Page last updated: 2024-08-24

loxiglumide and cholecystokinin

loxiglumide has been researched along with cholecystokinin in 158 studies

Research

Studies (158)

TimeframeStudies, this research(%)All Research%
pre-199016 (10.13)18.7374
1990's130 (82.28)18.2507
2000's11 (6.96)29.6817
2010's1 (0.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adler, G; Beglinger, C; Delco, F; Gyr, K; Hildebrand, P; Luo, H; Werth, B1
Baum, F; Cantor, P; Choudhury, AR; Creutzfeldt, W; Ebert, R; Hoffmann, G; Nauck, MA; Schmidt, WE1
Chijiiwa, Y; Harada, N; Misawa, T; Nawata, H; Yoshinaga, M1
Jansen, JB; Jebbink, MC; Lamers, CB; Mooy, DM; Rovati, LC2
Schmidt, WE1
Jansen, JB; Jebbink, MC; Lamers, CB; Masclee, AA; Rovati, LC; Schipper, J; van der Kleij, FG1
Beglinger, C; Drewe, J; Gyr, K; Hildebrand, P; Ketterer, S; Luo, H1
Bekkering, M; Bonato, C; D'Amato, M; De Fazio, C; Festorazzi, S; Giacovelli, G; Malesci, A; Rovati, LC; Tacconi, M; Valentini, A1
Funakoshi, A; Kono, A; Shimazoe, T1
Bishop, LA; Black, JW; Gerskowitch, VP; Hull, RA; Shankley, NP1
Miyazaki, N; Saito, Y; Tomioka, M; Yamamoto, M2
Kurose, I; Miura, S; Nagata, H; Sekizuka, E; Serizawa, H; Suematsu, M; Tashiro, H; Tsuchiya, M; Yoshioka, M1
Funakoshi, A; Kono, A1
Lüthen, R; Niederau, C; Niederau, M; Rovati, L; Schwarzendrube, J; Strohmeyer, G1
Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Höcker, M; Nustede, R; Schafmayer, A; Schmidt, WE1
Beglinger, C; Drewe, J; Gadient, A; Rovati, LC1
Faber, S; Karaus, M; Niederau, C1
Green, GM; Hatta, Y; Nakano, I; Taguchi, S1
Almegård, B; Bill, A; Stjernschantz, J1
Adler, G; Beglinger, C; Dahmen, G; Katschinski, M; Koop, H; Nustede, R; Reinshagen, M1
Bauerfeind, P; Beglinger, C; Delco, F; Eberle, A; Gyr, K; Hasslocher, H; Hildebrand, P; Meier, R; Urscheler, N1
Adler, G; Arnold, R; Beglinger, C; Braun, U; Koop, I; Reinshagen, M; Rovati, L; Schafmayer, A1
Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Höcker, M; Nustede, R; Rovati, LC; Schleser, A; Schmidt, WE1
Berry, C; Johnston, S; Spencer, GS1
Bruley des Varannes, S; Cloarec, D; Dubois, A; Galmiche, JP1
Baba, N; Manabe, T; Nishimura, I; Tasi, Y; Tobe, T1
Adler, G; Arnold, R; Beckh, K; Göke, R; Koop, I; Ruff, W1
Beglinger, C; Fried, M; Jansen, JB; Keller, U; Lamers, CB; Schwizer, W1
Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Höcker, M; Nitsche, R; Nustede, R; Rovati, LC; Schleser, A; Schmidt, WE; Sostmann, H1
Karaus, M; Niederau, C1
Bennett, A; D'Amato, M; Stamford, IF1
Lüthen, R; Niederau, C; Niederau, M; Schwarzendrube, J1
Bangerter, U; Beglinger, C; Delco, F; Ensinck, JW; Hildebrand, P; Ketterer, S; Mossi, S1
Beglinger, C; Bischof-Delaloye, A; Erlacher, U; Fried, M; Harder, F; Jansen, JB; Koerfer, J; Lamers, CB; Löchner, C; Schwizer, W1
Chaussade, S1
Albrecht, C; Beglinger, C; Gyr, K; Hildebrand, P; Meier, R; Studer, B; Thumshirn, M1
Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Höcker, M; Nitsche, R; Nustede, R; Rovati, LC; Schafmayer, A; Schleser, A; Schmidt, WE1
Adler, G; Beglinger, C; Braun, U; Koop, I; Reinshagen, M; Schafmayer, A1
Biliotti, D; Bontempo, I; Corazziari, E; De Medici, A; Pallotta, N; Ricci, R; Torsoli, A1
Beglinger, C; Gyr, K; Hildebrand, P; Jansen, JB; Lamers, CB; Rovati, LC; Setnikar, I; Stalder, GA; Zuercher, M1
Bonato, C; De Fazio, C; Festorazzi, S; Malesci, A; Rovati, L; Setnikar, I; Tacconi, M; Valentini, A1
Baba, H; Fujimura, M; Toda, N1
Konturek, SJ; Kopp, B; Kwiecien, N; Obtulowicz, W; Oleksy, J; Rovati, L1
Fujii, M; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Douglas, BR; Jansen, JB; Jebbink, MC; Lamers, CB1
Fujii, M; Fujisawa, T; Itoh, H; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Barocelli, E; Grider, JR; Impicciatore, M; Makhlouf, GM; Morini, G1
Jansen, JB; Jebbink, MC; Lamers, CB; Masclee, AA1
Gabryelewicz, A; Konturek, SJ; Kulesza, E1
Grendell, JH; Niederau, C; Niederau, M; Strohmeyer, G1
Baba, S; Fujii, M; Fujisawa, T; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S2
Beglinger, C; Hildebrand, P; Jansen, JB; Meyer, BM; Rovati, LC; Stalder, GA; Werth, BA; Zach, D1
Adler, G; Beglinger, C; Dill, S; Meyer, B; Werth, B1
Chisté, R; Giacovelli, G; Rovati, LC; Setnikar, I1
Fujii, K; Kishimoto, M; Miyoshi, A1
Adler, G; Arnold, R; Göke, B; Koop, I; Reinshagen, M; Rovati, LC; Schafmayer, A1
Bogdal, J; Konturek, JW; Konturek, SJ; Kurek, A; Oleksy, J; Rovati, L1
Douglas, BR; Jansen, JB; Jebbink, MC; Lamers, CB; Tjon a Tham, RT1
Heintges, T; Niederau, C; Rovati, L; Strohmeyer, G1
Moriyoshi, Y; Shimizu, K; Shiratori, K; Takeuchi, T; Watanabe, S1
Chisté, R; Makovec, F; Rovati, LC; Setnikar, I; Warrington, SJ1
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Setnikar, I1
Beglinger, C; Gyr, K; Hildebrand, P; Köhler, E; Setnikar, I1
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Rovati, LA; Rovati, LC; Setnikar, I1
Domschke, W; Konturek, JW; Konturek, SJ2
Domschke, W; Gillessen, A; Konturek, JW; Konturek, SJ1
Kimura, I; Kimura, M; Wakasono, S1
Domschke, W; Gabryelewicz, A; Konturek, JW; Stoll, R1
Brzozowski, T; Drozdowicz, D; Konturek, SJ; Pytko-Polonczyk, J1
Funakoshi, A; Masuda, M; Miyasaka, K1
Itoh, H; Koide, M; Okabayashi, Y; Otsuki, M; Tani, S1
Bamba, T; Hosoda, S; Ishizuka, Y1
Otsuki, M; Watanabe, N2
Hayakawa, T; Kitagawa, M; Kondo, T; Naruse, S; Shibata, T; Tanikawa, M1
Chang, TM; Chey, WY; Kim, CD; Lee, KY1
Jansen, JB; Jebbink, MC; Lamers, CB; Lieverse, RJ; Masclee, AA; Rovati, LC1
Konturek, JW1
Funakoshi, A; Jimi, A; Mishima, Y; Miyasaka, K; Tomita, H1
Badiali, D; Cicala, M; Corazziari, E; Diacinti, D; Torsoli, A1
Gielkens, HA; Hopman, WP; Jansen, JB; Rovati, LC; Tangerman, A; van Schaik, A; Verhulst, ML1
Bergin, A; French, SJ; Read, NW; Rovati, L; Sepple, CP1
Fölsch, UR; Höcker, M; Hughes, J; Schmidt, WE1
Domschke, W; Gabryelewicz, A; Gutwinska-Konturek, M; Konturek, JW; Konturek, SJ1
Chey, WY; Imamura, M; Yamauchi, H1
Domschke, W; Konturek, JW; Konturek, SJ; Maczka, M; Stoll, R; Thor, P1
Chang, TM; Chey, WY; Shimizu, K; Shiratori, K; Takeuchi, T; Watanabe, S1
Chang, TM; Chey, WY; Dubois, A; Jin, HO; Lee, KY1
Aufderhaar, U; Bauerfeind, P; Beglinger, C; Burckhardt, B; Delco, F; Ensinck, JW; Gyr, K; Ketterer, S; Meier, R1
Creutzfeldt, W; Fölsch, UR; Holst, JJ; Nustede, R; Schenk, S; Schmidt, WE1
Chang, TM; Chey, WY; Lee, KY; Lee, YL; Moriyasu, M1
Mantovani, P; Milenov, K; Rakovska, A; Sgaragli, G; Valoti, M1
Imaeda, H; Kimura, H; Miura, S; Ohkubo, N; Serizawa, H; Toda, K; Tso, P; Tsuchiya, M; Yoshioka, M1
Beglinger, C; Drewe, J; Gutzwiller, JP; Hildebrand, P; Lauper, JZ; Rossi, L1
Jansen, JB; Lamers, CB; Lieverse, RJ; Masclee, AA; Rovati, LC1
Heintges, T; Lüthen, R; Niederau, C1
Beglinger, C1
Jansen, JB; Lamers, CB; Lieverse, RJ; Masclee, AA2
Domschke, W; Konturek, JW; Konturek, SJ; Stoll, R2
Jansen, JB; Jebbink, MC; Lamers, CB; Mooy, DM; Rovati, LC; van der Kleij, FG1
Fukumoto, M; Hayashi, H; Imamura, M; Kawabata, K; Manabe, T; Masai, Y; Morimoto, H; Nio, Y; Tsubono, M1
Baba, N; Hayashi, H; Hosokawa, Y; Kawabata, K; Manabe, T; Masai, Y; Morimoto, H; Nio, Y; Tseng, CC; Tsubono, M1
Jansen, JB; Lamers, CB; Masclee, AA; Rovati, LC1
Heindges, T; Mecklenbeck, W; Niederau, C1
Hamaoka, T; Hayakawa, T; Kitagawa, M; Kodaira, T; Kondo, T; Shibata, T; Tanikawa, M1
Jansen, JB; Lamers, CB; Lieverse, RJ; Masclee, AA; Rovati, LC; Samson, L; van de Zwan, A1
Domschke, W; Gutwinska-Konturek, M; Konturek, JW; Konturek, SJ; Stoll, R1
Funakoshi, A; Matsumoto, M; Miyasaka, K; Sazaki, N1
Funakoshi, A; Miyasaka, K; Nakamura, E; Teraoka, H1
Rakovska, A1
Fujii, M; Hasegawa, H; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Shirohara, H1
Brotschi, EA; Hilbinger, CL; Kahl, EA; Midis, NA; Vaules, WA1
Arii, S; Funaki, N; Imamura, M; Imamura, T; Kohmoto, M; Ohshio, G; Okada, N; Sasaoki, T; Tanaka, J; Tanaka, T; Wang, ZH; Yoshida, M1
Inoue, K; Kubota, Y; Ogura, M1
Bielański, W; Domschke, W; Konturek, JW; Konturek, SJ1
Beglinger, C; Hartel, M; Niebergall-Roth, E; Riepl, RL; Singer, MV; Teyssen, S; Wetzel, D1
Kimura, T; Nakano, I; Nawata, H; Song, W; Yamaguchi, H1
Arai, M; Mitamura, K; Omachi, H; Tsubo, K1
Arnold, R; Begliner, C; D'Amato, M; Katschinski, M; Langbein, S; Schirra, J; Wank, U1
Bosshammer, A; Koop, H; Koop, I; Scheibner, J; Schindler, M; Stange, E1
Baintner, K; Bardocz, S; Ewen, SW; Gelencsér, E; Grant, G; Pusztai, A1
Abergel, A; Bommelaer, G; Boulant, J; D'Amato, M; Dapoigny, M; Mathieu, S1
Herberg, L; Klonowski-Stumpe, H; Meereis-Schwanke, K; Niederau, C2
Arai, I; Hirai, Y; Ida, Y; Komatsu, Y; Kuroiwa, Y; Sasaki, K; Shingu, K; Taguchi, S; Yamamoto, T; Yamaura, H1
Fujii, M; Kasai, H; Kimura, K; Ninomiya, K; Saeki, M; Saito, T; Wakatsuki, K1
Boesiger, P; Borovicka, J; Crelier, G; D'Amato, M; Fraser, R; Fried, M; Kreiss, C; Kunz, P; Schwizer, W1
Fujii, M; Kasai, H; Kimura, K; Masuda, T; Nakagawa, T; Saeki, M; Saito, T; Ukai, K; Wakatsuki, K1
de Boer, SY; Gielkens, HA; Lam, WF; Lamers, CB; Masclee, AA; Rovati, LC1
Kihara, Y; Nakano, S; Otsuki, M1
Fujii, M; Kasai, H; Kato, T; Kimura, K; Ninomiya, K; Saeki, M; Saito, T; Wakatsuki, K1
Chang, TM; Chey, WY; Coy, D; Lee, KY; Lee, ST; Li, P1
Biemond, I; Lamers, CB; Ledeboer, M; Masclee, AA1
Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A1
Bruley Des Varannes, S; D'Amato, M; Galmiche, JP; Leray, V; Rozé, C; Scarpignato, C; Zerbib, F1
Izumi, T1
Domschke, W; Hengst, K; Konturek, JW; Konturek, SJ; Sito, E; Stachura, J1
D'Amato, M; Dockray, GJ; Grazia Lucà, M; Jones, MN; McLaughlin, J; Thompson, DG1
Brzozowska, I; Brzozowski, T; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecién, S; Pajdo, R1
Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecień, S; Pajdo, R1
Beglinger, C; D'Amato, M; Degen, L; Drewe, J; Duebendorfer, R; Matzinger, D; Meuli, J; Rovati, L; Ruckstuhl, N1
Beglinger, C; Drewe, J; Gutzwiller, JP; Hildebrand, P; Ketterer, S; Krautheim, A1
Hayakawa, T; Ishiguro, H; Ito, O; Jin, C; Kitagawa, M; Nakajima, M; Naruse, S1
Domschke, W; Konturek, JW; Konturek, M; Konturek, SJ; Menzel, J; Stoll, R1
Ajjan, R; D'Amato, M; Hussain, FN; Moustafa, M; Riley, SA; Trudgill, NJ1
Akiyama, T; Fukumitsu, K; Jia, DM; Otani, M; Otsuki, M; Yamamoto, M; Yoshikawa, H1
Funayama, Y; Matsuno, S; Naito, H; Sasaki, I; Shibata, C; Takahashi, M1
Mostofsky, DI; Yehuda, S1
Feinle-Bisset, C; Horowitz, M; Little, TJ1
Chua, AS; Keeling, PW1
Duzman, R; Gonullu, D; Nihat Koksoy, F; Orhan Gurer, A; Sit, M; Yilmaz, N; Yucel, T1
Jia, D; Otsuki, M; Yamamoto, M1

