losartan and telmisartan

losartan has been researched along with telmisartan in 161 studies

Research

Studies (161)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (4.97)18.2507
2000's75 (46.58)29.6817
2010's64 (39.75)24.3611
2020's14 (8.70)2.80

Authors

AuthorsStudies
Entzeroth, M; Hasselbach, KM; Hauel, NH; Mihm, G; Narr, B; Ries, UJ; van Meel, JC; Wienen, W; Wittneben, H1
Berellini, G; Cruciani, G; Mannhold, R1
Lombardo, F; Obach, RS; Waters, NJ1
Guo, XZ; Li, BG; Liu, XX; Lu, XX; Shi, L; Wang, R1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T1
Fei, F; Han, XF; Hao, LP; Li, ZH; Liang, AH; Liu, T; Wang, JL; Xu, D; Xue, WZ; Zhang, J; Zhou, ZM2
Abad-Santos, F; Cabaleiro, T; López-Rodríguez, R; Novalbos, J; Ochoa, D; Prieto-Pérez, R; Román, M; Talegón, M; Wojnicz, A1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Fei, F; Han, XF; Hao, LP; Liang, AH; Liu, T; Tao, WC; Wang, JL; Wang, YC; Xu, D; Xue, WZ; Yu, WF; Zhang, J; Zhou, ZM1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bao, X; Chen, Z; Da, Y; Li, F; Ren, H; Wang, L; Wu, D; Yan, Y; Zhu, W1
Boisbrun, M; Dupuis, F; Flament, S; Foulquier, S; Grillier-Vuissoz, I; Grimaud, L; Henrion, D; Lartaud, I; Meyer, M; Monard, G1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM1
Foster, H; Foster, R; Philippou, H; Wilson, C1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bauer, JH; Reams, GP1
Haigh, RM; Redemann, N; van Meel, JC1
Amann, K; Bohlender, J; Drab, M; Ganten, D; Wagner, J; Wienen, W1
Kirk, JK1
Kaplan, NM1
Messerli, FH1
Lacourcière, Y; Mallion, J; Siche, J1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR1
Grossman, E; Messerli, FH; Neutel, JM1
Howes, L; Wong, W1
Vidt, DG1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Ramahi, TM1
Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA1
Magometschnigg, D1
Akesolo, U; Alonso, RM; González, L; Jiménez, RM1
Howes, LG; Tran, D1
Rapi, J1
Fakouhi, K; He, W; Krause, S; Krum, H; Nolly, H; Roniker, B; Workman, D1
Balt, JC; Nap, A; Pfaffendorf, M; Van Zwieten, PA1
Klein, C; Meinicke, TW; Neutel, JM; Schumacher, H1
Brunner, HR; Burnier, M; Forclaz, A; Maillard, M; Nussberger, J1
Alföldi, S1
Byrne, M; Gil-Extremera, B; Lacourcière, Y; Mueller, O; Williams, L1
Terra, SG1
Battegay, E; Dieterle, T; Martina, B; Sigle, JP; Surber, C1
Kolloch, RE; Meinicke, TW; Neutel, JM; Plouin, PF; Schumacher, H1
Cramer, MJ; Hettiarachchi, R; Koval, S; Neutel, JM; Smith, DH1
Ballary, C; Desai, A; Dongre, N; Samra, SS1
Jermendy, G; Matos, L; Winkler, G1
Dominiak, P; Häuser, W1
Avery, MA; Benson, SC; Chittiboyina, A; Desai, P; Ho, CI; Kurtz, TW; Pershadsingh, HA; Pravenec, M; Qi, N; Wang, J1
Clasen, R; Janke, J; Kintscher, U; Schupp, M; Unger, T1
Arakawa, K1
Huang, HC; Huang, LC; Kuo, WK; Lee, CM; Lee, YT; Lin, CS; Sheu, SH; Tsai, CW; Tseng, WK; Wang, JS1
Bai, J; Cai, NS; Cheng, NN; Fan, WH; Guo, JX; Guo, JZ; Ke, YN; Lu, ZY; Sheng, LH; Tang, B; Zhu, JR1
Doggrell, SA1
Luño, J1
Asayama, K; Hashimoto, J; Imai, Y; Kikuya, M; Metoki, H; Nishimura, T; Ohkubo, T; Totsune, K1
Pershadsingh, HA1
Feng, YQ; Nie, J; Wei, F; Zhang, M; Zhang, YF1
Chrysant, SG; Littlejohn, TW; Neutel, JM; Singh, A1
Jin, D; Kirimura, K; Mino, Y; Miyazaki, M; Muramatsu, M; Takai, S; Yoshikawa, K1
Lacourcière, Y; Neutel, JM; Schumacher, H1
Devereux, RB; Krauser, DG1
Boschmann, M; Engeli, S; Gorzelniak, K; Janke, J; Jordan, J; Luft, FC; Nystrom, FH; Sauma, L; Schupp, M; Sharma, AM1
Bianchetti, MG; Fossali, E; Ghiglia, S; Limoni, C; Meier, CM; Salice, P; Simonetti, GD1
Behlouli, H; Hudson, M; Humphries, K; Pilote, L; Sheppard, R; Tu, JV1
Bahadir, MA; Bahadir, O; Oguz, A; Uzunlulu, M1
Mitsuyama, S1
Petkow-Dimitrow, P1
Dai, Q; Sun, B; Xu, M; Yao, M1
Bedette, D; Fontes, MA; Santos, RA1
Leenen, FH; Liang, B1
Cheng, JW; Lu, GC; Xi, GL1
Hyakukoku, M; Kazdová, L; Kren, V; Kurtz, TW; Pravenec, M; Qi, NR; Simáková, M; Sugimoto, K; Zídek, V1
Bakris, G; Burgess, E; Davidai, G; Koval, S; Weir, M1
Ikee, R; Kobayashi, S; Maesato, K; Mano, T; Moriya, H; Ohtake, T; Oka, M1
Balduini, CL; Fiore, CE; Granata, A; Pecci, A1
Fujita, T; Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K1
Damodar, A; Panesar, M1
Georgescu, EF1
Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Nabe, K; Wada, Y1
Chan, CM; Wong, KS; Woo, KT1
Hatzitolios, A; Ntaios, G; Savopoulos, C1
Burgueño, AL; Carabelli, J; Pirola, CJ; Rosselli, MS; Schuman, M; Sookoian, S1
Furukata, S; Ishimitsu, T; Matsuoka, H; Minami, J1
Kuji, T; Masuda, S; Okano, Y; Tamura, K; Tochikubo, O; Umemura, S1
Falvey, H; Lowy, A; Müller, E; Nixon, RM1
Bichu, P; Khan, A; Nistala, R; Sowers, JR; Whaley-Connell, A1
Ayala, C; Clavijo, S; Contreras, Y; del Rosario Brunetto, M; Delgado, Y; Estela, JM; Gallignani, M; Martin, VC; Ovalles, F; Torres, D1
Harada, N; Okajima, K; Shimozawa, N1
