Compounds > losartan

losartan and sirolimus

losartan has been researched along with sirolimus in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's6 (46.15)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Giasson, E; Meloche, S1
Ouali, N1
Bennett, T; Fallgren, B; Gardiner, SM; Kemp, PA; March, JE1
Robin, NH1
Bieri, M; Farkas, A; Ligeti, N; Marti, HP; Meier, B; Mohacsi, P; Oroszlán, M1
Brailoiu, E; Brailoiu, GC; Deliu, E; Motoc, D; Tica, AA1
Chen, G; Dong, QR; Li, MX; Li, XM1
Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M1

Reviews

4 review(s) available for losartan and sirolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
Treatment for genetic diseases.
    Current opinion in pediatrics, 2008, Volume: 20, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Fragile X Syndrome; Genetic Diseases, Inborn; Genetic Predisposition to Disease; Genetic Research; Humans; Immunosuppressive Agents; Losartan; Marfan Syndrome; Mice; Neurofibromatoses; Sirolimus

2008
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin

2020

Other Studies

9 other study(ies) available for losartan and sirolimus

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine

1995
[Complications in kidney transplantation].
    Presse medicale (Paris, France : 1983), 2001, Sep-01, Volume: 30, Issue:24 Pt 2

    Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus; Graft Rejection; Humans; Hyperlipidemias; Immunosuppressive Agents; Kidney Transplantation; Losartan; Myocardial Infarction; Proteinuria; Risk Factors; Sirolimus

2001
Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cyclosporine; Drug Interactions; Heart Rate; Hemodynamics; Immunosuppressive Agents; Indans; Infusions, Intravenous; Losartan; Male; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sirolimus; Tacrolimus

2004
Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.
    Transplant immunology, 2010, Volume: 23, Issue:3

    Topics: Albumins; Angiotensin II; Cell Line; Down-Regulation; Drug Therapy, Combination; Endocytosis; Epithelial Cells; Everolimus; Humans; Immunosuppressive Agents; Kidney Tubules, Proximal; Losartan; Low Density Lipoprotein Receptor-Related Protein-2; Ramipril; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Signal Transduction; Sirolimus

2010
Intracellular angiotensin II activates rat myometrium.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arsenicals; Autophagy; Brefeldin A; Calcium Signaling; Carbolines; Cells, Cultured; Egtazic Acid; Endocytosis; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Estrenes; Female; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Lysosomes; Macrocyclic Compounds; Macrolides; Models, Biological; Myometrium; NADP; Oxazoles; Piperazines; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ryanodine; Saralasin; Signal Transduction; Sirolimus; Type C Phospholipases; Uterus

2011
[The 467th case: proteinuria, periungual fibromas, and facial steatadenomas].
    Zhonghua nei ke za zhi, 2019, Jan-01, Volume: 58, Issue:1

    Topics: Angiomyolipoma; Apolipoprotein L1; Creatinine; Female; Glomerulonephritis, IGA; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Losartan; Male; Mutation; Nephrotic Syndrome; Proteinuria; Sirolimus; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Young Adult

2019