losartan and propranolol

losartan has been researched along with propranolol in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (20.97)	18.2507
2000's	20 (32.26)	29.6817
2010's	26 (41.94)	24.3611
2020's	3 (4.84)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Fregly, MJ; Rowland, NE	1
Pfaffendorf, M; van Zwieten, PA; Zhang, J	2
Cano, C; Malik, KU; Slavik, KJ	1
Crespo, MJ; De Mello, WC	1
Couch, SJ; Pals, DT	1
Cade, JR; Fregly, MJ; Rowland, NE	1
Brecher, P; Chobanian, AV; Du, Y; Gavras, H; Makaritsis, KP	1
Angus, JA; Whorlow, SL; Wright, CE	1
Chan, P; Chen, YJ; Cheng, JT; Liu, JC; Tomlinson, B; Tong, YC; Wang, CC	1
Acevedo, E; Ebensperger, R; Gálvez, A; González-Jara, F; Jalil, JE; Lavandero, S; Meléndez, J; Pérez-Montes, V; Sapag-Hagar, M	1
Dam, TV; deBlois, D; Hamet, P; Moreau, P; Tea, BS	1
Hashimoto, Y; Narita, H; Yabana, H	1
Cao, H; Kariv, I; Oldenburg, KR	1
Kato, H; Kurihara, J; Matsuoka, Y; Okubo, Y; Suzuki, S; Takata, Y; Yoda, T	1
Esposito, G; Fox, JE; Hagaman, JR; Knowles, JW; Maeda, N; Mao, L; Rockman, HA; Smithies, O	1
Albillos, A; Bañares, R; Bosch, J; Del Arbol, LR; Escorsell, A; García-Pagán, JC; González, M; González-Abraldes, J; Moitinho, E; Rodríguez, C	1
Bernardo, F; Castaño, G; Frider, B; Gustavo, C; Pedro, V; Silvia, S; Sookoian, S; Viudez, P	1
Blendis, L; Lurie, Y; Oren, R	1
Blendis, LM; Wong, F	1
Bandyopadhyay, K; Biswas, PK; Das, D; Das, TK; Dasgupta, S; De, BK; Majumdar, D; Mandal, SK; Ray, S	1
Bennett, T; Fallgren, B; Gardiner, SM; Kemp, PA; March, JE	1
Dendorfer, A; Dominiak, P; Raasch, W; Ziegler, A	1
Bennett, T; Gardiner, SM; Kemp, PA; March, JE	1
Anyukhovsky, EP; Danilo, P; Hefer, D; Janse, MJ; Rosen, MR; Rosen, TS; Sosunov, EA	1
Adam, M	1
Balestri, G; Castiglioni, P; Centola, M; Cesana, F; Di Rienzo, M; Ferrari, AU; Radaelli, A	1
Bedja, D; Calvi, C; Carta, L; Cohn, RD; Cooper, TK; Dietz, HC; Gabrielson, K; Habashi, JP; Halushka, MK; Holm, TM; Huso, DL; Judge, DP; Klein, EC; Liu, G; Loeys, BL; Myers, L; Neptune, ER; Podowski, M; Ramirez, F; Rifkin, DB	1
Inamdar, MN; Kumar, NP; Venkataraman, BV	1
Hu, X; Shi, Y; Wei, EQ; Xu, M; Zhang, JF; Zhang, YM	1
Shi, J; Tian, M; Xie, W; Zhu, D	1
Chmielinska, JJ; Landgraf, KM; Mak, IT; Weglicki, WB	1
Agasti, AK; Mahajan, AU; Nathani, PJ; Phadke, AY; Sawant, P	1
Chen, CA; Chiu, HH; Chiu, SN; Hu, FC; Lin, MT; Lu, CW; Wang, JK; Wu, MH	1
Elshershari, H; Harris, C	1
Estato, V; Freitas, F; Lessa, MA; Tibiriçá, E	1
Godoy, AA; Kummrow, F; Pamplin, PA	1
Broekelmann, TJ; Halabi, CM; Knutsen, RH; Kozel, BA; Mecham, RP; Ye, L	1
Buchneva, NV; Kuzmin, OB; Landar, LN	1
Carter, JJ; Fretwell, LV; Woolard, J	1
de Araújo, JE; de Paula Facioli, T; de Souza, HC; Gastaldi, AC; Maida, KD	1
Chen, MR; Lin, DS; Lin, SM; Liu, LH	1
Mandorfer, M; Mueller, S; Ozga, AK; Peccerella, T; Piecha, F; Poth, T; Rausch, V; Reiberger, T; Seitz, HK; Vonbank, A	1
de Moura Leão, MF; de Oliveira, LFS; Duarte, JA; Machado, MM; Piccoli, JDCE; Sauzen, PD	1
Flores-Monroy, J; Fonseca-Coronado, S; Hernandez-Campos, ME; Lezama-Martinez, D; Martinez-Aguilar, L; Valencia-Hernandez, I	1
Borges, DR; de Araújo, LJT; Kouyoumdjian, M; Nagaoka, MR	1
Eagle, KA; Hofmann Bowman, MA; Milewicz, DM	1
Gatineau, E; Gong, MC; Yiannikouris, F	1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM	1
Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ	1

