Compounds > loxtidine
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loxtidine and gastrins

loxtidine has been researched along with gastrins in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (83.33)18.2507
2000's2 (11.11)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldenring, JR; Kumar, R; Modlin, IM; Nangia, A; Pasikhov, D; Soroka, CJ1
Brenna, E; Kristensen, A; Sandvik, AK; Schulze Søgnen, B; Waldum, HL1
Calam, J; Coates, ME; Goodlad, RA; Lee, CY; Ratcliffe, B; Stamp, GW; Wright, NA1
Selway, SA1
Burlinson, B; Gatehouse, DG; Jackson, MR; Morriss, S; Tweats, DJ1
Darr, UM; Lawton, GP; Modlin, IM; Soroka, CJ; Tang, LH; Zhu, ZH1
Ahlman, H; Dahlström, A; Modlin, IM; Nilsson, O; Theodorsson, E; Wängberg, B1
Brenna, E; de Pont, JJ; Klaassen, CH; Swarts, HG; Waldum, HL1
Ahlman, H; Kölby, L; Nilsson, O; Wängberg, B; Wank, SA1
Ahlman, H; Granérus, G; Kölby, L; Modlin, IM; Nilsson, O; Theodorsson, E; Wängberg, B1
Goldenring, JR; Kidd, M; Lawton, GP; Miu, K; Modlin, IM; Pasikhov, D; Powers, RE; Soroka, CJ; Tang, LH; Zhu, Z1
Bortecen, KH; Efstathiou, JA; Kidd, M; Luque, EA; Modlin, IM; Tang, LH; Tarasova, NI1
Bortecen, KH; Efstathiou, JA; Kidd, M; Luque, EA; Miu, K; Modlin, IM; Tang, LH1
Nimura, H; Takayama, S; Tsutsumi, J1
Ahlman, H; Kölby, L; Modlin, IM; Nilsson, O; Theodorsson, E; Wängberg, B1
Bakkelund, KE; Fossmark, R; Kawase, S; Martinsen, TC; Waldum, HL1
Carlson, JE; Cui, G; Dockray, GJ; Fox, JG; Frederick, DM; Ge, Z; Houghton, J; Rogers, AB; Takaishi, S; Varro, A; Wang, TC; Whary, MT1
Chen, D; Fossmark, R; Kidd, M; Kodama, Y; Modlin, IM; Vigen, RA; Viset, T; Waldum, H; Wang, TC; Zhao, CM1

Other Studies

18 other study(ies) available for loxtidine and gastrins

ArticleYear
Gastrin-dependent inhibitory effects of octreotide on the genesis of gastric ECLomas.
    Surgery, 1992, Volume: 112, Issue:6

    Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Division; Enterochromaffin Cells; Female; Gastrins; Histamine H2 Antagonists; Hyperplasia; Male; Muridae; Octreotide; Stomach; Stomach Neoplasms; Triazoles

1992
Effects on the rat oxyntic mucosa of the histamine2-antagonist loxtidine and the H+, K(+)-ATPase inhibitor omeprazole.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:3

    Topics: Animals; Drug Combinations; Female; Gastrins; Histamine; Omeprazole; Parietal Cells, Gastric; Rats; Rats, Inbred Strains; Triazoles

1992
Achlorhydria-induced hypergastrinaemia: the role of bacteria.
    Clinical science (London, England : 1979), 1991, Volume: 80, Issue:4

    Topics: Achlorhydria; Animals; Dose-Response Relationship, Drug; Eosinophils; Gastric Acid; Gastric Mucosa; Gastrins; Germ-Free Life; Helicobacter pylori; Histamine H2 Antagonists; Leukocyte Count; Rats; Rats, Inbred Strains; Triazoles

1991
Potential hazards of long-term acid suppression.
    Scandinavian journal of gastroenterology. Supplement, 1990, Volume: 178

    Topics: Animals; Carcinoid Tumor; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Humans; Hyperplasia; Male; Mice; Omeprazole; Rats; Stomach Neoplasms; Time Factors; Triazoles

1990
Uptake of tritiated thymidine by cells of the rat gastric mucosa after exposure to loxtidine or omeprazole.
    Mutagenesis, 1991, Volume: 6, Issue:1

    Topics: Administration, Oral; Animals; Autoradiography; Cell Separation; DNA; DNA Replication; Gastric Mucosa; Gastrins; Male; Methylnitronitrosoguanidine; Mutagenicity Tests; Omeprazole; Pronase; Rats; Rats, Inbred Strains; Thymidine; Triazoles

1991
Enterochromaffin-like cell pathobiology of mastomys.
    Annals of the New York Academy of Sciences, 1994, Sep-15, Volume: 733

    Topics: Animals; Chromogranins; Cyproheptadine; Enterochromaffin Cells; Estradiol; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Histamine Release; Hyperplasia; Muridae; Neuroendocrine Tumors; Octreotide; Tamoxifen; Triazoles

1994
Are enterochromaffinlike cell tumours reversible? An experimental study on gastric carcinoids induced in Mastomys by histamine2-receptor blockade.
    Regulatory peptides, 1995, Mar-07, Volume: 56, Issue:1

