loxoprofen and celecoxib

loxoprofen has been researched along with celecoxib in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's17 (70.83)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Asano, T; Ishihara, T; Miyata, K; Mizushima, T; Okamoto, Y; Otsuka, M; Suemasu, S; Tanaka, K; Yamakawa, N1
Kimoto, A; Kobayashi, S; Miyata, K; Noguchi, M; Sasamata, M; Yoshino, T1
Kimoto, A; Miyata, K; Noguchi, M; Sasamata, M1
Arai, I; Futaki, N; Harada, M; Hashimoto, Y; Honma, Y; Hoshi, K; Nakaike, S; Sugimoto, M1
Arai, Y; Ishihara, T; Kimoto, A; Mizushima, T; Okamoto, Y; Otsuka, M; Suemasu, S; Tanaka, K; Yamakawa, N; Yokomizo, K1
Kawai, T; Nakamura, S; Sakamoto, C; Sugioka, T; Tabira, J1
Fujioka, T; Kodama, M; Matsunari, O; Mizukami, K; Murakami, K; Nakagawa, Y; Ogawa, R; Okimoto, T; Yamauchi, M1
Akita, R; Hachisu, M; Hori, K; Konishi, K; Tanaka, H1
Hanakawa, H; Komai, O; Ohta, S1
Arimitsu, J; Hagihara, K; Hiyama, S; Iijima, H; Inoue, T; Kawai, S; Mukai, A; Nishida, T; Ogata, A; Shinzaki, S; Shiraishi, E; Takehara, T; Tsujii, M1
Fukazawa, H; Inoue, M; Kaneko, Y; Miyazaki, Y; Niki, M; Ohno, H; Tanabe, K; Umeyama, T; Urai, M1
Danjo, A; Goto, M; Sano, N; Shimohira, D; Yamashita, Y1
Imura, T; Inoue, G; Miyagi, M; Nakazawa, T; Saito, W; Sekiguchi, H; Takahira, N; Takaso, M; Uchida, K1
Fujimori, S; Hanada, R; Hayashida, M; Ikushima, I; Sakamoto, C; Sakurai, T1
Itoh, M; Kimura, M; Nakagawa, T; Ogoshi, A; Onda, A1
Kanbayashi, Y; Konishi, H1
Ariki, M; Fukushima, N; Hirai, T; Miyahara, N; Yoshiga, A1
Kao Yang, YH; Kubota, K; Lai, EC; Man, KKC; Park, BJ; Pratt, N; Roughead, EE; Setoguchi, S; Shin, JY; Wong, ICK1
Akiyama, J; Fujimori, S; Hanada, R; Hayashida, M; Sakamoto, C; Sakurai, T1
Fujimori, S; Fukunaga, K; Hanada, R; Hayashida, M; Iwakiri, K; Kubo, M; Mushiroda, T; Sakamoto, C; Sakurai, T; Takahashi, A1
Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S1
Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S1
Inokuchi, S; Kimura, T; Kumagai, Y; Miyake, M; Okamoto, M; Okumura, Y; Takano, T1
Fukuma, Y; Iwamoto, T; Kobayashi, T; Kushima, Y; Matsumoto, M; Miyamoto, T; Nakamura, M; Sato, Y1

Trials

10 trial(s) available for loxoprofen and celecoxib

ArticleYear
Comparison of gastroduodenal ulcer incidence in healthy Japanese subjects taking celecoxib or loxoprofen evaluated by endoscopy: a placebo-controlled, double-blind 2-week study.
    Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Endoscopy, Gastrointestinal; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Phenylpropionates; Pyrazoles; Sulfonamides

2013
Evaluation of selective cyclooxygenase-2 inhibitor-induced small bowel injury: randomized cross-over study compared with loxoprofen in healthy subjects.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2013, Volume: 25, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Humans; Intestine, Small; Japan; Male; Middle Aged; Phenylpropionates; Pyrazoles; Sulfonamides

2013
Comparative study of the clinical efficacy of the selective cyclooxygenase-2 inhibitor celecoxib compared with loxoprofen in patients with frozen shoulder.
    Modern rheumatology, 2014, Volume: 24, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Male; Middle Aged; Pain Measurement; Phenylpropionates; Pyrazoles; Sulfonamides; Treatment Outcome

2014
Amelioration of small bowel injury by switching from nonselective nonsteroidal anti-inflammatory drugs to celecoxib in rheumatoid arthritis patients: a pilot study.
    Digestion, 2014, Volume: 89, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Capsule Endoscopy; Celecoxib; Cytokines; Diclofenac; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Phenylpropionates; Pilot Projects; Prospective Studies; Pyrazoles; Severity of Illness Index; Single-Blind Method; Sulfonamides

2014
A parallel-group comparison study of celecoxib with loxoprofen sodium in third mandibular molar extraction patients.
    International journal of oral and maxillofacial surgery, 2014, Volume: 43, Issue:12

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Male; Mandible; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Phenylpropionates; Pyrazoles; Sulfonamides; Surveys and Questionnaires; Tooth Extraction; Treatment Outcome

2014
Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2015, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Phenylpropionates; Postoperative Care; Retrospective Studies; Spinal Fusion; Treatment Outcome

2015
Celecoxib Monotherapy Maintained Small Intestinal Mucosa Better Compared With Loxoprofen Plus Lansoprazole Treatment: A Double-blind, Randomized, Controlled Trial.
    Journal of clinical gastroenterology, 2016, Volume: 50, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Hemoglobins; Humans; Intestinal Mucosa; Lansoprazole; Male; Middle Aged; Occult Blood; Phenylpropionates; Proton Pump Inhibitors

