losartan has been researched along with prazosin in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (39.29) | 18.2507 |
| 2000's | 19 (33.93) | 29.6817 |
| 2010's | 14 (25.00) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Chauhan, BS; Gandhi, HP; Giridhar, R; Naik, PP; Yadav, MR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Timmermans, PB; Wong, PC | 1 |
| Lupichuk, SM; Tabrizchi, R | 1 |
| Ichihara, A; Matsumoto, A; Murakami, M; Naitoh, M; Saruta, T; Suzuki, H | 1 |
| Tabrizchi, R | 1 |
| Hajj-Ali, AF; Reilly, TM; Wong, PC | 1 |
| Baylis, C; Engels, K; Qiu, C | 1 |
| Brecher, P; Chobanian, AV; Crawford, DC; Himeno, H; Hosoi, M | 1 |
| Endoh, M; Ishihata, A | 1 |
| Blanc, J; Elghozi, JL; Gaudet, E | 1 |
| Alonso-Galicia, M; Brands, MW; Hall, JE; Zappe, DH | 1 |
| Baujard, C; Elghozi, JL; Ponchon, P | 1 |
| Elghozi, JL; Ponchon, P | 2 |
| Dumont, CJ; Grekin, RJ; Vollmer, AP; Watts, SW; Webb, RC | 1 |
| Kadekaro, M; Liu, H; Summy-Long, JY; Terrell, ML | 1 |
| Irlbeck, M; Iwai, T; Zimmer, HG | 1 |
| Endoh, M; Watanabe, A | 1 |
| Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ | 1 |
| Brecher, P; Chobanian, AV; Du, Y; Gavras, H; Makaritsis, KP | 1 |
| Baylis, C; Engels, K; Harvey, J; Santmyire, BR | 1 |
| Li, J; Wang, DH | 1 |
| Blanc, J; Elghozi, JL; Jover, B; Laude, D; Ponchon, P | 1 |
| Beresewicz, A; Maczewski, M | 1 |
| Crespo, MJ | 1 |
| Elghozi, JL; Girard, A; Holand, S; Laude, D | 1 |
| Eriksson, S; Rundgren, M; Ullman, J | 2 |
| Blumberg, MS; Kirby, RF; Knoot, TG | 1 |
| Corrêa, FM; Peres-Polon, VL; Tavares, RF | 1 |
| de Godoy, MA; de Oliveira, AM | 1 |
| Berg, T | 1 |
| Blendis, L; Lurie, Y; Oren, R | 1 |
| de Arruda Camargo, LA; de Souza Villa, P; Saad, WA | 1 |
| Fazan, R; Joaquim, LF; Oliveira, RP; Salgado, HC; Salgado, MC | 1 |
| Balestri, G; Castiglioni, P; Centola, M; Cesana, F; Di Rienzo, M; Ferrari, AU; Radaelli, A | 1 |
| Greene, AS; Petersen, MC | 1 |
| Buzuyeva, II; Filyushina, EE; Lazarev, VA; Markel', AL; Shmerling, MD; Yakobson, GS | 1 |
| Gandhi, HP; Giridhar, R; Naik, PP; Yadav, MR | 1 |
| Cardoso, LM; Chianca, DA; da Silva, LG; de Menezes, RC; Fernandes, LG; Ferreira, AJ; Foureaux, G; Gomide, JM; Lima, MP; Miranda, PH; Pesquero, JL; Silva, FC | 1 |
| Buzueva, II; Filyushina, EE; Lazarev, VA; Merkel, AL; Shmerling, MD; Yakobson, GS | 1 |
| Cacanyiova, S; Kristek, F; Malekova, M | 1 |
| Chen, L; Wang, Y; Wier, WG; Zhang, J | 1 |
| Agrawal, N; Gandhi, H; Naik, P; Yadav, M | 1 |
| Borges, DR; de Araújo, LJT; Kouyoumdjian, M; Nagaoka, MR | 1 |
| Bu, X; Hao, B; Ma, C; Ma, H; Tian, Y; Wu, J; Zhao, B; Zhu, L | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
1 review(s) available for losartan and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
55 other study(ies) available for losartan and prazosin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
Design and synthesis of 6,7-dimethoxyquinazoline analogs as multi-targeted ligands for α1- and AII-receptors antagonism.
