Page last updated: 2024-09-05

lu 25-109 and sabcomeline

lu 25-109 has been researched along with sabcomeline in 2 studies

Compound Research Comparison

Studies (lu 25-109)	Trials (lu 25-109)	Recent Studies (post-2010) (lu 25-109)	Studies (sabcomeline)	Trials (sabcomeline)	Recent Studies (post-2010) (sabcomeline)
14	2	1	15	0	2

Protein Interaction Comparison

Protein	Taxonomy	sabcomeline (IC50)
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	0.18
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	0.09
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	0.17
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	0.06
Muscarinic acetylcholine receptor	Cavia porcellus (domestic guinea pig)	0.17

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Allen, JR; Bures, MG; Bymaster, F; Croy, CH; Evans, D; Felder, CC; Hansen, MM; Hitchcock, SA; Hoogestraat, PJ; Jamison, JA; Liu, B; McKinzie, DL; Okha-Mokube, FM; Rao, Z; Stratford, RE; Stuart Gregory, G; Turner, W; Watt, ML	1
Bymaster, FP; Calligaro, DO; Carter, PA; DeLapp, N; Fink-Jensen, A; Jeppesen, L; Mitch, CH; Peters, SC; Rimvall, K; Sauerberg, P; Shannon, HE; Sheardown, MJ; Ward, JS; Whitesitt, CA; Zhang, W	1

Other Studies

2 other study(ies) available for lu 25-109 and sabcomeline

Article	Year
Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists. Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19 Topics: Amides; Animals; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Rats; Receptor, Muscarinic M1; Structure-Activity Relationship	2015
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects. Brain research, 1998, Jun-08, Volume: 795, Issue:1-2 Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Cholinesterase Inhibitors; Dihydropyridines; Dose-Response Relationship, Drug; Hydrolysis; Hypothermia; Imines; Lithium; Male; Mice; Mice, Inbred Strains; Muscarinic Agonists; Oximes; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Pilocarpine; Pyridines; Quinuclidines; Radioligand Assay; Salivation; Tacrine; Tetrazoles; Thiadiazoles; Tremor	1998

Article

Year

Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists.

Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

Topics: Amides; Animals; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Rats; Receptor, Muscarinic M1; Structure-Activity Relationship

2015

Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.

Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Cholinesterase Inhibitors; Dihydropyridines; Dose-Response Relationship, Drug; Hydrolysis; Hypothermia; Imines; Lithium; Male; Mice; Mice, Inbred Strains; Muscarinic Agonists; Oximes; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Pilocarpine; Pyridines; Quinuclidines; Radioligand Assay; Salivation; Tacrine; Tetrazoles; Thiadiazoles; Tremor

1998