2016
Comparison of the effects of treatment with celecoxib, loxoprofen, and acetaminophen on postoperative acute pain after arthroscopic knee surgery: A randomized, parallel-group trial.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:2

    Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Pain Measurement; Pain, Postoperative; Phenylpropionates; Retrospective Studies; Treatment Outcome

2016
Repeatability of small bowel transit time in capsule endoscopy in healthy subjects.
    Bio-medical materials and engineering, 2018, Volume: 29, Issue:6

    Topics: Adult; Aged; Body Weight; Capsule Endoscopy; Celecoxib; Female; Gastrointestinal Transit; Healthy Volunteers; Humans; Intestinal Mucosa; Intestine, Small; Lansoprazole; Male; Middle Aged; Phenylpropionates; Reproducibility of Results; Stomach; Time Factors

2018
Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee.
    BMJ open, 2023, 02-10, Volume: 13, Issue:2

    Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Pain; Double-Blind Method; Humans; Multicenter Studies as Topic; Osteoarthritis, Hip; Osteoarthritis, Knee; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome

2023

Other Studies

14 other study(ies) available for loxoprofen and celecoxib

ArticleYear
Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Humans; Phenylpropionates; Rats; Stomach Ulcer; Structure-Activity Relationship

2012
Effect of celecoxib, a cyclooxygenase-2 inhibitor, on the pathophysiology of adjuvant arthritis in rat.
    European journal of pharmacology, 2005, Apr-25, Volume: 513, Issue:3

    Topics: Animals; Arthritis, Experimental; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hindlimb; Joints; Male; Mycobacterium; Pain; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Stomach Ulcer; Sulfonamides

2005
Micro-CT imaging analysis for the effect of celecoxib, a cyclooxygenase-2 inhibitor, on inflammatory bone destruction in adjuvant arthritis rats.
    Journal of bone and mineral metabolism, 2008, Volume: 26, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bone Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Image Processing, Computer-Assisted; Inflammation; Male; Organic Chemicals; Phenylpropionates; Pyrazoles; Rats; Rats, Inbred Lew; Sulfonamides; Tomography, X-Ray Computed

2008
The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Celecoxib; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Extremities; Fever; Freund's Adjuvant; Hyperalgesia; Hypothalamus; Inflammation; Male; Pain Measurement; Phenylpropionates; Piroxicam; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Wistar; Sulfonamides

2009
Low direct cytotoxicity of loxoprofen on gastric mucosal cells.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; Humans; Indomethacin; Necrosis; Permeability; Phenylpropionates; Pyrazoles; Stomach Neoplasms; Sulfonamides

2010
Fluvoxamine and celecoxib may have caused adverse events in an elderly patient.
    Psychiatry and clinical neurosciences, 2013, Volume: 67, Issue:5

    Topics: Aged, 80 and over; Alzheimer Disease; Amnesia; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Fluvoxamine; Humans; Mental Disorders; Phenylpropionates; Pyrazoles; Sulfonamides

2013
Potent drugs that attenuate anti-Candida albicans activity of fluconazole and their possible mechanisms of action.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:10

    Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Candida albicans; Candidiasis; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Fluconazole; Fungal Proteins; Gene Expression; Ibuprofen; Membrane Transport Proteins; Microbial Sensitivity Tests; Omeprazole; Phenylpropionates; Proton Pump Inhibitors

2014
Predictive Factors for NSAIDs-related Gastrointestinal Toxicity: Can COX-2 Selective Inhibtor Prevent it?.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:140

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Agents; Aspirin; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Diseases; Duodenal Ulcer; Endoscopy, Digestive System; Etodolac; Female; Humans; Logistic Models; Male; Middle Aged; Phenylpropionates; Protective Factors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Stomach Diseases; Stomach Ulcer

2015
A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy.
    Nihon Jibiinkoka Gakkai kaiho, 2016, Volume: 119, Issue:8

    Topics: Adult; Analgesics; Celecoxib; Female; Hemorrhage; Humans; Male; Pain, Postoperative; Phenylpropionates; Tonsillectomy; Young Adult

2016
Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: A multi-database, international cohort study.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Australia; Celecoxib; Databases, Factual; Diclofenac; Female; Follow-Up Studies; Gastrointestinal Diseases; Hong Kong; Hospitalization; Humans; Incidence; Japan; Male; Mefenamic Acid; Phenylpropionates; Republic of Korea; Taiwan

2018
Bactericidal/Permeability-Increasing Fold-Containing Family B Member 4 May Be Associated with NSAID-Induced Enteropathy.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Celecoxib; Female; Genome-Wide Association Study; Humans; Intercellular Signaling Peptides and Proteins; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Phenylpropionates; Phosphoproteins; Polymorphism, Single Nucleotide

2019
Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Aged; Aged, 80 and over; Celecoxib; Chronic Pain; Computer Simulation; Cost Savings; Cost-Benefit Analysis; Drug Costs; Drugs, Generic; Female; Gastrointestinal Diseases; Humans; Japan; Male; Markov Chains; Middle Aged; Models, Economic; Phenylpropionates; Quality-Adjusted Life Years; Risk Assessment

2021
Real-World Hepatic Safety of Oral Acetaminophen Versus Loxoprofen/Celecoxib: Using a Nationwide Electronic Medical Record Database.
    Journal of clinical pharmacology, 2023, Volume: 63, Issue:7

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Electronic Health Records; Humans; Liver

2023
TNFα-dependent mTOR activity is required for tenotomy-induced ectopic ossification in mice.
    Journal of bone and mineral metabolism, 2023, Volume: 41, Issue:5

    Topics: Achilles Tendon; Activities of Daily Living; Animals; Celecoxib; Cimetidine; Female; Humans; Male; Mice; Ossification, Heterotopic; Tenotomy; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2023