    Topics: Animals; Carcinoid Tumor; Cell Count; Cell Division; Cell Transformation, Neoplastic; Enterochromaffin Cells; Female; Gastrins; Histamine; Histamine H2 Antagonists; Hyperplasia; Male; Muridae; Parietal Cells, Gastric; Stomach Neoplasms; Triazoles

1995
Evaluation of the trophic effect of longterm treatment with the histamine H2 receptor antagonist loxtidine on rat oxyntic mucosa by differential counting of dispersed cells.
    Gut, 1994, Volume: 35, Issue:11

    Topics: Animals; Cell Count; Drug Administration Schedule; Female; Gastric Mucosa; Gastrins; H(+)-K(+)-Exchanging ATPase; Histamine H2 Antagonists; Organ Size; Parietal Cells, Gastric; Rats; Rats, Sprague-Dawley; Triazoles

1994
Expression of CCK-A and CCK-B/gastrin receptors in enterochromaffin-like cell carcinoids of Mastomys natalensis.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Animals; Blotting, Northern; Carcinogens; Carcinoid Tumor; Chromaffin System; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Muridae; Receptors, Cholecystokinin; Reference Values; Stomach; Stomach Neoplasms; Triazoles

1994
Histidine decarboxylase expression and histamine metabolism in gastric oxyntic mucosa during hypergastrinemia and carcinoid tumor formation.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: Animals; Carcinoid Tumor; Female; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Histamine Release; Histidine Decarboxylase; Male; Muridae; Parietal Cells, Gastric; RNA, Messenger; Stomach Neoplasms; Time Factors; Tissue Distribution; Triazoles

1996
Evidence for a regulatory role for histamine in gastric enterochromaffin-like cell proliferation induced by hypergastrinemia.
    Digestion, 1996, Volume: 57, Issue:5

    Topics: Animals; Cell Division; Chromogranins; DNA; Enterochromaffin Cells; Female; Gastric Mucosa; Gastrins; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hyperplasia; In Vitro Techniques; Male; Muridae; Terfenadine; Triazoles

1996
Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent.
    Regulatory peptides, 1997, Sep-26, Volume: 72, Issue:1

    Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Enterochromaffin Cells; Female; Gastrins; Gene Expression Regulation, Neoplastic; Histamine H2 Antagonists; Immunohistochemistry; Male; Muridae; Phosphorylation; Phosphoserine; Phosphotyrosine; Polymerase Chain Reaction; Receptors, Cholecystokinin; RNA, Messenger; Stomach Neoplasms; Triazoles

1997
Gastrin-regulated expression of p53 in transformed enterochromaffin-like cells in the African rodent mastomys.
    Journal of clinical gastroenterology, 1998, Volume: 27 Suppl 1

    Topics: Amino Acid Sequence; Animals; Blotting, Southern; Blotting, Western; Cell Transformation, Neoplastic; DNA Primers; DNA, Neoplasm; Enterochromaffin-like Cells; Gastrins; Gene Expression Regulation, Neoplastic; Genes, p53; Histamine H2 Antagonists; Immunohistochemistry; Molecular Sequence Data; Muridae; Mutation; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Triazoles; Tumor Suppressor Protein p53

1998
[Biochemical and immunohistological changes in the gastric mucosa of rats with long-term administration of histamine H2-receptor antagonist].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1998, Volume: 95, Issue:12

    Topics: Animals; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Male; Ornithine Decarboxylase; Peptic Ulcer; Polyamines; Precancerous Conditions; Rats; Rats, Wistar; Stomach Neoplasms; Triazoles

1998
Altered influence of CCK-B/gastrin receptors on HDC expression in ECL cells after neoplastic transformation.
    Regulatory peptides, 1999, Dec-23, Volume: 85, Issue:2-3

    Topics: Animals; Benzodiazepines; Carcinoid Tumor; Cell Transformation, Neoplastic; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Gene Expression; Histamine H2 Antagonists; Histidine Decarboxylase; Hormone Antagonists; Humans; Muridae; Receptors, Cholecystokinin; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Triazoles

1999
ECL-cell derived gastric cancer in male cotton rats dosed with the H2-blocker loxtidine.
    Cancer research, 2004, May-15, Volume: 64, Issue:10

    Topics: Animals; Enterochromaffin-like Cells; Female; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Immunohistochemistry; Male; Organ Size; Rats; Sigmodontinae; Stomach; Stomach Neoplasms; Triazoles

2004
Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.
    Gastroenterology, 2005, Volume: 128, Issue:7

    Topics: Achlorhydria; Animals; Atrophy; Benzodiazepinones; Disease Models, Animal; Gastrins; Helicobacter felis; Helicobacter Infections; Histamine H2 Antagonists; Male; Mice; Mice, Transgenic; Phenylurea Compounds; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Histamine H2; Stomach Neoplasms; Triazoles

2005
Immunohistochemical evidence for an impairment of autophagy in tumorigenesis of gastric carcinoids and adenocarcinomas in rodent models and patients.
    Histology and histopathology, 2013, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Biomarkers, Tumor; Carcinoid Tumor; Female; Gastric Mucosa; Gastrins; Humans; Immunohistochemistry; Insulin; Male; Membrane Proteins; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Middle Aged; Murinae; Promoter Regions, Genetic; Sigmodontinae; Stomach Neoplasms; Triazoles

2013