losartan and phenylephrine

losartan has been researched along with phenylephrine in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	26 (44.07)	18.2507
2000's	15 (25.42)	29.6817
2010's	18 (30.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brecher, P; Chobanian, AV; Crawford, DC; Farivar, RS	1
Madwed, JB; Winquist, RJ	1
Henrion, D; Levy, BI; Qiu, HY	1
Kumagai, K; Reid, IA	2
Clark, KL; Robertson, MJ; Wragg, A	1
Dick, LB; Guan, H; Lin, L; Miller, KB; Nasjletti, A; Pucci, ML	1
Barrett, RJ; Droppleman, DA	1
Näveri, L; Saavedra, JM; Strömberg, C	1
Ida, F; Krieger, EM; Moreira, ED; Pires, MD	1
Benessiano, J; Caputo, L; Duriez, M; Henrion, D; Heymes, C; Levy, BI; Poitevin, P; Samuel, JL	1
Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM	2
Brooks, VL; Xu, L	1
Benessiano, J; Dowell, FJ; Henrion, D; Levy, BI; Poitevin, P	1
Minnick, A; Nuyt, AM; Robillard, JE; Segar, JL	1
Borthayre, A; Giaid, A; Haleen, S; Harrison, DG; Keiser, J; Kurz, S; Laursen, JB; Rajagopalan, S	1
Dumont, CJ; Grekin, RJ; Vollmer, AP; Watts, SW; Webb, RC	1
May, CN; McAllen, RM	1
Comiter, CV; Kifor, I; Sullivan, MP; Yalla, SV	1
Liu, JL; Murakami, H; Zucker, IH	1
Davis, EA; Widdop, RE; Zwart, AS	1
Butcher, JW; Kasparov, S; Paton, JF	1
Baan, J; Chang, PC; Pfaffendorf, M; van der Wal, AC; van Zwieten, PA	1
Huang, BS; Leenen, FH; Zhang, W	1
Ardaillou, R; Chansel, D; Henrion, D; Levy, BI; Loufrani, L	1
Fujimura, A; Harada, K; Kawaguchi, A; Ohmori, M	1
Porter, JP	1
Brooks, VL; Kane, CM; Welch, LS	1
Bezerra, SM; dos Santos, CM; Krieger, EM; Michelini, LC; Moreira, ED	1
Crozier, S; Endre, ZH; Gobe, G; Guan, Z; Manley, SW; Matthias, A; Willgoss, DA	1
Ayajiki, K; Kashiwagi, A; Nishio, Y; Okamura, T; Shinozaki, K; Sugaya, T	1
May, CN; McAllen, RM; Mogulkoc, R; Watson, AM	1
Hagiwara, Y; Kubo, T	1
Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P	1
Alonso, MJ; Balfagón, G; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE	1
Padilha, AS; Rossoni, LV; Vassallo, DV; Xavier, FE	1
Gao, XY; Guo, R; Han, Y; Wang, HJ; Zhang, F; Zhang, Y; Zhu, GQ	1
Cheng, L; Jiang, LQ; Krawczyk, M; Lakatta, EG; Monticone, R; Pintus, G; Spinetti, G; Talan, M; Wang, M; Zhang, J; Zhao, D	1
De Angelis, K; Irigoyen, M; Maeda, C; Oliveira, E; Oliveira, V; Schaan, B	1
Falone, AE; Khalil, RA; Koledova, VV; Qiao, X; Stennett, AK	1
Angeli, JK; Casali, EA; Fürstenau, CR; Ramos, DB; Sarkis, JJ; Souza, DO; Stefanon, I; Vassallo, DV	1
Bouhuizen, AM; Danser, AH; de Waard, MC; Duncker, DJ; Essers, J; Lankhorst, S; Moltzer, E; Ramnath, NW; Rouwet, EV; Swagemakers, SM; te Riet, L; van der Spek, PJ; van Esch, JH; van Heijningen, PM; van Veghel, R; Vermeij, M	1
Abdulla, MH; Abdullah, NA; Johns, EJ; Sattar, MA	2
Hanson, MA; Itoh, S; Miyakawa, M; Musha, Y; Ohtsuji, M; Saito, T; Takeda, S	1
Kong, X; Li, XY; Ma, MZ; Qin, L; Su, Q; Wang, GD; Zhang, DY; Zhang, Y	1
Almenara, CC; Angeli, JK; Broseghini-Filho, GB; Faria, Tde O; Padilha, AS; Stefanon, I; Vassallo, DV; Vescovi, MV	1
A Faria, J; Anhê, GF; Antunes, E; Calmasini, FB; Gontijo, JA; Mónica, FZ; Muscará, MN; Ramos-Filho, AC; Teixeira, SA; Zanesco, A	1
Kawabe, K; Kawabe, T; Sapru, HN	1
de Oliveira Faria, T; Furieri, LB; Lizardo, JH; Padilha, AS; Silveira, EA; Siman, FD; Stefanon, I; Vassallo, DV; Vescovi, MV	1
Bobadilla-Lugo, RA; Bracho-Valdés, I; Ibarra-Barajas, M; Tufiño, C; Villanueva-López, C	1
Farnham, MM; Hildreth, CM; Phillips, JK; Pilowsky, PM; Saha, M; Sun, QJ; Yao, Y	1
Bouwer, GT; Brown, CH; Han, SY; Korpal, AK; Schwenke, DO; Seymour, AJ	1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R	1
Arain, SR; Ebert, TJ; Freed, JK; Novalija, J; Pagel, PS	1
Alonso, MJ; Fioresi, M; Salaices, M; Simões, MR; Toscano, CM; Vassallo, DV	1
Chianca, D; de Abreu, ARR; de Menezes, RCA; de Souza, AMA; Ji, H; Mesquita, LBT; Pai, AV; Sandberg, K; West, CA	1