Bähr, IN; Fleck, E; Fritzsche, J; Goebel, M; Gust, R; Hässle, PL; Kappert, K; Kaufmann, J; Kintscher, U; Ott, I; Stawowy, P; Tsuprykov, O; Unger, T1
Azuma, K; Dejima, T; Kanaoka, T; Maeda, A; Masuda, S; Ohsawa, M; Tamura, K; Umemura, S; Wakui, H; Yanagi, M1
Brody, R; Grossman, E; Peleg, E; Sharabi, Y1
Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N1
Masuda, S; Okano, Y; Ozawa, M; Tamura, K; Tochikubo, O; Umemura, S1
Neldam, S1
Bhuiyan, MA; Hossain, M; Nagatomo, T; Nakamura, T; Ozaki, M1
Hamada, T; Hirai, M; Hisatome, I; Igawa, O; Kato, M; Kondo, T; Mizuta, E; Ninomiya, H; Shigemasa, C; Yamada, K; Yamamoto, Y1
Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J1
Czuczwar, SJ; Jakubus, T; Janowska, A; Tochman-Gawda, A; Łukawski, K1
Horiuchi, M; Iwai, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K1
Fujiwara, N; Koide, H; Nakamura, T; Sato, E; Sugaya, T; Ueda, Y1
Hu, ZP; Qian, HY; Wang, BN; Wang, Y; Wei, W; Zhou, Q1
Akaike, A; Hongo, H; Kihara, T; Niidome, T; Sugimoto, H; Wu, X1
Bilo, G; Mancia, G; Parati, G; Schumacher, H1
Ge, J; Gong, H; Komuro, I; Li, L; Lin, L; Wu, J; Zhou, N; Zou, Y1
Chang, CH; Lai, MS; Lin, JW; Wu, LC1
Gardiner, P; Paine, SW1
Hasegawa, H; Kobayashi, Y; Komuro, I; Mizuguchi, T; Namiki, T; Narumi, H; Ohtsuka, M; Takano, H1
Fujishima, H; Fujita, H; Komatsu, K; Morii, T; Narita, T; Sakamoto, T; Takahashi, T; Yamada, Y1
Gómez-Cabrera, MC; Sanchis-Gomar, F; Viña, J1
Cao, K; Chen, XM; Huang, HJ; Huang, J; Lu, XZ; Qin, XY; Yang, XH; Yong, YH; Zheng, HJ; Zong, WN1
Hasegawa, H; Kameda, Y; Kobayashi, Y; Komuro, I; Kubota, A; Takano, H1
Azuma, J; Iekushi, K; Iwabayashi, M; Kusunoki, H; Morishita, R; Okayama, K; Otsu, R; Rakugi, H; Sanada, F; Taniyama, Y1
Corbalan, JJ; Jacob, RF; Jacoby, A; Kubant, R; Louka, F; Malinski, T; Mason, RP1
Kobara, M; Nakata, T; Noda, K; Toba, H; Tojo, C; Wang, J1
Horiuchi, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Ohshima, K; Shudou, M; Tsukuda, K1
Bougaki, M; Chang, K; Muroya, M; Uchida, K; Yamada, Y1
Abbas, H; Ali, R; Geirsson, A; Hashim, S; Li, W; Sanchez, JA; Singh, M; Tellides, G1
Han, J; Kim, HK; Kim, N; Ko, KS; Ko, TH; Lee, SR; Lee, SY; Lim, SE; Long, le T; Nilius, B; Noh, JH; Rhee, BD; Won, du N; Youm, JB1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
Czuczwar, SJ; Jakubus, T; Janowska, A; Lukawski, K; Raszewski, G1
Baek, IH; Kwon, KI; Lee, BY; Lee, ES1
Barykina, IN; Chumachok, EV; Ledyaeva, AA; Mazina, G; Nedogoda, SV; Salasyuk, AS; Tsoma, VV1
Antoniou, T; Camacho, X; Gomes, T; Juurlink, DN; Mamdani, MM; Yao, Z1
Doddapaneni, R; Godugu, C; Jackson, T; Marepally, S; Patel, AR; Singh, M1
Hamada, T; Haruaki, N; Hirota, Y; Hisatome, I; Kato, M; Kosaka, H; Kotake, H; Kuwabara, M; Miyazaki, S; Mizuta, E; Nakamura, H; Ogino, K; Ohtahara, A; Omodani, H; Taniguchi, S; Watanabe, A; Watanabe, M; Yamamoto, K1
Goto, SN; Mizuno, Y; Niwa, M; Takagi, H; Umemoto, T1
Asai, S; Kanou, N; Nakayama, T; Nishida, Y; Susa, N; Takahashi, Y1
Kobara, M; Nakata, T; Ohigashi, M; Toba, H; Wang, J1
Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC1
Komano, H; Liu, J; Liu, S; Maeda, T; Tanabe, C; Zou, K1
Imai, K; Iwazaki, A; Nakagawa, M; Nakanishi, K; Takahashi, K; Tamezane, Y; Tanaka, K1
D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F1
Brown, SA; Coleman, AE; Jenkins, TL; Schmiedt, CW1
Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M1
Bojarska, A; Brzozowski, T; Celinski, K; Czechowska, G; Dudka, J; Korolczuk, A; Madro, A; Wojcicka, G1
Aguila, MB; Barbosa-da-Silva, S; Graus-Nunes, F; Mandarim-de-Lacerda, CA; Marinho, TS; Souza-Mello, V1
Chies, AB; da Silva Mansano, N; Jorge, IF; Spadella, MA; Viani, GA1
Bu, Q; Cen, X; Gu, H; Guo, W; Jiang, L; Kong, J; Li, Y; Long, H; Luo, L; Shao, X; Tian, J; Zhao, Y; Zhu, R1
Cavalim Vale, AP; Chagas, EFB; Chies, AB; da Silva, TP; Dos Santos, G; Mansano, NDS; Spadella, MA1
Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I1
Banerji, S; Mehrpour, O; Nakhaee, S; Shirazi, FM1
Benard, F; Bennewith, KL; Cederberg, RA; Colpo, N; Firmino, NS; Franks, SE; Lee, CM; Lin, KS; Pan, J; Wadsworth, BJ1
Fahmy, A; Hegazy, N; Rezq, S1
Aiglova, R; Cernicek, V; Danek, J; Gloger, V; Lazarova, M; Pavlu, L; Precek, J; Schee, A; Skala, T; Taborsky, M; Vicha, M1
Dantas, ASCL; de Lima, PC; de Souza, MN; Ferreira, LODS; Lima, MED; Maranho, RLDN; Monteiro, MA; Novotny, TS; Ochs, SM; Santana, DS1
Duarte, M; Ignacio, FC; Nicolosi, L; Pelorosso, FG; Rothlin, RP; Salgado, MV; Vetulli, H1
Abbood, SK; Al-Khrasani, M; Apenberg, J; Balogh, M; Benyhe, S; Essmat, N; Galambos, AR; Karádi, DÁ; Király, K; Lakatos, PP; Riba, P; Szökő, É; Szűcs, E; Tábi, T; Varga, ZV1
Liang, H; Tang, T; Xie, M1
Jeong, HE; Kim, JS; Ko, H; Lim, MJ; Shin, JY; Yoo, YG1
Baratta, F; Battaglia, V; Ben-Shabat, S; Brusa, P; Collino, M; Dahan, A; Fleisher-Berkovich, S; Sharon, N; Ventura, Y1

