Compounds > losartan

losartan and pd 123319

losartan has been researched along with pd 123319 in 473 studies

Research

Studies (473)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's217 (45.88)18.2507
2000's173 (36.58)29.6817
2010's79 (16.70)24.3611
2020's4 (0.85)2.80

Authors

AuthorsStudies
De León, H; Garcia, R1
Bird, IM; Magness, RR; Mason, JI; Rainey, WE1
Chaki, S; Inagami, T1
Achard, JM; Gardin, JP; Houillier, P; Lazar, G; Paillard, M; Poggioli, J1
Boswell, F; Dornan, ES; Kelly, M; Lyall, F; McQueen, J1
Damon, TH; Douglas, JG; Ernsberger, P; Zhou, J1
Garcia, R; Gauquelin, G1
Bennett, T; Gardiner, SM; Kemp, PA; Widdop, RE2
Kang, J; Posner, P; Sumners, C1
Bjork, FA; Hodges, JC; Keiser, JA; Taylor, DG1
Boulay, G; Escher, E; Guillemette, G; Luong, TT; Servant, G1
Crews, FT; Gyurko, R; Kimura, B; Kurian, P; Phillips, MI1
Byrd, EW; Carr, BR; Rainey, WE; Sinnokrot, RA1
Bardhan, S; Inagami, T; Kambayashi, Y; Shirai, H; Takahasi, K1
Giasson, E; Meloche, S1
Auch-Schwelk, W; Duske, E; Fleck, E; Hess, B; Hildebrandt, AG; Klein, U; Regitz-Zagrosek, V; Steffen, C1
Smith, RD1
de Gasparo, M; Levens, NR1
Chan, JY; Chan, SH; Yang, CC1
Ben, A; Cox, SL; Story, DF; Ziogas, J1
Madsen, KM; Tisher, CC; Tojo, A1
Agnati, LF; Fior, DR; Fuxe, K; Hedlund, PB; Narváez, JA; Yang, SN1
Garcia, NH; Garvin, JL1
Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD1
Miyazaki, H; Murakami, K; Naruse, M; Ohnishi, J; Ozawa, Y; Sugimoto, M; Tanaka, M; Usuki, S1
Näveri, L; Saavedra, JM; Strömberg, C4
Lantelme, P; Liu, KL; Lo, M; Sassard, J1
Cai, G; Gurdal, H; Johnson, MD; Seasholtz, TM1
Caride, VJ; Fernandez, LA; Näveri, L; Strömberg, C; Wicke, JD1
Burns, KD; Harris, RC; Inagami, T1
Bennett, T; Gardiner, SM; Widdop, RE1
Brown, KD; Corps, AN; Hadfield, KM; Smith, RD; Vaughan, TJ1
Cumin, F; De Gasparo, M; Levens, N; Macari, D; Whitebread, S1
Douglas, JG; Dulin, NO; Ernsberger, P; Suciu, DJ1
Chiu, AT; Keiser, J; Madison, AB; Nishimura, H; Patton, CM; Walker, OE1
Fleck, E; Hildebrandt, A; Neuss, M; Regitz-Zagrosek, V1
Imanaka, T; Mineo, C; Shimizu, H; Takada, K; Takano, T1
Armellino, DC; Crandall, DL; Herzlinger, HE; Kral, JG; Saunders, BD1
Haberl, RL1
Catalioto, RM; Criscuoli, M; Mizrahi, J; Renzetti, AR; Subissi, A1
Diamant, D; Ingelfinger, JR; Lopez, JJ; Lorell, BH; Schunkert, H; Tang, SS; Weinberg, EO1
Blake, DR; Knock, GA; Polak, JM; Suzuki, T; Walsh, DA; Wharton, J1
Adler-Graschinsky, E; Enero, MA; Gironacci, MM; Peña, C1
Li, BH; Rowland, NE; Rozelle, AK; Smith, GC1
Komorowski, J; Kunert-Radek, J; Pawlikowski, M; Stepień, H1
Cierco, M; Israel, A1
Becú-Villalobos, D; Díaz-Torga, GS; Lacau-Mengido, IM; Libertun, C; Thyssen, SM1
Becú-Villalobos, D; Díaz-Torga, GS; Libertun, C1
Hogarty, DC; Phillips, MI; Tran, DN1
Maita, ME; Mento, PF; Vernace, MA; Wilkes, BM1
Grupp, LA; Harding, S1
Fregly, MJ; Rowland, NE2
Honda, K; Iida-Kubota, E; Yazawa, H1
Bottari, S; De Gasparo, M; Levens, N; Macari, D; Whitebread, S1
Arendshorst, WJ; Chatziantoniou, C1
Hayashi, K; Saruta, T; Suzuki, H1
Feolde, E; Frelin, C; Vigne, P2
Cooney, AS; Fitzsimons, JT1
Tanabe, N; Tsujimoto, G; Ueno, A1
Bottari, SP; Brechler, V; de Gasparo, M; Jones, PW; Levens, NR1
Endoh, M; Ishihata, A1
Ferguson, AV; Li, Z1
Cook, MD; Cook, VI; Kimura, B; Phillips, MI; Wilcox, CS1
Naftolin, F; Nemeth, G; Pepperell, JR; Yamada, Y1
Hollenberg, MD; Laniyonu, A; Saifeddine, M; Yang, SG1
Porter, JP; Toney, GM2
Douglas, JG; Ernsberger, P; Hopfer, U; Ke, FC; Madhun, ZT; Zhou, J1
Dudley, DT; Summerfelt, RM1
Chou, L; Reid, IA; Wong, J1
Perrone, MH; Scheuer, DA1
Sim, MK; Soh, KS1
Carey, RM; Siragy, HM3
Gorczynska, E; Handelsman, DJ; Spaliviero, J1
Chua, BH; Chua, CC; Hamdy, RC3
Daemen, MJ; Fingerle, J; van Kleef, EM1
Brochu, M; Forcier, I; St-Louis, J1
Aldred, GP; Chai, SY; MacGregor, DP; Mendelsohn, FA; Moeller, I1
Rabkin, SW1
Chai, SK; Sim, MK1
Gelband, CH; Martens, JR; Posner, P; Sumners, C; Wang, D2
Benessiano, J; Caputo, L; Duriez, M; Henrion, D; Heymes, C; Levy, BI; Poitevin, P; Samuel, JL1
Barsuk, JH; Johnson, RF; Seidman, KJ; Weyhenmeyer, JA1
Kageyama, Y; Matsumoto, A; Murakami, M; Naitoh, M; Saruta, T; Suzuki, H; Tsujimoto, G1
Barbosa, SP; De Luca, LA; Menani, JV; Sugawara, AM1
Kim, HJ; Kim, KS; Lee, EJ; Lee, JH; Lee, WJ; Park, JS; Yang, EK1
Chow, SY; Fluharty, SJ; Galaverna, O; Liénard, F; Polidori, C; Sakai, RR1
Galaverna, O; Liénard, F; Martial, FP; Meile, MJ; Mousseau, MC; Nicolaïdis, S; Thornton, SN1
Findlay, AL1
Cachofeiro, V; Casal, MC; Lahera, V; Maeso, R; Munoz-Garcia, R; Navarro, J; Rodrigo, E; Ruilope, LM1
Harris, PJ; Hiranyachattada, S1
Benhaïm, A; Féral, C; Leymarie, P1
Cox, SL; Story, DF; Ziogas, J2
Georgiev, VP; Kambourova, TS; Lazarova, MB1
Breault, L; Gallo-Payet, N; Lehoux, JG2
Grochal, M; Kulig, A; Kunert-Radek, J; Mucha, S; Pawllkowski, M; Stepień, H; Zieliński, K1
Berrino, L; D'Amico, M; di Filippo, C; Rossi, F1
Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM1
Cervenka, L; Heller, J; Jelínek, F1
Clanachan, AS; Ford, WR; Jugdutt, BI1
Alcorn, D; Dean, R; MacGregor, D; Mendelsohn, FA; Zhuo, J1
Maita, ME; Mento, PF; Wilkes, BM1
Arendshorst, WJ; Zhu, Z1
Saward, L; Zahradka, P1
Hagiwara, H; Hirose, S; Hiruma, Y; Inoue, A1
Forster, C; le Tran, Y1
Arendshorst, WJ; Chatziantoniou, C; Kurtz, A; Ruan, X; Wagner, C1
Armour, JA; Horackova, M1
Higson, JT; Tallant, EA1
Fluharty, SJ; He, P; Hines, J; Reagan, LP; Siemens, IR; Yang, XD; Yee, DK1
Kunert-Radek, J; Pawlikowski, M1
Anversa, P; Cheng, W; Cigola, E; Kajstura, J; Li, P; Malhotra, A; Meggs, LG1
Ball, DL; Elliott, ME; Goodfriend, TL; Jefcoate, CR1
Henry, JL; Park, PD1
Camargo, GM; Camargo, LA; do-Prado, MH; Luiz, AC; Queiróz, RC; Renzi, A; Saad, WA1
Bendle, RD; Head, GA; Malpas, SC1
Blair-West, JR; Denton, DA; McKinley, MJ; Weisinger, RS1
Blair-West, JR; Denton, DA; Tarjan, E; Weisinger, RS1
Espinosa, E; Liu, G; Lüscher, TF; Oemar, BS1
Danser, AH; Lamers, JM; Saxena, PR; Schalekamp, MA; van Heugten, HA; van Kesteren, CA1
Chatterjee, PK; Hawksworth, GM; McLay, JS; Mistry, SK; Weerackody, RP1
Choy, PC; Hatch, GM; Kroeger, EA; Lee, D; Man, RY1
De Paolis, P; Enea, I; Gigante, B; Natale, A; Piras, O; Porcellini, A; Rubattu, S; Russo, R; Savoia, C; Volpe, M1
Hata, T; Makino, N; Otsuka, S; Sugano, M1
Albrecht, D; Ganten, D; Henklein, P1
Bankir, L; Bouby, N; Corvol, P; Hus-Citharel, A; Llorens-Cortes, C; Marchetti, J1
Mehta, JL; Phillips, MI; Yang, BC1
Blair-West, JR; Burns, P; Denton, DA; Tarjan, E; Weisinger, RS1
Baum, M; Quan, A; Quigley, R1
Fujimori, A; Inagaki, O; Kusayama, T; Okazaki, T; Satoh, Y; Shibasaki, M; Takanashi, M; Tokioka, T; Uchida, W; Yanagisawa, I1
Bird, IM; Briere, N; Ducharme, L; Lehoux, JG; Martel, D1
Dampney, RA; Hirooka, Y; Potts, PD1
Heller, J; Horácek, V1
Borg, TK; Carver, W; Fu, L; Price, RL; Simpson, DG; Terracio, L; Zhao, J1
Gohlke, P; Pees, C; Unger, T2
Frandsen, E; Ibsen, H; Petersen, JS; Worck, RH1
Li, JS; Schiffrin, EL; Touyz, RM1
Champion, HC; Czapla, MA; Kadowitz, PJ1
Averill, DB; Chappell, MC; Diz, DI; Ferrario, CM; Iyer, SN1
Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H1
Freel, RW; Hatch, M; Vaziri, ND2
Kling, L; Lamparter, S; Pfeilschifter, J; Schrader, M; Ziegler, R1
Goutsouliak, V; Rabkin, SW1
Brosnihan, KB; Chappell, MC; Ferrario, CM; Iyer, SN1
Galaverna, O; Liénard, F; Meile, MJ; Nicolaïdis, S; Thornton, SN1
D'Amico, M; Di Filippo, C; Rossi, F; Warner, TD1
Greene, AS; McCarthy, ET; Savin, VJ; Sharma, M; Sharma, R1
Andreis, PG; Belloni, AS; Gottardo, G; Macchi, V; Malendowicz, LK; Nussdorfer, GG1
Gottardo, G; Macchi, V; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG1
Endoh, M; Watanabe, A1
Alvarez Arroyo, MV; Caramelo, C; Casado, S; Castilla, MA; González-Pacheco, FR; López Farré, A; Montón, M; Tan, D1
Johns, EJ; Wong, PS1
Allen, SP; Chester, AH; Hafizi, S; Morgan, K; Yacoub, MH1
Häuser, W; Jöhren, O; Saavedra, JM1
Allen, AM1
Han, NL; Sim, MK1
Jiménez, E; Montiel, M1
Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ1
Breitbart, H; Gur, Y; Lax, Y; Rubinstein, S; Zamir, N1
Borland, JA; Catravas, JD; Chester, AH; Crabbe, S; Parkerson, JB; Yacoub, MH1
Fang, TC; Huang, WC1
Levy, BI; Marotte, F; Poitevin, P; Rappaport, L; Sabri, A; Samuel, JL1
Guimarães, S; Moura, D; Paiva, MQ1
Hata, T; Makino, N; Niho, Y; Otsuka, S; Sawada, S; Sugano, M1
Byron, KL; Govindarajan, G; Griffin, TM; Lucchesi, PA; Sabri, A; Samarel, AM1
Fukuda, K; Izumo, S1
Buchko, J; Lalonde, C; Nguyen, M; Saward, L; Thomas, S; Werner, J; Yau, L; Zahradka, P1
Chen, T; Guo, Z; Ling, Q; Yu, Y1
Hirata, K; Kanazawa, H; Yoshikawa, J1
Davis, EA; Widdop, RE; Zwart, AS1
Akishita, M; Daviet, L; Dzau, VJ; Horiuchi, M; Ito, M; Lehtonen, JY1
De Paolis, P; Gigante, B; Natale, A; Piras, O; Porcellini, A; Volpe, M1
Audus, KL; Rose, JM1
Ardaillou, R1
Mendelsohn, FA; Ohishi, M; Zhuo, J1
Endemann, D; He, G; Li, JS; Schiffrin, EL; Touyz, RM1
Georgiev, V; Georgieva, D1
Dhalla, NS; Saward, L; Shao, Q; Zahradka, P1
Han, HJ; Koh, HJ; Park, SH1
Borges, AC; Paiva, TB; Prioste, RN; Shimuta, SI1
Anwar, M; Ibrahim, IN; Kadowitz, PJ; Kaye, AD; Nossaman, BD; Smith, DE1
Lew, WY; Yasuda, S1
Baum, M; Quan, A1
Nishimura, H; Qin, ZL; Yan, HQ1
Chevalier, RL; Thornhill, BA; Wolstenholme, JT1
Brosius, FC; Izumo, S; Malhotra, R; Sadoshima, J1
Deng, LY; He, G; Schiffrin, EL; Touyz, RM; Wu, XH1
Fujinaga, M; Hein, L; Hutchinson, HG; Pratt, RE1
Corvol, P; Gasc, JM; Hus-Citharel, A; Llorens-Cortes, C; Marchetti, J; Roques, B; Zini, S1
Diep, QN; Li, JS; Schiffrin, EL1
Henrion, D; Heymes, C; Lévy, BI; Loufrani, L; Matrougui, K1
Ardaillou, R; Chansel, D; Henrion, D; Levy, BI; Loufrani, L1
Côté, F; Do, TH; Gallo, JM; Gallo-Payet, N; Laflamme, L1
Cheung, PK; Saward, L; Wilson, DP; Zahradka, P1
Coba, MP; Gironacci, MM; Peña, C1
Lamparter, S; Sun, Y; Weber, KT1
Georgiev, V; Opitz, M1
Coviello, A; Peral de Bruno, M; Romano, L1
Arendshorst, WJ; Coffman, TM; Oliverio, MI; Ruan, X1
Kasahara, T; Kawano, H; Kimura, S; Kitamura, H; Kunieda, Y; Masuda, H; Nakagawa, K; Nakagawa, M; Nakahara, Y; Nishimura, H; Sawada, S; Sugano, T; Tsuji, H; Yano, S; Yoshizumi, M1
Carbini, LA; Nadal, JA; Nussbaum, JJ; Scicli, AG; Scicli, GM1
Damme, U; Daniel, WG; Garlichs, CD; Mügge, A; Plötze, K; Schmeisser, A; Zhang, H1
Dali-Youcef, N; Nemer, M; Paradis, FW; Paradis, P; Thibault, G1
Dixon, B; Rowe, BP1
Cody, RJ; Goetze, S; Graf, K; Hsueh, WA; Kawano, H; Kawano, Y; Law, RE; Schnee, J1
Adamy, C; Adnot, S; Chassagne, C; Dubois-Randé, JL; Eddahibi, S; Marotte, F; Rideau, D; Samuel, JL; Teiger, E1
De Paolis, P; Gigante, B; Giliberti, R; Lombardi, A; Porcellini, A; Rubattu, S; Savoia, C; Volpe, M1
Gutierez, CI; Israel, A; Sosa, B1
Chevalier, RL; Thornhill, BA; Yoo, KH1
De Paolis, P; Gigante, B; Panina, G; Piras, O; Rubattu, S; Savoia, C; Volpe, M1
Cierco, M; Israel, A; Sosa, B1
Henrion, D; Lévy, BI; Matrougui, K1
Arroyo, V; Bataller, R; Bosch, J; Garcia-Ramallo, E; Gasull, X; Ginès, P; Görbig, MN; Nicolás, JM; Rodés, J1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR1
Auger-Messier, M; Escher, E; Gosselin, MJ; Guillemette, G; Leclerc, PC; Leduc, R1
Cierco, M; Gutierrez, CI; Israel, A; Sosa-Canache, B1
Cho, KW; Kim, SH; Kim, SZ; Kim, YG; Park, JK1
Carroll, MA; Croft, KD; McGiff, JC; Sanchez-Mendoza, A1
Alvarez, A; Esplugues, JV; Issekutz, AC; Kubes, P; O'Connor, E; Piqueras, L; Sanz, MJ1
Min, L; Sim, MK; Xu, XG1
Bianciotti, L; Fernandez, B; Kadarian, C; Rodano, V; Rodriguez-Campos, M; Vatta, M1
Armando, I; Ciuffo, G; Egidy, G; Häuser, W; Hoe, KL; Inagami, T; Jöhren, O; Saavedra, JM; Sembonmatsu, T1
Duhault, J; Lonchampt, M; Pennel, L1
Chan, JY; Chan, SH; Lin, K1
Chen, Y; Dong, X; Fung, ML; Lam, SY; Leung, PS1
Ikegami, H; Suzuki, T; Yamada, T1
Carrier, GO; Catravas, JD; Dimitropoulou, C; Fuchs, L; White, RE; Zhang, H1
Brun, SR; da Luz, V; Fernandez, M; Marino-Neto, J; Paschoalini, MA1
Andrade, SP; Machado, RD; Santos, RA1
Frandsen, E; Ibsen, H; Jonassen, TE; Petersen, JS; Staahltoft, D; Worck, RH1
de Zeeuw, D; Filipeanu, CM; Henning, RH; Nelemans, A1
Lombard, JH; Weber, DS1
Breno, MC; Picarelli, ZP; Porto, CS1
Ma, CT; Yu, TZ1
Blanco, J; Egido, J; Lorenzo , O; Ruiz-Ortega, M; Rupérez, M1
Datté, JY; Gohlke, P; Pees, C; Ziegler, A1
Aizman, R; Celsi, G; Chen, M; Gerasev, A; Grahnquist, L1
Camara, AK; Osborn, J1
Brunette, MG; Charbonneau, A; Leclerc, M1
Gelband, CH; Posner, P; Sumners, C; Zhu, M1
Egido, J; Lorenzo, O; Ruiz-Ortega, M; Rupérez, M; Suzuki, Y1
Kramer, CM; Lee, S; Mankad, S; Sandberg, K; Yoo, SE1
Brailoiu, E; De Zeeuw, D; Filipeanu, CM; Henning, RH; Kok, JW; Nelemans, SA1
Fluharty, SJ; Heerding, JN; Hines, J; Yee, DK1
Burns, KD; Zimpelmann, J1
Bobrovskaya, L; Dunkley, PR; Leal, RB; Odell, A1
Bautista, R; Escalante, B; Hernández, J; Oyekan, A; Sánchez, A1
Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG1
Armando, I; Falcón-Neri, A; Häuser, W; Inagami, T; Jöhren, O; Saavedra, JM; Terrón, JA1
Elton, TS; Martin, MM; McDougall, JK; Victor, X; Zhao, X1
