lovastatin and leucine
lovastatin has been researched along with leucine in 10 studies
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Maltese, WA; Repko, EM | 1 |
| Astrand, IM; Chojnacki, T; Dallner, G; Fries, E | 1 |
| Hatton, J; Middleton, B; White, DA | 1 |
| Auclair, M; Dubertret, L; Franchi, J; Gardette, J; Mazière, C; Mazière, JC; Quiec, D; Redziniak, G; Santus, R | 1 |
| Croft, KD; Kelly, JM; Naoumova, RP; Riches, FM; Thompson, GR; Watts, GF | 1 |
| Kanda, Y; Nishio, E; Watanabe, Y | 1 |
| Bertoglio, J; Blaie, S; Bolla, M; Boquet, P; Créminon, C; Degraeve, F; Habib, A; Lévy-Toledano, S; Quéré, I | 1 |
| Hohl, RJ; Holstein, SA; Wohlford-Lenane, CL | 1 |
| Hamadmad, SN; Hohl, RJ | 1 |
Trials
1 trial(s) available for lovastatin and leucine
| Article | Year |
|---|---|
Inhibition of cholesterogenesis decreases hepatic secretion of apoB-100 in normolipidemic subjects.
Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Carbon Isotopes; Cholesterol; Double-Blind Method; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isomerism; Leucine; Lipoproteins; Liver; Lovastatin; Male; Middle Aged; Random Allocation; Reference Values; Regression Analysis; Simvastatin | 1997 |
Other Studies
9 other study(ies) available for lovastatin and leucine
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability.
Topics: Animals; Cell Line; Cholesterol; Cycloheximide; Dolichols; Kinetics; Leucine; Lovastatin; Mevalonic Acid; Protein Processing, Post-Translational; Tritium; Ubiquinone | 1989 |
Inhibition of dolichyl phosphate biosynthesis by compactin in cultured rat hepatocytes.
Topics: Acetates; Acetic Acid; Animals; Cells, Cultured; Cholesterol; Cytidine Triphosphate; Dolichol Phosphates; Glycerol; Leucine; Liver; Lovastatin; Male; Naphthalenes; Phospholipids; Phosphorus Radioisotopes; Phosphorylation; Polyisoprenyl Phosphates; Protein Biosynthesis; Rats; Tritium | 1986 |
A mevalonate requirement for maintenance of fatty acid and protein synthesis during hormonally stimulated development of mammary gland in vitro.
Topics: Acetates; Acetic Acid; Animals; Carbon Radioisotopes; Fatty Acids; Female; Hydroxymethylglutaryl CoA Reductases; Insulin; Leucine; Lovastatin; Mammary Glands, Animal; Mevalonic Acid; Microsomes; Naphthalenes; Organ Culture Techniques; Pregnancy; Prolactin; Protein Biosynthesis; Rabbits; Tritium | 1984 |
Lovastatin enhances the photocytotoxicity of UVA radiation towards cultured N.C.T.C. 2544 human keratinocytes: prevention by cholesterol supplementation and by a cathepsin inhibitor.
Topics: Cathepsins; Cell Line; Cell Survival; Cholesterol; Humans; Keratinocytes; Leucine; Lovastatin; Ultraviolet Rays | 1995 |
Alpha1-adrenoreceptor stimulation causes vascular smooth muscle cell hypertrophy: a possible role for isoprenoid intermediates.
Topics: Adrenergic alpha-Agonists; Animals; Anticholesteremic Agents; Aorta, Thoracic; Carbon Radioisotopes; Cell Count; Cells, Cultured; Cholesterol; Drug Interactions; Farnesol; Hypertrophy; Leucine; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Phenylephrine; Protein Prenylation; Rats; Receptors, Adrenergic, alpha-1; Transferases | 1998 |
Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
Topics: Amides; Aorta; Apoptosis; Bacterial Proteins; Bacterial Toxins; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Interleukin-1; Isoenzymes; Leucine; Lovastatin; Membrane Proteins; Mevalonic Acid; Muscle, Smooth; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Protein Prenylation; Pyridines; rho GTP-Binding Proteins; Time Factors | 2001 |
Isoprenoids influence expression of Ras and Ras-related proteins.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cycloheximide; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; K562 Cells; Leucine; Lovastatin; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation.
Topics: Anti-Bacterial Agents; Anticholesteremic Agents; Antiviral Agents; Biotinylation; Blotting, Western; Cell Line, Tumor; Cell Survival; Dolichols; Dose-Response Relationship, Drug; Erythropoietin; Glycosylation; Humans; Iodine Radioisotopes; Janus Kinase 2; Leucine; Lovastatin; Mevalonic Acid; Phosphorylation; Polyisoprenyl Phosphates; Protein Prenylation; Receptors, Erythropoietin; STAT5 Transcription Factor; Tunicamycin | 2007 |