Reviews

34 review(s) available for losartan and telmisartan

ArticleYear
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs.
    Archives of internal medicine, 1995, Jul-10, Volume: 155, Issue:13

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

1995
Angiotensin-II receptor antagonists: their place in therapy.
    American family physician, 1999, Volume: 59, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan

1999
Angiotensin II receptor antagonists in the treatment of hypertension.
    American family physician, 1999, Sep-15, Volume: 60, Issue:4

    Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan

1999
. . . and losartan was no better than placebo.
    Journal of human hypertension, 1999, Volume: 13, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Humans; Hypertension; Losartan; Telmisartan

1999
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
    Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13

    Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes

2000
Angiotensin receptor antagonists.
    Australian family physician, 2000, Volume: 29, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles

2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
    Postgraduate medicine, 2001, Volume: 109, Issue:4

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan

2001
[Angiotensin receptor blockers--significance for the therapy of hypertension].
    Wiener medizinische Wochenschrift (1946), 2001, Volume: 151, Issue:7-8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan

2001
Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema?
    Drug safety, 2002, Volume: 25, Issue:2

    Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles

2002
[Irbesartan: a new possibility in the treatment of hypertension].
    Orvosi hetilap, 2002, May-26, Volume: 143, Issue:21

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2002
[Diurnal blood pressure control in the optimal treatment of hypertension].
    Orvosi hetilap, 2003, May-04, Volume: 144, Issue:18 Suppl 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan

2003
Comparison of telmisartan versus losartan: meta-analysis of titration-to-response studies.
    Blood pressure monitoring, 2003, Volume: 8, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Telmisartan; Titrimetry

2003
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].
    Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2003
[Development of combined drugs (ARB and diuretics)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Design; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney Tubules, Proximal; Losartan; Olmesartan Medoxomil; Practice Guidelines as Topic; Renin-Angiotensin System; Sodium; Telmisartan; Tetrazoles

2004
Editorial overview: The 'sartans': is it premature to consider PPARgamma receptor agonism a bonus?
    Current opinion in investigational drugs (London, England : 2000), 2005, Volume: 6, Issue:3

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Hypertension; Irbesartan; Losartan; PPAR gamma; Rats; Rats, Zucker; Telmisartan; Tetrazoles

2005
[Renin-angiotensin system in diabetic nephropathy].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2005, Volume: 25 Suppl 2

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Drug Therapy, Combination; Homeostasis; Humans; Lisinopril; Losartan; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Telmisartan

2005
Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-gamma.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:5-6

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Irbesartan; Losartan; Metabolic Syndrome; PPAR gamma; Telmisartan; Tetrazoles

2006
Comparison of fixed-dose combinations of telmisartan/hydrochlorothiazide 40/12.5 mg and 80/12.5 mg and a fixed-dose combination of losartan/hydrochlorothiazide 50/12.5 mg in mild to moderate essential hypertension: pooled analysis of two multicenter, pros
    Clinical therapeutics, 2005, Volume: 27, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Telmisartan

2005
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
    Herz, 2006, Volume: 31, Issue:4

    Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Carbazoles; Carvedilol; Chi-Square Distribution; Cohort Studies; Coronary Disease; Death, Sudden, Cardiac; Diuretics; Drug Therapy, Combination; Echocardiography; Electroencephalography; Enalapril; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Logistic Models; Losartan; Male; Multivariate Analysis; Prognosis; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Risk Assessment; Risk Factors; Sex Factors; Stroke; Survival Analysis; Telmisartan

2006
[ARB: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, May-28, Volume: 65 Suppl 5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan

2007
[New therapeutic targets for ACE inhibitors and angiotensin receptor blockers].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypertension; Losartan; Metabolic Syndrome; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Risk Reduction Behavior; Telmisartan; Treatment Outcome

2007
Meta-analysis of randomized controlled trials comparing telmisartan with losartan in the treatment of patients with hypertension.
    American journal of hypertension, 2008, Volume: 21, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Research Design; Telmisartan; Treatment Outcome

2008
Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option?
    Advances in therapy, 2008, Volume: 25, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Fatty Liver; Humans; Insulin Resistance; Losartan; Metabolic Syndrome; Renin-Angiotensin System; Telmisartan; Tetrazoles

2008
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.
    International journal of clinical practice, 2009, Volume: 63, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Losartan; Mineralocorticoid Receptor Antagonists; PPAR gamma; Proteinuria; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Treatment Outcome

2009
Choosing an angiotensin-receptor blocker: blood pressure lowering, cardiovascular protection or both?
    Future cardiology, 2010, Volume: 6, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Losartan; Ramipril; Risk Factors; Telmisartan; Tetrazoles

