losartan and piperidines

losartan has been researched along with piperidines in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, H; Kaida, T; Kozawa, O; Matsuno, H; Niwa, M; Uematsu, T1
Kasparov, S; Paton, JF1
Asico, LD; Bek, M; Eisner, GM; Goldstein, DS; Grandy, DK; Jose, PA; Li, XX; Rubinstein, M; Yang, Z1
Bkaily, G; Brochu, I; D'Orléans-Juste, P; Labonté, J1
Capuano, V; Coulombe, A; Deroubaix, E; Ferron, L; Renaud, JF; Ruchon, Y1
Abdel-Salam, OM; Arbid, MS; el-Batran, SA; el-Shenawy, SM; Nofal, SM1
Boemke, W; Francis, RC; Klein, A; Philippi-Höhne, C; Pickerodt, PA; Reyle-Hahn, MS1
Boyd, R; Ding, LL; Rätsep, MT; Wang, HD1
Inagaki, M; Kawada, T; Li, M; Sugimachi, M; Uemura, K; Zheng, C1
Chen, A; Chen, YM1
Akhtar, M; Hass, C; Khanam, R; Najmi, AK; Panda, BP1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R1
Carter, JJ; Fretwell, LV; Woolard, J1
Konczalla, J; Mrosek, J; Seifert, V; Vatter, H; Wanderer, S1
Guo, CX; Li, X; Liu, JY; Liu, SK; Liu, ZQ; Luo, M; Pei, Q; Xie, P; Yang, GP; Yin, JY; Zheng, Y; Zhou, HH1
Collins, C; Ernault, E; Fuhr, R; Gangaram-Panday, S; Passier, P; Treijtel, N; van Bruijnsvoort, M1

Trials

1 trial(s) available for losartan and piperidines

ArticleYear
A Cocktail Interaction Study Evaluating the Drug-Drug Interaction Potential of the Perpetrator Drug ASP8477 at Multiple Ascending Dose Levels.
    Clinical pharmacology in drug development, 2019, Volume: 8, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Losartan; Male; Midazolam; Middle Aged; Omeprazole; Piperidines; Pyridines; Young Adult

2019

Other Studies

15 other study(ies) available for losartan and piperidines

ArticleYear
GR144053, a fibrinogen receptor antagonist, enhances the suppression of neointima formation by losartan, an angiotensin II receptor antagonist, in the injured carotid artery of hamster.
    British journal of pharmacology, 1997, Volume: 122, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Carotid Arteries; Cell Division; Cricetinae; Drug Administration Schedule; Drug Synergism; Losartan; Male; Piperazines; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex

1997
Differential effects of angiotensin II on cardiorespiratory reflexes mediated by nucleus tractus solitarii - a microinjection study in the rat.
    The Journal of physiology, 1999, Nov-15, Volume: 521 Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradycardia; Chemoreceptor Cells; Heart Rate; Losartan; Microinjections; Neurokinin-1 Receptor Antagonists; Phrenic Nerve; Piperidines; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reflex; Respiration; Respiratory Physiological Phenomena; Solitary Nucleus; Substance P

1999
Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3

    Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Body Weight; Catechols; Endothelin Receptor Antagonists; Endothelin-1; Female; Genotype; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Oligopeptides; Phentolamine; Piperidines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic; Receptors, Dopamine D2; Receptors, Endothelin; Sodium; Sodium-Potassium-Exchanging ATPase; Urodynamics; Viper Venoms

2001
Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Myocardium; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Precursors; Receptor, Bradykinin B2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Endothelin; RNA, Messenger; Sodium Chloride, Dietary

2002
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
    Circulation research, 2003, Dec-12, Volume: 93, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; Calcium Channels, T-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Constriction, Pathologic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Gene Expression; Losartan; Male; Membrane Potentials; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nickel; Nitriles; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Sulfonamides

2003
Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.
    Pharmacological research, 2004, Volume: 50, Issue:2

    Topics: Alloxan; Animals; Blood Glucose; Blood Proteins; Carbamates; Cholesterol, LDL; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Therapy, Combination; Egypt; Fosinopril; Gliclazide; Hyperlipidemias; Hypolipidemic Agents; Lipids; Losartan; Male; Piperidines; Rats; Rats, Sprague-Dawley; Triglycerides

2004
Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:6

    Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dogs; Female; Hemodynamics; Hemorrhage; Hypotension; Losartan; Piperidines; Remifentanil; Xenon

2010
ETA and ETB receptors are expressed in vascular adventitial fibroblasts.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Collagen Type I; Connective Tissue; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Losartan; Mice; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Viper Venoms

2011
Adding the acetylcholinesterase inhibitor, donepezil, to losartan treatment markedly improves long-term survival in rats with chronic heart failure.
    European journal of heart failure, 2014, Volume: 16, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cholinesterase Inhibitors; Chronic Disease; Disease Models, Animal; Disease Progression; Donepezil; Drug Synergism; Drug Therapy, Combination; Heart Failure; Indans; Losartan; Myocardial Infarction; Piperidines; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vagus Nerve

2014
Donepezil, a potential therapeutic agent for heart failure.
    European journal of heart failure, 2015, Volume: 17, Issue:2

    Topics: Animals; Heart Failure; Indans; Losartan; Myocardial Infarction; Piperidines

2015
Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats.
    Drug research, 2016, Volume: 66, Issue:6

    Topics: Angiotensin II; Animals; Antioxidants; Cardiotonic Agents; Histamine Agonists; Histamine H3 Antagonists; Imidazoles; Isoproterenol; Losartan; Male; Myocardial Infarction; Myocardium; Norepinephrine; Piperidines; Rats; Renin-Angiotensin System; Sympathetic Nervous System; Thiourea

2016
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation

2016
Effects of 4 multitargeted receptor tyrosine kinase inhibitors on regional hemodynamics in conscious, freely moving rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Consciousness; Hemodynamics; Indazoles; Losartan; Male; Niacinamide; Phenylurea Compounds; Piperidines; Propranolol; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Regional Blood Flow; Sorafenib; Sulfonamides

2017
Crosstalk between the angiotensin and endothelin system in the cerebrovasculature after experimental induced subarachnoid hemorrhage.
    Neurosurgical review, 2018, Volume: 41, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Basilar Artery; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Losartan; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Subarachnoid Hemorrhage; Vasoconstriction; Vasodilation; Vasospasm, Intracranial

2018
Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:8

    Topics: Adult; Asian People; Biphenyl Compounds; Blood Glucose; Carbamates; Cells, Cultured; China; Dose-Response Relationship, Drug; Drug Interactions; Genotype; Healthy Volunteers; Humans; Imidazoles; Irbesartan; Liver-Specific Organic Anion Transporter 1; Losartan; Male; Piperidines; Polymorphism, Single Nucleotide; Tetrazoles; Valsartan; Young Adult

2018