Reviews

8 review(s) available for loxiglumide and cholecystokinin

ArticleYear
[Cholecystokinin and its antagonists: effects on digestive motility].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:10

    Topics: Benzodiazepinones; Brain; Cholecystokinin; Devazepide; Esophagus; Gallbladder; Gastric Emptying; Gastrointestinal Motility; Humans; Proglumide; Receptors, Cholecystokinin

1991
Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:4 Suppl 1

    Topics: Adult; Anti-Bacterial Agents; Cholecystokinin; Dietary Fats; Duodenal Ulcer; Eating; Gastric Acid; Gastrins; Helicobacter Infections; Helicobacter pylori; Hormones; Humans; Hydrogen-Ion Concentration; Male; Proglumide; Reference Values; Somatostatin

1994
Role of cholecystokinin in the control of gastric acid secretion and gastrin release in dogs and healthy and duodenal ulcer subjects.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:8

    Topics: Animals; Cholecystokinin; Dogs; Duodenal Ulcer; Gastric Acid; Gastrins; Humans; Proglumide; Receptors, Cholecystokinin; Somatostatin

1993
Effects of CCK on pancreatic function and morphology.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Animals; Cholecystokinin; Eating; Gallbladder; Humans; Islets of Langerhans; Pancreas; Proglumide

1994
Effect of cholecystokinin on gastric motility in humans.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Benzodiazepinones; Cholecystokinin; Colon; Devazepide; Digestive System; Digestive System Physiological Phenomena; Duodenum; Gastric Emptying; Gastrointestinal Motility; Humans; Ileum; Infusions, Intravenous; Proglumide; Receptors, Cholecystokinin; Sincalide

1994
Role of cholecystokinin in the regulation of satiation and satiety in humans.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Animals; Cholecystokinin; Humans; Infusions, Intravenous; Proglumide; Receptors, Cholecystokinin; Satiation; Satiety Response

1994
Role of cholecystokinin in appetite control and body weight regulation.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2005, Volume: 6, Issue:4

    Topics: Animals; Appetite; Body Weight; Cholecystokinin; Digestive System Physiological Phenomena; Energy Intake; Gastrointestinal Hormones; Hormone Antagonists; Humans; Obesity; Proglumide; Receptors, Cholecystokinin