2010
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.
    Journal of hypertension, 2010, Volume: 28, Issue:11

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Databases, Factual; Female; Humans; Losartan; Male; Ramipril; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals.
    Journal of hypertension, 2011, Volume: 29, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Case-Control Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Neoplasms; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles

2011
Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Case-Control Studies; Comorbidity; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Humans; Incidence; Logistic Models; Losartan; Male; Middle Aged; Neoplasms; Odds Ratio; Publication Bias; Risk Assessment; Risk Factors; Taiwan; Telmisartan; Tetrazoles

2011
A meta-analysis of randomized trials of telmisartan versus losartan for reduction of ambulatory blood pressure.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:11

    Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Telmisartan

2013
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
    Clinical cardiology, 2023, Volume: 46, Issue:8

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan

2023

Trials

31 trial(s) available for losartan and telmisartan

ArticleYear
ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension.
    Journal of human hypertension, 1999, Volume: 13, Issue:10

    Topics: Adolescent; Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Safety; Telmisartan; Treatment Outcome

1999
Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Eplerenone; Female; Headache; Heart Rate; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Patient Dropouts; Renin-Angiotensin System; Spironolactone; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2002
Long-term efficacy and tolerability of telmisartan as monotherapy and in combination with other antihypertensive medications.
    Blood pressure, 2002, Volume: 11, Issue:5

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Diastole; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Safety; Sodium Chloride Symporter Inhibitors; Systole; Telmisartan

2002
Angiotensin II receptor blockade: is there truly a benefit of adding an ACE inhibitor?
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:1

    Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Humans; Losartan; Male; Renin-Angiotensin System; Single-Blind Method; Telmisartan

2003
Efficacy and tolerability of fixed-dose combinations of telmisartan plus HCTZ compared with losartan plus HCTZ in patients with essential hypertension.
    International journal of clinical practice, 2003, Volume: 57, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan

2003
Effects of telmisartan and losartan on left ventricular mass in mild-to-moderate hypertension. A randomized, double-blind trial.
    Cardiology, 2003, Volume: 99, Issue:3

    Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure Determination; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Echocardiography, Doppler; Female; Follow-Up Studies; Humans; Hypertension; Losartan; Male; Middle Aged; Probability; Prospective Studies; Severity of Illness Index; Statistics, Nonparametric; Telmisartan; Treatment Outcome; Ventricular Function, Left

2003
Telmisartan vs losartan plus hydrochlorothiazide in the treatment of mild-to-moderate essential hypertension--a randomised ABPM study.
    Journal of human hypertension, 2003, Volume: 17, Issue:8

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Determination; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Telmisartan; Treatment Outcome

2003
Comparison of the efficacy, safety and tolerability of telmisartan with losartan in Indian patients with mild to moderate hypertension: a pilot study.
    Journal of the Indian Medical Association, 2003, Volume: 101, Issue:5

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Double-Blind Method; Female; Humans; Hypertension; India; Losartan; Male; Middle Aged; Pilot Projects; Prospective Studies; Telmisartan

2003
A double-blind comparison of the efficacy and tolerability of telmisartan 40-80 mg vs. losartan 50-100 mg in Taiwanese hypertensive patients.
    International journal of clinical practice. Supplement, 2004, Issue:145

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Patient Compliance; Telmisartan

2004
Efficacy and safety of telmisartan vs. losartan in control of mild-to-moderate hypertension: a multicentre, randomised, double-blind study.
    International journal of clinical practice. Supplement, 2004, Issue:145

    Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Telmisartan

2004
Telmisartan/Hydrochlorothiazide in comparison with losartan/hydrochlorothiazide in managing patients with mild-to-moderate hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:7

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged; Severity of Illness Index; Telmisartan; Treatment Outcome

2005
Palatability of angiotensin II antagonists among nephropathic children.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Child; Child, Preschool; Female; Humans; Irbesartan; Kidney Diseases; Losartan; Male; Patient Compliance; Patient Satisfaction; Smell; Taste; Telmisartan; Tetrazoles; Valine; Valsartan

2007
Effects of telmisartan and losartan on insulin resistance in hypertensive patients with metabolic syndrome.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:1

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Cholesterol, HDL; Fasting; Female; Humans; Hypertension; Insulin Resistance; Losartan; Male; Metabolic Syndrome; Middle Aged; Telmisartan

2007
Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy.
    Kidney international, 2008, Volume: 74, Issue:3

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Creatinine; Diabetic Nephropathies; Double-Blind Method; Female; Half-Life; Humans; Hypertension; Losartan; Male; Middle Aged; Proteinuria; Telmisartan

2008
Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:1

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan

2009
Comparison of therapies between fixed-dose telmisartan/hydrochlorothiazide and losartan/hydrochlorothiazide in patients with mild to moderate hypertension.
    International heart journal, 2009, Volume: 50, Issue:1

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Telmisartan; Treatment Outcome

2009
Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Autonomic Nervous System; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Health Surveys; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Telmisartan; Tetrazoles; Valine; Valsartan

2009
Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Movement; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Muscle Cells; PPAR gamma; Telmisartan; Tetrazoles

2009
Effects of angiotensin II type 1 receptor blocker on ambulatory blood pressure variability in hypertensive patients with overt diabetic nephropathy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Ankle Brachial Index; Benzimidazoles; Benzoates; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diabetic Nephropathies; Double-Blind Method; Electrocardiography; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Proteinuria; Regression Analysis; Telmisartan; Young Adult

2009
Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:8

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Sympathetic Nervous System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:2

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lipids; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Uric Acid

2010
Renoprotective Effects of Various Angiotensin II Receptor Blockers in Patients with Early-Stage Diabetic Nephropathy.
    Kidney & blood pressure research, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fatty Acid-Binding Proteins; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome

2010
Fixed-dose telmisartan/hydrochlorothiazide in comparison with losartan/hydrochlorothiazide in decreasing serum hepatocyte growth factor and improving endothelial dysfunction in hypertensive patients.
    International heart journal, 2010, Volume: 51, Issue:4

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Cohort Studies; Drug Combinations; Endothelins; Endothelium, Vascular; Female; Hepatocyte Growth Factor; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Nitric Oxide; Telmisartan

2010
Effects of telmisartan and losartan on cardiovascular protection in Japanese hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:11