Trials

2 trial(s) available for losartan and phenylephrine

Article	Year
Influence of losartan on alpha-adrenoceptor-mediated vasoconstrictor response in humans. Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:1 Topics: Adult; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Fingers; Heart Rate; Humans; Losartan; Male; Phenylephrine; Receptors, Adrenergic, alpha; Vasoconstriction; Vasoconstrictor Agents	2000
Short-Term Angiotensin Subtype 1 Receptor Blockade Does Not Alter the Circulatory Responses to Sympathetic Nervous System Modulation in Healthy Volunteers Before and During Sevoflurane Anesthesia: Results of a Pilot Study. Journal of cardiothoracic and vascular anesthesia, 2016, Volume: 30, Issue:6 Topics: Adult; Anesthetics, Inhalation; Angiotensin II Type 1 Receptor Blockers; Arterial Pressure; Cross-Over Studies; Double-Blind Method; Female; Forearm; Healthy Volunteers; Humans; Losartan; Male; Methyl Ethers; Phenylephrine; Pilot Projects; Sevoflurane; Sympathetic Nervous System; Vascular Resistance; Vasoconstrictor Agents; Young Adult	2016

Article

Year

Influence of losartan on alpha-adrenoceptor-mediated vasoconstrictor response in humans.

Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:1

Topics: Adult; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Fingers; Heart Rate; Humans; Losartan; Male; Phenylephrine; Receptors, Adrenergic, alpha; Vasoconstriction; Vasoconstrictor Agents

2000

Short-Term Angiotensin Subtype 1 Receptor Blockade Does Not Alter the Circulatory Responses to Sympathetic Nervous System Modulation in Healthy Volunteers Before and During Sevoflurane Anesthesia: Results of a Pilot Study.