2005
Cholecystokinin hyperresponsiveness in functional dyspepsia.
    World journal of gastroenterology, 2006, May-07, Volume: 12, Issue:17

    Topics: Atropine; Cholecystokinin; Dyspepsia; Efferent Pathways; Food Hypersensitivity; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Norepinephrine; Proglumide; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Stress, Psychological

2006

Trials

40 trial(s) available for loxiglumide and cholecystokinin

ArticleYear
Postprandial control of gallbladder contraction and exocrine pancreatic secretion in man.
    European journal of clinical investigation, 1992, Volume: 22, Issue:12

    Topics: Adult; Amylases; Atropine; Cholecystokinin; Eating; Gallbladder; Humans; Lipase; Male; Pancreas; Proglumide

1992
Effect of loxiglumide on basal and gastrin- and bombesin-stimulated gastric acid and serum gastrin levels.
    Gastroenterology, 1992, Volume: 103, Issue:4

    Topics: Adult; Bombesin; Cholecystokinin; Female; Gastric Acid; Gastrins; Humans; Male; Proglumide; Receptors, Cholecystokinin

1992
Dose-response effects of oral loxiglumide on postprandial gall-bladder emptying in man.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:11

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Double-Blind Method; Food; Gallbladder; Gallbladder Emptying; Humans; Male; Proglumide

1992
Role of circulating cholecystokinin in control of fat-induced inhibition of food intake in humans.
    Gastroenterology, 1992, Volume: 102, Issue:5

    Topics: Adult; Cholecystokinin; Dietary Fats; Eating; Energy Intake; Feeding Behavior; Humans; Male; Proglumide; Receptors, Cholecystokinin; Satiation

1992
Cholecystokinin's role in regulation of colonic motility in health and in irritable bowel syndrome.
    Gastroenterology, 1992, Volume: 102, Issue:6

    Topics: Adult; Ceruletide; Cholecystokinin; Colon; Colonic Diseases, Functional; Female; Gastrointestinal Motility; Humans; Male; Proglumide; Receptors, Cholecystokinin

1992
Cholecystokinin receptor antagonist loxiglumide modulates plasma levels of gastro-entero-pancreatic hormones in man. Feedback control of cholecystokinin and gastrin secretion.
    European journal of clinical investigation, 1991, Volume: 21, Issue:5

    Topics: Adult; Cholecystokinin; Eating; Feedback; Gastrins; Hormones; Humans; Male; Proglumide; Receptors, Cholecystokinin

1991
Physiological role of cholecystokinin on postprandial insulin secretion and gastric meal emptying in man. Studies with the cholecystokinin receptor antagonist loxiglumide.
    Diabetologia, 1991, Volume: 34, Issue:10

    Topics: Adult; C-Peptide; Cholecystokinin; Dietary Carbohydrates; Eating; Gastric Emptying; Glucose; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Middle Aged; Proglumide; Receptors, Cholecystokinin; Time Factors

1991
Effect of a cholecystokinin antagonist on meal-stimulated insulin and pancreatic polypeptide release in humans.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: Adult; Amino Acids; Cholecystokinin; Female; Food; Humans; Infusions, Intravenous; Insulin; Male; Pancreas; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1991
Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide.
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Adult; Cholecystokinin; Gastric Emptying; Humans; Lipase; Middle Aged; Pancreas; Pancreatic Polypeptide; Proglumide; Trypsin

1991
Cholecystokinin receptor antagonist loxiglumide: influence on bilio-pancreatic secretion and gastrointestinal hormones in man.
    Digestion, 1990, Volume: 46 Suppl 2

    Topics: Adult; Cholecystokinin; Gallbladder; Humans; Male; Muscle Contraction; Muscle, Smooth; Pancreas; Proglumide; Radioimmunoassay; Receptors, Cholecystokinin

1990
Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:1

    Topics: Administration, Oral; Adult; Cholecystokinin; Double-Blind Method; Female; Food; Gallbladder; Gastric Emptying; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Random Allocation

1990
Lack of effect of the specific cholecystokinin receptor antagonist loxiglumide on cholecystokinin clearance from plasma in man.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:6

    Topics: Adult; Cholecystokinin; Female; Glutamine; Half-Life; Humans; Male; Proglumide

1990
Role of cholecystokinin in regulation of gastrointestinal motor functions.
    Lancet (London, England), 1989, Jul-01, Volume: 2, Issue:8653

    Topics: 4-Aminobenzoic Acid; Administration, Oral; Adult; Cholecystokinin; Clinical Trials as Topic; Colon; Drug Evaluation; Eating; Gallbladder; Gastric Emptying; Gastrointestinal Transit; Homeostasis; Humans; Infusions, Intravenous; Intestine, Small; Male; para-Aminobenzoates; Proglumide; Random Allocation; Receptors, Cholecystokinin

1989
Effects of loxiglumide on gallbladder emptying in healthy volunteers.
    Gastroenterology, 1989, Volume: 97, Issue:5

    Topics: Adult; Ceruletide; Cholecystokinin; Food; Gallbladder; Humans; Infusions, Intravenous; Male; Proglumide; Receptors, Cholecystokinin

1989
Effects of somatostatin and loxiglumide on gallbladder motility.
    European journal of clinical pharmacology, 1995, Volume: 47, Issue:6

    Topics: Adult; Cholecystokinin; Double-Blind Method; Female; Gallbladder; Humans; Male; Proglumide; Somatostatin

1995
Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:4 Suppl 1

    Topics: Adult; Anti-Bacterial Agents; Cholecystokinin; Dietary Fats; Duodenal Ulcer; Eating; Gastric Acid; Gastrins; Helicobacter Infections; Helicobacter pylori; Hormones; Humans; Hydrogen-Ion Concentration; Male; Proglumide; Reference Values; Somatostatin

1994
Effect of endogenous cholecystokinin on postprandial gallbladder refilling. Ultrasonographic study in healthy subjects and in gallstone patients.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:1

    Topics: Adult; Cholecystokinin; Cholelithiasis; Double-Blind Method; Eating; Female; Gallbladder; Gallbladder Emptying; Humans; Male; Proglumide; Ultrasonography

1995
Loxiglumide inhibits cholecystokinin stimulated somatostatin secretion and simultaneously enhances gastric acid secretion in humans.
    Regulatory peptides, 1994, Oct-21, Volume: 53, Issue:3

    Topics: Adult; Cholecystokinin; Female; Gastric Acid; Gastric Mucosa; Humans; Infusions, Intravenous; Male; Proglumide; Receptors, Cholecystokinin; Somatostatin; Time Factors

1994
The effects of loxiglumide on food intake in normal weight volunteers.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1994, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Body Mass Index; Cholecystokinin; Cross-Over Studies; Double-Blind Method; Eating; Female; Humans; Hunger; Male; Proglumide; Satiation

1994
Role of cholecystokinin in the control of gastric emptying and secretory response to a fatty meal in normal subjects and duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:7

    Topics: Adult; Cholecystokinin; Dietary Fats; Duodenal Ulcer; Gastric Acid; Gastric Emptying; Gastrins; Humans; Hydrogen-Ion Concentration; Male; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin; Somatostatin

1994
Cholecystokinin is a physiological regulator of gastric acid secretion in man.
    European journal of clinical investigation, 1994, Volume: 24, Issue:6

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Eating; Gastric Acid; Gastric Mucosa; Gastrins; Homeostasis; Hormones; Humans; Male; Middle Aged; Proglumide; Sincalide; Somatostatin

1994
Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.
    Gastroenterology, 1994, Volume: 107, Issue:6

    Topics: Adult; Cholecystokinin; Eating; Gastric Acid; Gastric Mucosa; Gastrins; Humans; Male; Proglumide; Radioimmunoassay; Receptors, Cholecystokinin; Somatostatin; Stomach

1994
Effect of intravenous human gastrin-releasing peptide on food intake in humans.
    Gastroenterology, 1994, Volume: 106, Issue:5

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Double-Blind Method; Eating; Gastrin-Releasing Peptide; Gastrins; Humans; Infusions, Intravenous; Longitudinal Studies; Male; Peptides; Proglumide; Satiation; Time Factors

1994
Effect of a low dose of intraduodenal fat on satiety in humans: studies using the type A cholecystokinin receptor antagonist loxiglumide.
    Gut, 1994, Volume: 35, Issue:4

    Topics: Adult; Cholecystokinin; Duodenum; Eating; Fat Emulsions, Intravenous; Female; Humans; Hunger; Male; Proglumide; Receptors, Cholecystokinin; Satiation; Time Factors

1994
Effect of duodenal juice on bombesin-stimulated cholecystokinin release during loxiglumide administration in man.
    European journal of clinical investigation, 1993, Volume: 23, Issue:9

    Topics: Adult; Bombesin; Cholecystokinin; Female; Humans; Infusions, Intravenous; Male; Pancreatic Juice; Proglumide

