Page last updated: 2024-08-23

lovastatin and betadex

lovastatin has been researched along with betadex in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's21 (75.00)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heřmánková, E; Hobzová, R; Hromádka, R; Poláková, L; Širc, J; Žák, A1
Francis, SA; Lynch, RD; Schneeberger, EE; Stankewich, MC; Vu, QU1
Burkhart, KM; Johnson, AC; Sacks, BM; Zager, RA1
Danielsen, EM; Hansen, GH; Immerdal, L; Niels-Christiansen, LL; Thorsen, E1
Lipardi, C; Nitsch, L; Zurzolo, C1
Thyberg, J1
Essig, M; Friedlander, G; Laouari, D; Ledoux, S; Michel, JB; Runembert, I; Trugnan, G1
Arispe, N; Doh, M1
Eckert, GP; Kirsch, C; Mueller, WE1
Abe-Dohmae, S; Arakawa, R; Inoue, K; Nishimaki-Mogami, T; Suzuki, S; Tamehiro, N; Tanaka, AR; Ueda, K; Yokoyama, S1
Borchmann, P; Engert, A; Hansen, HP; Kallen, KJ; Lange, H; von Strandmann, EP; von Tresckow, B1
Gniadecki, R1
Anthony, MD; Edwards, RH; Fortin, DL; Kubo, S; Nakamura, K; Troyer, MD1
Fowler, CJ; Sandberg, A1
Bang, B; Gajkowska, B; Gniadecki, R1
Chen, MY; Chou, YC; Tsai, HI; Tsai, LH1
Hamblin, MW; Sjögren, B; Svenningsson, P1
Ertunc, M; Kavalali, ET; Liu, X; Wasser, CR1
Llorente, A; Sandvig, K; van Deurs, B1
Ehehalt, R; Fullekrug, J; Krautter, M; Kulaksiz, H; Sparla, R; Stremmel, W; Zorn, M1
Csempesz, F; Süle, A; Szente, L1
Bee, JW; Bernstone, L; Carter, GC; Harder, T; James, W; Sangani, D1
Cardaba, CM; Mueller, A1
Priotto, S; Repossi, G; Sartori, MJ; Valentich, MA1
Ahn, CM; Chang, J; Chang, YS; Jeon, JH; Kim, HJ; Kim, SK1
Boerner, JL; Bohin, N; Ge, Y; Irwin, ME; Mueller, KL1
Baiersdörfer, M; Kanarek, AM; Kojro, E; Postina, R; Quade-Lyssy, P1
Marceau, F; Parks, A1

Reviews

1 review(s) available for lovastatin and betadex

ArticleYear
Polymeric bile acid sequestrants: Review of design, in vitro binding activities, and hypocholesterolemic effects.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Binding Sites; Drug Design; Humans; Hypercholesterolemia; Molecular Structure; Polymers

2018

Other Studies

27 other study(ies) available for lovastatin and betadex

ArticleYear
Alterations in cell cholesterol content modulate Ca(2+)-induced tight junction assembly by MDCK cells.
    Lipids, 1996, Volume: 31, Issue:8

    Topics: Animals; beta-Cyclodextrins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cholesterol; Cholesterol Oxidase; Cyclodextrins; Dogs; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Kidney; Lovastatin; Tight Junctions; Tricarboxylic Acids

1996
Increased proximal tubular cholesterol content: implications for cell injury and "acquired cytoresistance".
    Kidney international, 1999, Volume: 56, Issue:5

    Topics: Acute Kidney Injury; Animals; beta-Cyclodextrins; Cholesterol; Cholesterol Oxidase; Cyclodextrins; Cytoprotection; Kidney Cortex; Kidney Tubules, Proximal; Lovastatin; Male; Membrane Fluidity; Mice; Phospholipids; Sterol Esterase

1999
Cholesterol depletion of enterocytes. Effect on the Golgi complex and apical membrane trafficking.
    The Journal of biological chemistry, 2000, Feb-18, Volume: 275, Issue:7

    Topics: Animals; beta-Cyclodextrins; Biological Transport; Carbohydrate Metabolism; CD13 Antigens; Cholesterol; Cyclodextrins; Golgi Apparatus; In Vitro Techniques; Intestinal Mucosa; Intestines; Lovastatin; Microscopy, Electron; Microvilli; Sodium-Potassium-Exchanging ATPase; Swine

2000
Detergent-insoluble GPI-anchored proteins are apically sorted in fischer rat thyroid cells, but interference with cholesterol or sphingolipids differentially affects detergent insolubility and apical sorting.
    Molecular biology of the cell, 2000, Volume: 11, Issue:2

    Topics: Animals; beta-Cyclodextrins; Biological Transport; Carboxylic Acids; Cell Line; Cell Membrane; Cell Polarity; Centrifugation, Density Gradient; Cholesterol; Cyclodextrins; Fumonisins; Glycosphingolipids; Glycosylphosphatidylinositols; Golgi Apparatus; Lovastatin; Membrane Proteins; Octoxynol; Proteins; Rats; Rats, Inbred F344; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; Solubility; Thyroid Gland; Transfection