Topics: Animals; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Angiotensin; Structure-Activity Relationship | 2013 |
Nonpeptide angiotensin II receptor antagonists: insurmountable angiotensin II antagonism of EXP3892 is reversed by the surmountable antagonist DuP 753.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Drug Interactions; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Pressoreceptors; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1991 |
The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Decerebrate State; Dose-Response Relationship, Drug; Imidazoles; Infusions, Intra-Arterial; Infusions, Intravenous; Losartan; Male; Nifedipine; Prazosin; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction; Vasodilator Agents | 1995 |
Interactions between angiotensin II and norepinephrine on renin release by juxtaglomerular cells.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Antibody Technique; Fura-2; Image Processing, Computer-Assisted; Imidazoles; Juxtaglomerular Apparatus; Losartan; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Vasoconstrictor Agents | 1995 |
Influence of nonpeptide angiotensin II receptor antagonist, losartan, on neurogenic vasoconstriction.
Topics: Adenosine Triphosphate; Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Prazosin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Vasoconstriction; Yohimbine | 1995 |
Modulation of renal vasoconstrictor effect of NG-nitro-L-arginine in rabbit by angiotensin II and alpha-1 adrenergic receptor blockade.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antibodies; Arginine; Biphenyl Compounds; Drug Interactions; Hemodynamics; Hydralazine; Imidazoles; Kidney; Losartan; Male; Nitroarginine; Prazosin; Rabbits; Tetrazoles; Vasoconstrictor Agents | 1994 |
Angiotensin II and alpha 1-adrenergic tone in chronic nitric oxide blockade-induced hypertension.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Glomerular Filtration Rate; Hematocrit; Hypertension; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Angiotensin; Reference Values; Regional Blood Flow; Renal Circulation; Tetrazoles; Vascular Resistance | 1994 |
Angiotensin II alters aortic fibronectin independently of hypertension.
Topics: Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Fibronectins; Humans; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Prazosin; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles | 1994 |
Pharmacological characteristics of the positive inotropic effect of angiotensin II in the rabbit ventricular myocardium.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bupranolol; Heart Ventricles; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Prazosin; Pyridines; Rabbits; Saralasin; Tetrazoles | 1993 |
Role of angiotensin II and catecholamines in blood pressure variability responses to stress in SHR.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Heart Rate; Imidazoles; Losartan; Male; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stress, Physiological; Tetrazoles | 1996 |
Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Hemodynamics; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Male; Obesity; Prazosin; Rats; Rats, Zucker; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Tetrazoles | 1996 |
Effects of graded hemorrhage on short-term variability of blood pressure in conscious rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Gas Analysis; Blood Pressure; Blood Proteins; Heart Rate; Hemorrhage; Imidazoles; Losartan; Male; Prazosin; Rats; Rats, Wistar; Respiration; Signal Processing, Computer-Assisted; Sympatholytics; Tetrazoles | 1996 |
Contribution of humoral systems to the short-term variability of blood pressure after severe hemorrhage.
Topics: Animals; Antihypertensive Agents; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Carbon Dioxide; Consciousness; Diastole; Heart Rate; Hemorrhage; Hormone Antagonists; Imidazoles; Losartan; Male; Oxygen; Prazosin; Rats; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Systole; Tetrazoles; Time Factors | 1997 |
Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion.
Topics: Acetylcholine; Aldosterone; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Corticosterone; Epinephrine; Fatty Acids, Nonesterified; Heart Rate; Hypertension; Imidazoles; Infusions, Intravenous; Liver; Losartan; Male; Norepinephrine; Oleic Acid; Phenylephrine; Portal Vein; Prazosin; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Sodium Fluoride; Tetrazoles; Time Factors | 1997 |
Contribution of humoral systems to the recovery of blood pressure following severe haemorrhage.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Catecholamines; Diastole; Heart Rate; Hemodynamics; Hemorrhage; Hormone Antagonists; Losartan; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Systole | 1997 |
Brain ANG II and prostaglandins mediate the pressor response after central blockade of nitric oxide synthase.
