylor, AB	1
Anderson, TJC; Cao, X; Chevalier, FD; Guzman, MA; Hart, PJ; Holloway, SP; LoVerde, PT; McHardy, SF; Rugel, AR; Tarpley, RS; Taylor, AB	1
Gallinger, TL; Grevelding, CG; Grünweller, A; Haeberlein, S; Lange-Grünweller, K; Mäder, P; Rennar, GA; Schlitzer, M	1
Alwan, S; Cameron, MD; Khan, S; LoVerde, PT; McHardy, SF; Toth, K	1

Reviews

9 review(s) available for lucanthone hydrochloride and oxamniquine

Article	Year
Chemotherapy of Schistosomiasis mansoni. Advances in pharmacology and chemotherapy, 1977, Volume: 14 Topics: Amphotericin B; Animals; Antimony; Chemosterilants; Drug Evaluation; Drug Evaluation, Preclinical; Eggs; Emetine; Humans; Hycanthone; Lucanthone; Naphthalenes; Niridazole; Nitrofurans; Organophosphorus Compounds; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Snails; Thiazoles; Thiophenes; Tubercidin	1977
Biochemical and pharmacological effects in relation to the mode of action of antischistosomal drugs. Biochemical pharmacology, 1979, Aug-15, Volume: 28, Issue:16 Topics: Animals; Antimony; Carbohydrate Metabolism; Glycogen; Heterocyclic Compounds; Hycanthone; Neurotransmitter Agents; Niridazole; Oxamniquine; Schistosoma; Schistosomicides	1979
Genetic activities of hycanthone and some other antischistosomal drugs. Mutation research, 1978, Volume: 55, Issue:1 Topics: Acrylamides; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophila; Genes, Dominant; Genes, Lethal; Humans; Hycanthone; Lucanthone; Mice; Mutagens; Mutation; Niridazole; Nitrofurans; Oxamniquine; Rabbits; Rats; Saccharomyces cerevisiae; Salmonella typhimurium; Schistosomicides; Species Specificity; Teratogens; Thioxanthenes; Trichlorfon	1978
The chemotherapy of schistosomiasis. Annual review of pharmacology and toxicology, 1985, Volume: 25 Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazole; Oxamniquine; Praziquantel; Pyrazines; Schistosomiasis; Schistosomicides; Thiocyanates; Thiones; Thiophenes; Trichlorfon	1985
Management of hepatic schistosomiasis. Seminars in liver disease, 1985, Volume: 5, Issue:3 Topics: Acute Disease; Animals; Central Nervous System; Child; Chronic Disease; Colon; Diagnosis, Differential; Hepatitis, Viral, Human; Humans; Hypertension, Portal; Kidney; Liver; Liver Diseases, Parasitic; Mice; Niridazole; Oxamniquine; Praziquantel; Radiography; Salmonella Infections; Schistosomiasis; Schistosomicides; Sclerosing Solutions	1985
Interventions for treating schistosomiasis mansoni. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides	2000
Spinal cord schistosomiasis in children: analysis of seven cases. Arquivos de neuro-psiquiatria, 2002, Volume: 60, Issue:2-A Topics: Adolescent; Anthelmintics; Anti-Inflammatory Agents; Child; Child, Preschool; Female; Humans; Magnetic Resonance Imaging; Male; Oxamniquine; Praziquantel; Prednisone; Schistosomiasis mansoni; Schistosomicides; Spinal Cord Diseases	2002
Drugs for the control of parasitic diseases: current status and development in schistosomiasis. Trends in parasitology, 2003, Volume: 19, Issue:11 Topics: Animals; Drug Resistance; Humans; Oxamniquine; Praziquantel; Public Health; Schistosoma; Schistosomiasis; Schistosomicides; Treatment Outcome	2003
Drugs for treating Schistosoma mansoni infection. The Cochrane database of systematic reviews, 2013, Feb-28, Issue:2 Topics: Adolescent; Adult; Child; Commiphora; Humans; Oxamniquine; Plant Extracts; Praziquantel; Randomized Controlled Trials as Topic; Resins, Plant; Schistosomiasis mansoni; Schistosomicides	2013

Trials

5 trial(s) available for lucanthone hydrochloride and oxamniquine

Article	Year
Mixed Schistosoma haematobium and S. mansoni infection: effect of different treatments on the serum level of circulating anodic antigen (CAA). Acta tropica, 1990, Volume: 48, Issue:1 Topics: Animals; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Humans; Male; Oxamniquine; Parasite Egg Count; Praziquantel; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis haematobia; Schistosomiasis mansoni; Schistosomicides; Trichlorfon; Urine	1990