Cassis, LA; Daugherty, A; Manning, MW1
Butler, DG; Zhang, DH1
Bédard, S; Brochu, M; Sicotte, B; St-Louis, J1
Hayashi, M; Kuroda, M; Mifune, M; Nakaya, H; Saruta, T; Sasamura, H; Shimizu-Hirota, R1
Bica, RB; Caruso-Neves, C; Correa, JS; Lara, LS; Lopes, AG; Marques-Fernandes, MF; Sena, SL1
Collister, JP; Osborn, JW; Soucheray, SL1
Badzyńska, B; Dobrowolski, L; Grzelec-Mojzesowicz, M; Sadowski, J1
Brailoiu, E; de Zeeuw, D; Deelman, LE; Filipeanu, CM; Henning, RH; Nelemans, SA1
Carbini, LA; Nadal, JA; Scicli, AG; Scicli, GM1
Han, HJ; Park, SH1
Braszko, JJ1
Li, X; Papp, M; Uhal, BD; Wang, R; Zhuang, J1
Buczko, W; Chabielska, E; Kucharewicz, I; Matys, T; Pawlak, D; Rólkowski, R1
Burrell, JH; Gibson, KJ; Lumbers, ER; McMullen, JR1
Accorsi-Mendonça, D; Anselmo-Franci, JA; Corrêa, FM; de Oliveira, AM1
Cardarelli, MG; Downing, SW; McLaughlin, JS; Wei, C1
Ferguson, P; Grammatopoulos, T; Morris, K; Weyhenmeyer, J1
Fan, YP; Puri, RN; Rattan, S1
Carey, RM; De Gasparo, M; El-Kersh, MA; Siragy, HM; Webb, RL1
Accorsi-Mendonça, D; Anselmo-Franci, JA; Corrêa, FM; de Oliveira, AM; Paiva, TB1
Ding, G; Franki, N; Gibbons, N; Kapasi, AA; Kasinath, BS; Reddy, K; Singhal, PC1
Camargo, LA; Saad, WA; Santos, TA; Simões, S1
de Godoy, MA; de Oliveira, AM1
Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R1
Handelsman, CA; Pallone, TL; Rhinehart, K; Silldorff, EP1
Cowling, RT; Greenberg, BH; Gurantz, D; Peng, J; Tran, V1
Averill, DB; Brosnihan, KB; Chappell, MC; Diz, DI; Ferrario, CM; Nakamura, S1
Gopalakrishnan, V; Liu, P; Misurski, DA1
Hein, TW; Kuo, L; Wang, W; Zhang, C1
Hansmann, C; Hauser, P; Klingler, H; Mayer, G; Oberbauer, R; Schwarz, C; Weidekamm, C1
Bealer, SL; Crowley, WR1
Georgiev, V; Kambourova, T; Matsoukas, J; Pechlivanova, D; Tchekalarova, J1
Brännström, M; Matousek, M; Mikuni, M; Mitsube, K; Zackrisson, U1
Jarrott, B; Lawrence, AJ; Roulston, CL; Widdop, RE1
Chintalgattu, V; Katwa, LC; Nair, DM1
Camargo, LA; Saad, WA1
Bild, W; Boisteanu, CP; Haulica, I; Ionita, T; Mihaila, CN; Neagu, B1
Chen, SR; Li, DP; Pan, HL1
Bagi, EE; Fekete, E; Lénárd, L1
Chen, QH; Toney, GM1
Benndorf, R; Böger, RH; Ergün, S; Steenpass, A; Wieland, T1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Blanco-Colio, LM; Egido, J; Esteban, V; Lorenzo, O; Ruiz-Ortega, M; Rupérez, M1
Bräsen, JH; Budde, K; Dragun, D; Fritsche, L; Luft, FC; Neumayer, HH; Schönemann, C; Wallukat, G1
deChâtel, R; Földes, G; Ilves, M; Lakó-Futó, Z; Leskinen, H; Ruskoaho, H; Sármán, B; Skoumal, R; Szokodi, I; Tokola, H; Tóth, M; Vuolteenaho, O1
Ip, SP; Leung, PS; Tsang, SW1
Carlsson, PO; Lau, T; Leung, PS1
Averill, DB; Brosnihan, KB; Ferrario, CM; Gallagher, PE; Ishiyama, Y; Tallant, EA1
Carey, RM1
Hagiwara, Y; Kubo, T1
Burns, KD; Kumar, D; Robertson, S; Zimpelmann, J1
Cheng, CH; Leung, PS; Tsang, SW1
Hiyoshi, H; Okamoto, H; Takano, M; Yayama, K1
Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P1
Ingelfinger, JR; Moini, B; Zhang, SL1
Abi-Abib, R; Cardozo, FP; Caruso-Neves, C; De Souza, AM; Fernandes, MS; Fossari, RN; Lopes, AG; Miguel, NC; Pizzino, CP; Santos, DP1
de Godoy, MA; de Oliveira, AM; Rattan, S1
Andres, R; Ferguson, P; Kang, E; Orr, B; Schelman, WR; Weyhenmeyer, JA1
Du, JQ; Sun, CW; Tang, JS1
Avila-Casado, MC; Bautista, R; Coronel, I; Escalante, B; Romo, E; Soto, V; Vázquez, E; Villalón, CM1
Oberhauser, V; Rump, LC; Sellin, L; Stegbauer, J; Vonend, O1
Daniel, WG; Eskafi, S; Gabler, C; Garlichs, CD; Illmer, T; Lorenz, HM; Roerick, O; Schmeisser, A; Soehnlein, O; Strasser, R1
Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL1
El-Haddad, MA; Gayle, D; Ismail, Y; Ross, MG1
Chan, JS; Fantus, IG; Filep, JG; Fustier, P; Hamet, P; Hsieh, TJ; Ingelfinger, JR; Tang, SS; Wei, CC; Zhang, SL1
Assunção-Miranda, I; Costa-Sarmento, G; Guilherme, AL; Oliveira, MM; Reis-Silva, C; Vieyra, A1
Raizada, MK; Sellers, KW; Sumners, C; Sun, C1
Ferrario, CM; Gallagher, PE; Richmond, RS; Strawn, WB; Tallant, EA1
Ito, Y; Mabuchi, H; Oda, N; Takeda, Y; Usukura, M; Yoneda, T1
Lachowicz-Ochedalska, A; Rebas, E1
Chan, LY; Choy, CB; Lai, KN; Leung, JC; Tang, SC1
Han, HJ; Heo, JS; Lee, YJ1
Galindo, M; Gutierrez-Cañas, I; Pablos, JL; Palao, G; Ramirez, JC; Santiago, B1
Chan, JY; Chan, SH; Hsu, KS; Huang, CC; Ou, CC; Wang, LL1
Alenina, N; Almeida, AP; Bader, M; Castro, CH; Ferreira, AJ; Santos, RA1
Chappell, MC; Ferrario, CM; Gallagher, PE; Tallant, EA1
Inoue, A; Ishiguro, S; Liao, JK; Miyamoto, A; Nishio, A; Wada, R1
Hsieh, PS1
Carretero, OA; Li, XC; Navar, LG; Zhuo, JL1
Flannery, PJ; Spurney, RF1
Caron, N; Flamion, B; Imig, JD; Joly, E; Kramp, R; Michel, A; Seqqat, R1
Lee, J; Mao, C; Morrissey, P; Shi, L; Wu, J; Xu, Z1
Bevilaqua, LR; Bonini, JS; Cammarota, M; Izquierdo, I; Kerr, DS; Medina, JH; Zinn, CG1
Handa, RK1
Edebo, A; Ewert, S; Fändriks, L; Johnsson, E; Olbers, T; Spak, E1
Kaakinen, R; Kovanen, PT; Lindstedt, KA; Oörni, K; Sneck, M1
de Godoy, MA; Rattan, S1
Choi, MR; Correa, AH; del Valle Turco, V; Fernández, BE; Garcia, FA1
Comiter, CV; Escobar, C; Phull, H; Purves, T; Salkini, M1
Georgiev, V; Tchekalarova, J1
Gao, Y; Grobe, JL; Katovich, MJ; Li, H; Raizada, MK; Sumners, C1
Gao, GD; Jiang, XY; Lin, YX; Wang, XF; Wang, YW; Yang, YB1
Arafat, HA; Chipitsyna, G; Gong, Q; Gray, CF; Haroon, Y; Kamer, E1
Karamyan, VT; Speth, RC2
Huang, Y; Lu, LM; Shao, Y; Yao, T; Zhou, L1
Gironacci, MM; Peña, C; Polizio, AH; Tomaro, ML1
Chen, P; Edwards, PA; Guo, AM; Scicli, AG; Trick, G1
Gao, GD; Lin, YX; Liu, JJ; Xu, X; Zhou, J1
Grammatopoulos, TN; Hyman, BT; Outeiro, TF; Standaert, DG1
Goda, M; Hobara, N; Kawasaki, H; Kitamura, Y; Mio, M; Takatori, S; Yoshida, N1
Braszko, JJ; Holownia, A1
Fernandes, R; Ferreira, R; Gonçalves, PB; Moraes, JF; Oliveira, JF1
Anton, L; Brosnihan, KB; Merrill, DC; Neves, LA1
Anandanadesan, R; Arafat, HA; Chipitsyna, G; Gong, Q; Witkiewicz, A; Yeo, CJ1
Grabowski, EF; Ingelfinger, JR; Kushak, RI; Nestoridi, E; Tsukurov, O1
Gao, GD; Jiang, XY1
Huang, X; Longo, LD; Xiao, D; Xu, Z; Yang, S; Zhang, L1
Badimon, L; Costales, P; Huesca-Gómez, C; Llorente-Cortés, V; Sendra, J1
Lamb, FS; Miller, FJ; Roghair, RD; Scholz, TD; Segar, JL1
Lee, JH; Ragolia, L; Xia, S1
Clarke, D; Medow, MS; Raghunath, N; Stewart, JM; Taneja, I1
Campbell, WB; Cui, L; Gauthier, KM; Nithipatikom, K; Zhang, DX1
Ciuffo, GM; Forneris, ML; Fuentes, LB; Sánchez, SI; Seltzer, AM1
Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A1
Karamyan, VT; Speth, RC; Stockmeier, CA1
Costa, CA; Criddle, DN; Espinoza, LA; Marins de Carvalho, LC; Ognibene, DT; Oliveira, PR; Resende, AC; Soares de Moura, R; Tano, T1
Chen, W; Deans, T; Gratze, P; Guzik, TJ; Harrison, DG; Hoch, NE; Maalouf, SA; Weyand, C1
Feng, Y; Hickman, PJ; Lazartigues, E; Obr, TD; Xia, H1
Falone, AE; Khalil, RA; Koledova, VV; Qiao, X; Stennett, AK1
Anton, L; Brosnihan, KB; Corthorn, J; Diz, DI; Gallagher, PE; Gruver, C; Merrill, DC; Moorefield, C; Neves, LA; Stovall, K; Valdes, G1
Arce, ME; Ciuffo, GM; Fuentes, LB; Sánchez, SI1
Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Helander, HF; Jönson, C; Spak, E1
Chaudhary, AK; Ely, D; Gopinathannair, R; Martins, JB; Xing, D; Zheng, W1
Calò, LA; D'Angelo, A; Davis, PA; Mormino, P; Pagnin, E; Pessina, AC; Schiavo, S1
Cecconello, AL; Lucion, AB; Raineki, C; Sanvitto, GL; Sebben, V1
Au, LS; Chen, C; Cheng, Q; Chu, KY; Kwan, YW; Leung, PS; Motin, L; Seto, SW; Tuo, Y1
Chappell, MC; Diz, DI; Gwathmey, TM; Pendergrass, KD; Reid, SD; Rose, JC1
Barrett, EJ; Cao, W; Carey, RM; Chai, W; Liu, J; Liu, Z; Wang, W1
Anand-Srivastava, MB; Gomez Sandoval, YH; Lévesque, LO1
Fogo, AB; Han, JY; Kon, V; Ma, LJ; Naito, T; Tang, Y; Yang, H; Zuo, Y1
Chen, CM; Hung, CL; Lang, YD; Wang, LF; Wu, TY1
Cai, L; Chen, X; Fu, S; Sui, G; Yang, Y; Zhao, Y1
Guo, C; Guo, RW; Liu, H; Qi, F; Wang, XM; Yang, LX; Ye, JS1
Durand, MJ; Lombard, JH; Raffai, G; Weinberg, BD1
Barnes, JL; Cavaglieri, Rde C; Day, RT; Feliers, D; Kasinath, BS; Lee, MJ; Mantravadi, V; Tabatabaimir, H1
Carretero, OA; D'Ambrosio, MA; Garvin, JL; Ren, Y1
Arzola, J; De Jesús, S; del Rosario Garrido, M; Israel, A; Matos, MG; Pastorello, M; Silva, J; Varela, M; Zavala, LE1
Goda, M; Hashikawa, N; Hobara, N; Kawasaki, H; Yoshida, N1
Barreto-Chaves, ML; Carrillo-Sepúlveda, MA; Chies, AB; da Silva, OG; Rossignoli, Pde S1
Chan, YC; Leung, PS1
Hassid, A; Pu, Q; Thakran, S; Zhuang, D1
da Silva, AQ; Fontes, MA; Kanagy, NL1
Gao, S; Kim, JH; Kim, SH; Oh, YB; Park, WH; Shah, A1
Chou, PC; Hsiao, PJ; Hsieh, TJ; Hung, WW; Lin, KD; Lin, T; Shin, SJ1
Brailoiu, E; Brailoiu, GC; Deliu, E; Motoc, D; Tica, AA1
Louis, S; Saward, L; Zahradka, P1
Clark, MA; Nguyen, C; Tran, H1
Andreozzi, F; Laino, I; Martino, F; Musca, D; Perticone, F; Perticone, M; Presta, I; Sciacqua, A; Sesti, G; Tassone, EJ1
Acet, A; Ozer, MK; Parlakpinar, H1
Alenina, N; Bader, M; de Oliveira, ML; Dos Santos, RA; Fontes, WR; Lazaroni, TL; Moraes, MF; Pereira, GS; Raslan, AC1
Chitravanshi, VC; Proddutur, A; Sapru, HN1
Collino, M; Fantozzi, R; Miglio, G; Rattazzi, L; Rosa, AC1
Chang, CC; Chuang, CL; Huang, HC; Lee, FY; Lee, JY; Lee, SD; Lin, HC; Teng, TH; Wang, SS1
Huang, Y; Lu, L; Ni, J; Wang, J; Wang, Z; Xue, H; Yao, T; Yu, C; Yuan, P; Zhou, L1
Hashimoto, T; Ichiki, T; Kamiharaguchi, A; Kitamoto, S; Matsuura, H; Miyazaki, R; Sunagawa, K; Tokunou, T1
Axelband, F; Costa-Neto, CM; Dias, J; Ferrão, FM; Lara, LS; Miranda, F; Reis, RI; Vieyra, A1
Kunert-Radek, J; Lawnicka, H; Mucha, S; Pawlikowski, M; Ptasinska-Wnuk, D; Stepien, H1
Arakawa, H; Kawabe, K; Sapru, HN1
Garvin, JL; Hong, NJ1
Anand-Srivastava, MB; Li, Y1
Domińska, K; Lachowicz-Ochędalska, A; Ochędalski, T; Piastowska-Ciesielska, AW1
Cao, L; Fang, Q; Li, S; Liu, Y; Mao, C; Shi, A; Wu, L; Xu, Z; Zhou, A; Zhu, H1
Iinuma, T; Kamio, N; Kawato, T; Maeno, M; Morita, T; Nakai, K; Zhao, N1
Chen, Q; Chen, T; Wu, Y; Xiao, Q; Yan, H; Zhang, L; Zheng, X; Zhou, Y; Zhu, J; Zhu, L1
An, SJ; Chai, XQ; Gao, WJ; Liu, P; Lu, HG; Shao, TM1
Cha, SA; Gao, S; Kang, KP; Kim, SH; Oh, YB; Park, BM1
Aoyama, M; Arai, T; Takata, Y; Watanabe, A; Yamaki, F1
Almeida, JF; Alves, GM; Castro, CH; Colugnati, DB; Ferreira, AJ; Macedo, LM; Mendes, EP; Porto, JE; Santos, RA; Sobrinho, DB; Souza, ÁP; Vêncio, EF1
Abdulla, MH; Johns, EJ2
Cha, SA; Gao, S; Kim, SH; Park, BH; Park, BM; Park, WH1
Cassis, LA; Dwoskin, LP; Horton, DB; Narayanaswami, V; Somkuwar, SS1
Ishikawa, M; Kanno, S; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yaoita, F; Yomogida, S1
Buikema, H; Faas, MM; Henning, RH; Plösch, T; van Buiten, A; van der Graaf, AM; Wiegman, MJ; Zeeman, GG1
Clark, MA; Haspula, D; Kandalam, U; Sarmiento, N1
Chen, CC; Ho, LT; Hsu, YP; Juan, CC; Kwok, CF; Lin, YJ; Shih, KC1
Bądzyńska, B; Kompanowska-Jezierska, E; Lipkowski, AW; Sadowski, J1
Castillo, EF; Castillo, MC; Guevara, G; López, JS; López, P; López, RM1
Mansoori, A; Nematbakhsh, M; Oryan, S2
Cai, M; Cao, B; Chen, W; Duan, Y; Gu, H; Jiang, C; Lai, C; Penninger, JM; Wang, W; Wang, X; Yang, P; Yang, X; Zhang, L; Zhang, S; Zhao, Z; Zhen, W1
Cantilena, B; Cozzolino, C; Esposito, MT; Lombardo, B; Parisi, S; Passaro, F; Pastore, L; Querques, F; Russo, T1
An, SJ; Fu, JQ; Jiao, Z; Li, X; Liu, P; Lu, HG; Shao, TM; Wang, ZJ1
Jiang, X; Ning, Q; Zhang, F1
Burnett, CM; Claflin, KE; Grobe, JL; Kahn, MZ; Littlejohn, NK; Lutter, ML; Morales-Santiago, FI; Ni, J; Pearson, NA; Voong, S; Weidemann, BJ1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G1
Clark, MA; Gowrisankar, YV1
Arnold, MR; Forte, BL; Hay, M; Largent-Milnes, TM; Slosky, LM; Staatz, WD; Vanderah, TW; Zhang, H1
Burghi, V; Cervino, IA; Dominici, FP; Mazziotta, L; Miquet, JG; Muñoz, MC; Quiroga, DT1
Khanmoradi, M; Nasimi, A1
Fabris, D; Fachim, HA; Genaro, K; Prado, WA1
Cao, T; Fan, Y; Hu, B; Jia, R; Lu, Y; Luo, X; Qiao, H; Sun, B; Wang, N; Yan, J1
Duan, XP; Gao, ZX; Gu, R; Lin, DH; Su, XT; Wang, MX; Wang, WH; Wu, P1
Biojone, C; Casarotto, PC; Castrén, E; Diniz, CRAF; Fred, SM; Joca, SRL1
Chen, Q; Deng, W; Karnik, SS; Si, W; Wang, QK; Xiao, Y; Xie, W; Xu, C1
Jiang, X; Li, SH; Li, ZH; Liang, JX; Liao, X; Liu, HW; Wu, F; Wu, YD; Xu, Y; Yan, JX1
Cai, W; Cai, X; Gao, F; Huang, D; Lan, J; Shi, G; Xu, H; Zhang, Y; Zheng, F; Zhong, S1
Arthur, E; Chen, J; Janda, A; Kwartler, CS; Milewicz, DM; Peters, AM; Wang, S; Zhou, P; Zhou, Z1
Georgiev, T; Hadzhibozheva, P; Kalfin, R; Tolekova, A1
Lin, X; Lu, J; Shi, J; Tian, M; Wu, L; Zhang, Y1
Bulut, H; Demirci Tansel, C; Gurel Gurevin, E; Kilic, A; Meral, I; Usta, C; Ustunova, S1
Costa-Ferreira, W; Crestani, CC; Gomes-de-Souza, L1
Chen, X; Fan, X; Gao, Q; Han, B; Li, M; Li, X; Lu, L; Sun, M; Tang, J; Tao, J; Xu, Z; Zhang, M; Zhang, Y1
Cui, H; Liang, H; Lv, J; Wang, H; Wang, M; Wang, S; Ye, F; Zheng, Y; Zhu, Y1
Fermigier, A; Hamel, E; Lacalle-Aurioles, M; Royea, J; Trigiani, LJ1
Costa-Ferreira, W; Crestani, CC; Marchi-Coelho, C; Moreno-Santos, B1
Ge, J; Jiang, H; Su, Y; Wang, J; Wu, J; Yu, Y; Zhang, B; Zhang, L; Zou, Y1