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Benzimidazoles; Benzoates; Cardiovascular Diseases; Carotid Intima-Media Thickness; Female; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Japan; Losartan; Male; Middle Aged; Prospective Studies; Risk Factors; Severity of Illness Index; Single-Blind Method; Telmisartan; Treatment Outcome

2011
Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Benzimidazoles; Benzoates; Cross-Over Studies; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Japan; Losartan; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Telmisartan; Tyrosine

2011
Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hypertension; Imidazoles; Japan; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2012
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Randomized trial of perindopril, enalapril, losartan and telmisartan in overweight or obese patients with hypertension.
    Clinical drug investigation, 2013, Volume: 33, Issue:8

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Obesity; Overweight; Perindopril; Single-Blind Method; Telmisartan

2013
A comparative study on the effectiveness of losartan/hydrochlorothiazide and telmisartan/hydrochlorothiazide in patients with hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:4

    Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Treatment Outcome; Uric Acid

2014
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10

    Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan

2015
Attenuation of the pressor response to exogenous angiotensin by angiotensin receptor blockers and benazepril hydrochloride in clinically normal cats.
    American journal of veterinary research, 2015, Volume: 76, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cats; Cross-Over Studies; Irbesartan; Losartan; Telmisartan; Tetrazoles

2015

Other Studies

96 other study(ies) available for losartan and telmisartan

ArticleYear
6-Substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships.
    Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Binding Sites; Blood Pressure; Male; Models, Molecular; Rats; Rats, Wistar; Receptors, Angiotensin; Structure-Activity Relationship; Telmisartan

1993
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring.
    Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24

    Topics: Adrenal Cortex; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cattle; Dogs; Heart Rate; Heterocyclic Compounds, 1-Ring; Inhibitory Concentration 50; Receptors, Angiotensin

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents

2011
Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Blood Pressure; Drug Design; Models, Molecular; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1

2012
Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT₁ receptor antagonists.
    Bioorganic & medicinal chemistry, 2012, Jul-15, Volume: 20, Issue:14

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Design; Models, Molecular; Protein Binding; Rabbits; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Structure-Activity Relationship

2012
Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Alleles; Angiotensin Receptor Antagonists; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Female; Half-Life; Humans; Male; Polymorphism, Genetic; Reference Values; Sex Factors

2013
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Nonpeptidic angiotensin II AT₁ receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Receptor, Angiotensin, Type 1; Structure-Activity Relationship

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
N-Phenyl indole derivatives as AT1 antagonists with anti-hypertension activities: Design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Design; Hypertension; Indoles; Molecular Structure; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Structure-Activity Relationship

2016
Synthesis and evaluation of new designed multiple ligands directed towards both peroxisome proliferator-activated receptor-γ and angiotensin II type 1 receptor.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Chromans; Drug Design; Humans; Imidazoles; Ligands; Male; MCF-7 Cells; Molecular Docking Simulation; PPAR gamma; Rats, Wistar; Receptor, Angiotensin, Type 1; Triazoles

2018
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
    European journal of medicinal chemistry, 2020, Jun-01, Volume: 195

    Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan

2020
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Hypotensive effects of the angiotensin II antagonist telmisartan in conscious chronically-instrumented transgenic rats.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Imidazoles; Losartan; Rats; Telmisartan; Tetrazoles

1996
Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:2

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Captopril; Cerebrovascular Disorders; Gene Expression; Hypertension; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Telmisartan

1998
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan

2000
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
    Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3

    Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2001
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.
    Journal of hypertension, 2001, Volume: 19, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Captopril; Decerebrate State; Electric Stimulation; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Synaptic Transmission; Telmisartan; Tetrazoles

2001
Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Irbesartan; Losartan; Male; Mesenteric Arteries; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sympathetic Nervous System; Telmisartan; Tetrazoles; Vasoconstrictor Agents

2001
Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists.
    Electrophoresis, 2002, Volume: 23, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Chemical Fractionation; Electrophoresis, Capillary; Imidazoles; Irbesartan; Losartan; Mathematical Computing; Molecular Structure; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2002
Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta.
    Journal of hypertension, 2002, Volume: 20, Issue:9

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Irbesartan; Losartan; Norepinephrine; Osmolar Concentration; Rabbits; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission; Telmisartan; Tetrazoles

2002
[Lowering blood pressure with sartans. Are there differences?].
    MMW Fortschritte der Medizin, 2002, Nov-21, Volume: 144, Issue:47

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Cross-Over Studies; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Valine; Valsartan

2002
Cardiology patient page. Angiotensin receptor blockers.
    Circulation, 2003, Jun-24, Volume: 107, Issue:24

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2003
[Dosage equivalents of AT1-receptor antagonists available in Germany].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44

    Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan

2003
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Drug Evaluation, Preclinical; Gene Expression Regulation; Imidazoles; Insulin; Irbesartan; Losartan; Male; Mice; Models, Molecular; Myoblasts; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Structure-Activity Relationship; Telmisartan; Tetrazoles; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Triglycerides; Valine; Valsartan; Weight Gain

2004
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.
    Circulation, 2004, May-04, Volume: 109, Issue:17

    Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Genes, Reporter; Imidazoles; Insulin Resistance; Irbesartan; Losartan; Luciferases; Mice; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Telmisartan; Tetrazoles; Thiophenes; Transcription Factors; Transfection

2004
[Despite drug treatment, ever second hypertensive patient with morning blood pressure too high].
    MMW Fortschritte der Medizin, 2004, Aug-19, Volume: 146, Issue:33-34

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Drug Administration Schedule; Humans; Hypertension; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan

2004
Efficacy and duration of action of the four selective angiotensin II subtype 1 receptor blockers, losartan, candesartan, valsartan and telmisartan, in patients with essential hypertension determined by home blood pressure measurements.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2005, Volume: 27, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2005
Novel polymer monolith microextraction using a poly(methacrylic acid-ethylene glycol dimethacrylate) monolith and its application to simultaneous analysis of several angiotensin II receptor antagonists in human urine by capillary zone electrophoresis.
    Journal of chromatography. A, 2006, Jan-13, Volume: 1102, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Electrophoresis, Capillary; Ethylene Glycols; Humans; Irbesartan; Losartan; Methacrylates; Receptors, Angiotensin; Sensitivity and Specificity; Telmisartan; Tetrazoles

