losartan and verapamil

losartan has been researched along with verapamil in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (25.00)18.2507
2000's10 (35.71)29.6817
2010's10 (35.71)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Assaraf, YG; Borgnia, MJ; Eytan, GD1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baker, KM; Dostal, DE; Du, J; Motel, TJ; Thekkumkara, TJ; Thomas, WG1
Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Schnittler, HJ; Vamvakas, S1
Cohen, A; Erlich, Y; Rosenmann, E; Rosenthal, T1
Barton, M; d'Uscio, LV; Lüscher, TF; Shaw, S1
Fujimura, H; Nishiyama, S; Ohmachi, Y; Okumura, F; Toriumi, W; Yoneda, H1
Borges, AC; Paiva, TB; Prioste, RN; Shimuta, SI1
Lazareth, I1
Anders, RJ; Bakris, G; Fagan, T; Ram, V; Sica, D; Vaitkus, PT1
Armenteros, S; Fernández González, R; Garrido, J; Goicolea, I; Martínez, JM; Moreno Carretero, E; Piniés, J1
Anders, RJ; Calhoun, D; Mansoor, GA; Sica, DA; White, WB1
Bacher, P; Bakris, G; Champion, A; Molitch, M; Sarafidis, P; Sowers, JR; Zhou, Q1
Baskurt, M; Kaya, A; Kucukoglu, S; Okcun, B; Ortak, K; Yigit, Z; Yildiz, A1
Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N1
Buck, A; Calcinaghi, N; Fritschy, JM; Jolivet, R; Keller, AL; Matter, CM; Singh, A; Weber, B; Winnik, S; Wyss, MT1
Böhmer, FD; Kirches, E; Mawrin, C; Pachow, D; Petermann, A; Wallesch, M; Wilisch-Neumann, A1
Bozic, M; Fernandez, E; Freixenet, M; Lopez, I; Panizo, S; Pascual, J; Riera, M; Sevilla, MA; Soler, MJ; Valdivielso, JM1
Awadalla, A; Barakat, TS; El-Ghar, MA; El-Nahas, AR; Elsaadany, MM; Elsawy, EA; Elshal, AM; Ismail, AM; Saleh, HH; Sheir, KZ; Taha, DE; Wafa, EW1
Chen, WB; Chen, YS; Liu, YQ; Qin, ZC; Sun, YY; Zhang, SY1

Reviews

2 review(s) available for losartan and verapamil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Management of Raynaud's phenomenon].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:4

    Topics: Adult; Age Distribution; Calcium Channel Blockers; Female; Humans; Iloprost; Losartan; Male; Middle Aged; Necrosis; Prognosis; Raynaud Disease; Risk Factors; Sex Distribution; Smoking; Vasodilator Agents; Verapamil

2001

Trials

6 trial(s) available for losartan and verapamil

ArticleYear
A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes.
    American journal of hypertension, 2002, Volume: 15, Issue:1 Pt 1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Enalapril; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Vasodilator Agents; Verapamil

2002
[Effect of antihypertensive combinations on arterial pressure, albuminuria, and glycemic control in patients with type II diabetic nephropathy: a randomized study].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:2

    Topics: Aged; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lipids; Losartan; Male; Middle Aged; Prospective Studies; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Vasodilator Agents; Verapamil

2002
Preventing increases in early-morning blood pressure, heart rate, and the rate-pressure product with controlled onset extended release verapamil at bedtime versus enalapril, losartan, and placebo on arising.
    American heart journal, 2002, Volume: 144, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Electrocardiography, Ambulatory; Enalapril; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Statistics, Nonparametric; Systole; Verapamil

2002
Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study.
    Journal of the cardiometabolic syndrome, 2008,Winter, Volume: 3, Issue:1

    Topics: Analysis of Variance; Chi-Square Distribution; Diabetes Mellitus; Diuretics; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Indoles; Insulin Resistance; Losartan; Male; Metabolic Syndrome; Middle Aged; Renin-Angiotensin System; Verapamil

2008
Comparison of rate and rhythm control in hypertension patients with atrial fibrillation.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atrial Fibrillation; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; Electric Countershock; Female; Follow-Up Studies; Humans; Hypertension; Losartan; Male; Metoprolol; Middle Aged; Survival Analysis; Treatment Outcome; Verapamil