Reviews

3 review(s) available for losartan and pd 123319

ArticleYear
Pharmacology of angiotensin II receptors in the kidney.
    Kidney international, 1994, Volume: 46, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Humans; Imidazoles; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Species Specificity; Tetrazoles; Tissue Distribution

1994
Angiotensin II receptors.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium; Humans; Imidazoles; Kidney; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1999
[Regeneration of perivascular nerve and role of angiotensin receptors].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcitonin Gene-Related Peptide; Humans; Imidazoles; Losartan; Male; Mesenteric Arteries; Nerve Growth Factor; Nerve Regeneration; Neuropeptide Y; Peripheral Nerve Injuries; Peripheral Nerves; Phenol; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Stimulation, Chemical

2010

Trials

1 trial(s) available for losartan and pd 123319

ArticleYear
Intradermal angiotensin II administration attenuates the local cutaneous vasodilator heating response.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:1

    Topics: Administration, Cutaneous; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hot Temperature; Humans; Imidazoles; Infusions, Parenteral; Losartan; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyridines; Receptor, Angiotensin, Type 2; Regional Blood Flow; Skin; Skin Temperature; Vasoconstrictor Agents; Vasodilation

2008

Other Studies

469 other study(ies) available for losartan and pd 123319

ArticleYear
Angiotensin II receptor subtypes in rat renal preglomerular vessels.
    Receptor, 1992,Winter, Volume: 2, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Kidney; Kidney Glomerulus; Losartan; Microcirculation; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1992
Angiotensin-II acts via the type 1 receptor to inhibit 17 alpha-hydroxylase cytochrome P450 expression in ovine adrenocortical cells.
    Endocrinology, 1992, Volume: 130, Issue:6

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; Kinetics; Losartan; Phosphoric Diester Hydrolases; Pyridines; Receptors, Angiotensin; RNA, Messenger; Sheep; Steroid 17-alpha-Hydroxylase; Tetrazoles; Zona Fasciculata; Zona Reticularis

1992
A newly found angiotensin II receptor subtype mediates cyclic GMP formation in differentiated Neuro-2A cells.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Binding Sites; Biphenyl Compounds; Cell Differentiation; Cyclic GMP; Imidazoles; Losartan; Neuroblastoma; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured

1992
Effects of angiotensin II and nonpeptide receptor antagonists on transduction pathways in rat proximal tubule.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cyclic AMP; Imidazoles; Inositol Phosphates; Kidney Tubules, Proximal; Losartan; Male; Osmolar Concentration; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles

1992
Angiotensin II increases proto-oncogene expression and phosphoinositide turnover in vascular smooth muscle cells via the angiotensin II AT1 receptor.
    Journal of hypertension, 1992, Volume: 10, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Gene Expression Regulation; Genes, fos; Imidazoles; Losartan; Muscle, Smooth, Vascular; Phosphatidylinositols; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1992
Angiotensin II receptor subtypes in cultured rat renal mesangial cells.
    The American journal of physiology, 1992, Volume: 263, Issue:3 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cells, Cultured; Glomerular Mesangium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Losartan; Pertussis Toxin; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Virulence Factors, Bordetella

1992
Characterization of glomerular angiotensin II receptor subtypes.
    Receptor, 1992,Fall, Volume: 2, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Kinetics; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1992
Inhibition of the haemodynamic effects of angiotensin II in conscious rats by AT2-receptor antagonists given after the AT1-receptor antagonist, EXP 3174.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Pyridines; Rats; Regional Blood Flow; Tetrazoles

1992
Modulation of net outward current in cultured neurons by angiotensin II: involvement of AT1 and AT2 receptors.
    Brain research, 1992, May-15, Volume: 580, Issue:1-2

    Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Brain Stem; Cells, Cultured; Hypothalamus; Imidazoles; Losartan; Membrane Potentials; Neurons; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles

1992
Renal hemodynamic and excretory responses to PD 123319 and losartan, nonpeptide AT1 and AT2 subtype-specific angiotensin II ligands.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Pyridines; Renal Circulation; Saralasin; Tetrazoles

1992
Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa.
    Molecular pharmacology, 1992, Volume: 41, Issue:4

    Topics: Allosteric Regulation; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cattle; Cells, Cultured; Imidazoles; Losartan; Microsomes; Polyvinyls; Pyridines; Receptors, Angiotensin; Signal Transduction; Substrate Specificity; Tetrazoles; Zona Glomerulosa

1992
Angiotensin II receptor subtypes play opposite roles in regulating phosphatidylinositol hydrolysis in rat skin slices.
    Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Hydrolysis; Imidazoles; In Vitro Techniques; Inositol Phosphates; Kinetics; Losartan; Male; Phosphatidylinositols; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Skin; Tetrazoles

1992
Angiotensin-II activation of cAMP and corticosterone production in bovine adrenocortical cells: effects of nonpeptide angiotensin-II antagonists.
    Molecular and cellular endocrinology, 1991, Volume: 81, Issue:1-3

    Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cattle; Corticosterone; Cyclic AMP; Imidazoles; Losartan; Pyridines; Saralasin; Tetrazoles

1991
Protein tyrosine phosphatase inhibition by angiotensin II in rat pheochromocytoma cells through type 2 receptor, AT2.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Chromatography, Affinity; Guanosine Diphosphate; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pertussis Toxin; Pheochromocytoma; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Thionucleotides; Tyrosine; Virulence Factors, Bordetella

1994
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine

1995
Tissue- and subtype-specific modulation of angiotensin II receptors by chronic treatment with cyclosporin A, angiotensin-converting enzyme inhibitors and AT1 antagonists.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Administration, Oral; Adrenal Cortex; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cyclosporine; Down-Regulation; Drug Interactions; Imidazoles; Kidney; Lisinopril; Liver; Losartan; Male; Pyridines; Quinolines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Up-Regulation

1995
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
    FEBS letters, 1995, Oct-16, Volume: 373, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1995
Central administration of PD 123319 or EXP-3174 inhibits effects of angiotensin II.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 2

    Topics: Angiotensin II; Animals; Brain; Hemodynamics; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred Strains; Substance P; Tetrazoles

1993
Central effect of angiotensin III on caudal hypoglossal neurons in rats.
    The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 2

    Topics: Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Brain; Carbachol; Electrophysiology; Hypoglossal Nerve; Imidazoles; Injections, Intraventricular; Losartan; Male; Neurons; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saline Solution, Hypertonic; Tetrazoles

1995
Evidence for the involvement of different receptor subtypes in the pre- and postjunctional actions of angiotensin II at rat sympathetic neuroeffector sites.
    British journal of pharmacology, 1995, Volume: 114, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Electric Stimulation; Female; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Neuroeffector Junction; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Vas Deferens

1995
Angiotensin II regulates H(+)-ATPase activity in rat cortical collecting duct.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: Adenosine Diphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Biphenyl Compounds; Collagenases; Ethylmaleimide; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Kidney Cortex; Kidney Tubules, Collecting; Losartan; Macrolides; Proton-Translocating ATPases; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles

1994
Evidence for an antagonistic angiotensin II/alpha 2-adrenoceptor interaction in the nucleus tractus solitarii.
    European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Imidazoles; Losartan; Male; Microinjections; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Angiotensin; Software; Solitary Nucleus; Specific Pathogen-Free Organisms; Tetrazoles

1994
Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:4

    Topics: Adsorption; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Peptide Fragments; Perfusion; Permeability; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles

1994
Analysis of responses to ANG IV: effects of PD-123319 and DuP-753 in the pulmonary circulation of the rat.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Hypoxia; Imidazoles; Losartan; Male; Meclofenamic Acid; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction

1995
Characterization of angiotensin II receptor type 2 during differentiation and apoptosis of rat ovarian cultured granulosa cells.
    Biochemical and biophysical research communications, 1995, Feb-15, Volume: 207, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; DNA; Female; Follicle Stimulating Hormone; Granulosa Cells; Imidazoles; Kinetics; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1995
Angiotensin II AT1 receptor mediated contraction of the perfused rat cerebral artery.
    Neuroreport, 1994, Nov-21, Volume: 5, Issue:17

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Arteries; Imidazoles; In Vitro Techniques; Losartan; Male; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1994
Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diuresis; Glomerular Filtration Rate; Imidazoles; Losartan; Male; Natriuresis; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles

1995
Age-related changes in angiotensin II-stimulated vascular contraction and inositol phosphate accumulation in Fischer 344 rats.
    Mechanisms of ageing and development, 1994, Oct-20, Volume: 76, Issue:2-3

    Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arteries; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Inositol Phosphates; Losartan; Male; Pyridines; Rats; Rats, Inbred F344; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1994
Angiotensin AT2 receptor stimulation increases survival in gerbils with abrupt unilateral carotid ligation.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:6

    Topics: Animals; Biphenyl Compounds; Brain Ischemia; Carotid Arteries; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Gerbillinae; Imidazoles; Ligation; Losartan; Male; Pyridines; Receptors, Angiotensin; Regional Blood Flow; Survival Analysis; Tetrazoles

1994
Cloning of a rabbit kidney cortex AT1 angiotensin II receptor that is present in proximal tubule epithelium.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; Blotting, Northern; Blotting, Southern; Cells, Cultured; Cloning, Molecular; DNA; Epithelial Cells; Epithelium; Imidazoles; Iodine Radioisotopes; Kidney Tubules, Proximal; Losartan; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Pyridines; Rabbits; Receptors, Angiotensin; Sequence Homology, Nucleic Acid; Tetrazoles; Transfection

1993
Effects of angiotensin II AT1- or AT2-receptor antagonists on drinking evoked by angiotensin II or water deprivation in rats.
    Brain research, 1994, Jun-13, Volume: 648, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drinking; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Brattleboro; Tetrazoles; Water Deprivation

1994
Activation of AT1 angiotensin receptors induces DNA synthesis in a rat intestinal epithelial (RIE-1) cell line.
    The Biochemical journal, 1994, Sep-15, Volume: 302 ( Pt 3)

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; Blotting, Northern; Calcium; Cell Division; Cell Line; DNA; Enzyme Activation; Hydrolysis; Imidazoles; Intestinal Mucosa; Intestines; Losartan; Molecular Sequence Data; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1994
Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system.
    European journal of pharmacology, 1994, Jun-23, Volume: 259, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Vascular Resistance

1994
Angiotensin II AT2 receptor stimulation increases cerebrovascular resistance during hemorrhagic hypotension in rats.
    Regulatory peptides, 1994, Jun-16, Volume: 52, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Gas Analysis; Blood Pressure; Cerebral Cortex; Cerebral Hemorrhage; Dose-Response Relationship, Drug; Hypotension; Imidazoles; Infusions, Intravenous; Injections, Intravenous; Laser-Doppler Flowmetry; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tetrazoles; Vascular Resistance

1994
Rabbit renal epithelial angiotensin II receptors.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Dose-Response Relationship, Drug; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Iodine Radioisotopes; Kidney Cortex; Kinetics; Losartan; Male; Microvilli; Oligopeptides; Pyridines; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles

1994
Novel angiotensin receptor subtypes in fowl.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Blood Pressure; Cell Membrane; Chickens; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Receptors, Angiotensin; Reserpine; Tetrazoles

1994
Human cardiac fibroblasts express an angiotensin receptor with unusual binding characteristics which is coupled to cellular proliferation.
    Biochemical and biophysical research communications, 1994, Nov-15, Volume: 204, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Heart Failure; Humans; Imidazoles; Kinetics; Losartan; Myocardium; Pyridines; Radioligand Assay; Receptors, Angiotensin; Tetrazoles

1994
Angiotensin II binding activity in cultured porcine arterial endothelial cells.
    Biochemical pharmacology, 1994, Nov-16, Volume: 48, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding Sites; Biphenyl Compounds; Cells, Cultured; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Swine; Tetrazoles

1994
Distribution of angiotensin II receptors in rat and human adipocytes.
    Journal of lipid research, 1994, Volume: 35, Issue:8

    Topics: Adipocytes; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Epididymis; Humans; Imidazoles; Losartan; Male; Mesentery; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Retroperitoneal Space; Tetrazoles

1994
Role of angiotensin receptor subtypes in the response of rabbit brain arterioles to angiotensin.
    Stroke, 1994, Volume: 25, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Biphenyl Compounds; Brain; Cerebrovascular Circulation; Imidazoles; Losartan; Male; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Vasodilation

1994
Angiotensins induce the release of prostacyclin from rabbit vas deferens: evidence for receptor heterogeneity.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Epoprostenol; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Vas Deferens

1994
Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts.
    The American journal of physiology, 1994, Volume: 267, Issue:2 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cardiomegaly; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Reference Values; Tetrazoles; Tissue Distribution

1994
AT1 receptor characteristics of angiotensin analogue binding in human synovium.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Arthritis, Rheumatoid; Autoradiography; Biphenyl Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Imidazoles; Immunohistochemistry; In Vitro Techniques; Iodine Radioisotopes; Ligands; Losartan; Male; Middle Aged; Osteoarthritis; Pyridines; Receptors, Angiotensin; Synovial Fluid; Tetrazoles

1994
Effects of angiotensin II and angiotensin-(1-7) on the release of [3H]norepinephrine from rat atria.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Interactions; Electric Stimulation; Female; Heart; Heart Atria; Imidazoles; Losartan; Myocardium; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles

1994
Comparison of fos-like immunoreactivity induced in rat brain by central injection of angiotensin II and carbachol.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Brain; Carbachol; Imidazoles; Immunohistochemistry; Injections, Intraventricular; Losartan; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Tetrazoles

1994
Stimulatory effect of angiotensin II on the proliferation of mouse spleen lymphocytes in vitro is mediated via both types of angiotensin II receptors.
    Biochemical and biophysical research communications, 1994, Feb-15, Volume: 198, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Imidazoles; Losartan; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Pyridines; Receptors, Angiotensin; Spleen; Tetrazoles; Thymidine

1994
Role of angiotensin AT1 receptor in the cardiovascular response to footshock.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Electroshock; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1994
Effects of LHRH and ANG II on prolactin stimulation are mediated by hypophysial AT1 receptor subtype.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Gonadotropin-Releasing Hormone; Imidazoles; In Vitro Techniques; Losartan; Perfusion; Pituitary Gland; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1994
Ontogeny of angiotensin-II-induced prolactin release in vivo and in vitro in female and male rats.
    Neuroendocrinology, 1994, Volume: 59, Issue:1

    Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Losartan; Male; Pituitary Gland; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors

1994
Involvement of angiotensin receptor subtypes in osmotically induced release of vasopressin.
    Brain research, 1994, Feb-21, Volume: 637, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saline Solution, Hypertonic; Tetrazoles

1994
Effects of angiotensin receptor subtype inhibitors on plasma angiotensin clearance.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Losartan; Male; Metabolic Clearance Rate; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles

1994
The reduction in alcohol drinking by peripherally injected angiotensin II is selectively mediated by the AT1 receptor subtype.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Alcohol Drinking; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drinking; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles

1994
Brain angiotensin AT-2 receptor antagonism and water intake.
    Brain research bulletin, 1993, Volume: 32, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Carbachol; Cerebral Ventricles; Drinking Behavior; Imidazoles; Injections, Intraventricular; Isoproterenol; Losartan; Male; Models, Neurological; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles

1993
Human aortic smooth muscle cells containing angiotensin II type 1 receptors.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Calcium; Cells, Cultured; Humans; Imidazoles; Losartan; Membranes; Muscle, Smooth, Vascular; Pyridines; Receptors, Angiotensin; Tetrazoles

1993
Angiotensin II AT2 receptor stimulation extends the upper limit of cerebral blood flow autoregulation: agonist effects of CGP 42112 and PD 123319.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Imidazoles; Injections, Intravenous; Losartan; Male; Oligopeptides; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1994
Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Potassium; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles; Vascular Resistance

1993
Angiotensin receptor sites in renal vasculature of rats developing genetic hypertension.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Blood Vessels; Hemodynamics; Hypertension; Imidazoles; Losartan; Microcirculation; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasoconstriction

1993
Segmental differences in angiotensin receptor subtypes in interlobular artery of hydronephrotic rat kidneys.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Hydronephrosis; Imidazoles; In Vitro Techniques; Losartan; Male; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasoconstriction

1993
Angiotensin II receptor subtypes and biological responses in the rat heart.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:11

    Topics: Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Autoradiography; Biphenyl Compounds; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Heart Atria; Heart Ventricles; Imidazoles; Inositol Phosphates; Losartan; Pyridines; Rats; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles

1993
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
    Experimental physiology, 1993, Volume: 78, Issue:6

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst

1993
Angiotensin II receptors in the rat urinary bladder smooth muscle: type 1 subtype receptors mediate contractile responses.
    The Journal of urology, 1993, Volume: 150, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Urinary Bladder

1993
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1993
Pharmacological characteristics of the positive inotropic effect of angiotensin II in the rabbit ventricular myocardium.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bupranolol; Heart Ventricles; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Prazosin; Pyridines; Rabbits; Saralasin; Tetrazoles

1993
Angiotensin II responsiveness of rat paraventricular and subfornical organ neurons in vitro.
    Neuroscience, 1993, Volume: 55, Issue:1

    Topics: Action Potentials; Angiotensin II; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Neurons; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Subfornical Organ; Synaptic Transmission; Tetrazoles

1993
Angiotensin II receptor subtypes on adrenal adenoma in primary hyperaldosteronism.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 4, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Humans; Hyperaldosteronism; Imidazoles; Losartan; Male; Middle Aged; Pyridines; Receptors, Angiotensin; Tetrazoles

1993
The type 1 angiotensin-II receptor mediates intracellular calcium mobilization in rat luteal cells.
    Endocrinology, 1993, Volume: 133, Issue:4

    Topics: Adenosine Triphosphatases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Biphenyl Compounds; Calcium; Corpus Luteum; Culture Media; Dinoprost; Endoplasmic Reticulum; Female; Imidazoles; Intracellular Membranes; Losartan; Osmolar Concentration; Pyridines; Rats; Receptors, Angiotensin; Terpenes; Tetrazoles; Thapsigargin

1993
Nonpeptide angiotensin AT1 and AT2 receptor ligands modulate the upper limit of cerebral blood flow autoregulation in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebrovascular Circulation; Homeostasis; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1993
Distinct signal transduction pathways for angiotensin-II in guinea pig gastric smooth muscle: differential blockade by indomethacin and tyrosine kinase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Calcium; Catechols; Cyclohexanones; Dose-Response Relationship, Drug; Epidermal Growth Factor; Genistein; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Losartan; Male; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyridines; Quinacrine; Signal Transduction; Stomach; Tetrazoles; Tyrphostins

1993
Effect of nonpeptide angiotensin AT-1 and AT-2 antagonists on isoproterenol-induced renin release.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Injections, Intraventricular; Isoproterenol; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles

1993
Functional role of brain AT1 and AT2 receptors in the central angiotensin II pressor response.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Brain; Chlorisondamine; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles

1993
Signal transduction mediated by angiotensin II receptor subtypes expressed in rat renal mesangial cells.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cell Division; Cells, Cultured; Glomerular Mesangium; Imidazoles; Losartan; Oligopeptides; Protein Biosynthesis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1993
Regulated expression of angiotensin II (AT2) binding sites in R3T3 cells.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; 3T3 Cells; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bombesin; Cell Division; Fibroblast Growth Factor 2; Imidazoles; Losartan; Mice; Mitogens; Pyridines; Receptors, Angiotensin; Saralasin; Tetrazoles; Up-Regulation

