loxoprofen has been researched along with dinoprostone in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endo, T; Fukumura, T; Matsui, H; Mizushima, Y; Nakagawa, T; Uemura, H; Yanagawa, A | 1 |
| Asami, M; Iizuka, Y; Kojima, T; Matsuda, K; Sugimoto, M | 1 |
| Arakawa, T; Fukuda, T; Higuchi, K; Kobayashi, K; Nakagawa, K; Tominaga, K; Watanabe, T | 1 |
| Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M | 1 |
| Kawatani, M; Saito, M; Shinozaki, S | 1 |
| Gierse, JK; Kimoto, A; Noguchi, M; Nozaki, K; Sasamata, M; Walker, MC; Zweifel, BS | 1 |
| Kikuchi, S; Konno, S; Sekiguchi, M; Shirasaka, M | 1 |
| Akino, H; Aoki, Y; Imamura, Y; Ito, H; Matsuta, Y; Miwa, Y; Nagase, K; Oyama, N; Shioyama, R; Yokoyama, O | 1 |
| de Souza, SL; Grisi, MF; Novaes, AB; Palioto, DB; Pereira, LB; Pinho, Mde N; Taba, M | 1 |
| Arai, I; Futaki, N; Harada, M; Hashimoto, Y; Honma, Y; Hoshi, K; Nakaike, S; Sugimoto, M | 1 |
| Hashizume, M; Koike, N; Mihara, M; Suzuki, M; Yoshida, H | 1 |
| Araki, H; Araki, S; Isshiki, K; Kashiwagi, A; Kume, S; Kuwagata, S; Maegawa, H; Morita, Y; Soumura, M; Uzu, T; Yamahara, K | 1 |
| Amagase, K; Hayashi, S; Kitahirachi, E; Kurata, N; Nishimura, Y; Takeuchi, K; Yano, T | 1 |
| Amagase, K; Izumi, N; Takahira, Y; Takeuchi, K; Wada, T | 1 |
| Fukumoto, A; Hori, M; Kaku, S; Matsumoto, H; Tajima, K; Toda, Y | 1 |
3 trial(s) available for loxoprofen and dinoprostone
| Article | Year |
|---|---|
Possible mechanisms of gastroduodenal mucosal damage in volunteers treated with nonsteroidal antiinflammatory drugs--the usefulness of prodrugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Digestive System; Dinoprostone; Double-Blind Method; Duodenal Diseases; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Gastrointestinal Diseases; Hexosamines; Humans; Hydrogen-Ion Concentration; Incidence; Indoleacetic Acids; Intestinal Mucosa; Japan; Male; Microcirculation; Phenylpropionates; Prodrugs; Regional Blood Flow | 1992 |
Short-term effect of COX-2 selective inhibitor as an adjunct for the treatment of periodontal disease: a clinical double-blind study in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Dental Plaque Index; Dental Scaling; Dinoprostone; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Periodontal Index; Periodontitis; Phenylpropionates; Time Factors | 2008 |
Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; Cystatin C; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprostone; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Phenylpropionates; Transdermal Patch; Treatment Outcome | 2014 |
12 other study(ies) available for loxoprofen and dinoprostone
| Article | Year |
|---|---|
Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Dinoprostone; Exudates and Transudates; Indomethacin; Inflammation; Leukocyte Count; Leukocytes; Male; Phenylpropionates; Pleurisy; Prodrugs; Prostaglandins; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Ulcerogenicity and effect on inhibition of prostaglandin generation of indometacin farnesil, a prodrug of indomethacin, in rat gastric mucosa: comparison with indomethacin or loxoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Epoprostenol; Gastric Mucosa; Indomethacin; Male; Phenylpropionates; Prodrugs; Prostaglandin Antagonists; Rats; Rats, Wistar; Stomach Ulcer | 1995 |
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones | 2004 |
Loxoprofen inhibits facilitated micturition reflex induced by acetic acid urinary bladder infusion of the rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cystitis; Dinoprostone; Male; Muscle Contraction; Phenylpropionates; Rats; Rats, Sprague-Dawley; Reflex; Urinary Bladder; Urination | 2005 |
Enzymologic and pharmacologic profile of loxoprofen sodium and its metabolites.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Enzyme-Linked Immunosorbent Assay; Foot; Male; Oxygen Consumption; Peroxidases; Phenylpropionates; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Thromboxane B2 | 2005 |
Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Contusions; Dinoprostone; Indomethacin; Inflammation; Ketoprofen; Male; Pain; Pain Threshold; Phenylacetates; Phenylpropionates; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sprains and Strains | 2008 |
Long-lasting breaches in the bladder epithelium lead to storage dysfunction with increase in bladder PGE2 levels in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cystitis, Interstitial; Dinoprostone; Disease Models, Animal; Female; Mast Cells; Permeability; Phenylpropionates; Protamines; Rats; Rats, Wistar; Time Factors; Up-Regulation; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urothelium | 2008 |
The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Celecoxib; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Extremities; Fever; Freund's Adjuvant; Hyperalgesia; Hypothalamus; Inflammation; Male; Pain Measurement; Phenylpropionates; Piroxicam; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Wistar; Sulfonamides | 2009 |
High molecular weight hyaluronic acid relieved joint pain and prevented the progression of cartilage degeneration in a rabbit osteoarthritis model after onset of arthritis.
Topics: Adjuvants, Immunologic; Analgesics; Animals; Animals, Inbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Dinoprostone; Disease Models, Animal; Disease Progression; Hyaluronic Acid; Male; Matrix Metalloproteinases; Molecular Weight; Osteoarthritis; Pain; Pain Measurement; Phenylpropionates; Rabbits; Stifle; Synovial Fluid | 2010 |
Cinacalcet, a calcimimetic, prevents nonsteroidal antiinflammatory drug-induced small intestinal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Load; Cinacalcet; Dinoprostone; Enterobacteriaceae; Intestinal Diseases; Intestine, Small; Male; Mucin-2; Naphthalenes; Nitric Oxide Synthase Type II; Oligopeptides; Peroxidase; Phenylpropionates; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; RNA, Messenger; Tumor Necrosis Factor-alpha | 2013 |
Importance of cyclooxygenase-1/prostacyclin in modulating gastric mucosal integrity under stress conditions.
Topics: Animals; Cold Temperature; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Gastric Mucosa; Gastrointestinal Hemorrhage; Gene Expression; Indomethacin; Male; Mice, Inbred C57BL; Phenylpropionates; Prostaglandins I; Pyrazoles; Receptors, Epoprostenol; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Stress, Physiological | 2014 |
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E
Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Gait; Ketoprofen; Male; Phenylpropionates; Rats; Synovial Fluid; Transdermal Patch | 2018 |