2006
Significance of angiotensin II receptor blocker lipophilicities and their protective effect against vascular remodeling.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Body Weight; Carotid Artery Diseases; Gene Expression; Hypertension; Immunohistochemistry; Lipids; Losartan; Male; Membrane Transport Proteins; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type III; Organ Size; Phosphoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Vasodilation

2005
Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation.
    Journal of hypertension, 2006, Volume: 24, Issue:9

    Topics: Adipogenesis; Adiponectin; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Irbesartan; Lipoprotein Lipase; Losartan; Luciferases; Male; Pioglitazone; PPAR gamma; Receptor, Angiotensin, Type 1; RNA, Messenger; Telmisartan; Tetrazoles; Thiazolidinediones

2006
Angiotensin II receptor blockers for the treatment of heart failure: a class effect?
    Pharmacotherapy, 2007, Volume: 27, Issue:4

    Topics: Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; British Columbia; Drug Prescriptions; Female; Heart Failure; Hospital Information Systems; Humans; Irbesartan; Losartan; Male; Ontario; Proportional Hazards Models; Quebec; Retrospective Studies; Survival Analysis; Survival Rate; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Angiotensin AT1 receptor antagonists exert anti-inflammatory effects in spontaneously hypertensive rats.
    British journal of pharmacology, 2007, Volume: 152, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Aorta; Benzimidazoles; Benzoates; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypertension; Losartan; Macrophages; Male; Mice; Monocytes; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, CCR2; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan

2007
Cardiovascular reactivity after blockade of angiotensin AT1 receptors in the experimental model of tilting test in conscious rats.
    British journal of pharmacology, 2008, Volume: 153, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypotension, Orthostatic; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stress, Physiological; Telmisartan

2008
Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Fibrosis; Heart Rate; Hypertension; Hypertrophy; Kidney; Losartan; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium, Dietary; Telmisartan

2008
Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.
    Journal of hypertension, 2008, Volume: 26, Issue:6

    Topics: Adiposity; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Fatty Acids; Losartan; Male; Muscle, Skeletal; Oxidation-Reduction; PPAR gamma; Rats; Rats, Sprague-Dawley; Rats, Wistar; Telmisartan; Weight Gain

2008
Pathological regression by angiotensin II type 1 receptor blockade in patients with mesangial proliferative glomerulonephritis.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:3

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biopsy; Creatinine; Female; Fibrosis; Glomerulonephritis, Membranoproliferative; Humans; Immunoglobulin A; Kidney Glomerulus; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Retrospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation

2008
Renin-angiotensin system blockade is effective in reducing proteinuria of patients with progressive nephropathy caused by MYH9 mutations (Fechtner-Epstein syndrome).
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Cataract; Female; Hearing Loss, Sensorineural; Humans; Kidney Diseases; Losartan; Male; Molecular Motor Proteins; Mutation; Myosin Heavy Chains; Proteinuria; Ramipril; Renin-Angiotensin System; Syndrome; Telmisartan; Thrombocytopenia

2008
Telmisartan prevented cognitive decline partly due to PPAR-gamma activation.
    Biochemical and biophysical research communications, 2008, Oct-24, Volume: 375, Issue:3

    Topics: Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Brain; Cognition Disorders; Losartan; Male; Mice; Mice, Inbred Strains; PPAR gamma; Telmisartan

2008
Aliskiren combined with losartan in diabetes and nephropathy.
    The New England journal of medicine, 2008, Sep-04, Volume: 359, Issue:10

    Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Drug Therapy, Combination; Fumarates; Humans; Losartan; Proteinuria; Renin; Telmisartan

2008
Telmisartan is more effective than losartan in reducing proteinuria.
    Kidney international, 2009, Volume: 75, Issue:1

    Topics: Benzimidazoles; Benzoates; Clinical Trials as Topic; Diabetic Nephropathies; Humans; Losartan; Proteinuria; Telmisartan; Treatment Outcome

2009
Telmisartan and carotid intima-media thickness regression: a class effect of angiotensin-receptor blockers?
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Carotid Arteries; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan

2008
Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model.
    Atherosclerosis, 2009, Volume: 206, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Dietary Fats; Disease Models, Animal; Fatty Liver; Liver; Losartan; Male; Phosphoenolpyruvate Carboxykinase (GTP); Plasminogen Activator Inhibitor 1; PPAR alpha; Rats; Rats, Sprague-Dawley; Telmisartan; Triglycerides

2009
Determination of losartan, telmisartan, and valsartan by direct injection of human urine into a column-switching liquid chromatographic system with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 2009, Sep-08, Volume: 50, Issue:2

    Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Chromatography, High Pressure Liquid; Humans; Losartan; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Telmisartan; Tetrazoles; Valine; Valsartan

2009
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.
    Translational research : the journal of laboratory and clinical medicine, 2009, Volume: 154, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hypertension; Imidazoles; Insulin-Like Growth Factor I; Kidney; Losartan; Male; Myocardium; Nifedipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Sensory Receptor Cells; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2009
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.
    American journal of hypertension, 2009, Volume: 22, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan

2009
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
    Life sciences, 2010, Jan-02, Volume: 86, Issue:1-2

    Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil

2010
Internalization of constitutively active N111G MUTANT of AT1 receptor induced by angiotensin II-receptor antagonists candesartan, losartan, and telmisartan: comparison with valsartan.
    Journal of pharmacological sciences, 2010, Volume: 112, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Losartan; Mutagenesis, Site-Directed; Mutation; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Valine; Valsartan

2010
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.
    Pharmacogenetics and genomics, 2010, Volume: 20, Issue:6

    Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan

2010
Angiotensin AT1 receptor antagonists enhance the anticonvulsant action of valproate in the mouse model of maximal electroshock.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anticonvulsants; Behavior, Animal; Benzimidazoles; Benzoates; Brain; Disease Models, Animal; Drug Synergism; Electroshock; Hypertension; Losartan; Male; Mice; Receptor, Angiotensin, Type 1; Seizures; Telmisartan; Valproic Acid

2010
Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.
    Journal of hypertension, 2010, Volume: 28, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Blood Flow Velocity; Blood Pressure; Cerebral Cortex; Cytokines; Diabetes Mellitus, Experimental; Drug Antagonism; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Losartan; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Superoxides; Telmisartan

2010
Angiotensin receptor type 1 antagonists protect against neuronal injury induced by oxygen-glucose depletion.
    British journal of pharmacology, 2010, Volume: 161, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Death; Coculture Techniques; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glucose; Glutamic Acid; Imidazoles; Losartan; Neurons; Nitric Oxide; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Telmisartan