1993
Role of AT1 receptors in the resetting of the baroreflex control of heart rate by angiotensin II in the rabbit.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Heart; Heart Rate; Imidazoles; Losartan; Male; Pressoreceptors; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles

1993
Angiotensin AT1 receptors mediate a positive inotropic effect of angiotensin II in guinea pig atria.
    European journal of pharmacology, 1993, Mar-15, Volume: 245, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Losartan; Myocardial Contraction; Pyridines; Radiography; Receptors, Angiotensin; Tetrazoles

1993
Functional roles of brain AT1 and AT2 receptors in the central angiotensin II pressor response in conscious young spontaneously hypertensive rats.
    Brain research. Developmental brain research, 1993, Feb-19, Volume: 71, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Disease Models, Animal; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Vasopressins

1993
Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 2

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin; Tetrazoles

1993
Effects of des-Asp-angiotensin I on the electrically stimulated contraction of the rabbit pulmonary artery.
    European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2

    Topics: Angiotensin I; Animals; Antihypertensive Agents; Biphenyl Compounds; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pulmonary Artery; Pyridines; Rabbits; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents

1995
The subtype-2 (AT2) angiotensin receptor regulates renal cyclic guanosine 3', 5'-monophosphate and AT1 receptor-mediated prostaglandin E2 production in conscious rats.
    The Journal of clinical investigation, 1996, Apr-15, Volume: 97, Issue:8

    Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Cyclic AMP; Dinoprostone; Extracellular Space; Female; Imidazoles; Kidney; Kinetics; Losartan; Microdialysis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reference Values; Sodium, Dietary; Tetrazoles; Time Factors

1996
Cyclic adenosine 3',5'-monophosphate-independent regulation of cytosolic calcium in Sertoli cells.
    Endocrinology, 1996, Volume: 137, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cyclic AMP; Cytosol; Dinoprost; Enzyme Inhibitors; Imidazoles; Isoquinolines; Kinetics; Losartan; Male; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Sertoli Cells; Sulfonamides; Terpenes; Tetrazoles; Thapsigargin; Vasopressins

1996
Angiotensin II induces TIMP-1 production in rat heart endothelial cells.
    Biochimica et biophysica acta, 1996, May-28, Volume: 1311, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Cells, Cultured; Culture Media, Conditioned; Endothelium; Enzyme Inhibitors; Glycoproteins; Imidazoles; Losartan; Myocardium; Protease Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Tetrazoles; Tissue Inhibitor of Metalloproteinases; Up-Regulation; Vasoconstrictor Agents

1996
Angiotensin II-induced progression of neointimal thickening in the balloon-injured rat carotid artery is AT1 receptor mediated.
    Arteriosclerosis, thrombosis, and vascular biology, 1996, Volume: 16, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Carotid Arteries; Carotid Artery Diseases; Catheterization; DNA; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles

1996
Angiotensin II receptor subtypes in the adrenals of pregnant rats.
    Molecular and cellular endocrinology, 1995, Oct-30, Volume: 114, Issue:1-2

    Topics: Adrenal Glands; Adrenal Medulla; Angiotensin II; Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Female; Humans; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Zona Glomerulosa

1995
Localization and quantitation of angiotensin AT1 and AT2 receptors in the pregnant and non-pregnant sheep uterus.
    Regulatory peptides, 1996, Mar-22, Volume: 61, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Anestrus; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Biphenyl Compounds; Fallopian Tubes; Female; Imidazoles; Losartan; Muscle, Smooth; Ovary; Pregnancy; Pregnancy, Animal; Pyridines; Radioligand Assay; Receptors, Angiotensin; Sheep; Tetrazoles; Uterus

1996
The angiotensin II subtype 2 (AT2) receptor is linked to protein kinase C but not cAMP-dependent pathways in the cardiomyocyte.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:2

    Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Biphenyl Compounds; Chick Embryo; Cyclic AMP; Enzyme Activation; Heart; Imidazoles; Isoproterenol; Losartan; Myocardium; Protein Kinase C; Pyridines; Receptors, Adrenergic, beta; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Vasoconstrictor Agents

1996
Subtypes of losartan-sensitive angiotensin receptor in the rabbit pulmonary artery.
    British journal of pharmacology, 1996, Volume: 117, Issue:7

    Topics: Angiotensin I; Animals; Antihypertensive Agents; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles

1996
Angiotensin II regulation of intracellular calcium in astroglia cultured from rat hypothalamus and brainstem.
    Journal of neurochemistry, 1996, Volume: 67, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Astrocytes; Biphenyl Compounds; Brain Stem; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gadolinium; Hypothalamus; Imidazoles; Indoles; Losartan; Nifedipine; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Ryanodine; Terpenes; Tetrazoles; Thapsigargin; Time Factors

1996
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure.
    The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles

1996
Angiotensin II type 2 receptor-mediated regulation of rat neuronal K+ channels.
    Circulation research, 1996, Volume: 79, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Imidazoles; Kinetics; Losartan; Neurons; Oligopeptides; Patch-Clamp Techniques; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1996
Differentiation of NG108-15 neuroblastoma cells by serum starvation or dimethyl sulfoxide results in marked differences in angiotensin II receptor subtype expression.
    Journal of neurochemistry, 1996, Volume: 66, Issue:3

    Topics: Binding, Competitive; Biphenyl Compounds; Blood; Cell Differentiation; Culture Media, Serum-Free; Dimethyl Sulfoxide; Imidazoles; Losartan; Neuroblastoma; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured

1996
Blockade of the renin-angiotensin system in heart failure in conscious dogs.
    Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Biphenyl Compounds; Captopril; Dogs; Heart Failure; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Pyridines; Reference Values; Renin-Angiotensin System; Tetrazoles

1995
Effects of intracerebroventricular injections of losartan or PD123319 on arterial pressure and heart rate of sodium replete and sodium deplete rats.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cohort Studies; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Sodium; Tetrazoles

1996
Effect of brain angiotensin II AT1, AT2, and cholinergic receptor antagonism on drinking in water-deprived rats.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Cholinergic Antagonists; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cholinergic; Receptors, Neurotransmitter; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Water Deprivation

1996
Blockade of central angiotensin II type 1 and type 2 receptors suppresses adrenalectomy-induced NaCl intake in rats.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Adrenalectomy; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drinking Behavior; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sodium Chloride; Tetrazoles

1996
Effects of DOCA pretreatment on neuronal sensitivity and cell responsiveness to angiotensin II, in the bed nucleus of the stria terminalis in the rat.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Desoxycorticosterone; Electrophysiology; Imidazoles; Iontophoresis; Losartan; Male; Pyridines; Rats; Rats, Wistar; Sensitivity and Specificity; Tetrazoles; Thalamic Nuclei

1996
The effect of losartan on drinking and NaCl intake in the rat in response to hyperosmotic and hypovolaemic stimuli: effect of route of administration and strain of rat.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Diuretics; Drinking; Drinking Behavior; Furosemide; Imidazoles; Injections, Intraventricular; Injections, Subcutaneous; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Saline Solution, Hypertonic; Shock; Sodium; Tetrazoles

1996
Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide.
    Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Enzyme Inhibitors; Hemodynamics; Hypertension; Imidazoles; Infusions, Intravenous; Kidney; Kinins; Losartan; Male; Meclofenamic Acid; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Tetrazoles

1995
Modulation by locally produced luminal angiotensin II of proximal tubular sodium reabsorption via an AT1 receptor.
    British journal of pharmacology, 1996, Volume: 119, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Kidney Tubules, Proximal; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium; Tetrazoles

1996
Angiotensin II receptor type 1 on granulosa and thecal cells of rabbit preovulatory follicles.
    Biochimica et biophysica acta, 1996, Oct-23, Volume: 1284, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cells, Cultured; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Granulosa Cells; Imidazoles; Kinetics; Losartan; Pyridines; Rabbits; Receptors, Angiotensin; Saralasin; Tetrazoles; Theca Cells; Up-Regulation

1996
Angiotensin II receptors involved in the enhancement of noradrenergic transmission in the caudal artery of the spontaneously hypertensive rat.
    British journal of pharmacology, 1996, Volume: 119, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Losartan; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1996
Multiple prejunctional actions of angiotensin II on noradrenergic transmission in the caudal artery of the rat.
    British journal of pharmacology, 1996, Volume: 119, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction

1996
Effects of non-peptide angiotensin II-receptor antagonists on pentylenetetrazol kindling in mice.
    Neuropeptides, 1996, Volume: 30, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anticonvulsants; Biphenyl Compounds; Convulsants; Drug Evaluation, Preclinical; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Tetrazoles

1996
The angiotensin AT2 receptor is present in the human fetal adrenal gland throughout the second trimester of gestation.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:11

    Topics: Adrenal Glands; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Female; Fetus; Gestational Age; Humans; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Tissue Distribution

1996
The effect of angiotensin II receptor antagonists on diethylstilbestrol-induced vascular changes in the rat anterior pituitary gland: a quantitative evaluation.
    Histology and histopathology, 1996, Volume: 11, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Diethylstilbestrol; Drug Implants; Imidazoles; Losartan; Male; Microcirculation; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Inbred F344; Silicone Elastomers; Tetrazoles

1996
Angiotensin II, via an action at AT1 receptors, may modulate the behavioural effects of ET-1 in conscious rats.
    Life sciences, 1996, Volume: 59, Issue:22

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Biphenyl Compounds; Drug Synergism; Endothelin-1; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1996
Losartan reduces phenylephrine constrictor response in aortic rings from spontaneously hypertensive rats. Role of nitric oxide and angiotensin II type 2 receptors.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1996
Lack of a beneficial effect of PD123319, an AT2-angiotensin receptor antagonist, on the course of ablation nephropathy in the rat.
    Kidney & blood pressure research, 1996, Volume: 19, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Chronic Disease; Imidazoles; Losartan; Male; Proteinuria; Pyridines; Rats; Rats, Wistar; Renal Insufficiency; Tetrazoles

1996
Angiotensin II receptors in the human adrenal gland.
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Adrenal Glands; Adult; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Gestational Age; Humans; Imidazoles; Losartan; Middle Aged; Pyridines; Receptors, Angiotensin; Tetrazoles; Tissue Distribution

1996
Opposite effects of angiotensin AT1 and AT2 receptor antagonists on recovery of mechanical function after ischemia-reperfusion in isolated working rat hearts.
    Circulation, 1996, Dec-15, Volume: 94, Issue:12

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cardiac Output; Coronary Circulation; Heart; Hemodynamics; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Ischemia; Myocardial Reperfusion; Oxygen Consumption; Pyridines; Rats; Rats, Sprague-Dawley; Systole; Tetrazoles; Ventricular Function, Left

1996
Presence of angiotensin II AT2 receptor binding sites in the adventitia of human kidney vasculature.
    Clinical and experimental pharmacology & physiology. Supplement, 1996, Volume: 3

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Carcinoma, Renal Cell; Humans; Imidazoles; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Losartan; Pyridines; Tetrazoles; Tunica Media

1996
Renal hemodynamics in rats with myocardial infarction: selective antagonism of angiotensin receptor subtypes.
    The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 2

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Pyridines; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Tetrazoles

1996
Angiotensin II-receptor stimulation of cytosolic calcium concentration in cultured renal resistance arterioles.
    The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 2

    Topics: Animals; Arterioles; Biphenyl Compounds; Calcium; Cells, Cultured; Cytosol; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Signal Transduction; Tetrazoles; Vascular Resistance

1996
The angiotensin type 2 receptor mediates RNA synthesis in A10 vascular smooth muscle cells.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Division; Cell Line; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA; Signal Transduction; Tetrazoles

1996
Angiotensin II stimulates the proliferation of osteoblast-rich populations of cells from rat calvariae.
    Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Humans; Imidazoles; Inositol 1,4,5-Trisphosphate; Kinetics; Losartan; Osteoblasts; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Skull; Tetrazoles

1997
Effect of angiotensin receptor blockade in the rabbit aorta: influence of the endothelium.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:12

    Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Enalapril; Endothelium, Vascular; Imidazoles; Losartan; Male; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles

1996
Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.
    The Journal of clinical investigation, 1997, Mar-01, Volume: 99, Issue:5

    Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cloning, Molecular; Culture Techniques; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enalaprilat; Gene Expression Regulation; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Artery; Renal Circulation; Ribonucleases; RNA, Messenger; Sodium, Dietary; Tetrazoles; Vasoconstrictor Agents

1997
ANG II modifies cardiomyocyte function via extracardiac and intracardiac neurons: in situ and in vitro studies.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cells, Cultured; Coculture Techniques; Coronary Circulation; Dogs; Female; Ganglia, Sympathetic; Guinea Pigs; Heart; Heart Ventricles; Imidazoles; Losartan; Male; Myocardial Contraction; Neurons; Pyridines; Stellate Ganglion; Tetrazoles; Timolol

1997
Angiotensin II activates distinct signal transduction pathways in astrocytes isolated from neonatal rat brain.
    Glia, 1997, Volume: 19, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Bradykinin; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Epoprostenol; Humans; Hypothalamus; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol Diacylglycerol-Lyase; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Type C Phospholipases

1997
Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity.
    Brain research. Molecular brain research, 1997, Volume: 45, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cloning, Molecular; COS Cells; Dithiothreitol; DNA, Complementary; Imidazoles; Locus Coeruleus; Losartan; Mice; Neuroblastoma; Oligopeptides; Olivary Nucleus; Polymerase Chain Reaction; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Tumor Cells, Cultured

1997
Angiotensin IV stimulates the proliferation of rat anterior pituitary cells in vitro.
    Biochemical and biophysical research communications, 1997, Mar-17, Volume: 232, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Division; Cells, Cultured; Imidazoles; Losartan; Male; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Wistar; Tetrazoles; Thymidine

1997
Angiotensin II induces apoptosis of adult ventricular myocytes in vitro.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:3

    Topics: Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Benzophenanthridines; Biphenyl Compounds; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Inhibitors; Imidazoles; Ionophores; Isoenzymes; Losartan; Myocardium; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1997
Angiotensin-responsive adrenal glomerulosa cell proteins: characterization by protease mapping, species comparison, and specific angiotensin receptor antagonists.
    Endocrinology, 1997, Volume: 138, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bucladesine; Cattle; Cells, Cultured; Chymotrypsin; Imidazoles; Losartan; Male; Methionine; Peptide Mapping; Protein Biosynthesis; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfur Radioisotopes; Tetrazoles; Zona Glomerulosa

1997
Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319.
    European journal of pharmacology, 1997, May-20, Volume: 326, Issue:2-3

    Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Drug Evaluation, Preclinical; Heart Rate; Imidazoles; Injections, Intravenous; Injections, Spinal; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazoles

1997
Paraventricular nucleus administration of DuP753 or PD123319 inhibits the effects of angiotensin on water and sodium intake.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1996, Volume: 29, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Drinking; Imidazoles; Losartan; Male; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Tetrazoles

1996
The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.
    The Journal of clinical investigation, 1997, Jul-15, Volume: 100, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Female; Imidazoles; Indazoles; Kidney; Losartan; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Sodium; Tetrazoles

1997
Regulation of thrombospondin-1 production by angiotensin II in rat heart endothelial cells.
    Biochimica et biophysica acta, 1997, Jun-27, Volume: 1357, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blotting, Northern; Cell Line; Cycloheximide; Dactinomycin; Endothelium; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Losartan; Membrane Glycoproteins; Myocardium; Protein Kinase C; Pyridines; Rats; Tetrazoles; Thrombospondins

1997
Role of endogenous angiotensin II on sympathetic reflexes in conscious rabbits.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypoxia; Imidazoles; Kidney; Losartan; Male; Nasopharynx; Pyridines; Rabbits; Reflex; Sympathetic Nervous System; Tetrazoles

1997
Central infusion of the AT1 receptor antagonist losartan inhibits thirst but not sodium appetite in cattle.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Behavior, Animal; Biphenyl Compounds; Brain; Cattle; Cerebrospinal Fluid; Dehydration; Drinking; Female; Hypertonic Solutions; Imidazoles; Injections, Intraventricular; Losartan; Pyridines; Sodium; Tetrazoles; Thirst; Water Deprivation

1997
Role of brain angiotensin II in thirst and sodium appetite of sheep.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Brain; Cerebral Ventricles; Dehydration; Diet, Sodium-Restricted; Diuresis; Female; Imidazoles; Infusions, Parenteral; Losartan; Mannitol; Naphthyridines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Saliva; Sheep; Sodium, Dietary; Tetrazoles; Thirst

1997
Bimodal effects of angiotensin II on migration of human and rat smooth muscle cells. Direct stimulation and indirect inhibition via transforming growth factor-beta 1.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Movement; Gene Expression; Humans; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta

1997
Angiotensin II-mediated growth and antigrowth effects in cultured neonatal rat cardiac myocytes and fibroblasts.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cells, Cultured; Endothelin-1; Fibroblasts; Growth Inhibitors; Growth Substances; Heart; Imidazoles; Inositol Phosphates; Losartan; Myocardium; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin

1997
Selective antagonism of the AT1 receptor inhibits angiotensin II stimulated DNA and protein synthesis in primary cultures of human proximal tubular cells.
    Kidney international, 1997, Volume: 52, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cells, Cultured; DNA; Humans; Imidazoles; Kidney Tubules, Proximal; Losartan; Protein Biosynthesis; Pyridines; Tetrazoles

1997
On the mechanism of the losartan-mediated inhibition of phosphatidylcholine biosynthesis in H9c2 cells.
    Biochimica et biophysica acta, 1997, Aug-16, Volume: 1347, Issue:2-3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Line; Cell Membrane; Choline; Cytosol; Imidazoles; Immunoblotting; Kinetics; Losartan; Phosphatidylcholines; Pyridines; Tetrazoles; Tritium

1997
Opposite feedback control of renin and aldosterone biosynthesis in the adrenal cortex by angiotensin II AT1-subtype receptors.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:3 Pt 2

    Topics: Adrenal Cortex; Aldosterone; Animals; Biphenyl Compounds; Feedback; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; RNA, Messenger; Tetrazoles

1997
Molecular mechanism of angiotensin II type I and type II receptors in cardiac hypertrophy of spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Cardiomegaly; Dose-Response Relationship, Drug; Down-Regulation; Enalapril; Imidazoles; Losartan; Male; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger

1997
Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
    Journal of hypertension, 1997, Volume: 15, Issue:10

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Electroencephalography; Hypertension; Imidazoles; Lisinopril; Losartan; Male; Neurons, Afferent; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thalamus; Vasoconstrictor Agents

1997
Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron.
    Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:11

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium Channels; Culture Techniques; Imidazoles; Losartan; Male; Nephrons; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger

1997
Angiotensin AT1 and AT2 receptor antagonism and myocardial ischemic injury.
    Circulation, 1997, Oct-21, Volume: 96, Issue:8

    Topics: Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Imidazoles; Losartan; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Up-Regulation

1997
Role of brain angiotensin in thirst and sodium appetite of rats.
    Peptides, 1997, Volume: 18, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Brain; Drinking; Eating; Furosemide; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thirst

1997
Effect of luminal angiotensin II on rabbit proximal convoluted tubule bicarbonate absorption.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Absorption; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bicarbonates; Biological Transport; Enalaprilat; Female; Imidazoles; Kidney Tubules, Proximal; Losartan; Pyridines; Rabbits

1997
Pharmacological profile of YM358, a novel nonpeptide angiotensin AT1 receptor antagonist.
    European journal of pharmacology, 1997, Sep-24, Volume: 335, Issue:2-3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Cattle; Decerebrate State; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1997
Influence of dietary sodium restriction on angiotensin II receptors in rat adrenals.
    Endocrinology, 1997, Volume: 138, Issue:12

    Topics: Adrenal Glands; Animals; Binding, Competitive; Blotting, Northern; Diet, Sodium-Restricted; Fluorescent Antibody Technique, Indirect; Imidazoles; In Vitro Techniques; Losartan; Male; Membranes; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tissue Distribution

1997
Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit.
    Brain research, 1997, Oct-24, Volume: 772, Issue:1-2

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Denervation; Female; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Pressoreceptors; Pyridines; Rabbits; Receptors, Angiotensin; Sympathetic Nervous System

