loxoprofen and diclofenac

loxoprofen has been researched along with diclofenac in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Endo, T; Fukumura, T; Matsui, H; Mizushima, Y; Nakagawa, T; Uemura, H; Yanagawa, A1
Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K1
Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M1
Chi, YM; Hashimoto, F; Kinjo, J; Nakamura, M; Nohara, T; Sakurada, S; Yan, WM; Yoshizawa, T; Zhao, XY1
Aburatani, K; Hide, M; Honda, S; Honjoh, T; Kaneko, S; Kohno, K; Matsuo, H; Mihara, S; Morita, E; Takahashi, H; Tsujino, Y1
Mizokami, Y1
Funahashi, Y; Gotoh, M; Hattori, R; Ishikawa, K; Ito, K; Ito, Y; Miyagawa, Y; Mizuno, M; Mizuno, T; Noda, Y; Suzuki, Y; Yamada, K1
Kato, T; Kinoshita, H; Miyoshi, H; Tanaka, H1
Kinoshita, Y; Miwa, H; Sugano, K; Takeuchi, T1
Fukaya, T; Hashimoto, K; Iwata, A; Kage, M; Kawasaki, Y; Matsubara, K; Nigami, H; Tanigawa, K1
Arimitsu, J; Hagihara, K; Hiyama, S; Iijima, H; Inoue, T; Kawai, S; Mukai, A; Nishida, T; Ogata, A; Shinzaki, S; Shiraishi, E; Takehara, T; Tsujii, M1
Fukazawa, H; Inoue, M; Kaneko, Y; Miyazaki, Y; Niki, M; Ohno, H; Tanabe, K; Umeyama, T; Urai, M1
Kanbayashi, Y; Konishi, H1
Kao Yang, YH; Kubota, K; Lai, EC; Man, KKC; Park, BJ; Pratt, N; Roughead, EE; Setoguchi, S; Shin, JY; Wong, ICK1
Hazama, K; Imai, T; Kosuge, Y; Ootsuka, S; Suzuki, S1

Trials

5 trial(s) available for loxoprofen and diclofenac

ArticleYear
Possible mechanisms of gastroduodenal mucosal damage in volunteers treated with nonsteroidal antiinflammatory drugs--the usefulness of prodrugs.
    The Journal of rheumatology, 1992, Volume: 19, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Digestive System; Dinoprostone; Double-Blind Method; Duodenal Diseases; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Gastrointestinal Diseases; Hexosamines; Humans; Hydrogen-Ion Concentration; Incidence; Indoleacetic Acids; Intestinal Mucosa; Japan; Male; Microcirculation; Phenylpropionates; Prodrugs; Regional Blood Flow

1992
Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on serum allergen levels after wheat ingestion.
    Journal of dermatological science, 2009, Volume: 53, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Female; Gliadin; Humans; Intestinal Absorption; Male; Meloxicam; Middle Aged; Phenylpropionates; Thiazines; Thiazoles; Wheat Hypersensitivity

2009
[Local instillation of 0.75% ropivacaine compared with intravenous fentanyl and flurbiprofen for postoperative analgesia following inguinal hernia repair in adults].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:10

    Topics: Aged; Aged, 80 and over; Amides; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fentanyl; Flurbiprofen; Hernia, Inguinal; Humans; Intraoperative Care; Middle Aged; Pain, Postoperative; Phenylpropionates; Ropivacaine

2012
Safety and efficacy of long-term esomeprazole 20 mg in Japanese patients with a history of peptic ulcer receiving daily non-steroidal anti-inflammatory drugs.
    BMC gastroenterology, 2013, Mar-26, Volume: 13

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Esomeprazole; Female; gamma-Glutamyltransferase; Headache; Humans; Japan; Liver Function Tests; Male; Meloxicam; Middle Aged; Osteoarthritis; Peptic Ulcer; Phenylpropionates; Proton Pump Inhibitors; Secondary Prevention; Spasm; Thiazines; Thiazoles; Time Factors

2013
Amelioration of small bowel injury by switching from nonselective nonsteroidal anti-inflammatory drugs to celecoxib in rheumatoid arthritis patients: a pilot study.
    Digestion, 2014, Volume: 89, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Capsule Endoscopy; Celecoxib; Cytokines; Diclofenac; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Phenylpropionates; Pilot Projects; Prospective Studies; Pyrazoles; Severity of Illness Index; Single-Blind Method; Sulfonamides

2014

Other Studies

11 other study(ies) available for loxoprofen and diclofenac

ArticleYear
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase Inhibitors; Diclofenac; Edema; Fever; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitrobenzenes; Pain; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides

1993
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:11

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones

2004
Anti-inflammatory activity of 4,4'-dihydroxy-alpha-truxillic acid.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclobutanes; Diclofenac; Female; Formaldehyde; Indomethacin; Inflammation; Male; Mutagenicity Tests; Pain Measurement; Phenylpropionates; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Stomach Ulcer; Uric Acid

2006
Efficacy and safety of rabeprazole in non-steroidal anti-inflammatory drug-induced ulcer in Japan.
    World journal of gastroenterology, 2009, Oct-28, Volume: 15, Issue:40

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Humans; Japan; Male; Middle Aged; Phenylpropionates; Piroxicam; Rabeprazole; Stomach Ulcer

2009
Short-term administration of diclofenac sodium affects renal function after laparoscopic radical nephrectomy in elderly patients.
    Japanese journal of clinical oncology, 2012, Volume: 42, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Kaplan-Meier Estimate; Kidney; Kidney Neoplasms; Laparoscopy; Male; Middle Aged; Nephrectomy; Phenylpropionates; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors

2012
Nonsteroidal anti-inflammatory drug-induced vanishing bile duct syndrome treated with plasmapheresis.
    Journal of pediatric gastroenterology and nutrition, 2013, Volume: 57, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bile Duct Diseases; Bile Ducts; Diclofenac; Female; Humans; Liver; Liver Failure; Phenylpropionates; Plasmapheresis; Syndrome; Treatment Outcome

2013
Potent drugs that attenuate anti-Candida albicans activity of fluconazole and their possible mechanisms of action.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:10

    Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Candida albicans; Candidiasis; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Fluconazole; Fungal Proteins; Gene Expression; Ibuprofen; Membrane Transport Proteins; Microbial Sensitivity Tests; Omeprazole; Phenylpropionates; Proton Pump Inhibitors

2014
Predictive Factors for NSAIDs-related Gastrointestinal Toxicity: Can COX-2 Selective Inhibtor Prevent it?.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:140

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Agents; Aspirin; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Diseases; Duodenal Ulcer; Endoscopy, Digestive System; Etodolac; Female; Humans; Logistic Models; Male; Middle Aged; Phenylpropionates; Protective Factors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Stomach Diseases; Stomach Ulcer

2015
Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: A multi-database, international cohort study.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Australia; Celecoxib; Databases, Factual; Diclofenac; Female; Follow-Up Studies; Gastrointestinal Diseases; Hong Kong; Hospitalization; Humans; Incidence; Japan; Male; Mefenamic Acid; Phenylpropionates; Republic of Korea; Taiwan

2018
Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER.
    Scientific reports, 2022, 02-16, Volume: 12, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Diclofenac; Drug Therapy, Combination; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Japan; Phenylpropionates; Quinolones; United States; United States Food and Drug Administration

2022