2010
Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:12

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Echocardiography; Gene Expression; Hemodynamics; Imidazoles; Losartan; Male; Mice; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
The impact of hepatic uptake on the pharmacokinetics of organic anions.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:10

    Topics: Animals; Anions; Benzimidazoles; Benzoates; Bile Ducts; Dogs; Hepatocytes; Humans; Indomethacin; Liver; Losartan; Male; Models, Biological; Muscles; Organic Chemicals; Pharmaceutical Preparations; Protein Binding; Rats; Rats, Sprague-Dawley; Sulfisoxazole; Telmisartan; Tolmetin

2011
The loss of muscle mass and sarcopenia: non hormonal intervention.
    Experimental gerontology, 2011, Volume: 46, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Exercise; Frail Elderly; Heat-Shock Proteins; Humans; Longevity; Losartan; Muscle Strength; Muscular Atrophy; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR delta; Sarcopenia; Telmisartan; TOR Serine-Threonine Kinases; Transcription Factors

2011
Regulation of angiotensin-(1-7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure.
    Acta pharmacologica Sinica, 2011, Volume: 32, Issue:11

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Benzimidazoles; Benzoates; Doxorubicin; Gene Expression Regulation; Heart; Heart Failure; Losartan; Male; Myocardium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Telmisartan

2011
Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Antibodies; Benzimidazoles; Benzoates; Cells, Cultured; Disease Models, Animal; Fibroblasts; Hepatocyte Growth Factor; Hydronephrosis; Kidney; Losartan; Male; Mice; Mice, Knockout; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Transforming Growth Factor beta; Ureteral Obstruction

2012
Effects of angiotensin receptor blockers on endothelial nitric oxide release: the role of eNOS variants.
    British journal of clinical pharmacology, 2012, Volume: 74, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Losartan; Nitric Oxide; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Telmisartan; Tetrazoles; Umbilical Veins; Valine; Valsartan; Vasodilation

2012
Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.
    European journal of pharmacology, 2012, Jun-15, Volume: 685, Issue:1-3

    Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Aorta; Benzimidazoles; Benzoates; Blood Urea Nitrogen; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Losartan; Male; Malondialdehyde; Nephrectomy; PPAR gamma; Rats; Rats, Wistar; Telmisartan; Vasodilation

2012
Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood-Brain Barrier; Blotting, Western; Cognition Disorders; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Losartan; Male; Maze Learning; Mice; Mice, Inbred C57BL; PPAR gamma; Random Allocation; Sensitivity and Specificity; Telmisartan

2012
Analysis of cytotoxicity induced by proinflammatory cytokines in the human alveolar epithelial cell line A549.
    Bioscience trends, 2012, Volume: 6, Issue:2

    Topics: Apoptosis; Benzimidazoles; Benzoates; Catalase; Cell Line; Cytokines; Dexamethasone; Dimethyl Sulfoxide; Doxycycline; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Interferon-gamma; Interleukin-1beta; Losartan; Minocycline; Pulmonary Alveoli; Telmisartan; Tumor Necrosis Factor-alpha

2012
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers.
    Circulation, 2012, Sep-11, Volume: 126, Issue:11 Suppl 1

    Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Collagen; Elastic Tissue; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Genetic Diseases, X-Linked; Heart Defects, Congenital; Humans; Losartan; Mitral Valve Insufficiency; Mitral Valve Prolapse; Myxoma; Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein; Telmisartan; Tetrazoles; Transforming Growth Factor beta; Vimentin

2012
The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 464, Issue:6

    Topics: Action Potentials; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Calcium; Cell Death; Heart; Losartan; Male; Myocardial Infarction; Myocytes, Cardiac; PPAR gamma; Rats; Rats, Sprague-Dawley; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Telmisartan; Voltage-Gated Sodium Channels

2012
Combined treatment with gabapentin and drugs affecting the renin-angiotensin system against electroconvulsions in mice.
    European journal of pharmacology, 2013, Apr-15, Volume: 706, Issue:1-3

    Topics: Amines; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Avoidance Learning; Benzimidazoles; Benzoates; Brain; Captopril; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroshock; Enalapril; Gabapentin; gamma-Aminobutyric Acid; Losartan; Male; Mice; Motor Skills; Seizures; Telmisartan

2013
Pharmacokinetics of angiotensin II receptor blockers in the dog following a single oral administration.
    Drug research, 2013, Volume: 63, Issue:7

    Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Area Under Curve; Benzimidazoles; Benzoates; Chromatography, Liquid; Dogs; Dose-Response Relationship, Drug; Half-Life; Losartan; Male; Models, Biological; Tandem Mass Spectrometry; Telmisartan; Tetrazoles; Tissue Distribution; Valine; Valsartan

2013
Comparative effectiveness of angiotensin-receptor blockers for preventing macrovascular disease in patients with diabetes: a population-based cohort study.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Sep-03, Volume: 185, Issue:12

    Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Irbesartan; Losartan; Male; Myocardial Infarction; Proportional Hazards Models; Retrospective Studies; Stroke; Telmisartan; Tetrazoles; Treatment Outcome

2013
Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Nov-28, Volume: 172, Issue:1

    Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Benzimidazoles; Benzoates; Cell Line, Tumor; Collagen; Female; Humans; Losartan; Lung; Lung Neoplasms; Mice; Nanoparticles; Telmisartan

2013
Comparative effect of angiotensin II type I receptor blockers on serum uric acid in hypertensive patients with type 2 diabetes mellitus: a retrospective observational study.
    Cardiovascular diabetology, 2013, Nov-04, Volume: 12

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Logistic Models; Losartan; Male; Middle Aged; Multivariate Analysis; Olmesartan Medoxomil; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Uric Acid; Valine; Valsartan

2013
Telmisartan protects against vascular dysfunction with peroxisome proliferator-activated receptor-γ activation in hypertensive 5/6 nephrectomized rats.
    Pharmacology, 2013, Volume: 92, Issue:5-6

    Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Aorta; Benzimidazoles; Benzoates; Blood Pressure; Disease Models, Animal; Drug Partial Agonism; Endothelium, Vascular; Hypertension; Losartan; Male; Nitric Oxide Synthase Type III; PPAR gamma; Rats; Rats, Wistar; Telmisartan; Vasodilation