1997
Effect of PD 123319, an AT-2 antagonist, on renal function of the anesthetized dog: comparison with EXP 3174, an AT-1 blocker.
    Kidney & blood pressure research, 1997, Volume: 20, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Diuresis; Dogs; Drug Combinations; Glomerular Filtration Rate; Imidazoles; Injections, Intra-Arterial; Kidney; Losartan; Male; Natriuresis; Pyridines; Renal Circulation; Tetrazoles

1997
The effects of angiotensin II and specific angiotensin receptor blockers on embryonic cardiac development and looping patterns.
    Developmental biology, 1997, Dec-15, Volume: 192, Issue:2

    Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Fetal Heart; Fibroblasts; Heart Ventricles; Hypertrophy; Imidazoles; Losartan; Morphogenesis; Myocardium; Myosin Heavy Chains; Organ Culture Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1997
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values

1998
AT1 and AT2 receptor blockade and epinephrine release during insulin-induced hypoglycemia.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Enalapril; Epinephrine; Heart Rate; Humans; Hypoglycemia; Imidazoles; Insulin; Kinetics; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

1998
Effects of AT1 and AT2 angiotensin receptor antagonists in angiotensin II-infused rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Body Weight; Coronary Vessels; Femoral Artery; Heart; Imidazoles; Infusions, Parenteral; Kidney; Losartan; Organ Size; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1998
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hindlimb; Imidazoles; Losartan; Male; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1998
Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Immunoglobulin G; Lisinopril; Losartan; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Vasodilation

1998
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote

1998
Local upregulation of colonic angiotensin II receptors enhances potassium excretion in chronic renal failure.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Colon; Imidazoles; Kidney Failure, Chronic; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Rubidium Radioisotopes; Up-Regulation

1998
Effects of angiotensin II on bone cells in vitro.
    Journal of cellular physiology, 1998, Volume: 175, Issue:1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Binding, Competitive; Cell Division; Cells, Cultured; Collagen; DNA; Femur Head; Fetus; Humans; Imidazoles; Losartan; Osteoblasts; Osteoclasts; Parathyroid Hormone; Pyridines; Rats; Skull; Vasoconstrictor Agents

1998
Comparison of angiotensin II type-1 and type-2 receptor antagonists on angiotensin II-induced IP3 generation in cardiomyocytes.
    General pharmacology, 1998, Volume: 30, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Chick Embryo; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Losartan; Myocardium; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

1998
Role of AT1 and AT2 receptors in the plasma clearance of angiotensin II.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Half-Life; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin

1998
Acute sodium depletion modifies septo-preoptic neuron sensitivities to neurohormones.
    Brain research, 1998, Mar-16, Volume: 787, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensins; Animals; Imidazoles; Losartan; Male; Neurons; Preoptic Area; Pyridines; Rats; Rats, Wistar; Septum Pellucidum; Sodium

1998
Role of AT2 receptors in the cardiovascular events following microinjection of angiotensin II into the superior colliculus of anaesthetised rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:2

    Topics: Anesthesia, General; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Microinjections; Microspheres; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Regional Blood Flow; Superior Colliculi

1998
Documentation of angiotensin II receptors in glomerular epithelial cells.
    The American journal of physiology, 1998, Volume: 274, Issue:3 Pt 2

    Topics: Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Blotting, Western; Cells, Cultured; Cyclic AMP; Epithelial Cells; Imidazoles; Kidney Glomerulus; Losartan; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction

1998
Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells.
    Biochimica et biophysica acta, 1998, Feb-04, Volume: 1401, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Cattle; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Immunoblotting; Losartan; Lymphokines; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Transcription Factors; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents

1998
Distribution and functional significance of angiotensin-II AT1- and AT2-receptor subtypes in the rat adrenal gland.
    Endocrine research, 1998, Volume: 24, Issue:1

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1998
The AT2 receptor-mediated stimulation of adrenal catecholamine release may potentiate the AT1 receptor-mediated aldosterone secretagogue action of angiotensin-II in rats.
    Endocrine research, 1998, Volume: 24, Issue:1

    Topics: Adrenal Glands; Aldosterone; Alprenolol; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Catecholamines; Cells, Cultured; Chromaffin Cells; Culture Techniques; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Zona Glomerulosa

1998
Relationship between the increase in Ca2+ transient and contractile force induced by angiotensin II in aequorin-loaded rabbit ventricular myocardium.
    Cardiovascular research, 1998, Volume: 37, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aequorin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bupranolol; Calcium; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Microinjections; Myocardial Contraction; Myocardium; Prazosin; Pyridines; Rabbits; Stimulation, Chemical

1998
Effects of angiotensin II on endothelial cell growth: role of AT-1 and AT-2 receptors.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Cattle; Cell Count; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Receptors, Angiotensin

1998
The receptor subtype mediating the action of angiotensin II on intracellular sodium in rat proximal tubules.
    British journal of pharmacology, 1998, Volume: 124, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Extracellular Space; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium

1998
Growth response of human coronary smooth muscle cells to angiotensin II and influence of angiotensin AT1 receptor blockade.
    Coronary artery disease, 1998, Volume: 9, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Calcium; Cell Division; Cells, Cultured; Coronary Vessels; DNA; Humans; Imidazoles; Immunohistochemistry; Losartan; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Protein Biosynthesis; Pyridines; Receptors, Angiotensin; Vasoconstrictor Agents

1998
Characterization and distribution of angiotensin II receptor subtypes in the mouse brain.
    European journal of pharmacology, 1998, May-01, Volume: 348, Issue:1

    Topics: Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Caudate Nucleus; Imidazoles; In Vitro Techniques; Kinetics; Ligands; Locus Coeruleus; Losartan; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin

1998
Angiotensin AT1 receptor-mediated excitation of rat carotid body chemoreceptor afferent activity.
    The Journal of physiology, 1998, Aug-01, Volume: 510 ( Pt 3)

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Carotid Body; Electric Stimulation; Electrophysiology; Imidazoles; Iodine Radioisotopes; Ligands; Losartan; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1998
Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Angiotensin II; Animals; Binding, Competitive; Hypertension; Hypothalamus; Imidazoles; Kinetics; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Species Specificity

1998
Characterization of angiotensin II receptors (binding and mRNA) in the rat thyroid gland.
    Journal of molecular endocrinology, 1998, Volume: 20, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; DNA Primers; Imidazoles; Kinetics; Losartan; Male; Polymerase Chain Reaction; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Thyroid Gland

1998
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water

1998
Angiotensin II induces acrosomal exocytosis in bovine spermatozoa.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Acrosin; Acrosome; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Calcimycin; Cattle; Exocytosis; Female; Humans; Imidazoles; Losartan; Male; Pyridines; Receptors, Angiotensin; Sperm Capacitation; Sperm-Ovum Interactions

1998
Differential action of angiotensin II and activity of angiotensin-converting enzyme in human bypass grafts.
    The Journal of thoracic and cardiovascular surgery, 1998, Volume: 116, Issue:2

    Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Middle Aged; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saphenous Vein; Thoracic Arteries; Vasoconstriction; Vasoconstrictor Agents

1998
Losartan antagonism of angiotensin-II-induced potassium secretion across rat colon.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Colon; Dose-Response Relationship, Drug; Drug Antagonism; Extracellular Space; Hydrolysis; Imidazoles; In Vitro Techniques; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tetrazoles

1998
Angiotensin receptor blockade blunts hyperinsulinemia-induced hypertension in rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:2

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Hyperinsulinism; Hypertension; Imidazoles; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin

1998
Microvasculature in angiotensin II-dependent cardiac hypertrophy in the rat.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterioles; Capillaries; Hypertension; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Vasoconstrictor Agents

1998
Different receptors for angiotensin II at pre- and postjunctional level of the canine mesenteric and pulmonary arteries.
    British journal of pharmacology, 1998, Volume: 124, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dogs; Female; Imidazoles; Losartan; Male; Mesenteric Arteries; Neuroeffector Junction; Pulmonary Artery; Pyridines; Receptors, Angiotensin; Saralasin

1998
Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Collagen; Enalapril; Gene Expression; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger

1998
Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle.
    Circulation research, 1998, Oct-19, Volume: 83, Issue:8

    Topics: Actins; Angiotensin II; Animals; Anti-Arrhythmia Agents; Aorta; Calcium; Cell Adhesion Molecules; Cells, Cultured; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Insulin; Receptors, Angiotensin; src-Family Kinases; Tyrosine

1998
Angiotensin II potentiates DNA synthesis in AT-1 transformed cardiomyocytes.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:10

    Topics: Angiotensin II; Animals; Antigens, Polyomavirus Transforming; Cell Cycle; Cell Division; Cell Line, Transformed; Cyclin B; Cyclin B1; Cyclins; DNA Replication; Gene Expression Regulation; Imidazoles; Losartan; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Myocardium; Phosphorylation; Protamine Kinase; Pyridines; Simian virus 40; Thymidine; Tumor Cells, Cultured

1998
Modulation of the vascular smooth muscle angiotensin subtype 2 (AT2) receptor by angiotensin II.
    Biochemical and biophysical research communications, 1998, Nov-18, Volume: 252, Issue:2

    Topics: Angiotensin II; Animals; Antibody Specificity; Cells, Cultured; COS Cells; DNA, Complementary; Glycosylation; Imidazoles; Losartan; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Transfection

1998
Effects of losartan and PD123319 on antigensin II-induced proto-oncogene expression and protein synthesis in cultured neonatal rat cardiac myocytes.
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1997, Volume: 22, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Gene Expression; Imidazoles; Losartan; Myocardium; Proto-Oncogene Proteins c-myc; Pyridines; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger

1997
Guinea pig airway hyperresponsiveness induced by blockade of the angiotensin II type 1 receptor. Role for endogenous nitric oxide.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:1

    Topics: Acetylcholine; Airway Obstruction; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Guinea Pigs; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines

1999
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors.
    British journal of pharmacology, 1998, Volume: 125, Issue:7

    Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction

1998
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:1

    Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Culture Media; DNA; Female; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; Losartan; Mice; Mice, Knockout; Muscle Development; Muscle, Smooth, Vascular; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Binding; Pyridines; Receptors, Angiotensin; Vanadates

1999
Role of the angiotensin II AT2-subtype receptors in the blood pressure-lowering effect of losartan in salt-restricted rats.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restricted; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System

1998
AT1 receptors mediate angiotensin II uptake and transport by bovine brain microvessel endothelial cells in primary culture.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Cattle; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1999
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Blood Pressure; Heart Rate; Hemodynamics; Homozygote; Hypertension; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Renin

1999
Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction

1999
The role of angiotensin II and of its receptor subtypes in the acetic acid-induced abdominal constriction test.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:2

    Topics: Acetic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Colic; Imidazoles; Losartan; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Pyridines; Receptors, Angiotensin; Saralasin

1999
Ca2+ mobilization in adult rat cardiomyocytes by angiotensin type 1 and 2 receptors.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Cells, Cultured; Heart; Imidazoles; Kinetics; Losartan; Male; Myocardial Contraction; Myocardium; Potassium Chloride; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors

1998
A signaling pathway for stimulation of Na+ uptake induced by angiotensin II in primary cultured rabbit renal proximal tubule cells.
    The Journal of veterinary medical science, 1999, Volume: 61, Issue:2

    Topics: Amiloride; Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Cyclic AMP; Diuretics; Imidazoles; Kidney Tubules, Proximal; Losartan; Male; Protein Kinase C; Pyridines; Rabbits; Receptors, Angiotensin; Signal Transduction; Sodium; Staurosporine; Tetradecanoylphorbol Acetate

1999
Different pathways for Ca2+ mobilization by angiotensin II and carbachol in the circular muscle of the guinea-pig ileum.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Isradipine; Losartan; Male; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nickel; Nifedipine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Vasoconstrictor Agents; Verapamil

1999
Analysis of responses to angiotensin I (3-10) and Leu3 angiotensin (3-8) in the pulmonary vascular bed of the cat.
    American journal of therapeutics, 1998, Volume: 5, Issue:5

    Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Male; Peptide Fragments; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1998
Angiotensin II exacerbates lipopolysaccharide-induced contractile depression in rabbit cardiac myocytes.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cells, Cultured; Chelating Agents; Cyclic GMP; Enzyme Inhibitors; Female; Heart Ventricles; Imidazoles; Indoles; Lipopolysaccharides; Losartan; Male; Mitochondria; Muscle Fibers, Skeletal; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rabbits; Receptors, Angiotensin; Sepsis; Ventricular Function

1999
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:5

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclic GMP; Hypertension, Renovascular; Imidazoles; Kidney; Losartan; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation

1999
Effect of luminal angiotensin II receptor antagonists on proximal tubule transport.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium

1999
Vascular angiotensin II receptor and calcium signaling in toadfish.
    General and comparative endocrinology, 1999, Volume: 115, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blood Vessels; Calcium; Calcium Signaling; Cell Membrane; Female; Fishes; Imidazoles; Losartan; Male; Potassium; Pyridines; Receptors, Angiotensin

1999
Renal cellular response to ureteral obstruction: role of maturation and angiotensin II.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Imidazoles; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

1999
Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro.
    Circulation research, 1999, Jul-23, Volume: 85, Issue:2

    Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Antisense Elements (Genetics); Blotting, Southern; Cells, Cultured; Fibroblasts; Gene Expression; Heart Ventricles; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Losartan; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical

1999
Angiotensin II stimulates DNA and protein synthesis in vascular smooth muscle cells from human arteries: role of extracellular signal-regulated kinases.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arteries; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; DNA Replication; Humans; Imidazoles; Losartan; Muscle, Smooth, Vascular; Protein Biosynthesis; Pyridines; Receptors, Angiotensin; Signal Transduction; Vasoconstrictor Agents

1999
Modulation of vascular development and injury by angiotensin II.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Carotid Arteries; Catheterization; DNA; Embryonic and Fetal Development; Female; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

1999
Aminopeptidase A activity and angiotensin III effects on [Ca2+]i along the rat nephron.
    Kidney international, 1999, Volume: 56, Issue:3

    Topics: Aminopeptidases; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Calcium; Glutamyl Aminopeptidase; Imidazoles; Immunohistochemistry; In Vitro Techniques; Intracellular Fluid; Losartan; Male; Nephrons; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin

1999
In vivo study of AT(1) and AT(2) angiotensin receptors in apoptosis in rat blood vessels.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Apoptosis; Blood Pressure; Body Weight; Drug Interactions; Imidazoles; Losartan; Male; Muscle Development; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents

1999
Activation of AT(2) receptors by endogenous angiotensin II is involved in flow-induced dilation in rat resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 1

    Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Blotting, Western; Imidazoles; Losartan; Mesenteric Arteries; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Saralasin; Stress, Mechanical; Vascular Resistance; Vasodilation

1999
Functional evidence for an angiotensin IV receptor in rat resistance arteries.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Drug Interactions; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Serotonin; Tachyphylaxis; Tetrazoles; Vascular Resistance

1999
Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum.
    The Journal of biological chemistry, 1999, Oct-29, Volume: 274, Issue:44

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Differentiation; Cell Movement; Cerebellum; Culture Techniques; Fluorescent Antibody Technique, Indirect; Imidazoles; Losartan; Microtubule-Associated Proteins; Neurites; Oligopeptides; Pyridines; Rats; Rats, Long-Evans; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; tau Proteins; Tubulin

1999
Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model.
    Cardiovascular research, 1999, Volume: 42, Issue:3

    Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cell Division; Coronary Disease; Coronary Vessels; Culture Techniques; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Recurrence; Swine; Tetrazoles

1999
Angiotensin-(1-7) binds at the type 1 angiotensin II receptors in rat renal cortex.
    Regulatory peptides, 1999, Oct-22, Volume: 84, Issue:1-3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Iodine Radioisotopes; Kidney Cortex; Losartan; Male; Peptide Fragments; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin

1999
Angiotensin II receptor blockade during gestation attenuates collagen formation in the developing rat heart.
    Cardiovascular research, 1999, Volume: 43, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Birth Weight; Blotting, Western; Collagen; Female; Heart; Imidazoles; In Situ Hybridization; Losartan; Organ Size; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta

1999
Participation of angiotensin receptors in acute hypoxia in mice. II. Effects of angiotensin II nonpeptide receptor ligands losartan (DuP-753) and PD-123319.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:7

    Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hypoxia, Brain; Imidazoles; Injections, Intraventricular; Ligands; Losartan; Male; Mice; Mice, Inbred ICR; Pyridines; Receptors, Angiotensin; Seizures; Vasoconstrictor Agents

1999
Losartan reduces the vasorelaxant effect of atrial natriuretic peptide on basal tone in aorta.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1999, Volume: 21, Issue:8

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Atrial Natriuretic Factor; Calcium; Female; Imidazoles; In Vitro Techniques; Intracellular Fluid; Isotonic Solutions; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance; Vasodilation

1999
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin; Vasoconstriction

1999
The effects of angiotensin metabolites on the regulation of coagulation and fibrinolysis in cultured rat aortic endothelial cells.
    Thrombosis and haemostasis, 1999, Volume: 82, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Coagulation; Endothelium, Vascular; Fibrinolysis; Gene Expression Regulation; Imidazoles; Lipoproteins; Losartan; Plasminogen Activator Inhibitor 1; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thromboplastin; Tissue Plasminogen Activator

1999
Angiotensin II and retinal pericytes migration.
    Biochemical and biophysical research communications, 1999, Dec-20, Volume: 266, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cattle; Cell Movement; Chemotaxis; Imidazoles; Losartan; Neovascularization, Physiologic; Pericytes; Pyridines; Retina

1999
Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases.
    Cardiovascular research, 1999, Volume: 44, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Lisinopril; Losartan; NADH Dehydrogenase; NADPH Oxidases; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Superoxides

1999
Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-18, Volume: 97, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Binding, Competitive; Blotting, Northern; Cardiomegaly; Gene Expression Regulation; Heart Atria; Heart Ventricles; Humans; Imidazoles; Immunohistochemistry; Losartan; Mice; Mice, Transgenic; Myocardium; Phenotype; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tissue Distribution; Transgenes; Ventricular Remodeling

2000
Angiotensin III depressor action in the conscious rabbit is blocked by losartan but not PD 123319.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 1

    Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Imidazoles; Losartan; Male; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

2000
Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Actinin; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antigens, CD; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Heart Ventricles; Hydralazine; Imidazoles; Integrin alphaV; Integrin beta Chains; Integrin beta1; Integrin beta3; Integrins; Irbesartan; Laminin; Losartan; Myocardium; Phosphorylation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Up-Regulation; Vitronectin

2000
Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Gene Expression Regulation, Developmental; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Iodine Radioisotopes; Ligands; Losartan; Male; Muscle, Smooth, Vascular; Oligopeptides; Oxygen; Pulmonary Alveoli; Pulmonary Artery; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents

2000
Modulation of the AT2 subtype receptor gene activation and expression by the AT1 receptor in endothelial cells.
    Journal of hypertension, 1999, Volume: 17, Issue:12 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Endothelium, Vascular; Gene Expression; Gene Expression Regulation; Imidazoles; Losartan; Promoter Regions, Genetic; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcriptional Activation

1999
Brain AT(2) receptor mediate vasodepressor response to footshocks: role of kinins and nitric oxide.
    Brain research bulletin, 2000, Mar-01, Volume: 51, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Brain; Electroshock; Enzyme Inhibitors; Extremities; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin

2000
Angiotensin stimulates TGF-beta1 and clusterin in the hydronephrotic neonatal rat kidney.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Clusterin; Glycoproteins; Imidazoles; Kidney; Losartan; Molecular Chaperones; Pyridines; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ureteral Obstruction; Vasoconstrictor Agents

2000
Role of angiotensin II AT1 and AT2 subtype receptors in the regulation of atrial natriuretic peptide expression in salt-restricted rats.
    Basic research in cardiology, 2000, Volume: 95, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Imidazoles; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Chloride

2000
Angiotensin AT(2) receptors mediate vasodepressor response to footshock in rats. Role of kinins, nitric oxide and prostaglandins.
    European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1

    Topics: Animals; Blood Pressure; Bradykinin; Electroshock; Heart Rate; Imidazoles; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