2008
A randomised controlled trial evaluating renal protective effects of selenium with vitamins A, C, E, verapamil, and losartan against extracorporeal shockwave lithotripsy-induced renal injury.
    BJU international, 2017, Volume: 119, Issue:1

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Ascorbic Acid; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Kidney; Lithotripsy; Losartan; Male; Selenium; Verapamil; Vitamin A; Vitamin E; Vitamins; Wounds and Injuries

2017

Other Studies

20 other study(ies) available for losartan and verapamil

ArticleYear
Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity.
    The Journal of biological chemistry, 1996, Feb-09, Volume: 271, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; CHO Cells; Clone Cells; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Emetine; Gramicidin; Ionophores; Kinetics; Mathematics; Models, Theoretical; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Valinomycin

1996
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: rapid desensitization by angiotensin II.
    Molecular and cellular biochemistry, 1995, May-10, Volume: 146, Issue:1

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Base Sequence; Calcium; Cell Membrane; CHO Cells; Concanavalin A; Cricetinae; Gene Expression; Guanosine Triphosphate; Imidazoles; Losartan; Membrane Potentials; Molecular Sequence Data; Pyridines; Rats; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Tetrazoles; Transfection; Verapamil

1995
Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10, Issue:8

    Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; Cycloheximide; DNA; Hypertrophy; Imidazoles; Kidney; LLC-PK1 Cells; Losartan; Oligopeptides; Protein Synthesis Inhibitors; Proteins; Swine; Tetrazoles; Verapamil

1995
Effects of enalapril, losartan, and verapamil on blood pressure and glucose metabolism in the Cohen-Rosenthal diabetic hypertensive rat.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Disease Models, Animal; Enalapril; Glucose; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Verapamil

1997
Losartan but not verapamil inhibits angiotensin II-induced tissue endothelin-1 increase: role of blood pressure and endothelial function.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred WKY; Receptors, Endothelin; Time Factors; Vasoconstriction; Vasodilation; Vasodilator Agents; Verapamil

1998
Involvement of angiotensin II in development of spontaneous nephrosis in Dahl salt-sensitive rats.
    European journal of pharmacology, 1998, Dec-04, Volume: 362, Issue:2-3

    Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Cholesterol; Glucocorticoids; Hypertension; Imidazoles; Imidazolidines; Losartan; Male; Methylprednisolone; Nephrosis; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Verapamil

1998
Different pathways for Ca2+ mobilization by angiotensin II and carbachol in the circular muscle of the guinea-pig ileum.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Isradipine; Losartan; Male; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nickel; Nifedipine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Vasoconstrictor Agents; Verapamil

1999
Adult hypertension: reducing cardiovascular morbidity and mortality.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diltiazem; Diuretics; Drug Evaluation; Health Behavior; Humans; Hypertension; Losartan; Obesity; Renal Insufficiency; Sodium; Stroke; Verapamil

2005
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
    Life sciences, 2010, Jan-02, Volume: 86, Issue:1-2

    Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil

2010
Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension.
    Stroke, 2013, Volume: 44, Issue:7

    Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Losartan; Male; Microscopy, Fluorescence, Multiphoton; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spectrometry, X-Ray Emission; Verapamil

2013
Re-evaluation of cytostatic therapies for meningiomas in vitro.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Erlotinib Hydrochloride; Humans; Hydroxyurea; Losartan; Meningeal Neoplasms; Meningioma; Metformin; Mifepristone; Neurofibromin 2; Promoter Regions, Genetic; Quinazolines; Radiation Tolerance; Tamoxifen; Temozolomide; Tumor Suppressor Proteins; Verapamil

2014
High phosphate diet increases arterial blood pressure via a parathyroid hormone mediated increase of renin.
    Journal of hypertension, 2014, Volume: 32, Issue:9

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diet; Kidney; Losartan; Male; Parathyroid Hormone; Parathyroidectomy; Phosphates; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Verapamil

2014
Losartan Potassium and Verapamil Hydrochloride Compound Transdermal Drug Delivery System: Formulation and Characterization.
    International journal of molecular sciences, 2022, Oct-27, Volume: 23, Issue:21

    Topics: Administration, Cutaneous; Delayed-Action Preparations; Drug Delivery Systems; Losartan; Skin Absorption; Verapamil

2022