Reviews

3 review(s) available for losartan and propranolol

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Update on Clinical Trials of Losartan With and Without β-Blockers to Block Aneurysm Growth in Patients With Marfan Syndrome: A Review. JAMA cardiology, 2019, 07-01, Volume: 4, Issue:7 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm, Thoracic; Clinical Trials as Topic; Disease Models, Animal; Humans; Losartan; Marfan Syndrome; Mice; Propranolol; Treatment Outcome	2019

Trials

4 trial(s) available for losartan and propranolol

Article	Year
Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis. Gastroenterology, 2001, Volume: 121, Issue:2 Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Losartan; Male; Middle Aged; Propranolol; Splanchnic Circulation	2001
Portal pressure response to losartan compared with propranolol in patients with cirrhosis. The American journal of gastroenterology, 2003, Volume: 98, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Male; Middle Aged; Portal Vein; Propranolol	2003
Comparative randomized study on efficacy of losartan versus propranolol in lowering portal pressure in decompensated chronic liver disease. Journal of digestive diseases, 2013, Volume: 14, Issue:5 Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Male; Middle Aged; Portal Pressure; Propranolol; Treatment Outcome	2013
Losartan added to β-blockade therapy for aortic root dilation in Marfan syndrome: a randomized, open-label pilot study. Mayo Clinic proceedings, 2013, Volume: 88, Issue:3 Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Aortic Diseases; Atenolol; Child; Dilatation, Pathologic; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Losartan; Male; Marfan Syndrome; Pilot Projects; Propranolol; Treatment Outcome; Young Adult	2013