1993
Bombesin reduces food intake after a preload in man by a cholecystokinin-independent mechanism.
    Clinical science (London, England : 1979), 1993, Volume: 85, Issue:3

    Topics: Adult; Bombesin; Cholecystokinin; Double-Blind Method; Eating; Energy Intake; Feeding Behavior; Female; Humans; Infusions, Intravenous; Proglumide

1993
Bombesin reduces food intake in lean man by a cholecystokinin-independent mechanism.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:6

    Topics: Adult; Bombesin; Cholecystokinin; Drug Combinations; Eating; Female; Humans; Male; Osmolar Concentration; Proglumide; Satiety Response

1993
Oral glucose ingestion stimulates cholecystokinin release in normal subjects and patients with non-insulin-dependent diabetes mellitus.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:2

    Topics: Administration, Oral; Adult; Atropine; Blood Glucose; Case-Control Studies; Cholecystokinin; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose; Hormone Antagonists; Humans; Insulin; Male; Middle Aged; Proglumide; Radioimmunoassay; Receptors, Cholecystokinin

1996
Eradication of Helicobacter pylori and gastrin-somatostatin link in duodenal ulcer patients.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:1

    Topics: Adult; Cholecystokinin; Duodenal Ulcer; Gastric Acid; Gastric Mucosa; Gastrins; Helicobacter Infections; Helicobacter pylori; Hormone Antagonists; Humans; Male; Proglumide; Somatostatin

1996
Intestinal phase of human antro-pyloro-duodenal motility: cholinergic and CCK-mediated regulation.
    European journal of clinical investigation, 1996, Volume: 26, Issue:7

    Topics: Acetylcholine; Adult; Atropine; Cholecystokinin; Duodenum; Gastrins; Gastrointestinal Motility; Hormone Antagonists; Humans; Male; Muscarinic Antagonists; Pancreatic Polypeptide; Proglumide; Pyloric Antrum; Pylorus; Receptor, Cholecystokinin A; Receptors, Cholecystokinin

1996
Physiological control of cholecystokinin release and pancreatic enzyme secretion by intraduodenal bile acids.
    Gut, 1996, Volume: 39, Issue:5

    Topics: Adult; Bile Acids and Salts; Bilirubin; Cholecystokinin; Duodenum; Hormone Antagonists; Humans; Intestinal Secretions; Male; Pancreas; Pancreatic Polypeptide; Perfusion; Proglumide; Receptors, Cholecystokinin

1996
Cholecystokinin in transient lower oesophageal sphincter relaxation due to gastric distension in humans.
    Gut, 1997, Volume: 40, Issue:5

    Topics: Adult; Cholecystokinin; Double-Blind Method; Esophagogastric Junction; Female; Gastroesophageal Reflux; Hormone Antagonists; Humans; Male; Manometry; Pressure; Proglumide; Receptors, Cholecystokinin; Stomach Diseases

1997
Role of cholecystokinin in the regulation of liquid gastric emptying and gastric motility in humans: studies with the CCK antagonist loxiglumide.
    Gut, 1997, Volume: 41, Issue:4

    Topics: Adult; Cholecystokinin; Female; Gastric Emptying; Gastrointestinal Motility; Hormone Antagonists; Humans; Magnetic Resonance Imaging; Male; Proglumide; Receptors, Cholecystokinin; Single-Blind Method; Stomach

1997
The role of cholecystokinin and the cholinergic system in intravenous amino acid-induced gallbladder emptying.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:12

    Topics: Adult; Amino Acids; Atropine; Cholecystokinin; Cholinergic Fibers; Gallbladder; Hormone Antagonists; Humans; Injections, Intravenous; Male; Muscarinic Antagonists; Proglumide; Ultrasonography

1997
Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Adult; Cholecystokinin; Duodenum; Eating; Enteral Nutrition; Esophagogastric Junction; Fasting; Female; Gastric Fundus; Hormone Antagonists; Humans; Male; Manometry; Muscle Relaxation; Muscle Tonus; Proglumide; Receptor, Cholecystokinin A; Receptors, Cholecystokinin

1998
Physiological role of cholecystokinin in gastroprotection in humans.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:12

    Topics: Adult; Cholecystokinin; Double-Blind Method; Duodenum; Ethanol; Gastric Mucosa; Gastroscopy; Hormone Antagonists; Humans; Injections, Intravenous; Male; Oleic Acid; Proglumide; Sincalide; Somatostatin; Stomach

1998
The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans.
    Gut, 2000, Volume: 46, Issue:5

    Topics: Adult; Cholecystokinin; Cross-Over Studies; Double-Blind Method; Duodenum; Eating; Energy Intake; Fatty Acids; Hormone Antagonists; Humans; Hunger; Male; Proglumide; Receptors, Cholecystokinin

2000
Interaction between CCK and a preload on reduction of food intake is mediated by CCK-A receptors in humans.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:1

    Topics: Adult; Cholecystokinin; Cross-Over Studies; Double-Blind Method; Eating; Energy Intake; Humans; Hunger; Infusions, Intravenous; Male; Proglumide; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Satiety Response; Sincalide

2000
Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Cholecystokinin; Duodenal Ulcer; Follow-Up Studies; Gastric Emptying; Gastric Mucosa; Gastrins; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Hormone Antagonists; Humans; Injections, Intravenous; Male; Postprandial Period; Probability; Proglumide; Reference Values; Sensitivity and Specificity; Somatostatin; Sucralfate; Treatment Outcome

2001
The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with reflux disease.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: Adult; Aged; Cholecystokinin; Cross-Over Studies; Double-Blind Method; Esophagogastric Junction; Female; Gastroesophageal Reflux; Hormone Antagonists; Humans; Male; Middle Aged; Postprandial Period; Proglumide

2001

Other Studies

111 other study(ies) available for loxiglumide and cholecystokinin

ArticleYear
Role of endogenously released cholecystokinin in determining postprandial insulin levels in man: effects of loxiglumide, a specific cholecystokinin receptor antagonist.
    Digestion, 1992, Volume: 53, Issue:3-4

    Topics: Adult; Blood Glucose; Cholecystokinin; Gallbladder Emptying; Gastric Inhibitory Polypeptide; Humans; Insulin; Male; Pancreas; Proglumide; Receptors, Cholecystokinin

1992
Direct contractile effect of motilin on isolated smooth muscle cells of guinea pig small intestine.
    Life sciences, 1992, Volume: 51, Issue:17

    Topics: Animals; Atropine; Calcium; Cholecystokinin; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Proglumide; Substance P

1992
[Effects of cholecystokinin and its antagonists on the GI tract. Potent inhibition of gastrointestinal motility by loxiglumide].
    Fortschritte der Medizin, 1992, Oct-10, Volume: 110, Issue:28

    Topics: Bile Acids and Salts; Cholecystokinin; Dose-Response Relationship, Drug; Gallbladder; Gastrointestinal Motility; Humans; Proglumide

1992
Effect of loxiglumide and atropine on erythromycin-induced reduction in gallbladder volume in human subjects.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:4

    Topics: Adult; Atropine; Cholecystokinin; Erythromycin; Female; Gallbladder; Humans; Male; Pancreatic Polypeptide; Proglumide; Pulse; Ultrasonography

1992
Role of cholecystokinin in mediating GRP-stimulated gastric, biliary and pancreatic functions in man.
    Regulatory peptides, 1992, Sep-22, Volume: 41, Issue:2

    Topics: Adult; Cholecystokinin; Gallbladder; Gastric Acid; Gastrin-Releasing Peptide; Gastrins; Gastrointestinal Hormones; Humans; Male; Pancreas; Peptides; Proglumide

1992
[Effects of UFT and loxiglumide (CR1505) on liver metastasis of human pancreatic cancer cell line, KP-1 N in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholecystokinin; Humans; Liver Neoplasms; Mice; Mice, Nude; Pancreatic Neoplasms; Proglumide; Tegafur; Tumor Cells, Cultured; Uracil

1992
Combined dose-ratio analysis of cholecystokinin receptor antagonists, devazepide, lorglumide and loxiglumide in the guinea-pig gall bladder.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Analysis of Variance; Animals; Benzodiazepinones; Binding, Competitive; Biological Assay; Cholecystokinin; Devazepide; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs; Muscle, Smooth; Pentagastrin; Proglumide; Receptors, Cholecystokinin; Sincalide

1992
[Effect of combined use of CR 1505 with UFT on tumor growth of transplanted pancreatic cancer in the Syrian golden hamster: preliminary report].
    Nihon Geka Gakkai zasshi, 1992, Volume: 93, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholecystokinin; Cricetinae; Drug Synergism; Mesocricetus; Neoplasm Transplantation; Pancreatic Neoplasms; Proglumide; Tegafur; Uracil

1992
Intestinal microcirculatory changes during fat absorption and the effect of cholecystokinin inhibitor.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: Animals; Blood Flow Velocity; Cholecystokinin; Dietary Fats; Erythrocytes; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lymph; Male; Microcirculation; Muscle, Smooth; Muscle, Smooth, Vascular; Oleic Acid; Oleic Acids; Proglumide; Rats; Rats, Inbred Strains

