Page last updated: 2024-09-04

lubiprostone and loperamide

lubiprostone has been researched along with loperamide in 3 studies

Compound Research Comparison

Studies
(lubiprostone)
Trials
(lubiprostone)
Recent Studies (post-2010)
(lubiprostone)
Studies
(loperamide)
Trials
(loperamide)
Recent Studies (post-2010) (loperamide)
214381341,358196488

Protein Interaction Comparison

ProteinTaxonomylubiprostone (IC50)loperamide (IC50)
Cocaine esteraseHomo sapiens (human)5.7
Beta-2 adrenergic receptorHomo sapiens (human)3.005
ATP-dependent translocase ABCB1Homo sapiens (human)2.5
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.27
Cytochrome P450 2D6Homo sapiens (human)2
Histamine H2 receptorHomo sapiens (human)3.081
Sodium-dependent serotonin transporterHomo sapiens (human)2.202
Mu-type opioid receptorHomo sapiens (human)0.0014
D(3) dopamine receptorHomo sapiens (human)1.337
Delta-type opioid receptorHomo sapiens (human)0.896
Kappa-type opioid receptorHomo sapiens (human)3.125
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.105
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.033
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.239
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.628

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Sood, MR1
Morgan, B1

Reviews

1 review(s) available for lubiprostone and loperamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for lubiprostone and loperamide

ArticleYear
Treatment approaches to irritable bowel syndrome.
    Pediatric annals, 2009, Volume: 38, Issue:5

    Topics: Alprostadil; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Behavior Therapy; Child; Child, Preschool; Clinical Trials as Topic; Cognitive Behavioral Therapy; Dietary Fiber; Gastrointestinal Agents; Humans; Irritable Bowel Syndrome; Loperamide; Lubiprostone; Melatonin; Parasympatholytics; Pediatrics; Physician's Role; Primary Health Care; Probiotics; Treatment Outcome

2009
Drug development: A healthy pipeline.
    Nature, 2016, 05-19, Volume: 533, Issue:7603

    Topics: Animals; Benzimidazoles; Benzofurans; Bile Acids and Salts; Carbolines; Colesevelam Hydrochloride; Colestipol; Disease Models, Animal; Enteric Nervous System; Female; Humans; Imidazoles; Indoles; Irritable Bowel Syndrome; Loperamide; Lubiprostone; Male; Mice; Natriuretic Peptides; Peptides; Phenylalanine; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Rifamycins; Rifaximin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Visceral Pain

2016