Other Studies

55 other study(ies) available for losartan and propranolol

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Effect of DuP 753, a nonpeptide angiotensin II receptor antagonist, on the drinking responses to acutely administered dipsogenic agents in rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 199, Issue:2 Topics: 5-Hydroxytryptophan; Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Losartan; Male; Polyethylene Glycols; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Saline Solution, Hypertonic; Serotonin; Tetrazoles	1992
Effect of various angiotensin receptor antagonists on cardiovascular responses to angiotensin II in pithed rats. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles	1994
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC. The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2 Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles	1995
Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:5 Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rabbits; Tetrazoles; Ventricular Function, Left	1995
Cardiac refractoriness in rats is reduced by angiotensin II. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1 Topics: Action Potentials; Angiotensin II; Animals; Biphenyl Compounds; Drug Interactions; Electrophysiology; Heart Ventricles; Imidazoles; In Vitro Techniques; Losartan; Male; Membrane Potentials; Muscle, Smooth, Vascular; Phentolamine; Propranolol; Rats; Tetrazoles	1995
Renin release induced by losartan (DuP 753), an angiotensin II receptor antagonist. Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:1 Topics: Angiotensin Receptor Antagonists; Animals; Atenolol; Biphenyl Compounds; Dose-Response Relationship, Drug; Feedback; Imidazoles; Indomethacin; Injections, Intravenous; Losartan; Male; Meclofenamic Acid; Propranolol; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin; Sympathetic Nervous System; Tetrazoles	1993
Relationship between drinking and increase in tail skin temperature of rats treated with L-5-hydroxytryptophan. Pharmacology, 1996, Volume: 52, Issue:2 Topics: 5-Hydroxytryptophan; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Basal Metabolism; Biphenyl Compounds; Body Temperature Regulation; Drinking; Imidazoles; Isoproterenol; Losartan; Male; Oxygen Consumption; Propranolol; Rats; Rats, Sprague-Dawley; Skin Temperature; Tail; Tetrazoles	1996
Alpha1-adrenergic plus angiotensin receptor blockade reduces atherosclerosis in apolipoprotein E-deficient mice. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:6 Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Drug Therapy, Combination; Hypercholesterolemia; Losartan; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Prazosin; Propranolol; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors	1998
Endogenous angiotensin II and bradykinin delay and attenuate the hypotension after N-type calcium channel blockade in conscious rabbits. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradykinin; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hypotension; Losartan; Nasopharynx; omega-Conotoxin GVIA; Peptides; Pressoreceptors; Propranolol; Rabbits; Renin-Angiotensin System	1998
Effects of losartan on the sexual behavior of male rats. Pharmacology, 1999, Volume: 58, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Ejaculation; Female; Losartan; Male; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sexual Behavior, Animal	1999
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat. Life sciences, 1999, Volume: 64, Issue:18 Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hypertrophy, Left Ventricular; Insulin-Like Growth Factor I; Losartan; Male; Methyldopa; Myocardium; Propranolol; Radioimmunoassay; Rats; Rats, Sprague-Dawley	1999
Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Calcium Channel Blockers; Cardiomegaly; Data Interpretation, Statistical; DNA; DNA Fragmentation; Enalapril; Hemodynamics; Hydralazine; Losartan; Male; Nifedipine; Propranolol; Rats; Time Factors	1999
Diverse effects of AT1 receptor antagonists on normal blood pressure and regulatory system. Hypertension research : official journal of the Japanese Society of Hypertension, 1999, Volume: 22, Issue:2 Topics: Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Pressoreceptors; Propranolol; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Glutamate; Reflex; Tetrazoles	1999
Development of a high throughput equilibrium dialysis method. Journal of pharmaceutical sciences, 2001, Volume: 90, Issue:5 Topics: Antidepressive Agents; Antihypertensive Agents; Blood Proteins; Dialysis; Drug Evaluation, Preclinical; Humans; Losartan; Male; Paroxetine; Propranolol; Protein Binding; Ultrafiltration	2001
KT3-671, an angiotensin AT1 receptor antagonist, attenuates vascular but not cardiac responses to sympathetic nerve stimulation in pithed rats. Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:4 Topics: Adrenalectomy; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Decerebrate State; Electric Stimulation; Guanethidine; Heart Rate; Imidazoles; Losartan; Male; Norepinephrine; Propranolol; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spinal Cord; Sympathetic Nervous System; Sympathomimetics; Tetrazoles	2001
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of clinical investigation, 2001, Volume: 107, Issue:8 Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Enalapril; Furosemide; Guanylate Cyclase; Hydralazine; Losartan; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; Organ Size; Propranolol; Receptors, Atrial Natriuretic Factor; Telemetry; Ventricular Dysfunction, Left	2001