1992
Growth inhibition of human pancreatic cancer cells by cholecystokinin receptor antagonist in tissue culture and in nude mice.
    Gastroenterologia Japonica, 1992, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Animals; Ceruletide; Cholecystokinin; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Pancreatic Neoplasms; Proglumide; Tumor Cells, Cultured

1992
Effects of cholecystokinin receptor blockade on circulating concentrations of glucose, insulin, C-peptide, and pancreatic polypeptide after various meals in healthy human volunteers.
    Pancreas, 1992, Volume: 7, Issue:1

    Topics: Administration, Oral; Adult; Blood Glucose; C-Peptide; Cholecystokinin; Diet; Dose-Response Relationship, Drug; Glucose; Humans; Infusions, Intravenous; Insulin; Male; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1992
Determination of plasma cholecystokinin (CCK) concentrations by bioassay and radioimmunoassay in man. A critical evaluation.
    Regulatory peptides, 1992, Feb-18, Volume: 37, Issue:3

    Topics: Adult; Animals; Biological Assay; Cholecystokinin; Eating; Evaluation Studies as Topic; Humans; Lipase; Male; Pancreas; Proglumide; Radioimmunoassay; Rats; Rats, Inbred Strains

1992
Inhibitory effects of the cholecystokinin antagonist loxiglumide on pancreatic exocrine secretion and pancreatic growth in conscious rats.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1992, Volume: 11, Issue:2

    Topics: Animals; Cholecystokinin; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Inbred Strains

1992
Cholecystokinin contracts isolated human and monkey iris sphincters; a study with CCK receptor antagonists.
    European journal of pharmacology, 1992, Feb-11, Volume: 211, Issue:2

    Topics: Aged; Aged, 80 and over; Animals; Cholecystokinin; Female; Humans; In Vitro Techniques; Iris; Macaca fascicularis; Male; Middle Aged; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Sincalide

1992
Cephalic stimulation of gastrointestinal secretory and motor responses in humans.
    Gastroenterology, 1992, Volume: 103, Issue:2

    Topics: Adult; Atropine; Brain; Cholecystokinin; Eating; Gastric Acid; Gastrins; Gastrointestinal Motility; Humans; Male; Pancreas; Pancreatic Polypeptide; Proglumide

1992
A physiological role for cholecystokinin as a regulator of gastrin secretion.
    Gastroenterology, 1992, Volume: 103, Issue:2

    Topics: Adult; Cholecystokinin; Food; Gastrin-Releasing Peptide; Gastrins; Humans; Male; Peptides; Proglumide

1992
Interaction of the cholinergic system and cholecystokinin in the regulation of endogenous and exogenous stimulation of pancreatic secretion in humans.
    Gastroenterology, 1991, Volume: 100, Issue:2

    Topics: Adult; Amylases; Atropine; Ceruletide; Cholecystokinin; Chymotrypsin; Food; Humans; Lipase; Male; Pancreas; Parasympathetic Nervous System; Proglumide; Trypsin

1991
Effect of the specific cholecystokinin-receptor antagonist loxiglumide on bombesin stimulated pancreatic enzyme secretion in man.
    Regulatory peptides, 1991, Feb-26, Volume: 32, Issue:3

    Topics: Adult; Amylases; Bilirubin; Bombesin; Cholecystokinin; Duodenum; Female; Humans; Male; Pancreas; Proglumide; Receptors, Cholecystokinin

1991
Neuroendocrine regulation of growth hormone secretion in sheep. IV. Central and peripheral cholecystokinin.
    Domestic animal endocrinology, 1991, Volume: 8, Issue:4

    Topics: Animals; Cholecystokinin; Growth Hormone; Immune Sera; Injections, Intravenous; Injections, Intraventricular; Male; Neurosecretory Systems; Proglumide; Sheep

1991
[Effects of CR1505, a CCK antagonist, on pancreatic growth in hamsters].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1991, Volume: 88, Issue:4

    Topics: Animals; Cholecystokinin; Cricetinae; Dose-Response Relationship, Drug; Male; Mesocricetus; Pancreas; Proglumide

1991
CCK receptor antagonist loxiglumide alters uptake of CCK in perfused liver and pancreatic acini of the rat.
    Digestion, 1991, Volume: 48, Issue:2

    Topics: Animals; Ceruletide; Cholecystokinin; Liver; Male; Pancreas; Perfusion; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin

1991
Role of CCK in regulation of pancreaticobiliary functions and GI motility in humans: effects of loxiglumide.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Adult; Bilirubin; Cholecystokinin; Eating; Feces; Gallbladder; Gastrointestinal Motility; Humans; Lipase; Lipid Metabolism; Male; Muscle Contraction; Muscle, Smooth; Pancreas; Pancreatic Juice; Proglumide; Reference Values; Trypsin

1991
Effects of CCK receptor blockade on intestinal motor activity in conscious dogs.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Animals; Ceruletide; Cholecystokinin; Digestion; Dogs; Eating; Female; Gastrointestinal Motility; Male; Muscle Contraction; Myoelectric Complex, Migrating; Neostigmine; Proglumide; Receptors, Cholecystokinin

1991
Studies of three non-peptide cholecystokinin antagonists (devazepide, lorglumide and loxiglumide) in human isolated alimentary muscle and guinea-pig ileum.
    British journal of pharmacology, 1991, Volume: 102, Issue:2

    Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Digestive System; Digestive System Physiological Phenomena; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Sincalide

1991
Effects of cholecystokinin-receptor blockade on pancreatic and biliary function in healthy volunteers.
    Gastroenterology, 1991, Volume: 100, Issue:6

    Topics: Adult; Bilirubin; Cholecystokinin; Female; Gallbladder; Humans; Intestinal Absorption; Male; Pancreas; Pancreatic Juice; Proglumide; Receptors, Cholecystokinin

1991
[Therapeutic perspectives in the irritable bowel syndrome].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:5 ( Pt 2)

    Topics: Abdominal Pain; Antidiarrheals; Benzodiazepines; Cholecystokinin; Colonic Diseases, Functional; Constipation; Diarrhea; Female; Humans; Male; Proglumide

1990
Effect of loxiglumide, a cholecystokinin antagonist, on pancreatic polypeptide release in humans.
    Gastroenterology, 1990, Volume: 99, Issue:6

    Topics: Adult; Cholecystokinin; Duodenum; Eating; Female; Humans; Intubation, Gastrointestinal; Male; Pancreatic Polypeptide; Perfusion; Proglumide

1990
Cholecystokinin is a regulator of intestinal phase-stimulated PP release.
    Regulatory peptides, 1990, Sep-10, Volume: 30, Issue:2

    Topics: Adult; Atropine; Ceruletide; Cholecystokinin; Humans; Infusions, Intravenous; Intestinal Mucosa; Male; Pancreatic Polypeptide; Proglumide

1990
Effects of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and biliary responses in man.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:3

    Topics: Adult; Bile Acids and Salts; Cholecystokinin; Food; Glutamine; Humans; Intestines; Male; Pancreas; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1990
Effect of loxiglumide on gallbladder contractile response to cerulein and food in humans.
    Gastroenterology, 1990, Volume: 98, Issue:5 Pt 1

    Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Reference Values; Time Factors

1990
Mechanism of inhibitory action of peptide YY on cholecystokinin-induced contractions of isolated dog ileum.
    Regulatory peptides, 1990, Feb-04, Volume: 27, Issue:2

    Topics: Animals; Cholecystokinin; Dogs; Female; Gallbladder; Glutamine; Ileum; Isometric Contraction; Male; Muscle Contraction; Peptide YY; Peptides; Proglumide; Sincalide

1990
Cholecystokinin in the inhibition of gastric secretion and gastric emptying in humans.
    Digestion, 1990, Volume: 45, Issue:1

    Topics: Adult; Cholecystokinin; Dietary Fats; Gastric Acid; Gastric Emptying; Gastrins; Humans; Male; Pancreatic Polypeptide; Peptones; Proglumide; Receptors, Cholecystokinin

1990
Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Disease Models, Animal; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Taurocholic Acid

1990
Effect of loxiglumide (CR-1505) on bombesin- and meal-stimulated plasma cholecystokinin in man.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:4

    Topics: Adult; Bombesin; Cholecystokinin; Female; Food; Glutamine; Humans; Male; Proglumide; Receptors, Cholecystokinin

1990
Fasting prevents acute pancreatitis induced by cerulein in rats.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:7

    Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Fasting; Male; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Secretin

1990
Receptor type for cholecystokinin on isolated intestinal muscle cells of the guinea pig.
    Regulatory peptides, 1990, May-21, Volume: 28, Issue:3

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gallbladder; Gastrins; Guinea Pigs; Hormones; Intestinal Mucosa; Intestines; Muscle, Smooth; Pancreas; Pentagastrin; Proglumide; Receptors, Cholecystokinin