Journal of cardiothoracic and vascular anesthesia, 2016, Volume: 30, Issue:6

Topics: Adult; Anesthetics, Inhalation; Angiotensin II Type 1 Receptor Blockers; Arterial Pressure; Cross-Over Studies; Double-Blind Method; Female; Forearm; Healthy Volunteers; Humans; Losartan; Male; Methyl Ethers; Phenylephrine; Pilot Projects; Sevoflurane; Sympathetic Nervous System; Vascular Resistance; Vasoconstrictor Agents; Young Adult

2016

Other Studies

57 other study(ies) available for losartan and phenylephrine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effect of angiotensin II blockade on the fibroproliferative response to phenylephrine in the rat heart. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:4 Pt 2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blotting, Northern; Fibrosis; Glyceraldehyde-3-Phosphate Dehydrogenases; Heart; Imidazoles; Indoles; Losartan; Male; Myocardium; Phenylephrine; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Renin-Angiotensin System; RNA; Tetrazoles	1995
Effects of losartan (DuP753) and enalaprilat on the mean arterial pressure response to phenylephrine. Journal of hypertension, 1994, Volume: 12, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Heart Rate; Imidazoles; Infusions, Intravenous; Losartan; Phenylephrine; Rabbits; Renin-Angiotensin System; Tetrazoles	1994
Endogenous angiotensin II enhances phenylephrine-induced tone in hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:3 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; Indoles; Losartan; Mesenteric Arteries; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Tetrazoles; Vasomotor System	1994
Angiotensin II exerts differential actions on renal nerve activity and heart rate. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Male; Phenylephrine; Pressoreceptors; Rabbits; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles	1994
Modulation of tachyphylaxis to angiotensin II in rabbit isolated aorta by the angiotensin AT1 receptor antagonist, losartan. Regulatory peptides, 1994, Feb-24, Volume: 50, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Reproducibility of Results; Tachyphylaxis; Tetrazoles	1994
Vascular responsiveness to nitric oxide synthesis inhibition in hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 1 Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Aortic Coarctation; Arginine; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction	1994
Losartan inhibits sympathetic and cardiovascular responses to carotid occlusion. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Carotid Arteries; Constriction; Heart Rate; Imidazoles; Kidney; Losartan; Nitroprusside; Phenylephrine; Rabbits; Sympathetic Nervous System; Tetrazoles	1994
Interactions of adenosine A1 receptor-mediated renal vasoconstriction with endogenous nitric oxide and ANG II. The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2 Topics: Adenine; Adenosine; Angiotensin II; Animals; Arginine; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regional Blood Flow; Renal Circulation; Serotonin; Tetrazoles; Thromboxane A2; Vascular Resistance; Vasoconstriction	1993
Angiotensin II AT2 receptor stimulation extends the upper limit of cerebral blood flow autoregulation: agonist effects of CGP 42112 and PD 123319. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:1 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Imidazoles; Injections, Intravenous; Losartan; Male; Oligopeptides; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles	1994
DuP 753 is more effective than captopril on baroreceptor function in high-renin hypertension. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Hypertension; Imidazoles; Losartan; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Reflex; Renin; Tetrazoles; Time Factors	1994
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure. The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles	1996
Losartan reduces phenylephrine constrictor response in aortic rings from spontaneously hypertensive rats. Role of nitric oxide and angiotensin II type 2 receptors. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:6 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Vasoconstriction	1996
ANG II chronically supports renal and lumbar sympathetic activity in sodium-deprived, conscious rats. The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 2 Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Anti-Arrhythmia Agents; Biphenyl Compounds; Blood Pressure; Central Venous Pressure; Heart Rate; Imidazoles; Kidney; Losartan; Lumbosacral Region; Male; Methoxamine; Phenylephrine; Rats; Rats, Sprague-Dawley; Sodium; Sympathetic Nervous System; Tetrazoles; Time Factors	1996
Effects of chronic losartan treatment on vascular reactivity in normotensive rats. Journal of hypertension, 1997, Volume: 15, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Phenylephrine; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles; Vasoconstriction	1997