2000
Tissue angiotensin II and endothelin-1 modulate differently the response to flow in mesenteric resistance arteries of normotensive and spontaneously hypertensive rats.
    British journal of pharmacology, 2000, Volume: 130, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Viscosity; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; Losartan; Mesenteric Arteries; Muscle Tonus; Perindopril; Phenylpropionates; Pyridines; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Splanchnic Circulation; Vascular Resistance; Vasodilation

2000
Angiotensin II induces contraction and proliferation of human hepatic stellate cells.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Division; Cell Size; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Humans; Imidazoles; Indomethacin; Iodine Radioisotopes; Liver; Losartan; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Penicillamine; Pyridines; Radioligand Assay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Nitrite; Thymidine; Vasoconstrictor Agents

2000
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan

2000
Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding.
    Biochimica et biophysica acta, 2000, Jun-02, Volume: 1497, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Alanine; Amino Acid Sequence; Amino Acid Substitution; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cloning, Molecular; COS Cells; DNA, Complementary; DNA, Recombinant; Ferrets; Imidazoles; Iodine Radioisotopes; Losartan; Molecular Sequence Data; Plasmids; Protein Binding; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Threonine

2000
Role of bradykinins and nitric oxide in the AT2 receptor-mediated hypotension.
    Journal of human hypertension, 2000, Volume: 14 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Drug Administration Routes; Enzyme Inhibitors; Hot Temperature; Hypertension; Hypotension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Shock; Vasodilation

2000
Renin angiotensin system of rabbit clitoral cavernosum: interaction with nitric oxide.
    The Journal of urology, 2000, Volume: 164, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Clitoris; Culture Techniques; Female; Imidazoles; Losartan; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Pyridines; Rabbits; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2000
Angiotensin II releases 20-HETE from rat renal microvessels.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Arterioles; Capillaries; Cytochrome P-450 Enzyme System; Estrenes; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Imidazoles; Kidney; Losartan; Male; NADP; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Type C Phospholipases

2000
Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation.
    Circulation, 2000, Oct-24, Volume: 102, Issue:17

    Topics: Angiotensin II; Animals; Cell Communication; Cromolyn Sodium; Endothelium; Flow Cytometry; Imidazoles; Leukocytes; Losartan; P-Selectin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Up-Regulation

2000
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
    Regulatory peptides, 2000, Nov-24, Volume: 95, Issue:1-3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine

2000
AT-1 receptor and phospholipase C are involved in angiotensin III modulation of hypothalamic noradrenergic transmission.
    Cellular and molecular neurobiology, 2000, Volume: 20, Issue:6

    Topics: Angiotensin III; Angiotensin Receptor Antagonists; Animals; Enzyme Inhibitors; Hypothalamus; Imidazoles; In Vitro Techniques; Inositol Phosphates; Losartan; Male; Neurons; Norepinephrine; Potassium Chloride; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Synaptic Transmission; Type C Phospholipases; Tyrosine 3-Monooxygenase

2000
Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice.
    American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:1

    Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Crosses, Genetic; Feedback; Genotype; Imidazoles; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Losartan; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Organ Specificity; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription, Genetic

2001
Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Cell Count; Dextrans; Endothelium; Fluoresceins; Humans; Hyperoxia; Hypoxia; Imidazoles; Infant, Newborn; Losartan; Mice; Mice, Inbred C57BL; Perindopril; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retinal Ganglion Cells; Retinal Neovascularization; Retinopathy of Prematurity

2001
Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis in the rat.
    Synapse (New York, N.Y.), 2001, Volume: 40, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Drug Interactions; Functional Laterality; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Neurons; Pressoreceptors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reticular Formation; Time Factors

2001
Functional expression of angiotensin II receptors in type-I cells of the rat carotid body.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 441, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Carotid Body; Gene Expression; Imidazoles; Immunohistochemistry; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Fluorescence

2001
Angiotensin II-induced depolarizations in hamster submandibular ganglion neurons.
    The Bulletin of Tokyo Dental College, 2000, Volume: 41, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Barium; Cricetinae; Electric Impedance; Ganglia, Parasympathetic; Imidazoles; Losartan; Male; Membrane Potentials; Neurons; Neurotransmitter Agents; Potassium Channels; Pyridines; Receptors, Angiotensin; Sodium Channels; Submandibular Gland

2000
Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2

    Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Imidazoles; In Vitro Techniques; Losartan; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Patch-Clamp Techniques; Peptides; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetraethylammonium; Vasodilation

2001
Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons.
    Regulatory peptides, 2001, Apr-20, Volume: 98, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Columbidae; Drinking Behavior; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Serotonin

2001
Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:4

    Topics: Analysis of Variance; Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Imidazoles; Losartan; Male; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptide Fragments; Prostheses and Implants; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2001
Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Brain; Cerebral Ventricles; Epinephrine; Heart Rate; Hemodynamics; Homeostasis; Hypoglycemia; Imidazoles; Injections, Intraventricular; Insulin; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reflex

2001
Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Androstadienes; Angiotensin II; Animals; Cell Count; Cell Division; Dose-Response Relationship, Drug; Imidazoles; Liposomes; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Pyridines; Thymidine; Wortmannin

2001
Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure Determination; Consciousness; Iloprost; Imidazoles; In Vitro Techniques; Losartan; Male; Microcirculation; Muscle, Skeletal; Muscle, Smooth, Vascular; Oxygen; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sodium, Dietary; Vascular Resistance; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2001
Angiotensin receptor in the heart of Bothrops jararaca snake.
    European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Amide; Angiotensin II; Animals; Binding, Competitive; Bothrops; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Imidazoles; Inositol Phosphates; Losartan; Male; Membranes; Myocardium; Pyridines; Receptors, Angiotensin; Saralasin; Tritium

2001
Effects of angiotensin-converting enzyme and angiotensin II on hypoxia-induced proliferation of cultured intra-pulmonary artery smooth muscle cells.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Division; Cell Hypoxia; Cells, Cultured; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Rabbits

2000
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.
    The American journal of pathology, 2001, Volume: 158, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Imidazoles; Infusion Pumps; Kidney; Losartan; NF-kappa B; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Transcription Factor AP-1

2001
At receptor inhibition affects the noradrenaline sensitivity in isolated portal vein of normotensive rat.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2001, Volume: 23, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Drug Resistance; Drug Synergism; Imidazoles; In Vitro Techniques; Losartan; Male; Norepinephrine; Portal Vein; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Splanchnic Circulation; Vasoconstriction

2001
Regulation of K+ transport in the rat distal colon via angiotensin II subtype receptors and K+ -pathways.
    Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport, Active; Carrier Proteins; Colon; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Potassium; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase

2001
Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning.
    Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brain; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Imidazoles; Injections, Intraventricular; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium, Dietary

2001
Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Kidney Tubules, Proximal; Losartan; Nephrons; Nitrendipine; Parathyroid Hormone; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Second Messenger Systems; Sodium; Thionucleotides; Vasoconstrictor Agents

2001
Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons.
    Journal of neurophysiology, 2001, Volume: 85, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arachidonic Acids; Brain; Cytarabine; Enzyme Inhibitors; Imidazoles; Lipoxygenase; Lipoxygenase Inhibitors; Losartan; Nerve Tissue Proteins; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Synaptic Transmission; Tetrodotoxin; Time Factors

2001
Angiotensin II activates nuclear transcription factor-kappaB in aorta of normal rats and in vascular smooth muscle cells of AT1 knockout mice.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16 Suppl 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Binding Sites; Cells, Cultured; Consensus Sequence; Endothelium, Vascular; Gene Expression Regulation; Imidazoles; Losartan; Mice; Mice, Knockout; Models, Biological; Muscle, Smooth, Vascular; NF-kappa B; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transcription Factors

2001
Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction.
    Cardiovascular research, 2001, Volume: 51, Issue:1

    Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Therapy, Combination; Female; Imidazoles; Losartan; Models, Animal; Myocardial Infarction; Myocardium; Pyridines; Radioligand Assay; Ramipril; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regression Analysis; Sheep; Ventricular Remodeling

2001
Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells.
    European journal of pharmacology, 2001, May-18, Volume: 420, Issue:1

    Topics: Angiotensin II; Animals; Calcium; Cell Line; Cell Membrane Permeability; Dose-Response Relationship, Drug; Imidazoles; Inositol 1,4,5-Trisphosphate; Liposomes; Losartan; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Potassium Chloride; Pyridines

2001
Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; COS Cells; DNA, Complementary; Imidazoles; Inosine Triphosphate; Losartan; Mutagenesis; Oligopeptides; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; Thermodynamics; Transfection

2001
Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Calcium; Cell Division; Cell Line; DNA; Epidermal Growth Factor; Imidazoles; Immunoblotting; Kidney Tubules, Proximal; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Pyridines; Radioligand Assay; Receptors, Angiotensin; Transfection; Vanadates

2001
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
    Journal of neurochemistry, 2001, Volume: 78, Issue:3

    Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase

2001
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation

2001
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
    The Journal of endocrinology, 2001, Volume: 171, Issue:1

    Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission

2001
Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice.
    Regulatory peptides, 2001, Oct-15, Volume: 102, Issue:1

    Topics: Adrenal Medulla; Angiotensin II; Animals; Autoradiography; Blood Pressure; Female; Gene Expression Regulation; Genotype; Imidazoles; In Situ Hybridization; Losartan; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, Mutant Strains; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription, Genetic; Vasoconstrictor Agents; Zona Glomerulosa

2001
Identification and characterization of functional angiotensin II type 1 receptors on immortalized human fetal aortic vascular smooth muscle cells.
    Molecular and cellular endocrinology, 2001, Oct-25, Volume: 183, Issue:1-2

    Topics: Angiotensins; Animals; Antihypertensive Agents; Aorta; Calcium; Cell Line; Cell Membrane; Culture Media, Serum-Free; Fetus; Genes, Reporter; Humans; Imidazoles; Losartan; Luciferases; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction

2001
Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Drug Synergism; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Severity of Illness Index

2001
Corpuscles of Stannius secrete renin or an isorenin that regulates cardiovascular function in freshwater North American eels, Anguilla rostrata LeSueur.
    General and comparative endocrinology, 2001, Volume: 124, Issue:2

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Anguilla; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Captopril; Endocrine Glands; Female; Imidazoles; Losartan; Pepstatins; Protease Inhibitors; Pyridines; Renin; Renin-Angiotensin System; Ultrasonography, Doppler

2001
Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Female; Imidazoles; Losartan; Postpartum Period; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction; Vasoconstrictor Agents

2001
Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:12

    Topics: Aggrecans; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; DNA, Complementary; Extracellular Matrix Proteins; Glycoproteins; Heparan Sulfate Proteoglycans; Imidazoles; Lectins, C-Type; Losartan; Male; Muscle, Smooth, Vascular; Proteoglycans; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger

2001
Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.
    Regulatory peptides, 2002, Jan-15, Volume: 103, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cell Membrane; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Tubules, Proximal; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saralasin; Sodium-Potassium-Exchanging ATPase; Swine

2002
Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Chloride, Dietary; Water-Electrolyte Balance

2002
Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats.
    The Journal of physiology, 2002, Jan-01, Volume: 538, Issue:Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Imidazoles; Kidney Cortex; Kidney Medulla; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Saralasin; Vasoconstrictor Agents

2002
Intracellular angiotensin II inhibits heterologous receptor stimulated Ca2+ entry.
    Life sciences, 2001, Nov-30, Volume: 70, Issue:2

    Topics: Angiotensin II; Animals; Calcium; Cell Line; Imidazoles; Liposomes; Losartan; Muscle, Smooth; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serotonin; Uridine Triphosphate

2001
Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Angiotensin II; Animals; Antibodies; Anticoagulants; Antihypertensive Agents; Becaplermin; Cattle; Cells, Cultured; Chemotaxis; Dipeptides; Endothelial Growth Factors; Imidazoles; Losartan; Lymphokines; Matrix Metalloproteinase 2; Microcirculation; Neovascularization, Physiologic; Pericytes; Platelet-Derived Growth Factor; Protease Inhibitors; Proto-Oncogene Proteins c-sis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retina; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents

2002
The mechanism of angiotensin II binding downregulation by high glucose in primary renal proximal tubule cells.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Glucose; Imidazoles; Iodine Radioisotopes; Kidney Tubules, Proximal; Lipid Peroxidation; Losartan; Nifedipine; Oxidants; Oxidative Stress; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rabbits; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Vasoconstrictor Agents

2002
AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.
    Behavioural brain research, 2002, Apr-01, Volume: 131, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Avoidance Learning; Cognition; Conditioning, Operant; Exploratory Behavior; Imidazoles; Injections, Intraventricular; Losartan; Male; Mental Recall; Motor Activity; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2002
Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:4

    Topics: Adenocarcinoma; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Apoptosis; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Imidazoles; Losartan; Lung Neoplasms; Pulmonary Alveoli; Pulmonary Fibrosis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Respiratory Mucosa; Tetrazoles; Tumor Cells, Cultured; Vasoconstrictor Agents

2002
The involvement of AT(2)-receptor in the antithrombotic effect of losartan in renal hypertensive rats.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Fibrinolytic Agents; Hypertension, Renovascular; Imidazoles; Ligation; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Venae Cavae; Venous Thrombosis

2000
125I[Sar(1)Ile(8)] angiotensin II has a different affinity for AT(1) and AT(2) receptor subtypes in ovine tissues.
    Regulatory peptides, 2002, May-15, Volume: 105, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Angiotensins; Animals; Aorta; Female; Heart; Imidazoles; Iodine Radioisotopes; Isotope Labeling; Losartan; Myocardium; Pregnancy; Pregnancy, Animal; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sheep; Uterus

2002
Influence of estrogen and/or progesterone on isolated ovariectomized rat uterus. Responsiveness to Ang II.
    Pharmacology, 2002, Volume: 64, Issue:4

    Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Estrogens; Female; Imidazoles; In Vitro Techniques; Losartan; Muscle Contraction; Ovariectomy; Progesterone; Pyridines; Rats; Rats, Wistar; Uterus

2002
The effect of angiotensin II on mitogen-activated protein kinase in human cardiomyocytes.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:4

    Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Culture Techniques; Drug Synergism; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Losartan; Middle Aged; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2000
Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.
    Brain research. Molecular brain research, 2002, Mar-28, Volume: 99, Issue:2

    Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypoxia-Ischemia, Brain; Imidazoles; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Losartan; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, N-Methyl-D-Aspartate; Sodium Azide; Trypan Blue; Vasodilator Agents

2002
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
    Life sciences, 2002, Mar-22, Volume: 70, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins

2002
Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP.
    Journal of hypertension, 2002, Volume: 20, Issue:6

    Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Female; Imidazoles; Injections, Intravenous; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan

2002
Angiotensin actions on the isolated rat uterus during the estrous cycle: influence of resting membrane potential and uterine morphology.
    Pharmacology, 2002, Volume: 65, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Estrous Cycle; Female; Imidazoles; In Vitro Techniques; Losartan; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Uterus; Vasoconstrictor Agents

2002
Angiotensin II induces apoptosis in rat glomerular epithelial cells.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Antihypertensive Agents; bcl-2-Associated X Protein; Cells, Cultured; DNA Fragmentation; Epithelial Cells; Fas Ligand Protein; fas Receptor; Imidazoles; Kidney Glomerulus; Losartan; Membrane Glycoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vasoconstrictor Agents

2002
Interaction between paraventricular nucleus and septal area in the control of physiological responses induced by angiotensin II.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:9

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Drinking; Imidazoles; Losartan; Male; Natriuresis; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Sodium, Dietary; Vasoconstrictor Agents

2002
Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Angiotensin II; Animals; Imidazoles; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

2002
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis

2002
ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Signaling; Cytoplasm; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Kidney Medulla; Losartan; Manganese; Microcirculation; Muscle, Smooth, Vascular; Pericytes; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction; Vasodilator Agents

2003
Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis.
    Circulation research, 2002, Dec-13, Volume: 91, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cardiomyopathies; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix; Fibroblasts; Fibrosis; Imidazoles; Losartan; Matrix Metalloproteinase 2; Proline; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha; Up-Regulation

2002
Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Homeostasis; Imidazoles; Immune Sera; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Time Factors

2003
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arginine Vasopressin; Benzoquinones; Calcium; Cysteine; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Losartan; Myocardium; Propionates; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spectrometry, Fluorescence

2003
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function.
    Circulation research, 2003, Feb-21, Volume: 92, Issue:3

    Topics: Adenosine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; In Vitro Techniques; Losartan; Microcirculation; NADPH Oxidases; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxides; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System

2003
Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells.
    Wiener klinische Wochenschrift, 2002, Aug-30, Volume: 114, Issue:15-16

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Flow Cytometry; Humans; Imidazoles; In Situ Nick-End Labeling; In Vitro Techniques; Kidney Failure, Chronic; Kidney Tubules; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2002
Angiotensin II-induced release of oxytocin: interaction with norepinephrine and role in lactation.
    Regulatory peptides, 2003, Mar-28, Volume: 111, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Suckling; Female; Imidazoles; Injections, Intraventricular; Lactation; Losartan; Norepinephrine; Oxytocin; Phentolamine; Pyridines; Rats; Third Ventricle

2003
The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception.
    Regulatory peptides, 2003, Mar-28, Volume: 111, Issue:1-3

    Topics: Angiotensin II; Animals; Avoidance Learning; Disease Models, Animal; Drug Combinations; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Memory; Mice; Pain Measurement; Pentylenetetrazole; Pyridines; Seizures; Tail

2003
Role of the angiotensin II system in regulation of ovulation and blood flow in the rat ovary.
    Reproduction (Cambridge, England), 2003, Volume: 125, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dinoprostone; Drug Synergism; Female; Imidazoles; Laser-Doppler Flowmetry; Losartan; Ovary; Ovulation; Plasminogen Activators; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow

2003
Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.
    Brain research, 2003, Apr-04, Volume: 968, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Functional Laterality; Ganglionectomy; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Nodose Ganglion; Oligopeptides; Pyridines; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Solitary Nucleus

2003
Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats.
    The international journal of biochemistry & cell biology, 2003, Volume: 35, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Losartan; Male; Minoxidil; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

2003
Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR.
    Journal of molecular and cellular cardiology, 2003, Volume: 35, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Fibroblasts; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardium; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2003
Influence of angiotensin II receptor subtypes of the paraventricular nucleus on the physiological responses induced by angiotensin II injection into the medial septal area.
    Arquivos brasileiros de cardiologia, 2003, Volume: 80, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Drinking; Homeostasis; Imidazoles; Losartan; Male; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Saralasin; Septum of Brain; Sodium; Vasoconstrictor Agents

2003
Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:2

    Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2003
Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jun-15, Volume: 23, Issue:12

    Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Immunohistochemistry; In Vitro Techniques; Losartan; Male; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Spinal Cord; Synaptophysin

2003
Angiotensin II and III microinjections into the zona incerta influence drinking behavior.
    Brain research, 2003, Jul-11, Volume: 977, Issue:2

    Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Interactions; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Pyridines; Rats; Subthalamus; Time Factors

2003
Responses to GABA-A receptor blockade in the hypothalamic PVN are attenuated by local AT1 receptor antagonism.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; GABA-A Receptor Antagonists; Heart Rate; Imidazoles; Kidney; Losartan; Male; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, GABA-A; Sympathetic Nervous System

2003
Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.
    Circulation research, 2003, Sep-05, Volume: 93, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Blotting, Western; Cell Line; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Losartan; Lymphokines; Neovascularization, Physiologic; Oligopeptides; Pertussis Toxin; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors

2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis.
    Circulation, 2003, Sep-23, Volume: 108, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Cells, Cultured; Connective Tissue Growth Factor; Drug Administration Routes; Drug Administration Schedule; Extracellular Matrix Proteins; Female; Fibrosis; Gene Expression; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; Infusion Pumps, Implantable; Intercellular Signaling Peptides and Proteins; Losartan; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger

2003
Patients with steroid refractory acute vascular rejection develop agonistic antibodies targeting angiotensin II type 1 receptor.
    Transplantation proceedings, 2003, Volume: 35, Issue:6