1990
Comparison of loxiglumide, a cholecystokinin receptor antagonist, and atropine on hormonal and meal-stimulated pancreatic secretion in man.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:7

    Topics: Adult; Atropine; Bicarbonates; Cholecystokinin; Duodenum; Eating; Food, Formulated; Glutamine; Humans; Infusions, Intravenous; Pancreas; Proglumide; Receptors, Cholecystokinin; Secretin; Secretory Rate

1990
Comparative effects of CCK receptor antagonists on rat pancreatic secretion in vivo.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Amylases; Animals; Benzodiazepinones; Ceruletide; Cholecystokinin; Chymotrypsinogen; Devazepide; Dose-Response Relationship, Drug; Male; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Secretin

1989
Loxiglumide. A new proglumide analog with potent cholecystokinin antagonistic activity in the rat pancreas.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:6

    Topics: Amylases; Animals; Binding, Competitive; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide

1989
[Inhibitory effect of a new proglumide derivative, loxiglumide, on CCK action in isolated rat pancreatic acini].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; In Vitro Techniques; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1989
Treatment of biliary colic with loxiglumide.
    Lancet (London, England), 1989, Jul-15, Volume: 2, Issue:8655

    Topics: Biliary Tract Diseases; Cholecystokinin; Colic; Female; Glutamine; Humans; Male; Proglumide; Time Factors

1989
Pharmacokinetics and tolerance of repeated oral doses of loxiglumide.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:11

    Topics: Adult; Biotransformation; Cholecystokinin; Female; Glutamine; Humans; Male; Patient Compliance; Proglumide

1989
[Effect of CCK on the large intestine].
    Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:5

    Topics: Animals; Cholecystokinin; Gastrointestinal Motility; Glutamine; Intestine, Large; Male; Muscle Contraction; Muscle, Smooth; Proglumide; Rats; Rats, Inbred Strains

1989
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Adult; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Feedback; Gabexate; Glutamine; Guanidines; Humans; Male; Pancreas; Peptide Hydrolases; Proglumide; Protease Inhibitors; Pulse; Reference Values

1989
CCK receptor antagonism by loxiglumide and gall bladder contractions in response to cholecystokinin, sham feeding and ordinary feeding in man.
    Gut, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Cholecystokinin; Food; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Sincalide

1989
The effect of loxiglumide (CR-1505) on basal and bombesin-stimulated gallbladder volume in man.
    European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2

    Topics: Adult; Bombesin; Cholecystokinin; Female; Gallbladder; Humans; Male; Muscle Contraction; Muscle, Smooth; Proglumide; Time Factors

1989
Effect of CCK antagonists CR 1409 and CR 1505 on rat pancreatic exocrine secretion in vivo.
    Pancreas, 1989, Volume: 4, Issue:6

    Topics: Animals; Caseins; Cholecystokinin; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1989
Pharmacokinetics of loxiglumide after single intravenous or oral doses in man.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Cholecystokinin; Chromatography, High Pressure Liquid; Glutamine; Humans; Infusions, Intravenous; Injections, Intravenous; Proglumide

1988
Anticholecystokinin activities of loxiglumide.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:10

    Topics: Anesthesia; Animals; Ceruletide; Cholecystokinin; Dogs; Female; Gallbladder; Gastrointestinal Motility; Glutamine; Guinea Pigs; In Vitro Techniques; Male; Mice; Pancreas; Proglumide; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1987
Biological effects of a proglumide derivative as cholecystokinin antagonist in conscious dogs.
    Regulatory peptides, 1987, Aug-17, Volume: 18, Issue:3-4

    Topics: Animals; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Glutamine; Infusions, Intravenous; Pancreatic Juice; Pancreatic Polypeptide; Pentagastrin; Proglumide; Sincalide

1987
Pharmacological characterisation of a new potent and specific nonpolypeptidic cholecystokinin antagonist.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:6

    Topics: Animals; Cerebral Cortex; Cholecystokinin; Female; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Species Specificity

1987
Cholecystokinin in the control of gastric acid secretion and gastrin release in response to a meal at low and high pH in healthy subjects and duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:8

    Topics: Adult; Case-Control Studies; Cholecystokinin; Duodenal Ulcer; Food; Gastric Acid; Gastrins; Hormone Antagonists; Humans; Hydrogen-Ion Concentration; Male; Premedication; Proglumide; Receptors, Cholecystokinin; Somatostatin; Time Factors

1995
Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on postprandial gastrin release in duodenal ulcer patients.
    Gut, 1995, Volume: 37, Issue:4

    Topics: Adult; Cholecystokinin; Duodenal Ulcer; Eating; Gastric Acid; Gastrins; Helicobacter Infections; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Male; Monitoring, Physiologic; Proglumide; Somatostatin

1995
Loxiglumide, L-364,718 and L-365,260 prevent the inhibition of spontaneous acetylcholine release from the frontal cerebral cortex of freely moving rat peripherally administered with cholecystokinin-8S.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Acetylcholine; Animals; Benzodiazepinones; Cerebral Cortex; Cholecystokinin; Devazepide; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Phenylurea Compounds; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin

1995
Cholecystokinin in the hormonal stimulation of amino acid uptake and pancreatic enzyme secretion.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Adult; Amino Acids; Amylases; Bicarbonates; Ceruletide; Cholecystokinin; Gallbladder; Humans; Male; Pancreas; Pancreatic Polypeptide; Proglumide; Secretin

1994
Exogenous and endogenous cholecystokinin protects gastric mucosa against the damage caused by ethanol in rats.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspirin; Cholecystokinin; Dose-Response Relationship, Drug; Duodenum; Ethanol; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Regional Blood Flow; Stomach Ulcer

1995
Cholinergic stimulatory effect of intragastric administration of a prostaglandin E2 analogue on pancreatic exocrine secretion in conscious rats.
    Pancreas, 1995, Volume: 10, Issue:4

    Topics: Amylases; Animals; Antibodies; Atropine; Cholecystokinin; Cyclic AMP; Enprostil; Injections, Intravenous; Kinetics; Male; Pancreas; Proglumide; Rats; Rats, Wistar; Secretin; Stomach; Vagotomy

1995
Involvement of endogenous cholecystokinin in the development of acute pancreatitis induced by closed duodenal loop.
    Pancreas, 1993, Volume: 8, Issue:1

    Topics: Acute Disease; Amylases; Animals; Cholecystokinin; Disease Models, Animal; Duodenum; Lipase; Male; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Wistar

1993
Effect of intrinsic CCK and CCK antagonist on pancreatic growth and pancreatic enzyme secretion in pancreaticobiliary diversion rats.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:4

    Topics: Amylases; Animals; Biliary Tract Surgical Procedures; Cholecystokinin; Hypertrophy; Lipase; Male; Pancreas; Proglumide; Rats; Rats, Wistar; Secretin; Time Factors; Trypsinogen

1993
A cholecystokinin receptor antagonist, loxiglumide, stimulates biliary secretion in conscious rats.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Analysis of Variance; Animals; Benzodiazepinones; Bile; Bile Acids and Salts; Bile Ducts; Bilirubin; Cholecystokinin; Devazepide; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin

1994
Regulation of pancreatic polypeptide release is mediated through M3 muscarinic receptors.
    Digestion, 1994, Volume: 55, Issue:6

    Topics: Animals; Atropine; Cholecystokinin; Dogs; Female; Gastric Acid; Male; Pancreatic Juice; Pancreatic Polypeptide; Parasympatholytics; Piperidines; Pirenzepine; Proglumide; Receptors, Muscarinic; Vagus Nerve

1994
Negative feedback regulation of pancreatic exocrine secretion in guinea pigs.
    Pancreas, 1995, Volume: 10, Issue:2

    Topics: Animals; Atropine; Cholecystokinin; Chymotrypsin; Feedback; Guinea Pigs; Male; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Juice; Proglumide; Radioimmunoassay; Secretin; Trypsin

1995
Lack of effect of cholecystokinin receptor antagonist (CR1505) on recovery of experimental pancreatitis after pancreatic duct occlusion in rats.
    Pancreas, 1994, Volume: 9, Issue:5

    Topics: Animals; Body Weight; Cholecystokinin; Duodenum; Eating; Intestinal Mucosa; Ligation; Male; Organ Size; Pancreatic Ducts; Pancreatitis; Proglumide; Proteins; Rats; Rats, Wistar; Receptors, Cholecystokinin; Regeneration

1994
PD 135158, a CCKB/gastrin receptor antagonist, stimulates rat pancreatic enzyme secretion as a CCKA receptor agonist.
    European journal of pharmacology, 1993, Sep-21, Volume: 242, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Cholecystokinin; Drug Interactions; Indoles; Lipase; Meglumine; Pancreas; Proglumide; Rats; Sincalide

1993
Cholecystokinin in the control of gastric acid secretion in humans.
    Journal of clinical gastroenterology, 1993, Volume: 17 Suppl 1

    Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastrin-Releasing Peptide; Gastrins; Humans; Male; Peptides; Proglumide; Receptors, Cholecystokinin; Somatostatin

1993
Effect of intraduodenal infusion of tocamphyl on pancreatic exocrine secretion and gastrointestinal hormone release in rats.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1994, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Atropine; Bile; Camphor; Cholagogues and Choleretics; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Ethanolamines; Gastrointestinal Hormones; Male; Pancreatic Juice; Proglumide; Radioimmunoassay; Rats; Rats, Wistar; Secretin; Sincalide

1994
Effect of protein derivatives on pancreatic secretion and release of secretin and CCK in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 1

    Topics: Amino Acids; Animals; Cholecystokinin; Immune Sera; Male; Oligopeptides; Pancreas; Proglumide; Proteins; Rats; Rats, Wistar; Receptors, Cholecystokinin; Secretin; Solutions

1994
Physiological role of cholecystokinin on gastric emptying and acid output in dogs.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:11

    Topics: Animals; Cholecystokinin; Dogs; Gastric Acid; Gastric Emptying; Gastrins; Proglumide; Somatostatin

1994
Effect of digested protein on pancreatic exocrine secretion and gut hormone release in the dog.
    Pancreas, 1994, Volume: 9, Issue:1

    Topics: Animals; Bicarbonates; Cholecystokinin; Dogs; Female; Kinetics; Liver; Male; Pancreas; Pancreatic Juice; Proglumide; Proteins; Receptors, Cholecystokinin; Secretin

1994
Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladder.
    Neuropeptides, 1993, Volume: 25, Issue:5

    Topics: Acetylcholine; Animals; Cholecystokinin; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Proglumide; Tritium

1993
Influence of fatty acid absorption on bidirectional release of immunoglobulin A into intestinal lumen and intestinal lymph in rats.
    Immunology letters, 1993, Volume: 38, Issue:3

    Topics: Animals; Cholecystokinin; Fatty Acids; Immunoglobulin A, Secretory; Intestinal Absorption; Intestines; Lymph; Male; Micelles; Poloxalene; Proglumide; Rats; Rats, Wistar

1993
Endogenous CCK in the control of gastric secretory response to meal in normal subjects and duodenal ulcer patients.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Adult; Cholecystokinin; Duodenal Ulcer; Eating; Gastric Acid; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Proglumide; Receptors, Cholecystokinin; Reference Values

1994
Loxiglumide (CR1505), a cholecystokinin antagonist, specifically inhibits the growth of human pancreatic cancer lines xenografted into nude mice.
    Cancer, 1993, Dec-15, Volume: 72, Issue:12

    Topics: Animals; Cell Division; Chloroquine; Cholecystokinin; DNA; Esters; Gabexate; Guanidines; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organ Culture Techniques; Pancreatic Neoplasms; Proglumide; Sincalide; Transplantation, Heterologous

1993
Inhibitory effects of a cholecystokinin antagonist, loxiglumide (CR-1505), on the growth of freshly separated and xenografted human pancreatic cancer.
    Journal of surgical oncology, 1993, Volume: 53, Issue:1

    Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cholecystokinin; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Proglumide; RNA, Neoplasm; Transplantation, Heterologous; Tumor Cells, Cultured

1993
Effect of cholestyramine and cholecystokinin receptor antagonist CR1505 (loxiglumide) on lower esophageal sphincter pressure in man.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:10

    Topics: Adult; Aged; Cholecystokinin; Cholestyramine Resin; Esophagogastric Junction; Female; Humans; Male; Middle Aged; Pressure; Proglumide; Receptors, Cholecystokinin

1993
Cholecystokinin does not delay gastric emptying of regular meals in healthy humans.
    Hepato-gastroenterology, 1993, Volume: 40, Issue:4

    Topics: Cholecystokinin; Dose-Response Relationship, Drug; Gastric Emptying; Humans; Proglumide

1993
Inhibitory effect of intraduodenal infusion of loxiglumide on pancreatic exocrine secretion.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:1

    Topics: Animals; Cholecystokinin; Dogs; Duodenum; Female; Infusions, Intravenous; Intubation, Gastrointestinal; Male; Pancreas; Proglumide; Proteins

1993
Cholecystokinin in the control of gastric acid secretion in man.
    Gut, 1993, Volume: 34, Issue:3

    Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Food; Gastric Acid; Gastrin-Releasing Peptide; Gastrins; Humans; Hydrogen-Ion Concentration; Male; Pentagastrin; Peptides; Proglumide; Receptors, Cholecystokinin; Secretory Rate

1993
Duration and potency of anticholecystokinin action of subcutaneous and oral loxiglumide on cerulein-stimulated pancreatic exocrine secretion.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1993, Volume: 13, Issue:2

    Topics: Administration, Oral; Animals; Ceruletide; Cholecystokinin; Injections, Subcutaneous; Male; Pancreas; Proglumide; Rats; Rats, Wistar; Time Factors

1993
Cholecystokinin in the regulation of gastric acid and endocrine pancreatic secretion in humans.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:5

    Topics: Adult; Cholecystokinin; Food; Gastric Acid; Gastrins; Humans; Hydrogen-Ion Concentration; Male; Monitoring, Physiologic; Pancreas; Pancreatic Hormones; Proglumide; Radioimmunoassay

1993
[Effect of combined use of CR1505 with UFT for the tumor growth of the subcutaneously transplanted pancreatic cancer in the Syrian golden hamsters].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1993, Volume: 90, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholecystokinin; Cricetinae; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Proglumide; Tegafur; Uracil

1993
Effects of intraduodenal administration of a low dose of cholecystokinin (CCK) antagonist (CR-1505) on plasma CCK concentration, intestinal CCK content, and levels of CCK mRNA.
    Journal of gastroenterology, 1995, Volume: 30, Issue:5

    Topics: Animals; Base Sequence; Body Weight; Cholecystokinin; Drug Administration Routes; Gene Expression; Hormone Antagonists; Intestinal Mucosa; Male; Molecular Sequence Data; Pancreas; Proglumide; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trypsin

1995
Regulation of gene expression of pancreatic secretory trypsin inhibitor-61 and -56 by bile and pancreatic juice in rats.
    Pancreas, 1995, Volume: 11, Issue:3

    Topics: Animals; Base Sequence; Bile; Biliopancreatic Diversion; Ceruletide; Cholecystokinin; Gastrointestinal Agents; Gene Expression; Hormone Antagonists; Infusions, Intravenous; Male; Molecular Sequence Data; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Wistar; RNA, Messenger; Sincalide; Trypsin Inhibitor, Kazal Pancreatic

1995
Cholecystokinin-GABA interactions in rat striatum.
    Neuropeptides, 1995, Volume: 29, Issue:5

    Topics: Animals; Calcium; Cholecystokinin; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Hormone Antagonists; Indoles; Male; Meglumine; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin; Tritium

1995
Luminal cholecystokinin and gastrin cause gallbladder contraction.
    The Journal of surgical research, 1996, Volume: 62, Issue:2

    Topics: Animals; Bile; Cholecystokinin; Female; Gallbladder; Gastrins; Guinea Pigs; Hormone Antagonists; In Vitro Techniques; Muscle Contraction; Pentagastrin; Proglumide; Receptors, Cholecystokinin; Sincalide

1996
Effects of cholecystokinin and carbachol on membrane fluidity in pancreatic acini.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:7

    Topics: Animals; Bombesin; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Hormone Antagonists; L-Lactate Dehydrogenase; Male; Membrane Fluidity; Pancreas; Pancreatitis; Phosphatidylcholines; Proglumide; Rats; Rats, Wistar; Secretin; Sincalide

1996
Role of endogenous platelet-activating factor in the regulation of pancreatic blood flow during caerulein stimulation.
    Journal of gastroenterology, 1996, Volume: 31, Issue:3

    Topics: Animals; Ceruletide; Cholecystokinin; Gastrointestinal Agents; Hormone Antagonists; Laser-Doppler Flowmetry; Male; Pancreas; Platelet Activating Factor; Proglumide; Pyridinium Compounds; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Time Factors

1996
Comparison of the effects of two cholecystokinin-receptor antagonists, loxiglumide and L-364,718, on the pancreatic secretory response to intraduodenal tryptophan in dogs.
    Scandinavian journal of gastroenterology, 1996, Volume: 31, Issue:7

    Topics: Animals; Benzodiazepinones; Bicarbonates; Cholecystokinin; Devazepide; Dogs; Duodenum; Female; Male; Pancreas; Perfusion; Proglumide; Receptors, Cholecystokinin; Secretin; Sincalide; Tryptophan

1996
Role of endogenous cholecystokinin in the regeneration of pancreatic tissue after acute hemorrhagic pancreatitis in rats.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1996, Volume: 87, Issue:1

    Topics: Acute Disease; Animals; Cholecystokinin; Hemorrhage; Male; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Regeneration

1996
Effect of a cholecystokinin receptor antagonist (loxiglumide) on gallbladder contractile function in guinea pigs.
    Journal of gastroenterology, 1996, Volume: 31, Issue:4