Topics: Animals; Arginine; Blood Pressure; Cerebral Ventricles; Dose-Response Relationship, Drug; Heart Rate; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prazosin; Rats; Rats, Sprague-Dawley | 1998 |
Measurement of left ventricular maximal isovolumetric pressure in rats: effects of antihypertensive drugs and diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Catheterization; Diabetes Mellitus, Experimental; Female; Losartan; Metoprolol; Nifedipine; Prazosin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Ventricular Function, Left; Ventricular Pressure | 1998 |
Relationship between the increase in Ca2+ transient and contractile force induced by angiotensin II in aequorin-loaded rabbit ventricular myocardium.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aequorin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bupranolol; Calcium; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Microinjections; Myocardial Contraction; Myocardium; Prazosin; Pyridines; Rabbits; Stimulation, Chemical | 1998 |
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water | 1998 |
Alpha1-adrenergic plus angiotensin receptor blockade reduces atherosclerosis in apolipoprotein E-deficient mice.
Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Drug Therapy, Combination; Hypercholesterolemia; Losartan; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Prazosin; Propranolol; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors | 1998 |
Pressor and renal vasoconstrictor responses to acute systemic nitric oxide synthesis inhibition are independent of the sympathetic nervous system and angiotensin II.
Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prazosin; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Circulation; Sympathetic Nervous System; Vasoconstriction | 1999 |
Antihypertensive mechanisms underlying a novel salt-sensitive hypertensive model induced by sensory denervation.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Diuresis; Ganglia, Spinal; Hydralazine; Hypertension; Losartan; Male; Nerve Degeneration; Neurons, Afferent; Potassium; Prazosin; Rats; Rats, Wistar; Sodium; Sodium, Dietary | 1999 |
Blood pressure variability in established L-NAME hypertension in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Prazosin; Rats; Rats, Wistar; Time Factors | 1999 |
The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Alkaloids; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Aspartic Acid Endopeptidases; Benzophenanthridines; Bosentan; Captopril; Catalase; Coronary Vessels; Endothelin-Converting Enzymes; Endothelins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Free Radicals; Glycopeptides; Guinea Pigs; Heart; Losartan; Male; Metalloendopeptidases; Muscle Proteins; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitroprusside; Oxidative Stress; Phenanthridines; Prazosin; Protein Kinase C; Reactive Oxygen Species; Sulfonamides; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2000 |
Interaction between AT1 and alpha1-adrenergic receptors in cardiomyopathic hamsters.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Aorta; Cardiomyopathies; Cricetinae; Disease Models, Animal; Enalapril; Humans; Losartan; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; Receptors, Angiotensin; Vascular Resistance | 2000 |
Antihypertensive monotherapy and cardiovascular responses to an acoustic startle stimulus.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Analysis of Variance; Antihypertensive Agents; Atenolol; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Prazosin; Reflex, Startle; Stroke Volume; Vascular Resistance | 2001 |
Effects of losartan, prazosin and a vasopressin V1-receptor antagonist on renal and femoral blood flow in conscious sheep.
Topics: Angiotensin Receptor Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Cardiac Output; Consciousness; Female; Femoral Artery; Heart Rate; Losartan; Prazosin; Pulmonary Wedge Pressure; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Renal Circulation; Sheep | 2001 |
Neural and hormonal control of arterial pressure during cold exposure in unanesthetized week-old rats.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Body Temperature; Body Temperature Regulation; Cold Temperature; Female; Heart Rate; Hormone Antagonists; Losartan; Oxygen Consumption; Prazosin; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vocalization, Animal | 2001 |
Losartan increases renal blood flow during isoflurane anesthesia in sheep.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Antihypertensive Agents; Female; Hemodynamics; Hindlimb; Isoflurane; Losartan; Osmolar Concentration; Prazosin; Regional Blood Flow; Renal Circulation; Sheep; Vasopressins | 2001 |
Mechanisms involved in the water intake-related pressor response in the rat.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Brazil; Diazepam; Dose-Response Relationship, Drug; Drinking; Heart Rate; Idazoxan; Lidocaine; Losartan; Male; Mecamylamine; Models, Animal; Muscle Relaxants, Central; Prazosin; Quinine; Rats; Rats, Wistar; Sodium Chloride; Tropanes; Water | 2002 |
Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle.
Topics: Angiotensin II; Animals; Imidazoles; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2002 |
The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.
Topics: 4-Aminopyridine; Adrenalectomy; Adrenergic Antagonists; Amifampridine; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indomethacin; Losartan; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phentolamine; Potassium Channel Blockers; Prazosin; Protein Kinase C; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Staurosporine; Sulfonamides; Vascular Resistance; Vasoconstriction | 2003 |
"A la carte" treatment of portal hypertension or just "hors d'oeuvres".
