lu 25-109 has been researched along with carbachol in 3 studies
| Studies (lu 25-109) | Trials (lu 25-109) | Recent Studies (post-2010) (lu 25-109) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 14 | 2 | 1 | 13,918 | 81 | 968 |
| Protein | Taxonomy | lu 25-109 (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bøgesø, KP; Frederiksen, K; Løve Lembøl, H; Meier, E; Moltzen, EK; Pedersen, H; Sánchez, C | 1 |
| Anderton, BH; Dayanandan, R; Forlenza, OV; Lovestone, S; Olesen, OF; Spink, JM | 1 |
| Andersson, K-; Larsson, B; Sandberg, B; Waldeck, K | 1 |
3 other study(ies) available for lu 25-109 and carbachol
| Article | Year |
|---|---|
Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity.
Topics: Animals; Arecoline; Female; Guinea Pigs; Male; Mice; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles; Triazoles | 1994 |
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Lithium Chloride; Microtubules; Muscarinic Agonists; Neurons; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; tau Proteins; Tetrazoles; Thiadiazoles | 2000 |
Actions of the new antimuscarinic compound Lu 25-109 on isolated human and pig detrusor.
Topics: Adult; Aged; Animals; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Electric Stimulation; Humans; In Vitro Techniques; Isometric Contraction; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Parotid Gland; Pyridines; Quinuclidinyl Benzilate; Swine; Tetrazoles; Urinary Bladder | 2002 |