    Topics: Acute Disease; Adrenal Cortex Hormones; Angiotensin II Type 1 Receptor Blockers; Antibody Formation; Biopsy; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Humans; Imidazoles; Immunoglobulin G; Immunosuppressive Agents; Kidney Transplantation; Losartan; Major Histocompatibility Complex; Mycophenolic Acid; Pyridines; Receptor, Angiotensin, Type 1

2003
Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.
    Circulation, 2003, Nov-11, Volume: 108, Issue:19

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Hypertrophic; Fibroblast Growth Factor 1; Gene Expression Regulation; Genes, fos; Heart Rate; Hypertension; Imidazoles; Infusion Pumps, Implantable; Losartan; Male; Natriuretic Peptide, Brain; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Vascular Endothelial Growth Factor A

2003
Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:2

    Topics: alpha-Amylases; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Ceruletide; Imidazoles; Inflammation; Losartan; NADPH Oxidases; Organ Size; Oxygen; Pancreas; Pancreatitis; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2004
Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.
    Diabetologia, 2004, Volume: 47, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Blotting, Western; Dose-Response Relationship, Drug; Gene Expression; Glucose; Imidazoles; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Losartan; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Peptidyl-Dipeptidase A; Proinsulin; Protein Biosynthesis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction

2004
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomyopathy, Hypertrophic; Coronary Vessels; Disease Models, Animal; Enzyme Induction; Imidazoles; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Ventricular Remodeling

2004
Angiotensin type-1 receptor blockade increases ACE 2 expression in the heart.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Down-Regulation; Enzyme Induction; Heart; Humans; Imidazoles; Losartan; Mice; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Tetrazoles

2004
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.
    Brain research, 2004, May-01, Volume: 1006, Issue:2

    Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine

2004
Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney.
    Nephron. Experimental nephrology, 2004, Volume: 96, Issue:3

    Topics: Angiotensin Receptor Antagonists; Animals; Apoptosis; bcl-2-Associated X Protein; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley

2004
The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis.
    Regulatory peptides, 2004, Jul-15, Volume: 119, Issue:3

    Topics: Acute Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Ceruletide; Enzymes; Gene Expression Regulation, Enzymologic; Imidazoles; Losartan; Pancreas; Pancreatitis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstrictor Agents

2004
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction

2004
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.
    Circulation research, 2004, Jun-25, Volume: 94, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents

2004
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:6

    Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation

2004
Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.
    Regulatory peptides, 2004, Aug-15, Volume: 120, Issue:1-3

    Topics: Adjuvants, Immunologic; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Imidazoles; Kidney Cortex; Losartan; Peptide Fragments; Pertussis Toxin; Pyridines; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents

2004
Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Adenine; Angiotensin II; Animals; Blotting, Western; CD13 Antigens; Drug Interactions; Glutamyl Aminopeptidase; Imidazoles; Losartan; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Peptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Thiorphan

2004
Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression.
    Brain research. Molecular brain research, 2004, Sep-10, Volume: 128, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Death; Cell Line; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Losartan; N-Methylaspartate; Neurons; Proto-Oncogene Proteins c-bcl-2; Pyridines; Receptors, Angiotensin; Receptors, N-Methyl-D-Aspartate; Vasoconstrictor Agents

2004
Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catecholamines; Cell Line; Delayed Rectifier Potassium Channels; Imidazoles; Locus Coeruleus; Losartan; Mice; Naphthalenes; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sulfonamides; Type C Phospholipases

2004
Angiotensin II-dependent induction of AT(2) receptor expression after renal ablation.
    American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Diuresis; Gene Expression Regulation; Imidazoles; Kidney; Ligation; Losartan; Male; Nephrectomy; Proteinuria; Pyridines; Ramipril; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Artery; RNA, Messenger

2005
Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.
    Kidney & blood pressure research, 2005, Volume: 28, Issue:1

    Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WF; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents

2005
ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.
    Biochemical and biophysical research communications, 2004, Dec-10, Volume: 325, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cell Line; Chemokine CCL2; Chemokines; Down-Regulation; Drug Interactions; Endothelium, Vascular; Humans; Imidazoles; Interleukin-8; Losartan; Monocytes; NF-kappa B; Peptidyl-Dipeptidase A; Pyridines; Ramipril; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Simvastatin; Umbilical Veins

2004
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
    Circulation research, 2004, Dec-10, Volume: 95, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan

2004
Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:4

    Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Deglutition; Drinking; Electromyography; Female; Fetus; Imidazoles; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sheep

2005
Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.
    The Journal of endocrinology, 2004, Volume: 183, Issue:3

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Azaserine; Cell Line; Gene Expression Regulation; Glucose; Imidazoles; Indicators and Reagents; Indoles; Insulin; Kidney Tubules, Proximal; Losartan; Maleimides; Perindopril; Protein Kinase C; Pyridines; Rats; Reactive Oxygen Species; Renin

2004
Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists.
    Regulatory peptides, 2005, Apr-15, Volume: 127, Issue:1-3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Calcium-Transporting ATPases; Cells, Cultured; Dose-Response Relationship, Drug; Imidazoles; Kidney Tubules, Proximal; Losartan; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sheep; Vasoconstrictor Agents

2005
NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II.
    Circulation research, 2005, Apr-01, Volume: 96, Issue:6

    Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Calcium Signaling; Catalase; Cells, Cultured; Cyclic N-Oxides; Delayed Rectifier Potassium Channels; Drinking Behavior; Glycoproteins; Heart Rate; Hypothalamus; Imidazoles; Injections, Intraventricular; Ion Channel Gating; Losartan; Male; NADPH Oxidases; Neurons; Polyethylene Glycols; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Spin Labels; Telemetry; Xanthine; Xanthine Oxidase

2005
Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arachidonic Acid; Bone Marrow Cells; Cells, Cultured; Humans; Imidazoles; Losartan; Macaca fascicularis; Macrophage Colony-Stimulating Factor; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stromal Cells

2004
The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas.
    Clinical endocrinology, 2005, Volume: 62, Issue:4

    Topics: Adenoma; ADP-ribosyl Cyclase; Adrenal Cortex Neoplasms; Aldosterone; Angiotensins; Case-Control Studies; Cyclic ADP-Ribose; Cytochrome P-450 CYP11B2; Dose-Response Relationship, Drug; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured

2005
The effect of angiotensin III on protein tyrosine kinase activity in rat pituitary.
    Regulatory peptides, 2005, Aug-15, Volume: 130, Issue:1-2

    Topics: Angiotensin II; Angiotensin III; Animals; CD13 Antigens; Imidazoles; Losartan; Methionine; Peptides; Pituitary Gland; Protein Binding; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2005
Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:8

    Topics: Angiotensin II; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Epithelial Cells; Gene Expression Regulation; Glomerulonephritis, IGA; Humans; Imidazoles; Immunoblotting; Immunoglobulin A; Immunohistochemistry; Inflammation; Interleukin-6; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Kinetics; Losartan; MAP Kinase Signaling System; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Poly(ADP-ribose) Polymerases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recombinant Proteins; Renin-Angiotensin System; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation

2005
ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells.
    Life sciences, 2005, Aug-26, Volume: 77, Issue:15

    Topics: Alkaline Phosphatase; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Calcimycin; Calcium; Cell Line; Cell Proliferation; Deoxyglucose; DNA-Binding Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Estrenes; Gene Expression; Glucose Transporter Type 1; Imidazoles; Inositol Phosphates; Losartan; Membrane Transport Proteins; Mice; Monosaccharide Transport Proteins; Neomycin; Octamer Transcription Factor-3; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Pyrrolidinones; Stem Cells; Transcription Factors; Type C Phospholipases; Vasoconstrictor Agents

2005
Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II.
    Peptides, 2005, Volume: 26, Issue:9

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen Type I; Culture Media, Serum-Free; Fibroblasts; Gene Expression; Humans; Imidazoles; Losartan; Myocytes, Smooth Muscle; Procollagen; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Vasoconstrictor Agents

2005
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla.
    Circulation research, 2005, Oct-14, Volume: 97, Issue:8

    Topics: Angiotensin II; Animals; Blood Pressure; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Losartan; Male; Medulla Oblongata; NADPH Oxidases; Oligonucleotides, Antisense; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxides; Sympathetic Nervous System

2005
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Drug Synergism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents

2005
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
    American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Astrocytes; Carboxypeptidases; Cells, Cultured; Cerebellum; Female; Gene Expression Regulation; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2006
Role of angiotensin II receptor subtypes in porcine basilar artery: functional, radioligand binding, and cell culture studies.
    Life sciences, 2006, Jan-25, Volume: 78, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Basilar Artery; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Female; Imidazoles; In Vitro Techniques; Indicators and Reagents; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Nitroarginine; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine

2006
Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats.
    Journal of hypertension, 2005, Volume: 23, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Fructose; Glucose; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin Resistance; Liver; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2

2005
AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arsenicals; Cells, Cultured; Colchicine; Colforsin; Cyclic AMP; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Kidney Tubules, Proximal; Losartan; Microtubules; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sucrose

2006
Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.
    Nephron. Experimental nephrology, 2006, Volume: 103, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Coculture Techniques; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Green Fluorescent Proteins; Heparin-binding EGF-like Growth Factor; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Losartan; Metalloproteases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Phosphorylation; Podocytes; Protease Inhibitors; Pyridines; Recombinant Fusion Proteins; Time Factors; Transcriptional Activation

2006
Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:4

    Topics: Adaptation, Physiological; Amidines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Dinoprostone; Hydroxyeicosatetraenoic Acids; Imidazoles; Indomethacin; Losartan; Male; Microcirculation; Nephrectomy; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents

2006
Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses.
    Peptides, 2006, Volume: 27, Issue:9

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Female; Fetus; Hypothalamus; Imidazoles; Injections, Intraventricular; Losartan; Pregnancy; Proto-Oncogene Proteins c-fos; Pyridines; Sheep; Time Factors; Vasopressins

2006
Angiotensin II disrupts inhibitory avoidance memory retrieval.
    Hormones and behavior, 2006, Volume: 50, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anxiety; Avoidance Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Imidazoles; Losartan; Male; Memory; Motor Activity; Pyridines; Rats; Rats, Wistar

2006
Biphasic actions of angiotensin IV on renal blood flow in the rat.
    Regulatory peptides, 2006, Sep-11, Volume: 136, Issue:1-3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Kidney; Losartan; Male; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regional Blood Flow; Vasodilator Agents

2006
Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro.
    Acta physiologica (Oxford, England), 2006, Volume: 188, Issue:1

    Topics: Adrenergic Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atropine; Blotting, Western; Cholinergic Antagonists; Dose-Response Relationship, Drug; Female; Guanethidine; Humans; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Species Specificity

2006
Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.
    Atherosclerosis, 2007, Volume: 192, Issue:2

    Topics: Angiotensin II; Atherosclerosis; Cathepsin F; Cathepsins; Cell Survival; Humans; Imidazoles; Losartan; Macrophages; Pyridines; Receptor, Angiotensin, Type 2

2007
Translocation of AT1- and AT2-receptors by higher concentrations of angiotensin II in the smooth muscle cells of rat internal anal sphincter.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Anal Canal; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biotin; Blotting, Western; Cytosol; Fluorescent Antibody Technique; Imidazoles; In Vitro Techniques; Losartan; Male; Microscopy, Confocal; Muscle, Smooth; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic

2006
Angiotensin II regulates extraneuronal dopamine uptake in the kidney.
    Nephron. Physiology, 2006, Volume: 104, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dopamine; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; In Vitro Techniques; Kidney; Kidney Tubules, Proximal; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium; Temperature; Time Factors

2006
The role of angiotensin II in stress urinary incontinence: A rat model.
    Neurourology and urodynamics, 2007, Volume: 26, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Imidazoles; Losartan; Peripheral Nerve Injuries; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Vasoconstrictor Agents

2007
Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism.
    Neuropeptides, 2006, Volume: 40, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Animals; Convulsants; Desipramine; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Mice; Mice, Inbred ICR; Norepinephrine; Pentylenetetrazole; Pyridines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Restraint, Physical; Seizures; Stress, Psychological; Sympathetic Nervous System

2006
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:2

    Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Vectors; Hypertension; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Time Factors; Transduction, Genetic; Up-Regulation

2007
[Alteration of signal transduction-associated gene expression in rat cardiac fibroblasts induced by blocking angiotensin II receptors].
    Sheng li xue bao : [Acta physiologica Sinica], 2006, Dec-25, Volume: 58, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Fibroblasts; Gene Expression; Imidazoles; Losartan; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction

2006
Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.
    Endocrinology, 2007, Volume: 148, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Chemokine CCL2; Diabetes Mellitus, Type 1; Gene Expression; Hyperglycemia; Imidazoles; Insulin-Secreting Cells; Insulinoma; Interleukin-1beta; Losartan; Mice; Mice, Inbred NOD; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Pyridines; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstrictor Agents

2007
Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain.
    Brain research, 2007, Apr-27, Volume: 1143

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Binding, Competitive; Brain; Drug Interactions; Imidazoles; Iodine Isotopes; Losartan; p-Chloromercuribenzoic Acid; Pyridines; Rats; Rats, Sprague-Dawley

2007
17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors.
    European journal of pharmacology, 2007, Jul-19, Volume: 567, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Estradiol; Estrogen Antagonists; Fibroblasts; Fulvestrant; Heart; Imidazoles; Indicators and Reagents; Losartan; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: Acetophenones; Allopurinol; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Drug Antagonism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Onium Compounds; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxides

2007
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:4

    Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoles; Indoles; Leukostasis; Losartan; Male; NADPH Oxidases; Pyridines; Pyrroles; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Diseases; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents

2007
Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Imidazoles; Interleukin-1beta; Interleukin-6; Ligation; Losartan; Male; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha

2007
Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.
    Biochemical and biophysical research communications, 2007, Nov-23, Volume: 363, Issue:3

    Topics: alpha-Synuclein; Angiotensin II; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Immunoblotting; Inclusion Bodies; Losartan; Parkinson Disease; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents

2007
Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries.
    Neuroscience, 2007, Dec-12, Volume: 150, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Enteric Nervous System; Ganglia, Spinal; Imidazoles; Losartan; Mesenteric Artery, Superior; Nerve Fibers; Nerve Growth Factor; Nerve Regeneration; Neuropeptide Y; Norepinephrine; Phenol; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sclerosing Solutions; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2007
The effect of angiotensin II and IV on ERK1/2 and CREB signalling in cultured rat astroglial cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 376, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Apoptosis; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Pyridines; Rats; Receptors, Angiotensin; Vasoconstrictor Agents

2007
The role of angiotensin II in the early stages of bovine ovulation.
    Reproduction (Cambridge, England), 2007, Volume: 134, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Cattle; Female; Gonadotropin-Releasing Hormone; Imidazoles; Injections; Losartan; Luteinizing Hormone; Ovarian Follicle; Ovulation; Pyridines; Random Allocation; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Saralasin; Ultrasonography

2007
Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.
    Endocrine, 2007, Volume: 32, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Losartan; Neovascularization, Physiologic; Peptide Fragments; Pyridines; Receptors, Angiotensin; Umbilical Veins; Vasoconstrictor Agents

2007
Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2008, Volume: 12, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Progression; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Humans; Imidazoles; Immunohistochemistry; Losartan; Mitogen-Activated Protein Kinase 1; Neovascularization, Pathologic; Pancreatic Neoplasms; Protein Kinase Inhibitors; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents

2008
Role of the renin angiotensin system in TNF-alpha and Shiga-toxin-induced tissue factor expression.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Endothelium, Vascular; Humans; Imidazoles; Kidney Glomerulus; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Shiga Toxin 1; Thromboplastin; Tumor Necrosis Factor-alpha; Up-Regulation

2008
[The influence of angiotensin II receptor blockade on the expressions of Col I and TIMP-1 mRNA in cardiac fibroblast of adult rat].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Collagen Type I; Fibroblasts; Imidazoles; Losartan; Myocardium; Pyridines; Rats; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2007
Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium; Enzyme Inhibitors; Female; Imidazoles; Losartan; Mesenteric Arteries; Nicotine; Nicotinic Agonists; Nitroarginine; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sex Characteristics; Vasoconstriction; Vasoconstrictor Agents

2008
Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.
    Cardiovascular research, 2008, Jun-01, Volume: 78, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Cholesterol Esters; Disease Models, Animal; Humans; Hypertension; Imidazoles; Lactoferrin; Losartan; Low Density Lipoprotein Receptor-Related Protein-1; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Up-Regulation

2008
Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.
    Pediatric research, 2008, Volume: 63, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Coronary Vessels; Dexamethasone; Endothelium, Vascular; Female; Glucocorticoids; Imidazoles; Losartan; NADP; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Sheep; Superoxides; Vasoconstriction; Vasoconstrictor Agents

2008
Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:1

    Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2008
Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Arteries; Cattle; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2008
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.
    European journal of pharmacology, 2008, Jun-24, Volume: 588, Issue:1

    Topics: Abnormalities, Drug-Induced; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Animals, Newborn; Autoradiography; Female; Imidazoles; Kidney; Kidney Glomerulus; Losartan; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System

2008
Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization.
    Neuroendocrinology, 2008, Volume: 88, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Basal Nucleus of Meynert; Cerebral Cortex; Female; Imidazoles; Losartan; Nucleus Accumbens; Olfactory Bulb; Putamen; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Solitary Nucleus; Subfornical Organ; Substantia Nigra; Ventral Tegmental Area

2008
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents

2008
Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides.
    Life sciences, 2008, Sep-12, Volume: 83, Issue:11-12

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Binding Sites; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Female; Humans; Imidazoles; Ligands; Losartan; Male; Middle Aged; p-Chloromercuribenzoic Acid; Peptides; Protease Inhibitors; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sex Characteristics

2008
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:1

    Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation

2009
Regulation of T-cell function by endogenously produced angiotensin II.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:2

    Topics: Adoptive Transfer; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Autocrine Communication; Blood Pressure; Catalase; Cells, Cultured; Homeodomain Proteins; Imidazoles; Infusion Pumps, Implantable; Losartan; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Polyethylene Glycols; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Superoxide Dismutase; Superoxides; T-Lymphocytes; Time Factors; Tumor Necrosis Factor-alpha

2009
Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Imidazoles; Losartan; Mice; Mice, Transgenic; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System

2009
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phenylephrine; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2009
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.
    Endocrinology, 2009, Volume: 150, Issue:9

    Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Down-Regulation; Female; Gene Expression; Humans; Imidazoles; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stereoisomerism; Uterus

2009
Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization.
    Experimental neurology, 2009, Volume: 220, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Autoradiography; Female; Fetus; Imidazoles; Losartan; Mice; Pregnancy; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Rhombencephalon; RNA, Messenger; Vasoconstrictor Agents

2009
Angiotensin II receptors are expressed and functional in human esophageal mucosa.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:5

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biopsy; Biphenyl Compounds; Blood Vessels; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Esophagus; Female; Gene Expression; Humans; Hydrochloric Acid; Imidazoles; Losartan; Male; Middle Aged; Mucous Membrane; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2009
Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Endocardium; Female; Imidazoles; Infusions, Intravenous; Losartan; Male; Myocardial Ischemia; Myocardium; Purkinje Fibers; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tachycardia, Ventricular; Time Factors

2009
Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.
    Journal of hypertension, 2010, Volume: 28, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Bartter Syndrome; Cells, Cultured; Drug Combinations; Dual Specificity Phosphatase 1; Female; Fibroblasts; Gitelman Syndrome; Humans; Hypertension; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2010
Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system.
    Behavioural brain research, 2010, Mar-05, Volume: 207, Issue:2

    Topics: Acute Disease; Amygdala; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Female; Imidazoles; Losartan; Motor Activity; Oocytes; Proestrus; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Restraint, Physical; Sexual Behavior, Animal; Stress, Psychological; Time Factors

2010
Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Glucose; Imidazoles; Insulin; Insulin-Secreting Cells; Ion Channel Gating; Losartan; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Potassium; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Shab Potassium Channels; Signal Transduction; Time Factors

2010
Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Enzyme Inhibitors; Female; Imidazoles; Kidney Cortex; Leucine; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Reactive Oxygen Species; Receptors, Angiotensin; Sheep; Time Factors