Role of endogenous ANG II and AT1 receptors in regulating arterial baroreflex responses in newborn lambs. The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Animals, Newborn; Antihypertensive Agents; Arteries; Baroreflex; Biphenyl Compounds; Cardiovascular Physiological Phenomena; Imidazoles; Losartan; Phenylephrine; Receptors, Angiotensin; Sheep; Tetrazoles	1997
Role for endothelin-1 in angiotensin II-mediated hypertension. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:1 Pt 1 Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Serotonin; Staining and Labeling; Tetrazoles; Time Factors; Vasoconstrictor Agents	1997
Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: Acetylcholine; Aldosterone; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Corticosterone; Epinephrine; Fatty Acids, Nonesterified; Heart Rate; Hypertension; Imidazoles; Infusions, Intravenous; Liver; Losartan; Male; Norepinephrine; Oleic Acid; Phenylephrine; Portal Vein; Prazosin; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Sodium Fluoride; Tetrazoles; Time Factors	1997
Baroreceptor-independent renal nerve inhibition by intracerebroventricular angiotensin II in conscious sheep. The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 2 Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Central Venous Pressure; Female; Imidazoles; Injections, Intraventricular; Kidney; Losartan; Neural Inhibition; Phenylephrine; Pressoreceptors; Sheep; Sympathetic Nervous System; Tetrazoles	1997
Effect of angiotensin II on corpus cavernosum smooth muscle in relation to nitric oxide environment: in vitro studies in canines. International journal of impotence research, 1997, Volume: 9, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dogs; Electric Stimulation; Enzyme Inhibitors; Losartan; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penis; Phenylephrine	1997
Angiotensin II-nitric oxide interaction on sympathetic outflow in conscious rabbits. Circulation research, 1998, Mar-09, Volume: 82, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Consciousness; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System	1998
Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR. Kidney international. Supplement, 1998, Volume: 68 Topics: Acetylcholine; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Kidney; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitrites; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation	1998
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors. British journal of pharmacology, 1998, Volume: 125, Issue:7 Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction	1998
Angiotensin II receptors within the nucleus of the solitary tract mediate the developmental attenuation of the baroreceptor vagal reflex in pre-weaned rats. Journal of the autonomic nervous system, 1998, Dec-11, Volume: 74, Issue:2-3 Topics: Age Factors; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Antihypertensive Agents; Blood Pressure; Halothane; Heart Rate; Hydralazine; Losartan; Male; Microinjections; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reflex; Solitary Nucleus; Sympathomimetics; Urethane; Vagus Nerve; Weaning	1998
Influence of losartan and nicardipine on the contractile responses of human subcutaneous arteries and veins to angiotensin II. Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1 Topics: Acetylcholine; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arteries; Blood Vessels; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Losartan; Nicardipine; Phenylephrine; Potassium; Skin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Veins	1999
Brain renin-angiotensin system and sympathetic hyperactivity in rats after myocardial infarction. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Cardiotonic Agents; Enzyme Inhibitors; Guanabenz; Heart Failure; Heart Rate; Injections, Intraventricular; Losartan; Male; Myocardial Infarction; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System	1999
Functional evidence for an angiotensin IV receptor in rat resistance arteries. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Animals; Benzimidazoles; Biphenyl Compounds; Drug Interactions; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Serotonin; Tachyphylaxis; Tetrazoles; Vascular Resistance	1999
Contribution of central ANG II to acute stress-induced changes in baroreflex function in young rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cerebral Ventricles; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Losartan; Male; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Restraint, Physical; Stress, Psychological; Sympathetic Nervous System	2000
Role of angiotensin II in altered baroreflex function of conscious rabbits during late pregnancy. American journal of obstetrics and gynecology, 2001, Volume: 184, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Female; Fetal Viability; Heart Rate; Litter Size; Logistic Models; Losartan; Nitroprusside; Phenylephrine; Pregnancy; Pregnancy, Animal; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstrictor Agents	2001