    Topics: Animals; Ceruletide; Cholecystokinin; Depression, Chemical; Gallbladder; Gallbladder Emptying; Gastrointestinal Agents; Guinea Pigs; Hormone Antagonists; Male; Proglumide; Receptors, Cholecystokinin

1996
Both free and complexed trypsin inhibitors stimulate pancreatic secretion and change duodenal enzyme levels.
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Duodenum; Enteral Nutrition; Epithelial Cells; Epithelium; Hormone Antagonists; Intestine, Small; Pancreas; Peptides; Plant Proteins; Proglumide; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Stimulation, Chemical; Trypsin Inhibitors

1997
CCK-resistance in Zucker obese versus lean rats.
    Regulatory peptides, 1997, Jun-18, Volume: 70, Issue:2-3

    Topics: Amylases; Animals; Capsaicin; Cholecystokinin; Eating; Female; Injections, Subcutaneous; Male; Obesity; Proglumide; Rats; Rats, Zucker; Receptors, Cholecystokinin

1997
Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats.
    Planta medica, 1997, Volume: 63, Issue:5

    Topics: Animals; Atropine; Cholecystokinin; Duodenum; Esters; Gabexate; Glycyrrhizic Acid; Guanidines; Japan; Male; Pancreas; Pancreatic Juice; Plant Extracts; Plant Roots; Plants, Medicinal; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Saponins; Triterpenes; Trypsin; Trypsin Inhibitors

1997
Cholecystokinin antagonistic activities of loxiglumide.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:10

    Topics: Animals; Cholecystokinin; Gallbladder; Gallbladder Emptying; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Guinea Pigs; Hormone Antagonists; In Vitro Techniques; Injections, Intravenous; Male; Mice; Mice, Inbred ICR; Proglumide; Rabbits; Rats; Rats, Sprague-Dawley

1997
General pharmacological profile of the novel cholecystokinin-A antagonist loxiglumide.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:12

    Topics: Animals; Autonomic Nervous System; Behavior, Animal; Central Nervous System; Cholecystokinin; Digestive System; Dogs; Female; Guinea Pigs; Hemodynamics; Hormone Antagonists; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Proglumide; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Respiration

1997
Long-term effects of CCK-agonist and -antagonist on food intake and body weight in Zucker lean and obese rats.
    Peptides, 1998, Volume: 19, Issue:2

    Topics: Animals; Body Weight; Ceruletide; Cholecystokinin; Drug Resistance; Eating; Female; Male; Obesity; Organ Size; Pancreas; Proglumide; Rats; Rats, Zucker; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Satiety Response

1998
CCK administration after CCK receptor blockade accelerates recovery from cerulein-induced acute pancreatitis in rats.
    Pancreas, 1998, Volume: 16, Issue:2

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Cholecystokinin; DNA; Hormone Antagonists; Lipase; Male; Organ Size; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Regeneration; Sincalide; Trypsin

1998
Effects of loxiglumide on pancreatic exocrine secretion stimulated by cholecystokinin-8 in conscious dogs.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Dogs; Female; Hormone Antagonists; In Vitro Techniques; Pancreas; Pancreatic Juice; Proglumide; Proteins; Receptors, Cholecystokinin; Trypsin

1998
Pituitary adenylate cyclase-activating peptide stimulates rat pancreatic secretion via secretin and cholecystokinin releases.
    Gastroenterology, 1998, Volume: 114, Issue:5

    Topics: Animals; Cholecystokinin; Hormone Antagonists; Immune Sera; Male; Neuropeptides; Pancreas; Pituitary Adenylate Cyclase-Activating Polypeptide; Proglumide; Rats; Rats, Sprague-Dawley; Secretin

1998
Effect of medium- and long-chain triglycerides on lower esophageal sphincter pressure: role of CCK.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Adult; Cholecystokinin; Dietary Fats; Duodenum; Esophagogastric Junction; Female; Gallbladder; Hormone Antagonists; Humans; Infusions, Intravenous; Kinetics; Male; Pressure; Proglumide; Receptors, Cholecystokinin; Triglycerides; Ultrasonography

1998
Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors.
    Gastroenterology, 1998, Volume: 115, Issue:3

    Topics: Adult; Cholecystokinin; Cholestyramine Resin; Eating; Electric Stimulation; Esophagogastric Junction; Esophagus; Gallbladder; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Proglumide; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide

1998
[Behavioral and neurochemical study on the role of the brain cholecystokinin system in anxiety].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:5

    Topics: Animals; Anxiety; Biogenic Monoamines; Brain; Cholecystokinin; Disease Models, Animal; Hormone Antagonists; Male; Proglumide; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin

1998
Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility.
    Gastroenterology, 1999, Volume: 116, Issue:1

    Topics: Adolescent; Adult; Cholecystokinin; Fatty Acids; Female; Gallbladder; Gastric Mucosa; Gastrointestinal Motility; Hormone Antagonists; Humans; Male; Middle Aged; Muscle Tonus; Proglumide; Pyloric Antrum; Radioimmunoassay; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Stomach; Structure-Activity Relationship; Ultrasonography

1999
Involvement of endogenous cholecystokinin and somatostatin in gastroprotection induced by intraduodenal fat.
    Journal of clinical gastroenterology, 1998, Volume: 27 Suppl 1

    Topics: Animals; Capsaicin; Cholecystokinin; Denervation; Dinoprostone; Dopamine Agents; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Hormone Antagonists; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oleic Acid; Pepsin A; Proglumide; Rats; Rats, Wistar; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Somatostatin; Stomach Ulcer; Vagotomy

1998
Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves.
    Regulatory peptides, 1999, Jun-30, Volume: 82, Issue:1-3

    Topics: Animals; Cholecystokinin; DNA Replication; Dopamine Agents; Esters; Gabexate; Gastric Mucosa; Gastrins; Guanidines; Hormone Antagonists; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pancreatin; Proglumide; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Cholecystokinin; Regional Blood Flow; RNA, Messenger; Sensory Receptor Cells; Sincalide; Somatostatin; Stomach; Stomach Ulcer

1999
Role of cholecystokinin in the intestinal phase of pancreatic circulation in dogs.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:4

    Topics: Animals; Cholecystokinin; Dogs; Female; Hemodynamics; Hormone Antagonists; Intestines; Male; Milk; Pancreas; Proglumide; Proteins; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Regional Blood Flow

2001
Differential mechanism and site of action of CCK on the pancreatic secretion and growth in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:4

    Topics: Afferent Pathways; Amylases; Animals; Capsaicin; Cholecystokinin; Duodenum; Eating; Lipase; Male; Organ Size; Pancreas; Proglumide; Rats; Rats, Wistar; Sincalide; Trypsin; Trypsinogen; Vagotomy; Vagus Nerve

2003
Long-term bile diversion enhances basal and duodenal oleate-stimulated pancreatic exocrine secretion in dogs.
    The Tohoku journal of experimental medicine, 2004, Volume: 203, Issue:2

    Topics: Animals; Bicarbonates; Bile Ducts; Cholecystokinin; Dogs; Duodenum; Gastric Fistula; Hormone Antagonists; Humans; Oleic Acid; Pancreas; Pancreatic Fistula; Proglumide; Receptor, Cholecystokinin A; Time Factors; Urinary Bladder

2004
The effects of an essential fatty acid compound and a cholecystokinin-8 antagonist on iron deficiency induced anorexia and learning deficits.
    Nutritional neuroscience, 2004, Volume: 7, Issue:2

    Topics: Animal Feed; Animals; Avoidance Learning; Cholecystokinin; Energy Intake; Hormone Antagonists; Iron Deficiencies; Islets of Langerhans; Linoleic Acid; Male; Motor Activity; Peptide Fragments; Proglumide; Rats; Rats, Long-Evans; Swimming; Weight Gain

2004
The effects on diet, anastomotic type, and loxiglumide on gastric emptying following gastrojejunostomy.
    International journal of surgery (London, England), 2009, Volume: 7, Issue:2

    Topics: Anastomosis, Surgical; Animals; Cholecystokinin; Disease Models, Animal; Enteral Nutrition; Female; Gastric Bypass; Gastric Emptying; Hormone Antagonists; Jejunum; Male; Proglumide; Rats; Rats, Wistar; Stomach

2009
Effect of endogenous cholecystokinin on the course of acute pancreatitis in rats.
    World journal of gastroenterology, 2015, Jul-07, Volume: 21, Issue:25

    Topics: Administration, Oral; Animals; Biomarkers; Bombesin; Cell Proliferation; Cholecystokinin; Disease Models, Animal; DNA Replication; Esters; Gabexate; Guanidines; Hormone Antagonists; Insulin Resistance; Male; Pancreas; Pancreatic Function Tests; Pancreatitis; Proglumide; Rats, Wistar; Receptor, Cholecystokinin A; Recovery of Function; Taurocholic Acid; Time Factors

2015