Oxamniquine cures Schistosoma mansoni infection in a focus in which cure rates with praziquantel are unusually low. The Journal of infectious diseases, 1997, Volume: 176, Issue:1 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides	1997
Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil. The American journal of clinical nutrition, 1998, Volume: 68, Issue:6 Topics: Adolescent; Anthropometry; Body Mass Index; Body Weight; Brazil; Child; Double-Blind Method; Female; Humans; Male; Nutritional Status; Oxamniquine; Placebos; Schistosomiasis mansoni; Schistosomicides; Skinfold Thickness	1998
Schistosomiasis control based on repeated chemotherapy in a rural village of the sugar-cane zone in northeast Brazil. Memorias do Instituto Oswaldo Cruz, 1998, Volume: 93 Suppl 1 Topics: Adolescent; Brazil; Child, Preschool; Drug Administration Schedule; Endemic Diseases; Health Surveys; Humans; Oxamniquine; Prevalence; Rural Health; Schistosomiasis; Schistosomicides; Time Factors	1998
Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial. Bulletin of the World Health Organization, 2003, Volume: 81, Issue:3 Topics: Adult; Animals; Brazil; Feces; Female; Humans; Male; Oxamniquine; Parasite Egg Count; Placebos; Praziquantel; Prospective Studies; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Sensitivity and Specificity; Treatment Outcome	2003

Other Studies

79 other study(ies) available for lucanthone hydrochloride and oxamniquine

Article	Year
Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3 Topics: Animals; Carcinoma, Hepatocellular; Female; Hycanthone; Indazoles; Liver; Liver Neoplasms; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thioxanthenes	1976
Mutagenic activities in vitro and in vivo of five antischistosomal compounds. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1 Topics: Animals; Female; Hycanthone; Mice; Microsomes, Liver; Mutagens; Oxamniquine; Salmonella typhimurium; Schistosoma mansoni; Schistosomicides; Trichlorfon	1977
Sepcies differences in N-dealkylation of oxamniquine. Xenobiotica; the fate of foreign compounds in biological systems, 1979, Volume: 9, Issue:5 Topics: Animals; Bile; Chlorocebus aethiops; Dealkylation; In Vitro Techniques; Liver; Male; Mice; Nitroquinolines; Oxamniquine; Rabbits; Rats; Schistosomicides; Species Specificity; Subcellular Fractions	1979
Treatment of bilharziasis due to Schistosoma haematobium infection. The Central African journal of medicine, 1977, Volume: 23, Issue:11 Suppl Topics: Administration, Oral; Humans; Oxamniquine; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Trichlorfon	1977
Activity of known antischistosomal agents on early-developing forms of Schistosoma mansoni. The Journal of parasitology, 1975, Volume: 61, Issue:2 Topics: Animals; Antimony; Diethylamines; Edetic Acid; Hycanthone; Lithium; Lucanthone; Mice; Oxamniquine; Schistosomiasis; Schistosomicides; Thiomalates; Toluidines; Trichlorfon	1975
The metabolism of oxamniquine - a new schistosomicide. Annals of tropical medicine and parasitology, 1976, Volume: 70, Issue:3 Topics: Animals; Cricetinae; Dogs; Female; Haplorhini; Humans; Macaca mulatta; Male; Mice; Nitroquinolines; Oxamniquine; Rabbits; Rats; Schistosomicides	1976
Modification of cytochrome P-450, NADPH-cytochrome c reductase and aryl hydrocarbon hydroxylase activities by schistosomicidal drugs. Biochemical pharmacology, 1989, Jan-15, Volume: 38, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Niridazole; Oxamniquine; Schistosomicides	1989
Schistosoma mansoni: chemotherapy of infections of different ages. Experimental parasitology, 1986, Volume: 61, Issue:3 Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thiocyanates; Time Factors	1986
The influence of anti-parasitic therapy on the course of the glomerulopathy associated with Schistosomiasis mansoni. Clinical nephrology, 1987, Volume: 27, Issue:5 Topics: Humans; Hycanthone; Kidney; Kidney Diseases; Oxamniquine; Schistosomiasis mansoni; Schistosomicides	1987
Circulating antigens for assessing cure in schistosomiasis mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:6 Topics: Adolescent; Adult; Antibodies, Helminth; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Female; Humans; Male; Oxamniquine; Parasite Egg Count; Praziquantel; Pyrazines; Schistosomiasis mansoni; Schistosomicides; Thiones; Thiophenes	1988
Studies on some derivatives of oxamniquine. Journal of medicinal chemistry, 1988, Volume: 31, Issue:8 Topics: Animals; Chemical Phenomena; Chemistry; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship; Tritium; Uridine	1988
Schistosomicides and DNA functioning. Biochemical Society transactions, 1987, Volume: 15, Issue:1 Topics: Animals; DNA; Female; Hycanthone; Male; Oxamniquine; Schistosoma; Schistosomicides; Structure-Activity Relationship	1987
[Genetic and molecular aspects of drug resistance in Schistosoma mansoni]. Annali dell'Istituto superiore di sanita, 1986, Volume: 22, Issue:1 Topics: Animals; Carbamates; Drug Resistance; HeLa Cells; Humans; Hycanthone; Oxamniquine; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship	1986
The chemotherapy of schistosomiasis control. Bulletin of the Pan American Health Organization, 1986, Volume: 20, Issue:1 Topics: Child; Humans; Oxamniquine; Praziquantel; Schistosomiasis; Schistosomicides; Trichlorfon	1986
Drug resistance in schistosomiasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:2 Topics: Animals; Drug Resistance; Mice; Oxamniquine; Praziquantel; Pyrazines; Schistosoma mansoni; Schistosomicides; Thiones; Thiophenes	1986
Studies on the mode of action of oxamniquine and related schistosomicidal drugs. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:1 Topics: Animals; Chemical Phenomena; Chemistry; Female; Hycanthone; Lucanthone; Male; Mice; Nitroquinolines; Oxamniquine; Rats; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides	1985
Resistance following drug attenuation (Ro 11-3128 or oxamniquine) of early Schistosoma mansoni infections in mice. Parasitology, 1985, Volume: 90 ( Pt 2) Topics: Animals; Benzodiazepinones; Female; Mice; Mice, Inbred CBA; Nitroquinolines; Oxamniquine; Schistosoma japonicum; Schistosomiasis; Schistosomicides	1985
[Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1983, Volume: 76, Issue:5 Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Isoquinolines; Middle Aged; Nitroquinolines; Oxamniquine; Paris; Praziquantel; Pyrazines; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes; Togo	1983
Effect of some new antibilharzial drugs on oxygen consumption of mouse diaphragm and liver homogenates in experimental bilharziasis. Journal of the Egyptian Society of Parasitology, 1982, Volume: 12, Issue:1 Topics: Animals; Diaphragm; Liver; Male; Mice; Oxamniquine; Oxygen Consumption; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Triazoles	1982
Factors affecting the acquisition of resistance against Schistosoma mansoni in the mouse. V. Reduction in the degree of resistance to reinfection after chemotherapeutic elimination of recently patent primary infections. Journal of helminthology, 1980, Volume: 54, Issue:1 Topics: Animals; Antimony Potassium Tartrate; Hycanthone; Immunity, Active; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomicides	1980
Preliminary investigations of some derivatives of oxamniquine. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:2 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Oxamniquine; Schistosomicides; Seizures	1995
Formation of promutagenic methylation damage in tissue-DNA of mice treated with antischistosomal agents. Cancer letters, 1993, Dec-20, Volume: 75, Issue:3 Topics: Alkylation; Animals; Deoxyguanosine; DNA; DNA Damage; Hycanthone; Kidney; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Oxamniquine; Schistosomicides; Spleen; Trichlorfon; Urinary Bladder	1993
Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy. Parasitology, 1996, Volume: 112 ( Pt 1) Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Female; Immunization, Passive; Male; Mice; Mice, Inbred CBA; Microscopy, Electron, Scanning; Oxamniquine; Praziquantel; Rabbits; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Snails	1996
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers. Arzneimittel-Forschung, 1995, Volume: 45, Issue:12 Topics: Animals; Body Weight; Citric Acid Cycle; Female; Glucose; Glycolysis; Liver; Liver Glycogen; Male; Mice; Organ Size; Oxamniquine; Pentose Phosphate Pathway; Praziquantel; Pyrazines; Schistosomiasis mansoni; Schistosomicides; Thiones; Thiophenes	1995
Case 4-1996: paralysis due to schistosomiasis. The New England journal of medicine, 1996, Jun-06, Volume: 334, Issue:23 Topics: Drug Resistance; Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides	1996
Case 4-1996: paralysis due to schistosomiasis. The New England journal of medicine, 1996, Jun-06, Volume: 334, Issue:23 Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides; Spinal Cord Diseases	1996
Scintigraphic findings in schistosomiasis. Puerto Rico health sciences journal, 1995, Volume: 14, Issue:4 Topics: Acute Disease; Adolescent; Child; Follow-Up Studies; Hepatomegaly; Humans; Liver Function Tests; Male; Oxamniquine; Radionuclide Imaging; Schistosomiasis mansoni; Schistosomicides; Splenomegaly; Treatment Outcome	1995
The efficacy of oxamniquine in selective population chemotherapy in Ethiopia. Ethiopian medical journal, 1995, Volume: 33, Issue:4 Topics: Adolescent; Adult; Child; Child, Preschool; Ethiopia; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Oxamniquine; Parasite Egg Count; Patient Compliance; Pilot Projects; Schistosomiasis mansoni; Schistosomicides; Treatment Outcome	1995
Schistosoma mansoni: permanence of modulation of the granulomatous inflammatory response in mice cured in the chronic phase. International journal for parasitology, 1996, Volume: 26, Issue:12 Topics: Animals; Granuloma; Inflammation; Liver Diseases, Parasitic; Mice; Oxamniquine; Schistosomiasis mansoni; Schistosomicides	1996
Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates. Experimental parasitology, 1997, Volume: 86, Issue:1 Topics: Animals; Digestive System; Drug Resistance; Feces; Female; Fertility; Kenya; Liver; Male; Mice; Oxamniquine; Parasite Egg Count; Praziquantel; Puerto Rico; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Senegal; Sex Ratio	1997
Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections. Parasitology research, 1997, Volume: 83, Issue:7 Topics: Animals; Biotransformation; Hycanthone; Macromolecular Substances; Male; Oxamniquine; Schistosoma haematobium; Schistosoma mansoni; Schistosomicides; Species Specificity	1997
Effect of praziquantel and oxamniquine treatment on human isotype responses to Schistosoma mansoni: elevated IgE to adult worm. Parasite immunology, 1997, Volume: 19, Issue:7 Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Drug Therapy, Combination; Female; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Ovum; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	1997
O6-methylguanine and O6-methylguanine-DNA [corrected] methyltransferase activity in tissues of BDF-1 mice treated with antiparasitic drugs. Toxicology letters, 1998, Volume: 94, Issue:3 Topics: Animals; DNA Damage; Guanine; Hycanthone; Intestines; Liver; Male; Mice; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Oxamniquine; Schistosomicides; Trichlorfon; Urinary Bladder	1998
Activity of oxamniquine at skin, pulmonary and sexual maturation phases, on a Schistosoma mansoni strain (R1) previously reported as resistant at the adult phase. Memorias do Instituto Oswaldo Cruz, 1998, Volume: 93 Suppl 1 Topics: Animals; Drug Resistance; Female; Life Cycle Stages; Male; Mice; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	1998
Praziquantel--its use, cost and possible development of resistance. Parasitology today (Personal ed.), 1999, Volume: 15, Issue:9 Topics: Africa; Animals; Anthelmintics; Child; Drug Resistance; Female; Humans; Oxamniquine; Praziquantel; Pregnancy; Quality Control; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Trichlorfon	1999
A simple kinetic spectrophotometric method for the determination of oxamniquine in formulations and spiked biological fluids. Journal of pharmaceutical and biomedical analysis, 2000, Aug-15, Volume: 23, Issue:2-3 Topics: Body Fluids; Calibration; Humans; Kinetics; Oxamniquine; Pharmaceutical Preparations; Schistosomicides; Spectrophotometry, Ultraviolet	2000
[Schistosomiasis: diagnosis and treatment]. Presse medicale (Paris, France : 1983), 2000, Sep-30, Volume: 29, Issue:28 Topics: Animals; Anthelmintics; Humans; Oxamniquine; Praziquantel; Prognosis; Schistosomiasis; Schistosomicides	2000
Determination of oxamniquine in capsules by HPLC. Journal of pharmaceutical and biomedical analysis, 2001, Volume: 26, Issue:4 Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Oxamniquine; Schistosomicides	2001
Surgical hepatosplenic mansonic schistosomiasis in adolescents: repercussions of the post-treatment schistosomotic burden on the hepatic functional reserve. Memorias do Instituto Oswaldo Cruz, 2001, Volume: 96 Suppl Topics: Adolescent; Animals; Child; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Liver; Liver Diseases, Parasitic; Oxamniquine; Rectum; Recurrence; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Splenic Diseases	2001
Replacing oxamniquine by praziquantel against Schistosoma mansoni infection in a rural community from the sugar-cane zone of Northeast Brazil: an epidemiological follow-up. Memorias do Instituto Oswaldo Cruz, 2001, Volume: 96 Suppl Topics: Animals; Anthelmintics; Brazil; Crops, Agricultural; Follow-Up Studies; Humans; Oxamniquine; Parasite Egg Count; Praziquantel; Prevalence; Prognosis; Recurrence; Rural Health; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Seasons	2001
Impact of schistosomiasis on patient and graft outcome after renal transplantation: 10 years' follow-up. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:11 Topics: Adult; Anthelmintics; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Oxamniquine; Praziquantel; Risk Factors; Schistosomiasis; Schistosomicides; Treatment Outcome; Urinary Tract Infections	2001
Portal hypertension due to schistosomiasis. Indian pediatrics, 2001, Volume: 38, Issue:12 Topics: Child, Preschool; Female; Humans; Hypertension, Portal; Liver Diseases, Parasitic; Oxamniquine; Schistosomiasis; Schistosomicides	2001
Synthesis and evaluation of new oxamniquine derivatives. International journal of pharmaceutics, 2002, Feb-21, Volume: 233, Issue:1-2 Topics: Animals; Drug Evaluation, Preclinical; Male; Mice; Oxamniquine; Schistosomiasis mansoni; Schistosomicides; Structure-Activity Relationship	2002
Altered response of strain of Schistosoma mansoni to oxamniquine and praziquantel. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97, Issue:3 Topics: Animals; Drug Resistance; Female; Humans; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2002
Longitudinal Study on the Natural Infection of Biomphalaria straminea and B. glabrata by Schistosoma mansoni in an Endemic Area of Schistosomiasis in Pernambuco, Brazil. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97, Issue:4 Topics: Animals; Biomphalaria; Brazil; Disease Vectors; Longitudinal Studies; Oxamniquine; Population Density; Schistosoma mansoni; Schistosomicides; Seasons	2002
Influence of specific treatment on the morbidity of Schistosomiasis mansoni in an endemic area of Minas Gerais, Brazil. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97, Issue:5 Topics: Animals; Brazil; Endemic Diseases; Follow-Up Studies; Humans; Oxamniquine; Prevalence; Schistosomiasis mansoni; Schistosomicides	2002
[Schistosomiasis of the spinal cord: analysis of 80 cases]. Arquivos de neuro-psiquiatria, 2002, Volume: 60, Issue:3-A Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Brazil; Child; Child, Preschool; Dexamethasone; Female; Humans; Male; Middle Aged; Oxamniquine; Praziquantel; Prednisone; Prospective Studies; Schistosomiasis mansoni; Schistosomicides; Spinal Cord Diseases	2002
Efficacy of oxamniquine and praziquantel in school children from two Schistosoma mansoni endemic areas. East African medical journal, 2002, Volume: 79, Issue:1 Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Endemic Diseases; Humans; Logistic Models; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Schools; Treatment Outcome	2002
Antibody isotype responses to egg antigens in human chronic Schistosomiasis mansoni before and after treatment. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97 Suppl 1 Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Brazil; Enzyme-Linked Immunosorbent Assay; Feces; Humans; Immunoglobulin E; Immunoglobulin G; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2002
Schistosomiasis mansoni in Bananal (State of São Paulo, Brazil): I. Efficiency of diagnostic and treatment procedures. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97 Suppl 1 Topics: Adolescent; Adult; Animals; Brazil; Child; Child, Preschool; Feces; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Oxamniquine; Parasite Egg Count; Prevalence; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Urban Population	2002
Testicular schistosomiasis simulating malignancy. The Lancet. Infectious diseases, 2003, Volume: 3, Issue:9 Topics: Adult; Humans; Male; Oxamniquine; Schistosomiasis mansoni; Schistosomicides; Testicular Diseases	2003
Acute schistosomiasis outbreak in the metropolitan area of Belo Horizonte, Minas Gerais: alert about the risk of unnoticed transmission increased by growing rural tourism. Memorias do Instituto Oswaldo Cruz, 2003, Volume: 98, Issue:6 Topics: Acute Disease; Animals; Biomphalaria; Brazil; Disease Outbreaks; Feces; Female; Health Knowledge, Attitudes, Practice; Humans; Male; Oxamniquine; Parasite Egg Count; Praziquantel; Risk Factors; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Swimming Pools; Travel; Urban Population	2003
On the increase of portal pressure during the acute and chronic phases of murine schistosomiasis mansoni and its reversibility after treatment with oxamniquine. Acta tropica, 2003, Volume: 89, Issue:1 Topics: Animals; Hypertension, Portal; Male; Mice; Oxamniquine; Schistosomiasis mansoni; Schistosomicides	2003
Murine schistosomiasis mansoni: process of blood coagulation at pre-patent, acute and chronic phases, and consequence of chemotherapeutic cure on the reversion of changes. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:7 Topics: Acute Disease; Animals; Blood Coagulation; Blood Coagulation Factors; Chronic Disease; Female; Mice; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2005
Ultrasound and clinical investigation of hepatosplenic schistosomiasis: evaluation of splenomegaly and liver fibrosis four years after mass chemotherapy with oxamniquine. The American journal of tropical medicine and hygiene, 2006, Volume: 74, Issue:1 Topics: Adolescent; Adult; Alcoholism; Female; Humans; Liver Cirrhosis; Logistic Models; Male; Multivariate Analysis; Oxamniquine; Schistosomiasis; Schistosomicides; Splenomegaly; Ultrasonography	2006
The efficacy of human schistosomicide treatment may depend on the rate of transmission. Parasitology research, 2006, Volume: 98, Issue:6 Topics: Animals; Antibodies, Helminth; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin M; Oxamniquine; Praziquantel; Precipitin Tests; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Treatment Outcome; Venezuela	2006
Design, synthesis, and in vivo evaluation of oxamniquine methacrylate and acrylamide prodrugs. Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3 Topics: Acrylamide; Animals; Drug Design; Drug Evaluation, Preclinical; Male; Mesenteric Veins; Methacrylates; Mice; Models, Molecular; Oxamniquine; Prodrugs; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Structure-Activity Relationship	2007
The schistosome enzyme that activates oxamniquine has the characteristics of a sulfotransferase. Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101 Suppl 1 Topics: Animals; Drug Resistance; Enzyme Activation; Oxamniquine; Schistosoma; Schistosomicides; Sulfotransferases	2006
Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens. Memorias do Instituto Oswaldo Cruz, 2007, Volume: 102, Issue:2 Topics: Acute Disease; Adolescent; Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Child; Disease Outbreaks; Enzyme-Linked Immunosorbent Assay; Feces; Female; Humans; Immunoglobulin E; Interferon-gamma; Male; Oxamniquine; Parasite Egg Count; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2007
Testicular schistosomiasis caused by Schistosoma mansoni: a case report from Brazil. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2007, Volume: 11, Issue:5 Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Orchiectomy; Oxamniquine; Schistosomiasis mansoni; Schistosomicides; Testicular Diseases	2007
A case of Schistosoma mansoni infection treated during the prepatent period. Nature clinical practice. Gastroenterology & hepatology, 2008, Volume: 5, Issue:2 Topics: Administration, Oral; Adult; Animals; Dose-Response Relationship, Drug; Feces; Female; Follow-Up Studies; Humans; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2008
Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. Memorias do Instituto Oswaldo Cruz, 2008, Volume: 103, Issue:5 Topics: Animals; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2008
Association of oxamniquine praziquantel and clonazepam in experimental Schistosomiasis mansoni. Memorias do Instituto Oswaldo Cruz, 2008, Volume: 103, Issue:8 Topics: Animals; Clonazepam; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Liver; Male; Mesentery; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Time Factors	2008
Effect of oxamniquine on Schistosoma mansoni: some biological and biochemical observations. Biochemical pharmacology, 1980, Mar-01, Volume: 29, Issue:5 Topics: Animals; Dose-Response Relationship, Drug; Female; Host-Parasite Interactions; Male; Mice; Mice, Inbred ICR; Ornithine-Oxo-Acid Transaminase; Oxamniquine; Parasitic Sensitivity Tests; Schistosoma mansoni; Schistosomicides; Time Factors	1980
Specific schistosomiasis treatment as a strategy for disease control. Memorias do Instituto Oswaldo Cruz, 2010, Volume: 105, Issue:4 Topics: Brazil; Cohort Studies; Female; Humans; Oxamniquine; Parasite Egg Count; Pregnancy; Prevalence; Schistosomiasis mansoni; Schistosomicides	2010
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites. Science (New York, N.Y.), 2013, Dec-13, Volume: 342, Issue:6164 Topics: Amino Acid Sequence; Animals; Drug Resistance; Gene Knockdown Techniques; Genetic Linkage; Helminth Proteins; Humans; Molecular Sequence Data; Mutation; Oxamniquine; Phylogeny; Protein Conformation; Quantitative Trait Loci; RNA Interference; Schistosoma mansoni; Schistosomicides; Sulfotransferases	2013
Schistogram changes after administration of antischistosomal drugs in mice at the early phase of Schistosoma mansoni infection. Memorias do Instituto Oswaldo Cruz, 2013, Volume: 108, Issue:7 Topics: Animals; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Mice; Oxamniquine; Parasite Egg Count; Parasitemia; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2013
Efficient linkage mapping using exome capture and extreme QTL in schistosome parasites. BMC genomics, 2014, Jul-21, Volume: 15 Topics: Animals; Chromosome Mapping; Cricetinae; Crosses, Genetic; Exome; Female; Gene Frequency; Genetic Linkage; Genotype; Male; Oxamniquine; Phenotype; Quantitative Trait Loci; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Sulfotransferases	2014
Ectopic Schistosoma mansoni Eggs Inside a Lipoma. The American journal of tropical medicine and hygiene, 2016, Volume: 94, Issue:1 Topics: Adult; Animals; Humans; Lipoma; Male; Ovum; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2016
Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population. International journal for parasitology, 2016, Volume: 46, Issue:7 Topics: Alleles; Animals; Brazil; Child; Child, Preschool; Drug Resistance; Exons; Feces; Gene Frequency; Genome-Wide Association Study; Humans; Infant; Molecular Conformation; Mutation; Oxamniquine; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Schistosoma mansoni; Schistosomiasis; Schistosomicides	2016
Combined treatment of Biomphalaria glabrata infected by Schistosoma mansoni with oxamniquine and praziquantel: Reproductive histological and metabolic aspects. Experimental parasitology, 2017, Volume: 183 Topics: Animals; Anthelmintics; Biomphalaria; Cholesterol; Feces; Fertility; Hemolymph; Humans; Lipid Metabolism; Mice; Oviposition; Oxamniquine; Praziquantel; Reproduction; Schistosomicides	2017
Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine using scanning electron microscopy. Parasites & vectors, 2018, Nov-06, Volume: 11, Issue:1 Topics: Animals; Female; Inhibitory Concentration 50; Mice; Microscopy, Electron, Scanning; Organometallic Compounds; Oxamniquine; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides	2018
A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing. PLoS neglected tropical diseases, 2019, Volume: 13, Issue:1 Topics: Animals; Artemether; Cercaria; Culture Media, Serum-Free; Drug Evaluation, Preclinical; Humans; Mefloquine; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2019
Schistosomal Sulfotransferase Interaction with Oxamniquine Involves Hybrid Mechanism of Induced-fit and Conformational Selection. Current computer-aided drug design, 2020, Volume: 16, Issue:4 Topics: Animals; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Oxamniquine; Prodrugs; Schistosoma; Schistosomiasis; Schistosomicides; Sulfotransferases	2020
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment. PLoS pathogens, 2019, Volume: 15, Issue:10 Topics: Adaptation, Physiological; Alleles; Animals; Cricetinae; Drug Resistance; Humans; Niger; Oman; Oxamniquine; Polymorphism, Single Nucleotide; Rats; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Senegal; Snails; Tanzania	2019
Molecular basis for hycanthone drug action in schistosome parasites. Molecular and biochemical parasitology, 2020, Volume: 236 Topics: Animals; Crystallization; Crystallography, X-Ray; Drug Design; Drug Resistance; Humans; Hycanthone; Oxamniquine; Praziquantel; Protein Binding; Recombinant Proteins; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sulfotransferases	2020
Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum? International journal for parasitology. Drugs and drug resistance, 2020, Volume: 13 Topics: Animals; Molecular Structure; Oxamniquine; Schistosoma; Schistosoma haematobium; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides; Sulfotransferases	2020
Disulfiram and dithiocarbamate analogues demonstrate promising antischistosomal effects. European journal of medicinal chemistry, 2022, Nov-15, Volume: 242 Topics: Adult; Aldehyde Dehydrogenase; Animals; Disulfiram; Humans; Neglected Diseases; Nitrogen; Oxamniquine; Piperazines; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sulfur	2022
Addressing the oxamniquine in vitro-in vivo paradox to facilitate a new generation of anti-schistosome treatments. International journal for parasitology. Drugs and drug resistance, 2023, Volume: 21 Topics: Animals; Humans; Mice; Oxamniquine; Schistosoma; Schistosoma mansoni; Schistosomicides	2023