Discussion on randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis. Gastroenterology, 2002, Volume: 122, Issue:5 Topics: Antihypertensive Agents; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Male; Propranolol; Randomized Controlled Trials as Topic	2002
"A la carte" treatment of portal hypertension or just "hors d'oeuvres". Gastroenterology, 2003, Volume: 124, Issue:7 Topics: Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Losartan; Prazosin; Propranolol	2003
Does losartan work after all? The American journal of gastroenterology, 2003, Volume: 98, Issue:6 Topics: Antihypertensive Agents; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Propranolol; Randomized Controlled Trials as Topic	2003
Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats. British journal of pharmacology, 2004, Volume: 141, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cyclosporine; Drug Interactions; Heart Rate; Hemodynamics; Immunosuppressive Agents; Indans; Infusions, Intravenous; Losartan; Male; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sirolimus; Tacrolimus	2004
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 44, Issue:3 Topics: Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desipramine; Diastole; Dose-Response Relationship, Drug; Losartan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Sympathectomy, Chemical; Sympathetic Nervous System; Symporters; Tetrazoles; Tubocurarine; Yohimbine	2004
Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response. British journal of pharmacology, 2004, Volume: 143, Issue:3 Topics: Amidines; Animals; Arginine; Arginine Vasopressin; Benzylamines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Consciousness; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Indans; Indomethacin; Injections, Intravenous; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Propranolol; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Urotensins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2004
Region-specific, pacing-induced changes in repolarization in rabbit atrium: an example of sensitivity to the rare. Cardiovascular research, 2005, Aug-01, Volume: 67, Issue:2 Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Apamin; Atrial Fibrillation; Atropine; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiac Pacing, Artificial; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Atria; Heart Conduction System; Losartan; Nifedipine; Potassium Channel Blockers; Propranolol; Pulmonary Veins; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Muscarinic; Ryanodine	2005
Integrating research and development: the emergence of rational drug design in the pharmaceutical industry. Studies in history and philosophy of biological and biomedical sciences, 2005, Volume: 36, Issue:3 Topics: Biomedical Research; Captopril; Drug Design; Drug Industry; Germany; Humans; Losartan; Propranolol; United States	2005
Adrenergic origin of very low-frequency blood pressure oscillations in the unanesthetized rat. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1 Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Arginine Vasopressin; Barium Sulfate; Blood Pressure; Calcium Channel Blockers; Consciousness; Epinephrine; Ganglionic Blockers; Hemodynamics; Hexamethonium; Losartan; Nifedipine; Norepinephrine; Potassium Channel Blockers; Prazosin; Propranolol; Rats; Rats, Inbred WKY; Receptors, Adrenergic; Vasoconstrictor Agents; Yohimbine	2006
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science (New York, N.Y.), 2006, Apr-07, Volume: 312, Issue:5770 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Aorta; Aortic Aneurysm; Disease Models, Animal; Elastic Tissue; Female; Fibrillin-1; Fibrillins; Losartan; Lung; Lung Diseases; Marfan Syndrome; Mice; Microfilament Proteins; Mutation; Neutralization Tests; Pregnancy; Pregnancy Complications; Propranolol; Pulmonary Alveoli; Receptor, Angiotensin, Type 1; Signal Transduction; Transforming Growth Factor beta	2006
Comparative interaction of few antihypertensive drugs with cyclosporine-A in rats. Indian journal of experimental biology, 2007, Volume: 45, Issue:7 Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta, Thoracic; Chromatography, High Pressure Liquid; Cyclosporine; Diltiazem; Drug Interactions; Enalapril; Losartan; Male; Olive Oil; Plant Oils; Propranolol; Rats; Rats, Wistar	2007
Administration of angiotensin II in the paraventricular nucleus protects gastric mucosa from ischemia-reperfusion injury. Brain research, 2008, May-30, Volume: 1212 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Losartan; Male; Paraventricular Hypothalamic Nucleus; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathectomy; Time Factors; Vasoconstrictor Agents	2008
Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains. FEBS letters, 2012, Oct-19, Volume: 586, Issue:20 Topics: Alzheimer Disease; Angiotensin II; Animals; Brain; Cognition; Dose-Response Relationship, Drug; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Indoles; Losartan; Male; Maleimides; Phosphorylation; Propranolol; Rats; Rats, Sprague-Dawley; Signal Transduction; tau Proteins	2012
Angiotensin II promotes iron accumulation and depresses PGI₂ and NO synthesis in endothelial cells: effects of losartan and propranolol analogs. Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:10 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cattle; Cell Survival; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Epoprostenol; Glutathione; Iron; Iron Overload; Losartan; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Propranolol; Receptor, Angiotensin, Type 1	2012