Chronic AT(1) receptor blockade alters autonomic balance and sympathetic responses in hypertension. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Heart Rate; Hypertension; Losartan; Male; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents	2001
Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxide. Acta physiologica Scandinavica, 2003, Volume: 179, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic N-Oxides; Endothelium-Dependent Relaxing Factors; Erythrocytes; Glomerular Filtration Rate; Homeostasis; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Spin Labels; Vasoconstriction	2003
Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Calcimycin; Culture Techniques; Endothelium, Vascular; Insulin Resistance; Losartan; Male; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Superoxides; Vasoconstriction; Vasoconstrictor Agents	2004
Stimulation of cardiac sympathetic nerve activity by central angiotensinergic mechanisms in conscious sheep. American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:6 Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Baroreflex; Blood Pressure; Female; Ganglionic Blockers; Heart; Heart Rate; Injections, Intraventricular; Kidney; Losartan; Ovariectomy; Phenylephrine; Sheep; Sympathetic Nervous System; Sympathomimetics	2004
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats. Brain research, 2004, May-01, Volume: 1006, Issue:2 Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine	2004
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. Circulation research, 2004, Jun-25, Volume: 94, Issue:12 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents	2004
Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries. British journal of pharmacology, 2004, Volume: 143, Issue:1 Topics: Animals; Antihypertensive Agents; Blotting, Western; Cardiotonic Agents; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Ouabain; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstrictor Agents	2004
Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:3 Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Enalaprilat; Endothelium, Vascular; Glucose; Hexamethonium; Injections, Intravenous; Losartan; Male; Muscle, Smooth, Vascular; Ouabain; Perfusion; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Tail; Time Factors; Tromethamine; Vasodilation	2004
AT1 receptor in rostral ventrolateral medulla mediating blunted baroreceptor reflex in spontaneously hypertensive rats. Acta pharmacologica Sinica, 2004, Volume: 25, Issue:11 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Losartan; Male; Medulla Oblongata; Oligodeoxyribonucleotides, Antisense; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1	2004
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats. The American journal of pathology, 2005, Volume: 167, Issue:5 Topics: Adrenergic alpha-Agonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Carotid Arteries; Collagen; Dipeptides; Immunohistochemistry; Losartan; Male; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Culture Techniques; Phenylephrine; Protease Inhibitors; Rats; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tunica Intima; Vasoconstrictor Agents	2005
Chronic salt loading and cardiovascular-associated changes in experimental diabetes in rats. Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:7 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arginine Vasopressin; Baroreflex; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Ganglionic Blockers; Heart Rate; Hematocrit; Hexamethonium; Hormone Antagonists; Hypertension; Kidney; Losartan; Male; Nitroprusside; Organ Size; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins	2007
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phenylephrine; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2009
Gadolinium increases the vascular reactivity of rat aortic rings. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:5 Topics: Animals; Antihypertensive Agents; Aorta; Dose-Response Relationship, Drug; Enalaprilat; Endothelium, Vascular; Female; Gadolinium; Losartan; Male; NG-Nitroarginine Methyl Ester; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilation	2011
Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade. PloS one, 2011, Volume: 6, Issue:8 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Aorta, Thoracic; Aortic Aneurysm; Extracellular Matrix Proteins; Female; Humans; Immunohistochemistry; In Vitro Techniques; Losartan; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phenylephrine; Pregnancy; Receptor, Angiotensin, Type 1; Smad2 Protein; Transcriptome; Transforming Growth Factor beta; Vasoconstriction; Vasoconstrictor Agents	2011
The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats. Journal of physiology and biochemistry, 2012, Volume: 68, Issue:3 Topics: Angiotensin II; Animals; Body Weight; Carbazoles; Carvedilol; Fructose; Glucose Tolerance Test; Hemodynamics; Insulin Resistance; Kidney; Losartan; Male; Norepinephrine; Phenylephrine; Propanolamines; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents	2012
Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams. The journal of obstetrics and gynaecology research, 2012, Volume: 38, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II Type 1 Receptor Blockers; Animals; Diet, Protein-Restricted; Female; Hypertension; Losartan; Nitroprusside; Peripheral Vascular Diseases; Phenylephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Random Allocation; Rats; Rats, Wistar; Uterine Artery; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2012
Pioglitazone enhances the blood pressure-lowering effect of losartan via synergistic attenuation of angiotensin II-induced vasoconstriction. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:3 Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Drug Synergism; Endothelium, Vascular; Losartan; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Pioglitazone; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Systole; Thiazolidinediones; Tyrosine; Vasoconstriction; Vasodilation	2014
The effect of high-fructose intake on the vasopressor response to angiotensin II and adrenergic agonists in Sprague-Dawley rats. Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:4 Topics: Angiotensin II; Animals; Fructose; Hemodynamics; Losartan; Male; Methoxamine; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2	2013
Chronic cadmium treatment promotes oxidative stress and endothelial damage in isolated rat aorta. PloS one, 2013, Volume: 8, Issue:7 Topics: Acetophenones; Acetylcholine; Animals; Aorta; Blood Pressure; Body Weight; Cadmium; Catalase; Densitometry; Enalapril; Endothelium, Vascular; In Vitro Techniques; Losartan; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Phenylephrine; Rats; Superoxide Dismutase; Systole	2013
The renin-angiotensin system plays a major role in voiding dysfunction of ovariectomized rats. Life sciences, 2013, Nov-19, Volume: 93, Issue:22 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carbachol; Dose-Response Relationship, Drug; Estradiol; Female; In Vitro Techniques; Losartan; Lower Urinary Tract Symptoms; Ovariectomy; Peptidyl-Dipeptidase A; Phenylephrine; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Urethra; Urinary Bladder; Urination; Vasoconstrictor Agents	2013
Cardiovascular effect of angiotensin-(1-12) in the caudal ventrolateral medullary depressor area of the rat. American journal of physiology. Heart and circulatory physiology, 2014, Volume: 306, Issue:3 Topics: Adrenergic alpha-1 Receptor Agonists; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Captopril; Heart Rate; Losartan; Male; Medulla Oblongata; Nitroprusside; Peptide Fragments; Phenylephrine; Rats; Rats, Wistar; Vasomotor System	2014
Low-dose chronic lead exposure increases systolic arterial pressure and vascular reactivity of rat aortas. Free radical biology & medicine, 2014, Volume: 67 Topics: Acetophenones; Animals; Antioxidants; Aorta; Blood Pressure; Chronic Disease; Cyclooxygenase 2 Inhibitors; Indomethacin; Lead Poisoning; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Renin-Angiotensin System; Superoxide Dismutase; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2014
Experimental gestational diabetes mellitus induces blunted vasoconstriction and functional changes in the rat aorta. BioMed research international, 2014, Volume: 2014 Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Humans; Losartan; Phenylephrine; Pregnancy; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation	2014
The effect of losartan on differential reflex control of sympathetic nerve activity in chronic kidney disease. Journal of hypertension, 2015, Volume: 33, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Pathways; Baroreflex; Kidney; Losartan; Lumbosacral Region; Male; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Sympathetic Nervous System	2015
Induction of hypertension blunts baroreflex inhibition of vasopressin neurons in the rat. The European journal of neuroscience, 2015, Volume: 42, Issue:9 Topics: Adrenergic alpha-1 Receptor Agonists; Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Hypertension; Losartan; Male; Neurons; Phenylephrine; Pituitary Gland; Rats; Rats, Inbred F344; Rats, Transgenic; Subfornical Organ; Vasopressins	2015
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity. Life sciences, 2016, Oct-15, Volume: 163 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation	2016
Sub-chronic lead exposure produces β Life sciences, 2017, Jul-01, Volume: 180 Topics: Animals; Arterial Pressure; Cardiovascular Diseases; Down-Regulation; Heart Rate; Hexamethonium; Hypertension; Indomethacin; Isoproterenol; Lead; Losartan; Male; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Risk Factors	2017
Role of the Renin Angiotensin System in Blood Pressure Allostasis-induced by Severe Food Restriction in Female Fischer rats. Scientific reports, 2018, 07-09, Volume: 8, Issue:1 Topics: Aldosterone; Allostasis; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Diet; Female; Losartan; Mesenteric Veins; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System	2018