Page last updated: 2024-09-04

lubazodone hydrochloride and 8-hydroxy-2-(di-n-propylamino)tetralin

lubazodone hydrochloride has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 2 studies

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

Compound Research Comparison

Studies
(lubazodone hydrochloride)
Trials
(lubazodone hydrochloride)
Recent Studies (post-2010)
(lubazodone hydrochloride)
Studies
(8-hydroxy-2-(di-n-propylamino)tetralin)
Trials
(8-hydroxy-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
12013,5307389

Protein Interaction Comparison

ProteinTaxonomylubazodone hydrochloride (IC50)8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.0012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0032
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorBos taurus (cattle)0.8
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.81
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorRattus norvegicus (Norway rat)2.8959
Lysosomal alpha-glucosidaseBos taurus (cattle)0.0021

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blier, P; De Montigny, C; Dong, J1
Blier, P; Szabo, ST1

Other Studies

2 other study(ies) available for lubazodone hydrochloride and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Assessment of the serotonin reuptake blocking property of YM992: electrophysiological studies in the rat hippocampus and dorsal raphe.
    Synapse (New York, N.Y.), 1999, Dec-15, Volume: 34, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Fluvoxamine; Hippocampus; Injections, Intravenous; Lysergic Acid Diethylamide; Male; Morpholines; Neurons; Piperazines; Prefrontal Cortex; Pyramidal Cells; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission

1999
Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Clonidine; Electrophysiology; Idazoxan; Male; Morpholines; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists

2002