2010
Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Flow Velocity; Blood Glucose; Blood Pressure Determination; Blood Volume; Disease Models, Animal; Imidazoles; Infusions, Intravenous; Losartan; Male; Microcirculation; Muscle, Skeletal; Probability; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstrictor Agents

2010
Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Cell Line; Cell Proliferation; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyridines; Quinazolines; Rats; Receptors, Angiotensin; Transcriptional Activation; Tyrphostins

2009
Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Blood Pressure; Cell Proliferation; Cells, Cultured; Chronic Disease; Collagen; Disease Models, Animal; Fibrinolysin; Fibrosis; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nephrectomy; Phosphorylation; Plasminogen Activator Inhibitor 1; Podocytes; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Time Factors

2010
The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts.
    Free radical biology & medicine, 2010, Jul-01, Volume: 49, Issue:1

    Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Hyperoxia; Imidazoles; Losartan; Lung; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Small Interfering; Signal Transduction

2010
Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.
    Journal of cellular physiology, 2010, Volume: 225, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Imidazoles; Losartan; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Vasoconstrictor Agents

2010
The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Basigin; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Losartan; Macrophages; Nitrobenzenes; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Sulfonamides

2010
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:4

    Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitroprusside; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2010
Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).
    Cellular signalling, 2010, Volume: 22, Issue:12

    Topics: Angiotensin II; Animals; Female; Gene Expression Regulation; Heterogeneous-Nuclear Ribonucleoprotein K; Hyperglycemia; Imidazoles; Kidney; Kidney Cortex; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A

2010
Angiotensin II enhances connecting tubule glomerular feedback.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:4

    Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterioles; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Feedback, Physiological; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Kidney Tubules; Losartan; Microcirculation; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Sodium Channel Blockers; Sodium Chloride; Vasoconstrictor Agents; Vasodilation

2010
AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:4

    Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Benzophenanthridines; Catalase; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Glutathione Peroxidase; Hypothalamus; Imidazoles; Injections, Intraventricular; Losartan; Male; NADPH Oxidases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium; Superoxide Dismutase; Water

2010
Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein.
    Peptides, 2011, Volume: 32, Issue:1

    Topics: Angiotensin II; Animals; Femoral Vein; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Receptor, Angiotensin, Type 1; Vasoconstriction; Vena Cava, Inferior

2011
Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.
    Regulatory peptides, 2011, Jan-17, Volume: 166, Issue:1-3

    Topics: alpha-Amylases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Cell Line; Ceruletide; Enzyme Activation; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Pancreas, Exocrine; Pancreatitis; Pyridines; Rats; Receptor, Angiotensin, Type 1

2011
Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Movement; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Imidazoles; Insulin; Losartan; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Phosphatidylinositol 3-Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Up-Regulation

2011
Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.
    Brain research, 2011, Jan-12, Volume: 1368

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes

2011
Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway.
    Peptides, 2011, Volume: 32, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Hypertrophic; Extracellular Fluid; Gene Expression; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Myocardial Contraction; Peptide Fragments; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reflex, Stretch

2011
Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apelin; Captopril; Cells, Cultured; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Losartan; Mice; Perindopril; Pyridines; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger

2011
Intracellular angiotensin II activates rat myometrium.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arsenicals; Autophagy; Brefeldin A; Calcium Signaling; Carbolines; Cells, Cultured; Egtazic Acid; Endocytosis; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Estrenes; Female; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Lysosomes; Macrocyclic Compounds; Macrolides; Models, Biological; Myometrium; NADP; Oxazoles; Piperazines; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ryanodine; Saralasin; Signal Transduction; Sirolimus; Type C Phospholipases; Uterus

2011
Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Pyridines; Quinolones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sulfones; Swine; Time Factors

2011
Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.
    Neuropeptides, 2011, Volume: 45, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Flavonoids; Imidazoles; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley

2011
Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Cells, Cultured; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Serine; Signal Transduction; Tyrosine

2011
Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size.
    Cytokine, 2011, Volume: 56, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Captopril; Heart Rate; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Pyridines; Rats; Rats, Wistar; Risk Factors

2011
Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.
    Neurobiology of learning and memory, 2012, Volume: 97, Issue:1

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Hippocampus; Imidazoles; Losartan; Mice; Mice, Knockout; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Recognition, Psychology

2012
Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.
    Experimental physiology, 2012, Volume: 97, Issue:9

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Cardiovascular System; Chymases; Heart Rate; Imidazoles; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Sympathetic Nervous System; Vagotomy; Vagus Nerve

2012
Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Proliferation; Cells, Cultured; Gene Expression; Humans; Imidazoles; Losartan; Podocytes; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha

2012
The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.
    Journal of vascular research, 2012, Volume: 49, Issue:2

    Topics: Animals; Collateral Circulation; Down-Regulation; Guanidines; Hypertension, Portal; Imidazoles; Ligation; Liver Cirrhosis; Losartan; Male; Nitric Oxide Synthase; Nitroarginine; Portal Vein; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction

2012
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
    Regulatory peptides, 2012, Aug-20, Volume: 177, Issue:1-3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Losartan; MAP Kinase Signaling System; Mesangial Cells; Microscopy, Confocal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transforming Growth Factor beta1

2012
Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.
    Regulatory peptides, 2012, Aug-20, Volume: 177, Issue:1-3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; beta-Galactosidase; Blotting, Western; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Assays; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Stilbenes; Tumor Suppressor Protein p53

2012
Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.
    Regulatory peptides, 2012, Aug-20, Volume: 177, Issue:1-3

    Topics: Allosteric Regulation; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Binding, Competitive; Calcium-Transporting ATPases; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Assays; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Kidney Tubules, Proximal; Losartan; Oligopeptides; Phosphorylation; Protein Binding; Protein Conformation; Pyridines; Receptor, Angiotensin, Type 2; Sheep; Signal Transduction; Transfection

2012
The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Animals; Captopril; Cell Proliferation; Diethylstilbestrol; Estrogens; Gene Expression Regulation; Hyperplasia; Imidazoles; Immunohistochemistry; Losartan; Male; Neovascularization, Pathologic; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Endothelial Growth Factor A

2012
Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses.
    Experimental physiology, 2013, Volume: 98, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Arterial Pressure; Captopril; Chymases; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylethanolamine N-Methyltransferase; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System

2013
Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Absorption; Angiotensin II Type 2 Receptor Blockers; Animals; Disease Models, Animal; Hypertension; Imidazoles; Loop of Henle; Losartan; Male; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1

2012
Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:8

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bucladesine; Calcium; Cell Line; Chelating Agents; Dactinomycin; Drug Interactions; Egtazic Acid; Estrenes; Gallic Acid; Gene Expression Regulation; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Losartan; Nucleic Acid Synthesis Inhibitors; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Type C Phospholipases

2012
Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation.
    Peptides, 2012, Volume: 37, Issue:2

    Topics: Angiotensin II; Angiotensin III; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Imidazoles; Losartan; Male; Prostatic Neoplasms; Pyridines; Structure-Activity Relationship

2012
Intake of high sucrose during pregnancy altered large-conductance Ca2+-activated K+ channels and vessel tone in offspring's mesenteric arteries.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:2

    Topics: Angiotensin II; Animals; Animals, Newborn; Dietary Carbohydrates; Dose-Response Relationship, Drug; Female; Imidazoles; Large-Conductance Calcium-Activated Potassium Channels; Losartan; Membrane Potentials; Mesenteric Arteries; Models, Animal; Muscle, Smooth, Vascular; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sucrose

2013
Angiotensin II induces the production of MMP-3 and MMP-13 through the MAPK signaling pathways via the AT(1) receptor in osteoblasts.
    Biochimie, 2013, Volume: 95, Issue:4

    Topics: Alkaline Phosphatase; Angiotensin II; Animals; Cell Line, Tumor; Cell Proliferation; Gelatin; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Mice; Osteoblasts; Phosphorylation; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tissue Inhibitor of Metalloproteinases

2013
Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB.
    Differentiation; research in biological diversity, 2013, Volume: 85, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Differentiation; Cell Line; Collagen; Embryonic Stem Cells; Imidazoles; Losartan; Mice; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Sulfones

2013
[Effects of angiotensin II and its receptor blockers on migration and endothelin-1 expression of rat vascular adventitial fibroblast subpopulations].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Movement; Cells, Cultured; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents

2012
Angiotensin III stimulates high stretch-induced ANP secretion via angiotensin type 2 receptor.
    Peptides, 2013, Volume: 42

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Atrial Natriuretic Factor; Dose-Response Relationship, Drug; Heart Atria; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Losartan; Male; Myocardial Contraction; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction

2013
Angiotensin AT(1)-receptor blockers enhance cardiac responses to parasympathetic nerve stimulation via presynaptic AT(1) receptors in pithed rats.
    Journal of pharmacological sciences, 2013, Volume: 122, Issue:1

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradycardia; Electric Stimulation; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Presynaptic; Tetrazoles; Vagus Nerve

2013
Angiotensin II type 1 receptor blockade restores angiotensin-(1-7)-induced coronary vasodilation in hypertrophic rat hearts.
    Clinical science (London, England : 1979), 2013, Volume: 125, Issue:9

    Topics: Angiotensin I; Animals; Cardiomegaly; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Vasodilation

2013
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats.
    Journal of hypertension, 2013, Volume: 31, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sympathetic Nervous System

2013
Angiotensin AT2 receptor agonist stimulates high stretch induced- ANP secretion via PI3K/NO/sGC/PKG/pathway.
    Peptides, 2013, Volume: 47

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Atrial Pressure; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Guanylate Cyclase; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Nitric Oxide; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Tissue Culture Techniques; Vasodilator Agents

2013
Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release.
    Biochemical pharmacology, 2013, Sep-01, Volume: 86, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Dopamine; Hypothalamus; Imidazoles; In Vitro Techniques; Losartan; Male; Nicotine; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tritium

2013
Angiotensin II produces nociceptive behavior through spinal AT1 receptor-mediated p38 mitogen-activated protein kinase activation in mice.
    Molecular pain, 2013, Jul-31, Volume: 9

    Topics: Angiotensin II; Animals; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Spinal Cord

2013
Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Female; Imidazoles; Lipopolysaccharides; Losartan; Nitric Oxide Synthase Type II; Pre-Eclampsia; Pregnancy; Prostaglandins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents

2013
Angiotensin III induces signal transducer and activator of transcription 3 and interleukin-6 mRNA levels in cultured rat astrocytes.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:4

    Topics: Angiotensin III; Animals; Astrocytes; Cells, Cultured; Cyclic S-Oxides; DNA; Gene Expression Regulation; Imidazoles; Interleukin-6; Losartan; Phosphorylation; Pyridines; Rats, Sprague-Dawley; RNA, Messenger; STAT3 Transcription Factor; Time Factors

2015
Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor.
    Biochemical and biophysical research communications, 2014, Aug-22, Volume: 451, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Line; Endothelin-1; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Up-Regulation; Vasoconstriction

2014
Vascular effects of a tripeptide fragment of novokinine in hypertensive rats: Mechanism of the hypotensive action.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Infusions, Intravenous; Losartan; Male; Norepinephrine; Oligopeptides; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Circulation; Vasoconstriction

2014
Activation of upregulated angiotensin II type 2 receptors decreases carotid pulse pressure in rats with suprarenal abdominal aortic coarctation.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:4

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Coarctation; Blood Pressure; Blotting, Western; Carotid Arteries; Disease Models, Animal; Gene Expression Regulation; Hypertension; Imidazoles; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation

2015
Role of Mas receptor antagonist (A779) on pressure diuresis and natriuresis and renal blood flow in the absence of angiotensin II receptors type 1 and 2 in female and male rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Diuresis; Female; Imidazoles; Kidney; Losartan; Male; Natriuresis; Peptide Fragments; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Circulation; Sex Factors; Vascular Resistance

2014
Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury.
    Scientific reports, 2014, Nov-13, Volume: 4

    Topics: Acute Lung Injury; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Gene Expression; Humans; Imidazoles; Influenza A Virus, H7N9 Subtype; Losartan; Lung; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Survival Analysis; Viral Load

2014
Angiotensin receptor I stimulates osteoprogenitor proliferation through TGFβ-mediated signaling.
    Journal of cellular physiology, 2015, Volume: 230, Issue:7

    Topics: Angiotensin II Type 2 Receptor Blockers; Angiotensins; Animals; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mesenchymal Stem Cells; Mice; Osteoblasts; Pyridines; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta

2015
Characterization and functions of vascular adventitial fibroblast subpopulations.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:3

    Topics: Adventitia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Lineage; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; RNA, Messenger

2015
Losartan reverses the down-expression of long noncoding RNA-NR024118 and Cdkn1c induced by angiotensin II in adult rat cardiac fibroblasts.
    Pathologie-biologie, 2015, Volume: 63, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p57; Down-Regulation; Fibroblasts; Imidazoles; Losartan; Male; Myocardium; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Long Noncoding

2015
Dietary Sodium Suppresses Digestive Efficiency via the Renin-Angiotensin System.
    Scientific reports, 2015, Jun-11, Volume: 5

    Topics: Animals; Dietary Fats; Digestion; Gene Deletion; Imidazoles; Intestinal Absorption; Losartan; Male; Mice; Pyridines; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium Chloride, Dietary

2015
Role of Mas receptor antagonist (A779) in renal hemodynamics in condition of blocked angiotensin II receptors in rats.
    Physiology international, 2016, Volume: 103, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Female; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Organ Size; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Regional Blood Flow

2016
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
    The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23

    Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2016
Angiotensin II induces interleukin-6 expression in astrocytes: Role of reactive oxygen species and NF-κB.
    Molecular and cellular endocrinology, 2016, 12-05, Volume: 437

    Topics: Angiotensin II; Animals; Astrocytes; Brain; Female; Gene Expression Regulation; Hydrazones; Imidazoles; Interleukin-6; Losartan; NF-kappa B; Nitroimidazoles; Pyridines; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Time Factors

2016
Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain.
    Pain, 2016, Volume: 157, Issue:12

    Topics: Analgesics; Analysis of Variance; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Imidazoles; Losartan; Mice; Mice, Inbred BALB C; Nesting Behavior; Peptide Fragments; Pyridines; Rotarod Performance Test

2016
The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats.
    Journal of hypertension, 2017, Volume: 35, Issue:2

    Topics: Administration, Intravenous; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Body Fluids; Brain; Enzyme Inhibitors; Heart Rate; Imidazoles; Infusions, Intraventricular; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Receptor, Angiotensin, Type 2; Sodium Chloride; Sympathetic Nervous System

2017
Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice.
    Peptides, 2017, Volume: 88

    Topics: Adiponectin; Adipose Tissue; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Chemokine CCL2; Diabetes Mellitus, Type 2; Humans; Hypertension; Imidazoles; Insulin; Insulin Resistance; Interleukin-6; Losartan; Mice; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tumor Necrosis Factor-alpha

2017
Functions of AT1 and AT2 angiotensin receptors in the paraventricular nucleus of the rat, correlating single-unit and cardiovascular responses.
    Brain research bulletin, 2017, Volume: 132

    Topics: Action Potentials; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cardiovascular Agents; Heart Rate; Imidazoles; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2017
Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5-8) injected into the rat ventrolateral periaqueductal gray.
    Peptides, 2017, Volume: 96

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anxiety; Imidazoles; Losartan; Male; Periaqueductal Gray; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1

2017
Angiotensin II facilitates GABAergic neurotransmission at postsynaptic sites in rat amygdala neurons.
    Neuropharmacology, 2018, 05-01, Volume: 133

    Topics: Amygdala; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Agents; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Losartan; Male; Mice; Neurotransmitter Agents; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Vasoconstrictor Agents

2018
AT2R (Angiotensin II Type 2 Receptor)-Mediated Regulation of NCC (Na-Cl Cotransporter) and Renal K Excretion Depends on the K Channel, Kir4.1.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Imidazoles; Ion Transport; Kidney Tubules, Distal; Losartan; Mice; Mice, Knockout; Potassium Channels, Inwardly Rectifying; Pyridines; Receptor, Angiotensin, Type 2; Sodium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3; Water-Electrolyte Imbalance

2018
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN.
    Neuropharmacology, 2018, Volume: 135

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antidepressive Agents; Captopril; Carbazoles; Cells, Cultured; Cerebral Cortex; Enalapril; Hippocampus; Imidazoles; Immobility Response, Tonic; Indole Alkaloids; Losartan; Male; Mice; Microinjections; Prefrontal Cortex; Proto-Oncogene Proteins c-fyn; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptor, trkB; Transcriptional Activation

2018
Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:9

    Topics: Angiogenesis Inducing Agents; Angiogenic Proteins; Angiotensin II; Gene Expression Regulation; Humans; Imidazoles; Losartan; Neovascularization, Pathologic; NF-kappa B; Proto-Oncogene Mas; Pyridines; Receptor, Angiotensin, Type 1; Transcription Factor RelA; Transcriptional Activation

2018
A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2 signalling pathways.
    Experimental dermatology, 2019, Volume: 28, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anthracenes; Bone Marrow Cells; Cell Differentiation; Cell Lineage; Cell Movement; Imidazoles; Janus Kinase 2; Janus Kinases; Keratinocytes; Losartan; Male; MAP Kinase Signaling System; Mesenchymal Stem Cells; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tyrphostins

2019
Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway.
    IUBMB life, 2019, Volume: 71, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Butadienes; Cell Survival; Cycloheximide; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; Nitriles; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha

2019
Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Aortic Aneurysm; Aortitis; Biomechanical Phenomena; Captopril; Constriction; Hypertension; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Random Allocation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Vascular Remodeling

2019
Analysis of angiotensin II-Induced rat urinary bladder contractions in the presence of angiotensin II receptors blockers.
    Archives of physiology and biochemistry, 2021, Volume: 127, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Homeostasis; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Stress, Mechanical; Urinary Bladder

2021
Angiotensin II triggers autophagy and apoptosis in PC12 cell line: An in vitro Alzheimer's disease model.
    Brain research, 2019, 09-01, Volume: 1718

    Topics: Alzheimer Disease; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Autophagy; Imidazoles; Losartan; Models, Biological; Neurodegenerative Diseases; PC12 Cells; Pyridines; Rats; Receptor, Angiotensin, Type 1

2019
Angiotensin II type 2 receptor blocker PD123319 has more beneficial effects than losartan on ischemia-reperfusion injury and oxidative damage in isolated rat heart.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:12

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Myocardial Reperfusion Injury; Oxidative Stress; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2

2019
AT
    Pflugers Archiv : European journal of physiology, 2019, Volume: 471, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Corticomedial Nuclear Complex; Heart; Heart Rate; Imidazoles; Losartan; Male; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled

2019
Methylation-reprogrammed AGTR1 results in increased vasoconstriction by angiotensin II in human umbilical cord vessel following in vitro fertilization-embryo transfer.
    Life sciences, 2019, Oct-01, Volume: 234

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; DNA Methylation; Embryo Transfer; Female; Fertilization in Vitro; Humans; Imidazoles; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Umbilical Cord; Vasoconstriction; Vasoconstrictor Agents

2019
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice.
    Scientific reports, 2019, 12-19, Volume: 9, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Necroptosis; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction

2019
AT2R's (Angiotensin II Type 2 Receptor's) Role in Cognitive and Cerebrovascular Deficits in a Mouse Model of Alzheimer Disease.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:6

    Topics: Alzheimer Disease; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Cognition; Disease Models, Animal; Imidazoles; Losartan; Mice; Neuroimmunomodulation; Neurovascular Coupling; Plaque, Amyloid; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sulfonamides; Thiophenes; Vasodilation

2020
Angiotensinergic receptors in the medial amygdaloid nucleus differently modulate behavioral responses in the elevated plus-maze and forced swimming test in rats.
    Behavioural brain research, 2021, 01-15, Volume: 397

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Corticomedial Nuclear Complex; Imidazoles; Losartan; Male; Maze Learning; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Swimming

2021
Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload.
    International heart journal, 2021, Jan-30, Volume: 62, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cardiomegaly; Case-Control Studies; Constriction; HMGB1 Protein; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Pyridines; Up-Regulation; Vasoconstrictor Agents

2021