Paternal fibrillin-1 mutation transmitted to an affected son with neonatal marfan syndrome: the importance of early recognition. Cardiology in the young, 2014, Volume: 24, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Aorta; Dilatation, Pathologic; Disease Progression; Early Diagnosis; Early Medical Intervention; Echocardiography; Fathers; Fibrillin-1; Fibrillins; Humans; Infant, Newborn; Losartan; Male; Marfan Syndrome; Microfilament Proteins; Mutation; Propranolol	2014
Cardiac microvascular rarefaction in hyperthyroid rats is reversed by losartan, diltiazem, and propranolol. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Diltiazem; Hyperthyroidism; Hypertrophy, Left Ventricular; Losartan; Male; Microcirculation; Myocardium; Propranolol; Rats; Rats, Wistar; Ventricular Function, Left	2015
Ecotoxicological evaluation of propranolol hydrochloride and losartan potassium to Lemna minor L. (1753) individually and in binary mixtures. Ecotoxicology (London, England), 2015, Volume: 24, Issue:5 Topics: Antihypertensive Agents; Araceae; Ecotoxicology; Environmental Monitoring; Losartan; Propranolol; Risk Assessment; Water Pollutants, Chemical; Water Quality	2015
Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness. American journal of physiology. Heart and circulatory physiology, 2015, Volume: 309, Issue:5 Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Elastin; Losartan; Mice; Mice, Inbred C57BL; Nicardipine; Propranolol; Vascular Stiffness; Williams Syndrome	2015
[INTERACTION OF BETA-BLOCKER PROPRANOLOL WITH RENIN-ANGIOTENSIN SYSTEM INHIBITORS IN RAT KIDNEY]. Eksperimental'naia i klinicheskaia farmakologiia, 2016, Volume: 79, Issue:3 Topics: Amides; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diuresis; Diuretics; Drug Synergism; Enalapril; Fumarates; Kidney; Losartan; Male; Natriuresis; Potassium; Propranolol; Rats; Renin-Angiotensin System; Sodium	2016
Effects of 4 multitargeted receptor tyrosine kinase inhibitors on regional hemodynamics in conscious, freely moving rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:3 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Consciousness; Hemodynamics; Indazoles; Losartan; Male; Niacinamide; Phenylurea Compounds; Piperidines; Propranolol; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Regional Blood Flow; Sorafenib; Sulfonamides	2017
Physical training associated with Enalapril but not to Losartan, results in better cardiovascular autonomic effects. Autonomic neuroscience : basic & clinical, 2017, Volume: 203 Topics: Animals; Antihypertensive Agents; Atropine; Autonomic Nervous System; Baroreflex; Blood Pressure; Combined Modality Therapy; Disease Models, Animal; Enalapril; Exercise Therapy; Heart Rate; Hypertension; Losartan; Male; Parasympatholytics; Propranolol; Rats, Inbred SHR; Sedentary Behavior; Swimming	2017
Losartan in combination with propranolol slows the aortic root dilatation in neonatal Marfan syndrome. Pediatrics and neonatology, 2018, Volume: 59, Issue:2 Topics: Drug Therapy, Combination; Fibrillin-1; Humans; Infant, Newborn; Losartan; Male; Marfan Syndrome; Mutation; Propranolol; Vasodilation	2018
Pharmacological decrease of liver stiffness is pressure-related and predicts long-term clinical outcome. American journal of physiology. Gastrointestinal and liver physiology, 2018, 10-01, Volume: 315, Issue:4 Topics: Adult; Aged; Animals; Antihypertensive Agents; Arterial Pressure; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Circulation; Liver Cirrhosis; Losartan; Male; Middle Aged; Nitric Oxide; Portal Pressure; Propranolol; Rats; Rats, Wistar	2018
Cytotoxic and genotoxic effects of antihypertensives distributed in Brazil by social programs: Are they safe? Environmental toxicology and pharmacology, 2018, Volume: 63 Topics: Antihypertensive Agents; Atenolol; Brazil; Captopril; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Enalapril; Government Programs; Humans; Hydrochlorothiazide; Hypertension; Losartan; Lymphocytes; Macrophages; Male; Mutagenicity Tests; Program Evaluation; Propranolol	2018
Combined Antihypertensive Therapies That Increase Expression of Cardioprotective Biomarkers Associated With the Renin-Angiotensin and Kallikrein-Kinin Systems. Journal of cardiovascular pharmacology, 2018, Volume: 72, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Kallikrein-Kinin System; Losartan; Male; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Renin-Angiotensin System; RNA, Messenger	2018
Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Nov-14, Volume: 51, Issue:12 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Glucose; Hemodynamics; Hypertension, Portal; Liver; Losartan; Male; Prazosin; Propranolol; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors	2018
Soluble Prorenin Receptor Increases Blood Pressure in High Fat-Fed Male Mice. Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Baroreflex; Blood Pressure; Chlorisondamine; Diet, High-Fat; Ganglionic Blockers; Infusions, Subcutaneous; Leptin; Losartan; Male; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Propranolol; Prorenin Receptor; Receptors, Cell Surface	2019
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146 Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan	2020
Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. Cancer research communications, 2022, Volume: 2, Issue:12 Topics: Animals; Brain Neoplasms; Cancer Vaccines; Dogs; Glioma; Losartan; Propranolol; Prospective Studies; Tumor Microenvironment; Vaccination	2022