2013
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2014
Differential effects of angiotensin II receptor blockers on Aβ generation.
    Neuroscience letters, 2014, May-01, Volume: 567

    Topics: Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Fibroblasts; Imidazoles; Losartan; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Tetrazoles; Valine; Valsartan

2014
Effect of dietary fiber on the level of free angiotensin II receptor blocker in vitro.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Dietary Fiber; Electrolytes; Hydrogen-Ion Concentration; Losartan; Sodium Chloride; Telmisartan; Tetrazoles

2014
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements.
    Journal of hypertension, 2016, Volume: 34, Issue:6

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan

2016
The effect of the angiotensin II receptor, type 1 receptor antagonists, losartan and telmisartan, on thioacetamide-induced liver fibrosis in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antioxidants; Aryldialkylphosphatase; Aspartate Aminotransferases; Benzimidazoles; Benzoates; Cytokines; Glutathione; Glutathione Disulfide; Liver; Liver Cirrhosis; Losartan; Male; Rats, Wistar; Telmisartan; Thioacetamide

2016
Differential effects of angiotensin receptor blockers on pancreatic islet remodelling and glucose homeostasis in diet-induced obese mice.
    Molecular and cellular endocrinology, 2017, 01-05, Volume: 439

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Weight; Carbohydrate Metabolism; Diet, High-Fat; Energy Intake; Fasting; Feeding Behavior; Fluorescent Antibody Technique; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Homeostasis; Islets of Langerhans; Losartan; Male; Mice, Inbred C57BL; Mice, Obese; Telmisartan

2017
Effects of telmisartan and losartan on irradiated testes.
    Life sciences, 2018, Feb-01, Volume: 194

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Losartan; Male; Radiation-Protective Agents; Rats, Wistar; Spermatogenesis; Spermatozoa; Telmisartan; Testis

2018
Brain Renin-Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2018, Volume: 15, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Line, Tumor; Corpus Striatum; Humans; Hyperkinesis; Losartan; Male; Methamphetamine; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptors, Dopamine D3; Renin-Angiotensin System; Telmisartan; Up-Regulation

2018
Influence of the AT1 Receptor Antagonists Telmisartan and Losartan on Reproduction and Offspring After Paternal Exposure to Ionizing Radiation.
    Reproductive sciences (Thousand Oaks, Calif.), 2019, Volume: 26, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Female; Fetal Viability; Losartan; Male; Paternal Exposure; Pregnancy; Pregnancy Rate; Radiation Exposure; Radiation, Ionizing; Rats, Wistar; Reproduction; Telmisartan

2019
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan

2019
Effect of angiotensin II blockers on the prognosis of COVID-19: a toxicological view.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020, Volume: 39, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Host-Pathogen Interactions; Humans; Losartan; Pandemics; Pneumonia, Viral; Prognosis; SARS-CoV-2; Severity of Illness Index; Telmisartan; Tomography, X-Ray Computed; Valsartan

2020
Angiotensin II type 1 receptor blocker telmisartan inhibits the development of transient hypoxia and improves tumour response to radiation.
    Cancer letters, 2020, 11-28, Volume: 493

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cancer-Associated Fibroblasts; Cell Line, Tumor; Collagen Type I; Fluorescent Dyes; Humans; Losartan; Mice; Neoplasms; Pentoxifylline; Positron-Emission Tomography; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy; Telmisartan; Tumor Hypoxia; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Mechanisms Involved in Superiority of Angiotensin Receptor Blockade over ACE Inhibition in Attenuating Neuropathic Pain Induced in Rats.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Losartan; Male; Neuralgia; Oxidative Stress; Pain Measurement; Rats; Renin-Angiotensin System; Sciatic Neuropathy; Telmisartan

2020
Angiotensin-converting enzyme inhibitors, angiotensin-II-receptor antagonists and angiotensin-receptor blocker/neprilysin inhibitor utilization in heart failure patients: Sub-analysis of a nation-wide population-based study in the Czech Republic.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2022, Volume: 166, Issue:3

    Topics: Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Czech Republic; Heart Failure; Humans; Losartan; Neprilysin; Perindopril; Ramipril; Retrospective Studies; Telmisartan; Valsartan

2022
Investigation of Carcinogenic Impurities of N-Nitrosamines in Sartan Pharmaceutical Products Marketed in Brazil: Development and Validation of Method Based on High-Performance Liquid Chromatography-Tandem Mass Spectrometry.
    Journal of pharmaceutical sciences, 2023, Volume: 112, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Brazil; Carcinogens; Chromatography, High Pressure Liquid; Humans; Irbesartan; Losartan; Nitrosamines; Pharmaceutical Preparations; Tandem Mass Spectrometry; Telmisartan; Valsartan

2023
Telmisartan and losartan: The marked differences between their chemical and pharmacological properties may explain the difference in therapeutic efficacy in hospitalized patients with COVID-19.
    Pharmacology research & perspectives, 2023, Volume: 11, Issue:2

    Topics: Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; Telmisartan

2023
Telmisartan Is a Promising Agent for Managing Neuropathic Pain and Delaying Opioid Analgesic Tolerance in Rats.
    International journal of molecular sciences, 2023, Apr-27, Volume: 24, Issue:9

    Topics: Analgesics; Analgesics, Opioid; Animals; Drug Tolerance; Glutamates; Guanosine 5'-O-(3-Thiotriphosphate); Losartan; Morphine; Neuralgia; Rats; Telmisartan

2023
Risk of myocardial infarction, heart failure, and cerebrovascular disease with the use of valsartan, losartan, irbesartan, and telmisartan in patients.
    Medicine, 2023, Nov-17, Volume: 102, Issue:46

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cerebrovascular Disorders; Heart Failure; Humans; Irbesartan; Losartan; Myocardial Infarction; Retrospective Studies; Telmisartan; Tetrazoles; Valsartan

2023
An Emerging Strategy for Neuroinflammation Treatment: Combined Cannabidiol and Angiotensin Receptor Blockers Treatments Effectively Inhibit Glial Nitric Oxide Release.
    International journal of molecular sciences, 2023, Nov-13, Volume: 24, Issue:22

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cannabidiol; Humans; Lipopolysaccharides; Losartan; Neuroglia; Neuroinflammatory Diseases; Nitric Oxide; Telmisartan; Tumor Necrosis Factor-alpha

2023