2000
Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2002, Volume: 50, Issue:2

    Topics: Animals; Aorta; beta-Cyclodextrins; Caveolae; Cells, Cultured; Cholesterol; Cholesterol, LDL; Cyclodextrins; Filipin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indicators and Reagents; Lovastatin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Sprague-Dawley

2002
Lovastatin enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: implication of rho-family GTPases.
    Circulation research, 2002, Mar-08, Volume: 90, Issue:4

    Topics: 5'-Nucleotidase; Animals; beta-Cyclodextrins; Cell Hypoxia; Cell Membrane; Cells, Cultured; Cholesterol; Cyclodextrins; Dose-Response Relationship, Drug; Endocytosis; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Platelet Aggregation; Polyisoprenyl Phosphates; Protein Prenylation; Rats; rho GTP-Binding Proteins; RNA, Messenger

2002
Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:12

    Topics: Amyloid beta-Peptides; Animals; Anticholesteremic Agents; beta-Cyclodextrins; Cell Membrane; Cell Survival; Cholesterol; Cyclodextrins; Dose-Response Relationship, Drug; Liposomes; Lovastatin; PC12 Cells; Peptide Fragments; Phosphatidylserines; Rats; Tromethamine; Zinc

2002
Statin effects on cholesterol micro-domains in brain plasma membranes.
    Biochemical pharmacology, 2003, Mar-01, Volume: 65, Issue:5

    Topics: Animals; Anisotropy; beta-Cyclodextrins; Brain; Cell Membrane; Cholesterol; Cyclodextrins; Diphenylhexatriene; Female; Fluorescent Dyes; Gene Expression; Lovastatin; Membrane Proteins; Mice; Mice, Inbred C57BL; Pyrenes; Simvastatin; Synaptosomes; Trinitrobenzenesulfonic Acid

2003
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:3

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; beta-Cyclodextrins; Bucladesine; Calcium Channel Blockers; Cell Line; Cholesterol; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Humans; Hydroxycholesterols; Lipoproteins; Lipoproteins, HDL; Liver X Receptors; Lovastatin; Macrophages; Mice; Nicardipine; Nifedipine; Orphan Nuclear Receptors; Phospholipids; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stereoisomerism; Transfection; Verapamil

2004
Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Apr-01, Volume: 172, Issue:7

    Topics: ADAM Proteins; ADAM17 Protein; Anticholesteremic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cholesterol; Cholesterol Oxidase; Cyclodextrins; Detergents; Filipin; Humans; Ki-1 Antigen; Lovastatin; Membrane Microdomains; Metalloendopeptidases; Metalloproteases; Octoxynol; Solubility; Tissue Inhibitor of Metalloproteinase-3

2004
Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis.
    Biochemical and biophysical research communications, 2004, Jul-16, Volume: 320, Issue:1

    Topics: Apoptosis; beta-Cyclodextrins; Cell Line; Cholesterol; Cholesterol Oxidase; Cyclodextrins; Dose-Response Relationship, Drug; fas Receptor; Filipin; Humans; Keratinocytes; Ligands; Lovastatin; Membrane Fluidity; Membrane Microdomains

2004
Lipid rafts mediate the synaptic localization of alpha-synuclein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-28, Volume: 24, Issue:30

    Topics: alpha-Synuclein; Amino Acid Substitution; Animals; beta-Cyclodextrins; Brain Chemistry; Cell Compartmentation; Cell Membrane Permeability; Cells, Cultured; Cholesterol; Detergents; Digitonin; Fumonisins; HeLa Cells; Hippocampus; Humans; Kidney; Lovastatin; Membrane Lipids; Membrane Microdomains; Mevalonic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Nerve Tissue Proteins; Nystatin; Protein Binding; Rats; Recombinant Fusion Proteins; Sphingolipids; Synucleins; Transfection

2004
Measurement of saturable and non-saturable components of anandamide uptake into P19 embryonic carcinoma cells in the presence of fatty acid-free bovine serum albumin.
    Chemistry and physics of lipids, 2005, Volume: 134, Issue:2

    Topics: Amidohydrolases; Animals; Anticholesteremic Agents; Arachidonic Acids; beta-Cyclodextrins; Carcinoma; Cell Line, Tumor; Cholesterol; Embryo, Mammalian; Endocannabinoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Polyunsaturated Alkamides; Serum Albumin, Bovine

2005
Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes.
    Experimental dermatology, 2005, Volume: 14, Issue:4

    Topics: Apoptosis; beta-Cyclodextrins; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cholesterol; Cholesterol Oxidase; Detergents; Enzyme-Linked Immunosorbent Assay; Filipin; Humans; In Situ Nick-End Labeling; Keratinocytes; Lipids; Lovastatin; Membrane Microdomains; Microscopy, Confocal; Microscopy, Electron; Microscopy, Fluorescence; Time Factors

2005
Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes.
    Brain research, 2006, Aug-09, Volume: 1104, Issue:1