Topics: Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Losartan; Prazosin; Propranolol | 2003 |
Interaction between paraventricular nucleus and medial septal area on the renal effects induced by adrenaline.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Epinephrine; Kidney; Losartan; Male; Neural Pathways; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Septal Nuclei; Urine | 2004 |
Neurohumoral mechanisms involved in the hypertensive response elicited by bilateral carotid occlusion in conscious intact or chronically sympathectomized rats.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Carotid Artery Diseases; Consciousness; Hypertension; Losartan; Male; Prazosin; Rats; Rats, Wistar; Renin-Angiotensin System; Sympathectomy, Chemical; Sympathetic Nervous System; Sympathomimetics; Tyramine | 2004 |
Adrenergic origin of very low-frequency blood pressure oscillations in the unanesthetized rat.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Arginine Vasopressin; Barium Sulfate; Blood Pressure; Calcium Channel Blockers; Consciousness; Epinephrine; Ganglionic Blockers; Hemodynamics; Hexamethonium; Losartan; Nifedipine; Norepinephrine; Potassium Channel Blockers; Prazosin; Propranolol; Rats; Rats, Inbred WKY; Receptors, Adrenergic; Vasoconstrictor Agents; Yohimbine | 2006 |
Angiotensin II is a critical mediator of prazosin-induced angiogenesis in skeletal muscle.
Topics: Angiotensin II; Animals; Losartan; Muscle, Skeletal; Neovascularization, Physiologic; Prazosin; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride; Vascular Endothelial Growth Factor A; Vasodilator Agents | 2007 |
Delayed effects of hypotensive drugs on structural characteristics of the renal glomerular system in hypertensive NISAG rats.
Topics: Animals; Antihypertensive Agents; Enalapril; Hypertension; Kidney Glomerulus; Losartan; Male; Nifedipine; Prazosin; Rats; Time Factors | 2007 |
Revelation on the potency of α(1) -blockers - parallel blockade of angiotensin II receptor: a new finding.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Doxazosin; Imidazoles; In Vitro Techniques; Losartan; Male; Molecular Structure; Prazosin; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents | 2012 |
Increased activity of the renin-angiotensin and sympathetic nervous systems is required for regulation of the blood pressure in rats fed a low-protein diet.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterial Pressure; Diet, Protein-Restricted; Enalapril; Heart Rate; Losartan; Male; Prazosin; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sympathetic Nervous System | 2013 |
Structural characteristics of renal glomerular system in ISIAH rats under conditions of chronic stress and preventive hypotensive drug therapy.
Topics: Animals; Antihypertensive Agents; Enalapril; Kidney Glomerulus; Losartan; Male; Prazosin; Rats; Stress, Physiological | 2011 |
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Heart; Hypertension; Longitudinal Studies; Losartan; Prazosin; Rats; Rats, Inbred SHR; Rats, Wistar; Treatment Outcome; Vasodilator Agents | 2013 |
Intravital Förster resonance energy transfer imaging reveals elevated [Ca2+]i and enhanced sympathetic tone in femoral arteries of angiotensin II-infused hypertensive biosensor mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biosensing Techniques; Calcium; Calcium Signaling; Calmodulin; Femoral Artery; Fluorescence Resonance Energy Transfer; Hexamethonium; Hypertension; Infusions, Intravenous; Losartan; Mice; Muscle, Smooth, Vascular; Prazosin; Sympathetic Nervous System; Vasoconstriction | 2013 |
Protective effects of MCR-1329, a dual α1 and angII receptor antagonist, in mineralocorticoid-induced hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Chromones; Desoxycorticosterone Acetate; Endothelium, Vascular; Hypertension; Losartan; Male; Mineralocorticoids; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Prazosin; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 2016 |
Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Glucose; Hemodynamics; Hypertension, Portal; Liver; Losartan; Male; Prazosin; Propranolol; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors | 2018 |
SERS determination of the antihypertensive drugs prazosin and losartan by using silver nanoparticles coated with β-cyclodextrin.
Topics: Antihypertensive Agents; beta-Cyclodextrins; Losartan; Metal Nanoparticles; Particle Size; Prazosin; Silver; Spectrum Analysis, Raman; Surface Properties | 2019 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |