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lucanthone hydrochloride and hycanthone

lucanthone hydrochloride has been researched along with hycanthone in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199034 (82.93)18.7374
1990's5 (12.20)18.2507
2000's1 (2.44)29.6817
2010's0 (0.00)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Katz, N1
Coulaud, JP; Payet, M1
Woolhouse, NM1
Yokogawa, M1
de Serres, FJ; Ong, T1
Bueding, E; Haese, WH1
Batzinger, RP; Bueding, E1
Ong, TM1
Ascher, G; Hildebrandt, J; Mieth, H; Reinshagen, H1
El-Kabbaj, M; Hassar, M1
Mello, RT; Pellegrino, J; Pereira, LH1
Hartman, PE; Hulbert, PB1
Hillman, GR; Senft, AW1
Davis, A1
Bueding, E1
Adler, ID; Kliesch, U1
Doenhoff, MJ; Fletcher, C; Sabah, AA; Webbe, G1
Martinelli, R; Pereira, LJ; Rocha, H1
Brindley, PJ; Sher, A1
Archer, S; Cioli, D; Pica-Mattoccia, L; Seyed-Mozaffari, A; Zayed, AH1
Chiang, PK; Gordon, RK1
Archer, S; Cioli, D; Pica-Mattoccia, L1
Cioli, D; Pica, L1
Cioli, D; Pica-Mattoccia, L1
Archer, S1
Archer, S; Cioli, D; Pica-Mattoccia, L; Rosenberg, S1
Berberian, DA; Davison, C; Dennis, EW; Donikian, MA; Drobeck, HP; Farah, A; Ferrari, RA; Yarinsky, A1
El-Abdin, AZ; El-Garem, AA; El-Raziky, EH; Fadl, AA; Mousa, AH1
Abd-El-Rahman, H; Adham, IA; El-Abdin, AZ; El-Raziky, EH; Hafez, S; Mousa, AH; Roshdy, MZ; Samy, G1
Dennis, EW; Kobus, W1
Manshande, JP; Polderman, AM1
Clarkson, J; Erasmus, DA1
el Sadany, SK; Mokhtar, HM; Soliman, R1
Bain, J; Bickle, Q; Doenhoff, M; Nelson, G; Webbe, G1
Erasmus, DA; Popiel, I1
Brindley, PJ1
Awney, HA; Badawi, AF; Mostafa, MH1
Cioli, D; Novi, A; Pica-Mattoccia, L1
Badawi, AF1
Cioli, D; Moroni, R; Pica-Mattoccia, L; Southgate, VR; Tchuem Tchuenté, LA1
Cao, X; Guzman, M; LoVerde, PT; McHardy, SF; Rugel, A; Tarpley, RS; Taylor, AB1

Reviews

7 review(s) available for lucanthone hydrochloride and hycanthone

ArticleYear
Chemotherapy of Schistosomiasis mansoni.
    Advances in pharmacology and chemotherapy, 1977, Volume: 14

    Topics: Amphotericin B; Animals; Antimony; Chemosterilants; Drug Evaluation; Drug Evaluation, Preclinical; Eggs; Emetine; Humans; Hycanthone; Lucanthone; Naphthalenes; Niridazole; Nitrofurans; Organophosphorus Compounds; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Snails; Thiazoles; Thiophenes; Tubercidin

1977
Biochemical and pharmacological effects in relation to the mode of action of antischistosomal drugs.
    Biochemical pharmacology, 1979, Aug-15, Volume: 28, Issue:16

    Topics: Animals; Antimony; Carbohydrate Metabolism; Glycogen; Heterocyclic Compounds; Hycanthone; Neurotransmitter Agents; Niridazole; Oxamniquine; Schistosoma; Schistosomicides

1979
Genetic activities of hycanthone and some other antischistosomal drugs.
    Mutation research, 1978, Volume: 55, Issue:1

    Topics: Acrylamides; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophila; Genes, Dominant; Genes, Lethal; Humans; Hycanthone; Lucanthone; Mice; Mutagens; Mutation; Niridazole; Nitrofurans; Oxamniquine; Rabbits; Rats; Saccharomyces cerevisiae; Salmonella typhimurium; Schistosomicides; Species Specificity; Teratogens; Thioxanthenes; Trichlorfon

1978
Genetic activity spectra of some antischistosomal compounds, with particular emphasis on thioxanthenones and benzothiopyranoindazoles.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Alkylation; Animals; Carcinogens; Crossing Over, Genetic; DNA Repair; DNA Replication; Hycanthone; Indazoles; Mutagens; Mutation; Permeability; Polyamines; Pyrazoles; Schistosomicides; Thioxanthenes

1975
The chemotherapy of schistosomiasis.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazole; Oxamniquine; Praziquantel; Pyrazines; Schistosomiasis; Schistosomicides; Thiocyanates; Thiones; Thiophenes; Trichlorfon

1985
A review of the clinical pharmacology of hycanthone.
    Egyptian journal of bilharziasis, 1974, Volume: 1, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Africa; Animals; Blood Pressure; Body Temperature; Body Weight; Brazil; Cats; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Evaluation; Electrocardiography; Electroencephalography; Ethylenediamines; Female; Humans; Hycanthone; Infant; Injections, Intramuscular; Liver; Liver Function Tests; Male; Middle Aged; Schistosoma; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thioxanthenes

1974
Drug resistance to schistosomicides and other anthelmintics of medical significance.
    Acta tropica, 1994, Volume: 56, Issue:2-3

    Topics: Animals; Anthelmintics; Base Sequence; DNA Primers; Drug Resistance; Gene Rearrangement; Helminthiasis; Helminths; Humans; Hycanthone; Molecular Sequence Data; Schistosoma; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Structure-Activity Relationship

1994

Trials

2 trial(s) available for lucanthone hydrochloride and hycanthone

ArticleYear
The effect of a second dose of hycanthone alone and with progesterone caproate on the cure rate and the side reactions of hycanthone in the treatment of S. haematobium infected cases.
    Egyptian journal of bilharziasis, 1974, Volume: 1, Issue:1

    Topics: Adolescent; Blood Cell Count; Blood Proteins; Caproates; Child; Clinical Trials as Topic; Drug Synergism; Ethylenediamines; Feces; Female; Hemoglobinometry; Humans; Hycanthone; Injections, Intramuscular; Liver Function Tests; Male; Ovum; Parasite Egg Count; Progesterone; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Thioxanthenes; Urine

1974
Failure of targeted mass treatment to control schistosomiasis.
    Lancet (London, England), 1981, Jan-03, Volume: 1, Issue:8210

    Topics: Communicable Disease Control; Democratic Republic of the Congo; Feces; Humans; Hycanthone; Parasite Egg Count; Schistosoma mansoni; Schistosomiasis; Schistosomicides

1981

Other Studies

32 other study(ies) available for lucanthone hydrochloride and hycanthone

ArticleYear
[Specific treatment of urinary bilharziasis].
    Journal d'urologie et de nephrologie, 1977, Volume: 83 Suppl 2

    Topics: Drug Tolerance; Emetine; Humans; Hycanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlorfon; Urologic Diseases

1977
Current chemotherapy of schistosomiasis in Japan.
    The Southeast Asian journal of tropical medicine and public health, 1976, Volume: 7, Issue:2

    Topics: 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole; Adult; Animals; Antimony; Child; Cricetinae; Humans; Hycanthone; Mice; Niridazole; Rats; Schistosomiasis; Schistosomicides; Tubercidin

1976
Mutagenic evaluation of antischistosomal drugs and their derivatives in Neurospora crassa.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Hycanthone; Lucanthone; Mutagens; Mutation; Neurospora; Neurospora crassa; Schistosomicides

1975
Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Female; Hycanthone; Indazoles; Liver; Liver Neoplasms; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thioxanthenes

1976
Mutagenic activities in vitro and in vivo of five antischistosomal compounds.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: Animals; Female; Hycanthone; Mice; Microsomes, Liver; Mutagens; Oxamniquine; Salmonella typhimurium; Schistosoma mansoni; Schistosomicides; Trichlorfon

1977
[Experimental studies on the schistosomicidal activity of the aminobenzaldehyde derivative 80.647 (author's transl)].
    Tropenmedizin und Parasitologie, 1977, Volume: 28, Issue:1

    Topics: Animals; Benzaldehydes; Cricetinae; Haplorhini; Hycanthone; Mesocricetus; Mice; Niridazole; Piperazines; Schistosoma; Schistosoma haematobium; Schistosoma mansoni; Schistosomicides

1977
[Medical treatment of urogenital bilharziasis].
    al-Maghrib al-tibbi. Maroc medical, 1979, Volume: 1, Issue:3

    Topics: Antimony; Humans; Hycanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlorfon

1979
Activity of known antischistosomal agents on early-developing forms of Schistosoma mansoni.
    The Journal of parasitology, 1975, Volume: 61, Issue:2

    Topics: Animals; Antimony; Diethylamines; Edetic Acid; Hycanthone; Lithium; Lucanthone; Mice; Oxamniquine; Schistosomiasis; Schistosomicides; Thiomalates; Toluidines; Trichlorfon

1975
Anticholinergic properties of the antischistosomal drug hycanthone.
    The American journal of tropical medicine and hygiene, 1975, Volume: 24, Issue:5

    Topics: Animals; Cattle; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Hycanthone; Lucanthone; Mice; Motor Activity; Parasympatholytics; Rats; Schistosoma mansoni; Schistosomicides; Snails; Thioxanthenes

1975
Clinically available antischistosomal drugs.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Antimony; Humans; Hycanthone; Lucanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlorfon

1975
Dissociation of mutagenic and other toxic properties from schistosomicides.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Animals; Cyclic N-Oxides; Humans; Hycanthone; Mice; Mutagens; Oxidation-Reduction; Rats; Salmonella; Schistosomicides; Thiazoles

1975
Sex differences in micronucleus induction with hycanthone methanesulfonate in bone marrow cells of mice.
    Mutation research, 1992, Volume: 283, Issue:4

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Dose-Response Relationship, Drug; Female; Hycanthone; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Mutagens; Schistosomicides; Sex Characteristics; Sex Factors

1992
Schistosoma mansoni: chemotherapy of infections of different ages.
    Experimental parasitology, 1986, Volume: 61, Issue:3

    Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thiocyanates; Time Factors

1986
The influence of anti-parasitic therapy on the course of the glomerulopathy associated with Schistosomiasis mansoni.
    Clinical nephrology, 1987, Volume: 27, Issue:5

    Topics: Humans; Hycanthone; Kidney; Kidney Diseases; Oxamniquine; Schistosomiasis mansoni; Schistosomicides

1987
Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel.
    Memorias do Instituto Oswaldo Cruz, 1987, Volume: 82 Suppl 4

    Topics: Animals; Antibodies, Helminth; Antibody-Dependent Cell Cytotoxicity; Drug Resistance; Hycanthone; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thioxanthenes

1987
Preparation and antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Antineoplastic Agents; Hycanthone; Indicators and Reagents; Leukemia P388; Leukemia, Experimental; Magnetic Resonance Spectroscopy; Mice; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship; Thioxanthenes

1988
Antimuscarinic activities of hycanthone analogs: possible relationship with animal toxicity.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: alpha-Amylases; Animals; Carbachol; Guinea Pigs; Hycanthone; Ileum; In Vitro Techniques; Lethal Dose 50; Male; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Schistosomicides; Structure-Activity Relationship; Thioxanthenes

1986
Schistosomicides and DNA functioning.
    Biochemical Society transactions, 1987, Volume: 15, Issue:1

    Topics: Animals; DNA; Female; Hycanthone; Male; Oxamniquine; Schistosoma; Schistosomicides; Structure-Activity Relationship

1987
[Genetic and molecular aspects of drug resistance in Schistosoma mansoni].
    Annali dell'Istituto superiore di sanita, 1986, Volume: 22, Issue:1

    Topics: Animals; Carbamates; Drug Resistance; HeLa Cells; Humans; Hycanthone; Oxamniquine; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship

1986
Studies on the mode of action of oxamniquine and related schistosomicidal drugs.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Female; Hycanthone; Lucanthone; Male; Mice; Nitroquinolines; Oxamniquine; Rats; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides

1985
Evidence for the mode of antischistosomal action of hycanthone.
    Life sciences, 1985, Jul-15, Volume: 37, Issue:2

    Topics: Alkylating Agents; Animals; Biotransformation; DNA; Drug Resistance; Female; Hycanthone; Male; Mice; Mutation; Rats; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides; Thioxanthenes

1985
Hycanthone: a review of its experimental chemotherapy, pharmacology and toxicology.
    Egyptian journal of bilharziasis, 1974, Volume: 1, Issue:2

    Topics: Animals; Cats; Cricetinae; Dogs; Drug Tolerance; Female; Haplorhini; Humans; Hycanthone; Male; Mice; Pregnancy; Rabbits; Rats; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Snails; Thioxanthenes

1974
Therapeutic evaluation of hycanthone in school children in rural endemic area in Egypt.
    Egyptian journal of bilharziasis, 1974, Volume: 1, Issue:1

    Topics: Adolescent; Age Factors; Child; Drug Evaluation; Egypt; Environmental Exposure; Ethylenediamines; Female; Follow-Up Studies; Humans; Hycanthone; Injections, Intramuscular; Male; Parasite Egg Count; Rural Health; Rural Population; Schistosoma haematobium; Schistosomiasis; Schistosomicides; School Health Services; Sex Factors; Snails; Thioxanthenes; Urine

1974
Schistosoma mansoni: an in vivo study of drug-induced autophagy in the gastrodermis.
    Journal of helminthology, 1984, Volume: 58, Issue:1

    Topics: Animals; Antimony; Hycanthone; Lucanthone; Mice; Niridazole; Organometallic Compounds; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Succimer

1984
Synthesis of new 8-(5-substituted amino-1,3,4-oxadiazol-2-yl) and 8-(5-substituted amino-1,3,4-thiadiazol-2-yl) methoxyquinolines with antibilharzial activity.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:3

    Topics: Animals; Hycanthone; Hydroxyquinolines; Intestine, Small; Liver; Mice; Oxadiazoles; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiadiazoles

1984
Factors affecting the acquisition of resistance against Schistosoma mansoni in the mouse. V. Reduction in the degree of resistance to reinfection after chemotherapeutic elimination of recently patent primary infections.
    Journal of helminthology, 1980, Volume: 54, Issue:1

    Topics: Animals; Antimony Potassium Tartrate; Hycanthone; Immunity, Active; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomicides

1980
Schistosoma mansoni: drug induced changes in the cell population of the vitelline gland.
    Experimental parasitology, 1980, Volume: 50, Issue:2

    Topics: Animals; Cell Differentiation; Cell Division; Female; Genitalia, Female; Hycanthone; Lucanthone; Schistosoma mansoni; Schistosomicides; Thioxanthenes

1980
Formation of promutagenic methylation damage in tissue-DNA of mice treated with antischistosomal agents.
    Cancer letters, 1993, Dec-20, Volume: 75, Issue:3

    Topics: Alkylation; Animals; Deoxyguanosine; DNA; DNA Damage; Hycanthone; Kidney; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Oxamniquine; Schistosomicides; Spleen; Trichlorfon; Urinary Bladder

1993
Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections.
    Parasitology research, 1997, Volume: 83, Issue:7

    Topics: Animals; Biotransformation; Hycanthone; Macromolecular Substances; Male; Oxamniquine; Schistosoma haematobium; Schistosoma mansoni; Schistosomicides; Species Specificity

1997
O6-methylguanine and O6-methylguanine-DNA [corrected] methyltransferase activity in tissues of BDF-1 mice treated with antiparasitic drugs.
    Toxicology letters, 1998, Volume: 94, Issue:3

    Topics: Animals; DNA Damage; Guanine; Hycanthone; Intestines; Liver; Male; Mice; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Oxamniquine; Schistosomicides; Trichlorfon; Urinary Bladder

1998
Changes of mate occur in Schistosoma mansoni.
    Parasitology, 2000, Volume: 120 ( Pt 5)

    Topics: Animals; Biomphalaria; Drug Resistance; Female; Hycanthone; Male; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Sexual Behavior, Animal

2000
Molecular basis for hycanthone drug action in schistosome parasites.
    Molecular and biochemical parasitology, 2020, Volume: 236

    Topics: Animals; Crystallization; Crystallography, X-Ray; Drug Design; Drug Resistance; Humans; Hycanthone; Oxamniquine; Praziquantel; Protein Binding; Recombinant Proteins; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sulfotransferases

2020