    Topics: Actins; Analysis of Variance; Animals; Aspartic Acid; Astrocytes; beta-Cyclodextrins; Cell Size; Cells, Cultured; Cholesterol; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lovastatin; Microtubule-Associated Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tritium

2006
Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: 5-Methoxytryptamine; Activating Transcription Factor 1; beta-Cyclodextrins; Binding, Competitive; Blotting, Western; Cholesterol; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Fumonisins; HeLa Cells; Humans; Lovastatin; Mevalonic Acid; Phenols; Phosphorylation; Radioligand Assay; Receptors, Serotonin; Serine; Serotonin; Signal Transduction; Sulfonamides; Transfection; Tritium

2006
Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.
    The Journal of physiology, 2007, Mar-01, Volume: 579, Issue:Pt 2

    Topics: Animals; beta-Cyclodextrins; Cells, Cultured; Cholesterol; Disease Models, Animal; Evoked Potentials; Hippocampus; Intracellular Signaling Peptides and Proteins; Lovastatin; Mice; Mice, Knockout; Neuroglia; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptic Vesicles; Vesicle-Associated Membrane Protein 2

2007
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells.
    European journal of cell biology, 2007, Volume: 86, Issue:7

    Topics: beta-Cyclodextrins; Cell Line, Tumor; Cholesterol; Endocytosis; Humans; Lovastatin; Lysosomes; Male; Mevalonic Acid; Neoplasm Proteins; Prostatic Neoplasms; Secretory Vesicles

2007
Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease.
    World journal of gastroenterology, 2008, Mar-14, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Anticholesteremic Agents; beta-Cyclodextrins; Biological Transport; Caco-2 Cells; Carcinoembryonic Antigen; Cell Line, Tumor; Cell Membrane; Cholesterol; Colonic Neoplasms; Humans; Inflammatory Bowel Diseases; Lovastatin

2008
Enhancement of drug solubility in supramolecular and colloidal systems.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:2

    Topics: beta-Cyclodextrins; Chemistry, Pharmaceutical; Colloids; Computer Simulation; Cyclodextrins; Drug Carriers; Drug Stability; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Models, Chemical; Models, Molecular; Molecular Structure; Pyrrolidinones; Simvastatin; Solubility; Surface Tension; Temperature

2009
HIV entry in macrophages is dependent on intact lipid rafts.
    Virology, 2009, Mar-30, Volume: 386, Issue:1

    Topics: Antimetabolites; beta-Cyclodextrins; Cells, Cultured; Filipin; HIV-1; Humans; Lovastatin; Macrophages; Membrane Microdomains; Nystatin; Virus Attachment; Virus Internalization

2009
Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells.
    Biochemical pharmacology, 2009, Oct-15, Volume: 78, Issue:8

    Topics: Animals; Anticholesteremic Agents; beta-Cyclodextrins; Calcium; Caveolae; Cell Line; Cell Membrane; Chemokine CCL3; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate Receptors; Kidney; Lovastatin; Membrane Microdomains; Monocytes; Pertussis Toxin; Receptors, CCR5; Receptors, G-Protein-Coupled; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Simvastatin; Thapsigargin; Time Factors

2009
Trypanosoma cruzi: participation of cholesterol and placental alkaline phosphatase in the host cell invasion.
    Experimental parasitology, 2009, Volume: 122, Issue:1

    Topics: Alkaline Phosphatase; Animals; Anticholesteremic Agents; beta-Cyclodextrins; Cell Line; Cholesterol; gamma-Glutamyltransferase; Humans; Lovastatin; Membrane Microdomains; Mice; Trypanosoma cruzi

2009
Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex.
    Lung cancer (Amsterdam, Netherlands), 2010, Volume: 69, Issue:2

    Topics: beta-Cyclodextrins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cholesterol; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesions; Humans; Lovastatin; Membrane Microdomains; Oncogene Protein pp60(v-src); Phosphorylation; Protein Stability; Protein Transport; Pseudopodia; Receptor Aggregation

2010
Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
    Journal of cellular physiology, 2011, Volume: 226, Issue:9

    Topics: Atorvastatin; Benzylamines; beta-Cyclodextrins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholesterol; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Female; Gefitinib; Heptanoic Acids; Humans; Lovastatin; Membrane Microdomains; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Thiophenes

2011
Statins stimulate the production of a soluble form of the receptor for advanced glycation end products.
    Journal of lipid research, 2013, Volume: 54, Issue:11

    Topics: Animals; beta-Cyclodextrins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cholesterol; Dose-Response Relationship, Drug; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Tricarboxylic Acids

2013
Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.
    Toxicology and applied pharmacology, 2016, 08-15, Volume: 305

    Topics: Amiodarone; Anticholesteremic Agents; Autophagy; beta-Cyclodextrins; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chloroquine; Cholesterol; Cytostatic Agents; Cytotoxins; Human Umbilical Vein Endothelial Cells; Humans; Hydroxychloroquine; Lidocaine; Lovastatin; Lysosomes; Microtubule-Associated Proteins; Poly (ADP-Ribose) Polymerase-1; Procainamide; Quinacrine

2016
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